Search Results - "BIELSKI, R"
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Effect of the Conjugation Density of Triphenylphosphonium Cation on the Mitochondrial Targeting of Poly(amidoamine) Dendrimers
Published in Molecular pharmaceutics (03-08-2015)“…Many clinically relevant diseases with known poor therapeutic outcomes, including cancer and neurodegenerative disorders, have been directly linked to…”
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Efficacy of pregabalin in generalized social anxiety disorder: results of a double-blind, placebo-controlled, fixed-dose study
Published in International clinical psychopharmacology (01-07-2011)“…The objective of this study was to evaluate the efficacy and tolerability of pregabalin for the treatment of generalized social anxiety disorder (SAD)…”
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Megalin-targeting liposomes for placental drug delivery
Published in Journal of controlled release (10-08-2020)“…Every year, complications during pregnancy affect more than 26 million women. Some of those diseases are associated with significant morbidity and mortality,…”
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A novel bone registration method using impression molding and structured‐light 3D scanning technology
Published in Journal of orthopaedic research (01-10-2022)“…Accurate bone registration is critical for computer navigation and robotic surgery. Existing registration systems are expensive, cumbersome, limited in…”
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Conjugation to Poly(amidoamine) Dendrimers and Pulmonary Delivery Reduce Cardiac Accumulation and Enhance Antitumor Activity of Doxorubicin in Lung Metastasis
Published in Molecular pharmaceutics (05-07-2016)“…Lung is one of the most common sites to which almost all other primary tumors metastasize. The major challenges in the chemotherapy of lung metastases include…”
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A novel method of light projection and modular jigs to improve accuracy in bone sarcoma resection
Published in Journal of orthopaedic research (01-11-2022)“…We developed a novel method using a combined light‐registration/light‐projection system along with an off‐the‐shelf, instant‐assembly modular jig construct…”
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Dendrimer Conjugation Enhances Tumor Penetration and Efficacy of Doxorubicin in Extracellular Matrix-Expressing 3D Lung Cancer Models
Published in Molecular pharmaceutics (04-05-2020)“…Doxorubicin (DOX) is a chemotherapeutic agent broadly used in the treatment of a range of solid tumors. In spite of its high potency, as is the case for many…”
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Nanoparticles of pH-Responsive, PEG–Doxorubicin Conjugates: Interaction with an in Vitro Model of Lung Adenocarcinoma and Their Direct Formulation in Propellant-Based Portable Inhalers
Published in Molecular pharmaceutics (06-11-2017)“…Pulmonary administration of polymer drug conjugates is of great potential clinical significance for treating lung cancer as such regimen significantly…”
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Local Targeting of Lung-Tumor-Associated Macrophages with Pulmonary Delivery of a CSF-1R Inhibitor for the Treatment of Breast Cancer Lung Metastases
Published in Molecular pharmaceutics (07-12-2020)“…The lungs are major sites of metastases for several cancer types, including breast cancer (BC). Prognosis and quality of life of BC patients that develop…”
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Report on a novel bone registration method: A rapid, accurate, and radiation-free technique for computer- and robotic-assisted orthopedic surgeries
Published in Journal of orthopaedics (01-01-2021)“…Computer- and robotic-assisted technologies have recently been introduced into orthopedic surgery to improve accuracy. Each requires intraoperative “bone…”
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A novel intraoperative method to project osteotomy lines for accurate resection of primary bone sarcomas
Published in Journal of orthopaedics (01-07-2022)“…Accurate reproduction of a preoperative plan is critical in wide resection of bone sarcomas. Recent advances in computer navigation and 3D-custom jigs have…”
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Double-blind, placebo-substitution study of nefazodone in the prevention of relapse during continuation treatment of outpatients with major depression
Published in International clinical psychopharmacology (01-01-1999)“…The efficacy of nefazodone in prevention of relapse of depression was evaluated in a 36-week double-blind, placebo-substitution, continuation treatment trial…”
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Pregabalin in Generalized Anxiety Disorder: A Placebo-Controlled Trial
Published in The American journal of psychiatry (01-03-2003)“…OBJECTIVE: Current drug therapies for generalized anxiety disorder have limitations. In a controlled trial, the novel agent pregabalin was studied for the…”
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Flows in random porous media: effective models
Published in Computers and geotechnics (01-01-2003)“…The aim of this paper is to provide a synthesis of results related to modeling transport in random media. Both single and two-phase flows have been considered…”
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Effect of light therapy on salivary melatonin in seasonal affective disorder
Published in Psychiatry research (28-04-1995)“…To investigate the role of a light-induced advance in the timing of the melatonin rhythm in seasonal affective disorder, 11 depressed patients underwent 2…”
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Radiologic Case Study
Published in Orthopedics (Thorofare, N.J.) (01-08-2001)Get full text
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Longitudinal tibial stress fracture
Published in Orthopedics (Thorofare, N.J.) (01-03-1996)“…Fatigue-type stress fractures occur following repetitive loading of normal bone. These occur frequently in the tibia, although vertical orientation to the…”
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Femoral neck fracture following intertrochanteric fracture
Published in The Journal of arthroplasty (01-10-1996)“…Four patients with femoral neck fracture following healed intertrochanteric fracture were evaluated retrospectively. This situation is a rare occurrence with a…”
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Environmental influences on the onset of winter depression
Published in The journal of clinical psychiatry (01-11-1991)Get full text
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