Search Results - "BIRMINGHAM, Anne"

Cyclodextrin-Derived Diorganyl Tellurides as Glutathione Peroxidase Mimics and Inhibitors of Thioredoxin Reductase and Cancer Cell Growth by McNaughton, Michael, Engman, Lars, Birmingham, Anne, Powis, Garth, Cotgreave, Ian A

“…Water-soluble diorganyl tellurides of the alkyl aryl or dialkyl type were prepared by treatment of mono-6-tosyl-β-cyclodextrin with sodium alkanetellurolates…”
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Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase by Powis, Garth, Wipf, Peter, Lynch, Stephen M, Birmingham, Anne, Kirkpatrick, D Lynn

“…The cytosolic thioredoxin redox system composed of thioredoxin-1 and the NADPH-dependent thioredoxin reductase-1 reductase is an important regulator of cell…”
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Natural product based inhibitors of the thioredoxin-thioredoxin reductase system by Wipf, Peter, Lynch, Stephen M, Birmingham, Anne, Tamayo, Giselle, Jiménez, Allan, Campos, Nefertiti, Powis, Garth

“…Spiroketal naphthodecalins are readily assembled by Barton's base mediated Ullmann binaphthyl ether coupling, Dakin reactions and hypervalent iodine…”
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Thioredoxin reductase and cancer cell growth inhibition by organotellurium antioxidants by Engman, Lars, Al-Maharik, Nawaf, McNaughton, Michael, Birmingham, Anne, Powis, Garth

“…Thioredoxin (Trx) expression is increased in several human primary cancers and the Trx/Trx reductase (TrxR) system therefore provides an attractive target for…”
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New inhibitors of the thioredoxin–thioredoxin reductase system based on a naphthoquinone spiroketal natural product lead by Wipf, Peter, Hopkins, Tamara D., Jung, Jae-Kyu, Rodriguez, Sonia, Birmingham, Anne, Southwick, Eileen C., Lazo, John S., Powis, Garth

“…Natural products of the naphthoquinone spiroketal structural type served as lead structures for the development of novel inhibitors of the…”
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Effects of the dopamine reuptake inhibitor PTT on reinstatement and on food- and cocaine-maintained responding in rhesus monkeys by LILE, Joshua A, MORGAN, Drake, BIRMINGHAM, Anne M, DAVIES, Huw M. L, NADER, Michael A

“…High-affinity, slow-onset, long-acting dopamine transporter (DAT) inhibitors are being considered as potential agonist replacement therapies for cocaine…”
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Further evaluation of the reinforcing effects of the novel cocaine analog 2β-propanoyl-3β-(4-tolyl)-tropane (PTT) in rhesus monkeys by BIRMINGHAM, A. M, NADER, S. H, GRANT, K. A, DAVIES, H. M. L, NADER, M. A

“…2β-Propanoyl-3β-(4-tolyl)-tropane (PTT) is a cocaine analog which has been shown in rhesus monkeys to have cocaine-like discriminative stimulus effects and a…”
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Thioredoxin reductase and cancer cell growth inhibition by organogold(III) compounds by Engman, Lars, McNaughton, Michael, Gajewska, Malgorzata, Kumar, Sangit, Birmingham, Anne, Powis, Garth

“…Thioredoxin (Trx) expression is increased in several human primary cancers associated with aggressive tumor growth and decreased patient survival, and the…”
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Thioredoxin reductase and cancer cell growth inhibition by organotellurium compounds that could be selectively incorporated into tumor cells by ENGMAN, Lars, AL-MAHARIK, Nawaf, MCNAUGHTON, Michael, BIRMINGHAM, Anne, POWIS, Garth

“…The thioredoxins are small ubiquitous redox proteins with the conserved redox catalytic sequence-Trp-Cys-Gly-Pro-Cys-Lys, where the Cys residues undergo…”
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Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system by Wipf, Peter, Lynch, Stephen M, Powis, Garth, Birmingham, Anne, Englund, Erikah E

“…A series of palmarumycin prodrugs and water-soluble analogs has been synthesized and assayed for inhibition of the thioredoxin-thioredoxin reductase system…”
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The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation by Welsh, Sarah J, Williams, Ryan R, Birmingham, Anne, Newman, David J, Kirkpatrick, D Lynn, Powis, Garth

“…Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that plays a critical role in tumor growth by increasing resistance to apoptosis and the…”
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The reinforcing efficacy of the dopamine reuptake inhibitor 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT) as measured by a progressive-ratio schedule and a choice procedure in rhesus monkeys by Lile, Joshua A, Morgan, Drake, Birmingham, Anne M, Wang, Zhixia, Woolverton, William L, Davies, Huw M L, Nader, Michael A

“…The present series of experiments was undertaken to investigate the variables that influence the reinforcing efficacy of psychostimulants. The time of onset…”
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COGNITIVE STYLE AND STUDENTS' ABILITY TO PERFORM READING TASKS IN CONTENT AREAS by BIRMINGHAM, ANNE

“…This investigation revolved around four major variables: cognitive style (field-dependence, field-independence); reading tasks (main idea, major details,…”
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