Search Results - "BIGBEE, W. L"

Activation of the Nitric Oxide Synthase 2 Pathway in the Response of Bone Marrow Stromal Cells to High Doses of Ionizing Radiation by Gorbunov, Nikolai V., Pogue-Geile, Katherine L., Epperly, Michael W., Bigbee, William L., Draviam, Romesh, Day, Billy W., Wald, Niel, Watkins, Simon C., Greenberger, Joel S.

“…Gorbunov, N. V., Pogue-Geile, K. L., Epperly, M. W., Bigbee, W. L., Draviam, R., Day, B. W., Wald, N., Watkins, S. C. and Greenberger, J. S. Activation of the…”
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Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes by MOSER, M. J, BIGBEE, W. L, GRANT, S. G, EMOND, M. J, LANGLOIS, R. G, JENSEN, R. H, OSHIMA, J, MONNAT, R. J

“…Werner syndrome (WRN) is an uncommon autosomal recessive disease in which progeroid features are associated with genetic instability and an elevated risk of…”
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Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer by ITZKOWITZ, S. H, MEI YUAN, MONTGOMERY, C. K, KJELDSEN, T, TAKAHASHI, H. K, BIGBEE, W. L, KIM, Y. S

“…Mucin glycoproteins are major secretory products of the colon and contain O-linked oligosaccharides synthesized on a polypeptide backbone. The initial step in…”
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Evidence for Increased in vivo Mutation and Somatic Recombination in Bloom's Syndrome by Langlois, Richard G., Bigbee, William L., Jensen, Ronald H., German, James

“…The glycophorin A assay was used to estimate the frequency of mutations that accumulate in vivo in somatic cells of persons with Bloom's syndrome (BS). This…”
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Elevated Frequency of Glycophorin A Mutations in Erythrocytes from Chernobyl Accident Victims by Jensen, Ronald H., Langlois, Richard G., Bigbee, William L., Grant, Stephen G., Moore, Dan, Pilinskaya, Maria, Vorobtsova, Irena, Pleshanov, Pavel

“…In 1986, when an explosion accident occurred at the Chernobyl, Ukraine nuclear power plant, a large number of people were exposed to significant amounts of…”
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Radiobiological evaluation of immigrants from the vicinity of Chernobyl by LIVINGSTON, G. K, JENSEN, R. H, SILBERSTEIN, E. B, HINNEFELD, J. D, PRATT, G, BIGBEE, W. L, LANGLOIS, R. G, GRANT, S. G, SHUKLA, R

“…Eighty individuals (55 adults and 25 children) who were residents of four cities (Kiev, Mozyr, Gomel and Bobrujsk) located 100-200 km from Chernobyl at the…”
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HPRT and glycophorin A mutations in foundry workers: relationship to PAH exposure and to PAH-DNA adducts by Perera, F P, Tang, D L, O'Neill, J P, Bigbee, W L, Albertini, R J, Santella, R, Ottman, R, Tsai, W Y, Dickey, C, Mooney, L A

“…Mutations were evaluated in workers in an iron foundry with exposure to polycyclic aromatic hydrocarbons (PAHs), measured by personal and area monitoring,…”
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Familial clustering of breast cancer: possible interaction between DNA repair proficiency and radiation exposure in the development of breast cancer by Helzlsouer, K J, Harris, E L, Parshad, R, Fogel, S, Bigbee, W L, Sanford, K K

“…The capacity of peripheral blood lymphocytes to repair X-ray-induced DNA damage, manifest as chromatid damage 30-90 min after G2-phase X-irradiation, was…”
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Evidence for an elevated frequency of in vivo somatic cell mutations in ataxia telangiectasia by BIGBEE, W. L, LANGLOIS, R. G, SWIFT, M, JENSEN, R. H

“…Somatic cell mutation frequency in vivo was measured in individuals with high cancer risk who were from ataxia telangiectasia (A-T) families. The assay for…”
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Biodosimetry for a radiation worker using multiple assays by Straume, T, Lucas, J N, Tucker, J D, Bigbee, W L, Langlois, R G

“…Four state-of-the-art biodosimeters--GPA mutations, chromosome translocations, micronuclei, and dicentrics--were used to evaluate a radiation worker who…”
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Glycophorin A biodosimetry in Chernobyl cleanup workers from the Baltic countries by Bigbee, William L, Jensen, Ronald H, Veidebaum, Toomas, Tekkel, Mare, Rahu, Mati, Stengrevics, Aivars, Kesminiene, Ausrele, Kurtinaitis, Juozas, Auvinen, Anssi, Hakulinen, Timo, Servomaa, Kristina, Rytomaa, Tapio, Obrams, G Iris, Jr, John D Boice

“…The 1986 Chernobyl nuclear accident resulted in massive contamination of the area, necessitating evacuation of the population, extensive environmental cleanup…”
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Biodosimetry of Chernobyl Cleanup Workers from Estonia and Latvia Using the Glycophorin A In Vivo Somatic Cell Mutation Assay by Bigbee, William L., Jensen, Ronald H., Veidebaum, Toomas, Tekkel, Mare, Rahu, Mati, Stengrevics, Aivars, Auvinen, Anssi, Hakulinen, Timo, Servomaa, Kristina, Rytömaa, Tapio, Obrams, G. Iris, Boice, John D.

“…The reactor accident at Chernobyl in 1986 necessitated a massive environmental cleanup that involved over 600,000 workers from all 15 Republics of the former…”
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Thyroid Nodularity and Cancer among Chernobyl Cleanup Workers from Estonia by Inskip, Peter D., Hartshorne, Michael F., Tekkel, Mare, Rahu, Mati, Veidebaum, Toomas, Auvinen, Anssi, Crooks, Lida A., Littlefield, L. Gayle, McFee, Alfred F., Salomaa, Sisko, Mäkinen, Sirpa, Tucker, James D., Sorensen, Karen J., Bigbee, William L., Boice, John D.

“…Thyroid examinations, including palpation, ultrasound and, selectively, fine-needle aspiration biopsy, were conducted on nearly 2,000 Chernobyl cleanup workers…”
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Novel biodosimetry methods applied to victims of the Goiânia accident by Straume, T, Langlois, R G, Lucas, J, Jensen, R H, Bigbee, W L, Ramalho, A T, Brandão-Mello, C E

“…Two biodosimetric methods under development at the Lawrence Livermore National Laboratory were applied to five persons accidentally exposed to a 137Cs source…”
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Glycophorin A somatic cell mutation frequencies in Finnish reinforced plastics workers exposed to styrene by Bigbee, W L, Grant, S G, Langlois, R G, Jensen, R H, Anttila, A, Pfäffli, P, Pekari, K, Norppa, H

“…We have used the glycophorin A (GPA) in vivo somatic cell mutation assay to assess the genotoxic potential of styrene exposure in 47 reinforced plastics…”
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Analysis of Somatic Cell Mutations at the Glycophorin A Locus in Atomic Bomb Survivors: A Comparative Study of Assay Methods by Langlois, R. G., Akiyama, M., Kusunoki, Y., DuPont, B. R., Moore, D. H., Bigbee, W. L., Grant, S. G., Jensen, R. H.

“…The glycophorin A (GPA) assay for in vivo somatic cell mutations was performed on blood samples from 39 survivors of the atomic bomb at Hiroshima. Parallel…”
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Flow cytometric characterization of normal and variant cells with monoclonal antibodies specific for glycophorin A by Langlois, RG, Bigbee, WL, Jensen, RH

“…Quantitative immunofluorescence measurements were performed on erythrocytes labeled with monoclonal antibodies to glycophorin A (GPA) to assess the level of…”
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Use of allele-specific glycophorin A antibodies to enumerate fetal erythroid cells in maternal circulation by Bigbee, W L, Grant, S G

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Evidence for Increased Somatic Cell Mutations at the Glycophorin a Locus in Atomic Bomb Survivors by Langlois, Richard G., Bigbee, William L., Kyoizumi, Seishi, Nakamura, Nori, Bean, Michael A., Akiyama, Mitoshi, Jensen, Ronald H.

“…A recently developed assay for somatic cell mutations was used to study survivors of the atomic bomb at Hiroshima. This assay measures the frequency of variant…”
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Measurements of the frequency of human erythrocytes with gene expression loss phenotypes at the glycophorin A locus by LANGLOIS, R. G, BIGHEE, W. L, JENSEN, R. H

“…An assay method is described for determining the frequency of human erythrocytes having a gene expression loss phenotype at the glycophorin A locus presumably…”
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