Search Results - "BINETTI, Giuliano"
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1
Effects of Transcranial Direct Current Stimulation on Episodic Memory in Amnestic Mild Cognitive Impairment: A Pilot Study
Published in The journals of gerontology. Series B, Psychological sciences and social sciences (13-08-2020)“…Abstract Objectives Episodic memory is impaired in amnestic mild cognitive impairment (aMCI), which is posited as a potential prodromal form of Alzheimer’s…”
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2
Frontotemporal dementia and its subtypes: a genome-wide association study
Published in Lancet neurology (01-07-2014)“…Summary Background Frontotemporal dementia (FTD) is a complex disorder characterised by a broad range of clinical manifestations, differential pathological…”
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3
Loss of Neuroprotective Factors in Neurodegenerative Dementias: The End or the Starting Point?
Published in Frontiers in neuroscience (01-12-2017)“…Recent clinical, genetic and biochemical experimental evidences highlight the existence of common molecular pathways underlying neurodegenerative diseases. In…”
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4
Cognitive reserve predicts episodic memory enhancement induced by transcranial direct current stimulation in healthy older adults
Published in Scientific reports (28-02-2024)“…Episodic memory shows the largest degree of age-related decline. Anodal transcranial Direct Current Stimulation (tDCS) can enhance episodic memory in aging but…”
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5
Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease
Published in Annals of neurology (01-04-2014)“…Objective Meta‐analyses show that nonbound ceruloplasmin (non‐Cp) copper (also known as free or labile copper) in serum is higher in patients with Alzheimer…”
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tDCS-Induced Memory Reconsolidation Effects: Analysis of Prominent Predicting Factors
Published in Frontiers in neuroscience (17-03-2022)“…Memory impairment is among one of the greatest cognitive complaints in midlife and in old age. Considering the importance of good memory functioning in…”
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Unveiling New Genetic Variants Associated with Age at Onset in Alzheimer's Disease and Frontotemporal Lobar Degeneration Due to C9orf72 Repeat Expansions
Published in International journal of molecular sciences (07-07-2024)“…Alzheimer's disease (AD) and Frontotemporal lobar degeneration (FTLD) represent the most common forms of neurodegenerative dementias with a highly phenotypic…”
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Mutational Landscape of Alzheimer's Disease and Frontotemporal Dementia: Regional Variances in Northern, Central, and Southern Italy
Published in International journal of molecular sciences (27-06-2024)“…Alzheimer's Disease (AD) and Frontotemporal Dementia (FTD) are the two major neurodegenerative diseases with distinct clinical and neuropathological profiles…”
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Effectiveness of an Innovative Cognitive Treatment and Telerehabilitation on Subjects With Mild Cognitive Impairment: A Multicenter, Randomized, Active-Controlled Study
Published in Frontiers in aging neuroscience (16-11-2020)“…In recent years, the potential usefulness of cognitive training procedures in normal aging and mild cognitive impairment (MCI) have received increased…”
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10
Language training for oral and written naming impairment in primary progressive aphasia: a review
Published in Translational neurodegeneration (16-07-2021)“…Primary progressive aphasia (PPA) is a neurodegenerative disorder characterized by a gradual, insidious and progressive loss of language abilities, with naming…”
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11
Copper Imbalance in Alzheimer's Disease: Meta-Analysis of Serum, Plasma, and Brain Specimens, and Replication Study Evaluating ATP7B Gene Variants
Published in Biomolecules (Basel, Switzerland) (29-06-2021)“…Evidence indicates that patients with Alzheimer's dementia (AD) show signs of copper (Cu) dyshomeostasis. This study aimed at evaluating the potential of Cu…”
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12
Autophagy Markers Are Altered in Alzheimer's Disease, Dementia with Lewy Bodies and Frontotemporal Dementia
Published in International journal of molecular sciences (01-01-2024)“…The accumulation of protein aggregates defines distinct, yet overlapping pathologies such as Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and…”
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13
The Missing Heritability of Sporadic Frontotemporal Dementia: New Insights from Rare Variants in Neurodegenerative Candidate Genes
Published in International journal of molecular sciences (10-08-2019)“…Frontotemporal dementia (FTD) is a common form of dementia among early-onset cases. Several genetic factors for FTD have been revealed, but a large proportion…”
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14
Serum Beta-Secretase 1 Activity Is a Potential Marker for the Differential Diagnosis between Alzheimer's Disease and Frontotemporal Dementia: A Pilot Study
Published in International journal of molecular sciences (01-08-2024)“…Alzheimer's disease (AD) and frontotemporal dementia (FTD) are the two major neurodegenerative diseases causing dementia. Due to similar clinical phenotypes,…”
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15
Role for ATXN1, ATXN2, and HTT intermediate repeats in frontotemporal dementia and Alzheimer's disease
Published in Neurobiology of aging (01-03-2020)“…We analyzed the frequency of intermediate alleles (IAs) in the ATXN1, ATXN2, and HTT genes in several neurodegenerative diseases. The study included 1126…”
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Strengthening of Existing Episodic Memories Through Non-invasive Stimulation of Prefrontal Cortex in Older Adults with Subjective Memory Complaints
Published in Frontiers in aging neuroscience (05-12-2017)“…Episodic memory is critical to daily life functioning. This type of declarative memory declines with age and is the earliest cognitive function to be…”
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Eating Behavior in Aging and Dementia: The Need for a Comprehensive Assessment
Published in Frontiers in nutrition (Lausanne) (16-12-2020)“…Eating behavior can change during aging due to physiological, psychological, and social changes. Modifications can occur at different levels: (1) in food…”
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The PINK1 p.Asn521Thr Variant Is Associated with Earlier Disease Onset in GRN/C9orf72 Frontotemporal Lobar Degeneration
Published in International journal of molecular sciences (01-11-2022)“…Genetic frontotemporal lobar degeneration (FTLD) is characterized by heterogeneous phenotypic expression, with a disease onset highly variable even in patients…”
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Plasma Small Extracellular Vesicle Cathepsin D Dysregulation in GRN/C9orf72 and Sporadic Frontotemporal Lobar Degeneration
Published in International journal of molecular sciences (14-09-2022)“…Emerging data suggest the roles of endo-lysosomal dysfunctions in frontotemporal lobar degeneration (FTLD) and in other dementias. Cathepsin D is one of the…”
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N-Terminally Truncated and Pyroglutamate-Modified Aβ Forms Are Measurable in Human Cerebrospinal Fluid and Are Potential Markers of Disease Progression in Alzheimer’s Disease
Published in Frontiers in neuroscience (29-07-2021)“…Alzheimer’s disease (AD) is a pathology characterized by the accumulation in the brain of intracellular and extracellular amyloid-β (Aβ) aggregates, especially…”
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