Search Results - "BHANDARI, Vasundhra"

Next-Generation Approaches Needed to Tackle Antimicrobial Resistance for the Development of Novel Therapies Against the Deadly Pathogens by Bhandari, Vasundhra, Suresh, Akash

“…The advent of antimicrobials was a miracle that saved millions of lives across the globe. With the discovery of penicillin, varieties of other antimicrobials…”
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Uncoupling proteins as a therapeutic target for the development of new era drugs against neurodegenerative disorder by Kumar, Rahul, T, Amruthanjali, Singothu, Siva, Singh, Shashi Bala, Bhandari, Vasundhra

“…Mitochondrial uncoupling proteins (UCP) are a part of the large family of mitochondrial solute carriers (SLC25s), concentrated in the inner mitochondrial…”
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Elucidation of Cellular Mechanisms Involved in Experimental Paromomycin Resistance in Leishmania donovani by BHANDARI, Vasundhra, SUNDAR, Shyam, DUJARDIN, Jean Claude, SALOTRA, Poonam

“…Leishmania donovani is the causative agent of the potentially fatal disease visceral leishmaniasis (VL). Chemotherapeutic options available to treat VL are…”
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Repurposing of Food and Drug Admnistration (FDA) approved library to identify a potential inhibitor of trypanothione synthetase for developing an antileishmanial agent by Vemula, Divya, Mohanty, Shreelekha, Bhandari, Vasundhra

“…Leishmaniasis is one of the top 10 neglected tropical diseases. Globally, it impacts more than 12 million individuals. In light of the absence of a safer,…”
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Prevalence and Characterization of Oxacillin Susceptible mecA-Positive Clinical Isolates of Staphylococcus aureus Causing Bovine Mastitis in India by Mistry, Hiral, Sharma, Paresh, Mahato, Sudipta, Saravanan, R, Kumar, P Anand, Bhandari, Vasundhra

“…Bovine mastitis caused by multidrug resistant Staphylococcus aureus is a huge problem reported worldwide, resulting in prolonged antibiotic treatment and death…”
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Homology modeling, virtual screening, molecular docking, and dynamics studies for discovering Staphylococcus epidermidis FtsZ inhibitors by Vemula, Divya, Maddi, Dhanashri Ramesh, Bhandari, Vasundhra

“…is the most common cause of medical device-associated infections and is an opportunistic biofilm former. Among hospitalized patients, infections are the most…”
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Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress by Deep, Deepak Kumar, Singh, Ruchi, Bhandari, Vasundhra, Verma, Aditya, Sharma, Vanila, Wajid, Saima, Sundar, Shyam, Ramesh, V, Dujardin, Jean Claude, Salotra, Poonam

“…Miltefosine (MIL) is an oral antileishmanial drug used for treatment of visceral leishmaniasis (VL) in the Indian subcontinent. Recent reports indicate a…”
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Genetic Profiling Reveals High Allelic Diversity, Heterozygosity and Antigenic Diversity in the Clinical Isolates of the Theileria annulata From India by Roy, Sonti, Bhandari, Vasundhra, Dandasena, Debabrata, Murthy, Shweta, Sharma, Paresh

“…Tropical theileriosis caused by infection is a significant livestock disease affecting cattle health and productivity resulting in substantial monetary losses…”
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Unveiling the antimicrobial action of MMV676501, MMV687807, and MMV102872 against Staphylococcus aureus: A mechanistic investigation by Suresh, Akash, Brahma, Umarani, Bhandari, Vasundhra, Sharma, Paresh

“…[Display omitted] •The impact of the 3 MMV compounds (MMV 676501, MMV 687807 and MMV 102872) on S. aureus transcriptome has been described for the first…”
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Population Genetic Analysis of the Theileria annulata Parasites Identified Limited Diversity and Multiplicity of Infection in the Vaccine From India by Roy, Sonti, Bhandari, Vasundhra, Barman, Madhumanti, Kumar, Pankaj, Bhanot, Vandna, Arora, Jaspreet Singh, Singh, Satparkash, Sharma, Paresh

“…Apicomplexan parasite causes significant economic loss to the livestock industry in India and other tropical countries. In India, parasite control is mainly…”
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Linezolid resistant coagulase negative staphylococci (LRCoNS) with novel mutations causing blood stream infections (BSI) in India by Mittal, Gajanand, Bhandari, Vasundhra, Gaind, Rajni, Rani, Vandana, Chopra, Shimpi, Dawar, Reetika, Sardana, Raman, Verma, P K

“…Coagulase-negative Staphylococci (CoNS) have emerged as a major causative agent of blood-stream infections (BSI). Linezolid (LZD) is currently used for…”
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Epidrugs: alternative chemotherapy targeting Theileria annulata schizont stage parasites by Kamble, Sonam, Singh, Sakshi, Suresh, Akash, Singothu, Siva, Dandesena, Debabrata, Bhandari, Vasundhra, Sharma, Paresh

“…The growing emergence of resistance to current anti-theilerial agents necessitates the exploration of alternative approaches to drug discovery. This study…”
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Antitheilerial Activity of the Anticancer Histone Deacetylase Inhibitors by Barman, Madhumanti, Kamble, Sonam, Roy, Sonti, Bhandari, Vasundhra, Singothu, Siva, Dandasena, Debabrata, Suresh, Akash, Sharma, Paresh

“…The apicomplexan parasite, Theileria annulata , is the most prevalent hemoprotozoan in livestock, causing significant economic losses worldwide. It is…”
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Artemisinin derivatives induce oxidative stress leading to DNA damage and caspase-mediated apoptosis in Theileria annulata-transformed cells by Barman, Madhumanti, Dandasena, Debabrata, Suresh, Akash, Bhandari, Vasundhra, Kamble, Sonam, Singh, Sakshi, Subudhi, Madhusmita, Sharma, Paresh

“…Bovine theileriosis caused by the eukaryotic parasite Theileria annulata is an economically important tick-borne disease. If it is not treated promptly, this…”
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Identification of Variable Traits among the Methicillin Resistant and Sensitive Coagulase Negative Staphylococci in Milk Samples from Mastitic Cows in India by Mahato, Sudipta, Mistry, Hiral U, Chakraborty, Shalini, Sharma, Paresh, Saravanan, R, Bhandari, Vasundhra

“…Methicillin resistant causing bovine mastitis has been very well investigated worldwide. However, there are only limited reports on the characterization of…”
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Novel pyrimidine-piperazine hybrids as potential antimicrobial agents: in-vitro antimicrobial and in-silico studies by Rejinthala, Swathi, Endoori, Srinivas, Vemula, Divya, Bhandari, Vasundhra, Mondal, T.

“…[Display omitted] A series of new pyrimidine-piperazine hybrid molecules ware designed and synthesized as possible antimicrobial agents. The synthesized…”
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Dysbiosis of Gut Microbiota from the Perspective of the Gut-Brain Axis: Role in the Provocation of Neurological Disorders by Kandpal, Meenakshi, Indari, Omkar, Baral, Budhadev, Jakhmola, Shweta, Tiwari, Deeksha, Bhandari, Vasundhra, Pandey, Rajan Kumar, Bala, Kiran, Sonawane, Avinash, Jha, Hem Chandra

“…The gut-brain axis is a bidirectional communication network connecting the gastrointestinal tract and central nervous system. The axis keeps track of…”
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Correction: Prevalence and Characterization of Oxacillin Susceptible mecA-Positive Clinical Isolates of Staphylococcus aureus Causing Bovine Mastitis in India by Mistry, Hiral, Sharma, Paresh, Mahato, Sudipta, Saravanan, R, Kumar, P Anand, Bhandari, Vasundhra

“…[This corrects the article DOI: 10.1371/journal.pone.0162256.]…”
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Antibiotic Resistance and Molecular Profiling of the Clinical Isolates of Staphylococcus aureus Causing Bovine Mastitis from India by Brahma, Umarani, Suresh, Akash, Murthy, Shweta, Bhandari, Vasundhra, Sharma, Paresh

“…is an opportunistic bacterium known to cause severe infections in humans and animals. It is one of the major bacteria causing subclinical and clinical…”
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Potential Sabotage of Host Cell Physiology by Apicomplexan Parasites for Their Survival Benefits by Chakraborty, Shalini, Roy, Sonti, Mistry, Hiral Uday, Murthy, Shweta, George, Neena, Bhandari, Vasundhra, Sharma, Paresh

“…, and are the major apicomplexan parasites affecting humans or animals worldwide. These pathogens represent an excellent example of host manipulators who can…”
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