Search Results - "BIFULCO, M"

Medical Cannabis: A plurimillennial history of an evergreen by Pisanti, S., Bifulco, M.

“…The history of Cannabis goes along that of humankind, as speculated based on geographical and evolutionary models together with historic data collected to…”
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Mediterranean diet: the missing link between gut microbiota and inflammatory diseases by Bifulco, M

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How does the Mediterranean diet decrease the risk of a variety of cancers? by Bifulco, M

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The obesity and cancer link by Bifulco, M.

“…The existence of a causal link between obesity and cancer incidence could be considered to date not more a mere medical hypothesis but a consolidated…”
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The mystery of longevity in Cilento: a mix of a good dose of genetic predisposition and a balanced diet based on the Mediterranean model by Bifulco, M, Pisanti, S

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Smallpox vaccination and vaccine hesitancy in the Kingdom of the Two Sicilies (1801) and the great modernity of Ferdinand IV of Bourbon: a glimpse of the past in the era of the SARS-COV-2 (COVID-19) pandemic by Martini, M., Bifulco, M., Orsini, D.

“…The current health emergency caused by COVID-19 disease shows several correspondences with well-known epidemics of the past. The knowledge of their management…”
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Gemcitabine cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism by Donadelli, M, Dando, I, Zaniboni, T, Costanzo, C, Dalla Pozza, E, Scupoli, M T, Scarpa, A, Zappavigna, S, Marra, M, Abbruzzese, A, Bifulco, M, Caraglia, M, Palmieri, M

“…Gemcitabine (GEM, 2′,2′-difluorodeoxycytidine) is currently used in advanced pancreatic adenocarcinoma, with a response rate of < 20%. The purpose of our work…”
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Symptoms of alcohol abuse: The first warning sign of cancer development risk by Bifulco, M., Citro, M., Abate, M.

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Dental care and dentistry practice in the Medieval Medical School of Salerno by Bifulco, M., Amato, M., Gangemi, G., Marasco, M., Caggiano, M., Amato, A., Pisanti, S.

“…Key Points The Medieval Medical School of Salerno (9th century) is considered the first institution in the western world for the teaching of medical knowledge…”
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p53 regulates the mevalonate pathway in human glioblastoma multiforme by Laezza, C, D'Alessandro, A, Di Croce, L, Picardi, P, Ciaglia, E, Pisanti, S, Malfitano, A M, Comegna, M, Faraonio, R, Gazzerro, P, Bifulco, M

“…The mevalonate (MVA) pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, we provided evidence that p53…”
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Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm by Aquila, S, Guido, C, Santoro, A, Gazzerro, P, Laezza, C, Baffa, MF, Andò, S, Bifulco, M

“…Background and purpose:  The endocannabinoid system and the cannabinoid CB1 receptor have been identified in human sperm, and it is well known that…”
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Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation by Blondel, S, Egesipe, A-L, Picardi, P, Jaskowiak, A-L, Notarnicola, M, Ragot, J, Tournois, J, Le Corf, A, Brinon, B, Poydenot, P, Georges, P, Navarro, C, pitrez, P R, Ferreira, L, Bollot, G, Bauvais, C, Laustriat, D, Mejat, A, De Sandre-Giovannoli, A, Levy, N, Bifulco, M, Peschanski, M, Nissan, X

“…Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by a dramatic appearance of premature aging. HGPS is due to a single-base…”
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Association between cannabinoid type-1 receptor polymorphism and body mass index in a southern Italian population by Gazzerro, P, Caruso, M.G, Notarnicola, M, Misciagna, G, Guerra, V, Laezza, C, Bifulco, M

“…Context: Endocannabinoids control food intake via both central and peripheral mechanisms, and cannabinoid type-1 receptor (CB1) modulates lipogenesis in…”
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Endocannabinoids in endocrine and related tumours by Bifulco, Maurizio, Malfitano, Anna Maria, Pisanti, Simona, Laezza, Chiara

“…The ‘endocannabinoid system’, comprising the cannabinoid CB1 and CB2 receptors, their endogenous ligands, endocannabinoids and the enzymes that regulate their…”
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Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects by Monteleone, P., Bifulco, M., Di Filippo, C., Gazzerro, P., Canestrelli, B., Monteleone, F., Proto, M. C., Di Genio, M., Grimaldi, C., Maj, M.

“…Endocannabinoids modulate eating behavior; hence, endocannabinoid genes may contribute to the biological vulnerability to eating disorders. The rs1049353 (1359…”
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Rimonabant (SR141716) exerts anti‐proliferative and immunomodulatory effects in human peripheral blood mononuclear cells by Malfitano, A M, Laezza, C, Pisanti, S, Gazzerro, P, Bifulco, M

“…Background and purpose: Rimonabant (SR141716) is the first selective cannabinoid receptor CB1 antagonist described. Along with its anti‐obesity action,…”
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Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells by Sarnataro, Daniela, Grimaldi, Claudia, Pisanti, Simona, Gazzerro, Patrizia, Laezza, Chiara, Zurzolo, Chiara, Bifulco, Maurizio

“…In this report we show, by confocal analysis of indirect immunofluorescence, that the type-1 cannabinoid receptor (CB1R), which belongs to the family of…”
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Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells by Di Marzo, V, Melck, D, Orlando, P, Bisogno, T, Zagoory, O, Bifulco, M, Vogel, Z, De Petrocellis, L

“…Palmitoylethanolamide (PEA) has been shown to act in synergy with anandamide (arachidonoylethanolamide; AEA), an endogenous agonist of cannabinoid receptor…”
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Control by the endogenous cannabinoid system of ras oncogene‐dependent tumor growth by Bifulco, Maurizio, Laezza, Chiara, Portella, Giuseppe, Vitale, Mario, Orlando, Pierangelo, De Petrocellis, Luciano, Di Marzo, Vincenzo

“…ABSTRACT We investigated the effect of 2‐methyl‐arachidonyl‐2′‐fluoro‐ethylamide (Met‐F‐AEA), a stable analog of the endocannabinoid anandamide, on a rat…”
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Unsaturated Long-Chain N-Acyl-vanillyl-amides (N-AVAMs): Vanilloid Receptor Ligands That Inhibit Anandamide-Facilitated Transport and Bind to CB1 Cannabinoid Receptors by Melck, Dominique, Bisogno, Tiziana, De Petrocellis, Luciano, Chuang, Huai-hu, Julius, David, Bifulco, Maurizio, Di Marzo, Vincenzo

“…We investigated the effect of changing the length and degree of unsaturation of the fatty acyl chain of N-(3-methoxy-4-hydroxy)-benzyl-cis-9-octadecenoamide…”
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