Search Results - "BHAN, Ishir"

Vitamin D Binding Protein and Bone Health by Bhan, Ishir

“…Vitamin D binding protein (DBP) is the major carrier protein of 25-hydroxyvitamin D (25(OH) D) in the circulation, where it may serve roles in maintaining…”
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Vitamin D–Binding Protein and Vitamin D Status of Black Americans and White Americans by Powe, Camille E, Evans, Michele K, Wenger, Julia, Zonderman, Alan B, Berg, Anders H, Nalls, Michael, Tamez, Hector, Zhang, Dongsheng, Bhan, Ishir, Karumanchi, S. Ananth, Powe, Neil R, Thadhani, Ravi

“…This study shows that a polymorphism in the vitamin D–binding protein gene that is associated with low levels of vitamin D–binding protein among blacks results…”
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Nusinersen initiated in infants during the presymptomatic stage of spinal muscular atrophy: Interim efficacy and safety results from the Phase 2 NURTURE study by De Vivo, Darryl C., Bertini, Enrico, Swoboda, Kathryn J., Hwu, Wuh-Liang, Crawford, Thomas O., Finkel, Richard S., Kirschner, Janbernd, Kuntz, Nancy L., Parsons, Julie A., Ryan, Monique M., Butterfield, Russell J., Topaloglu, Haluk, Ben-Omran, Tawfeg, Sansone, Valeria A., Jong, Yuh-Jyh, Shu, Francy, Staropoli, John F., Kerr, Douglas, Sandrock, Alfred W., Stebbins, Christopher, Petrillo, Marco, Braley, Gabriel, Johnson, Kristina, Foster, Richard, Gheuens, Sarah, Bhan, Ishir, Reyna, Sandra P., Fradette, Stephanie, Farwell, Wildon

“…•NURTURE is an ongoing study of nusinersen started in a presymptomatic stage of SMA.•All infants were ≥25 months old, and alive without permanent…”
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VDR Attenuates Acute Lung Injury by Blocking Ang-2-Tie-2 Pathway and Renin-Angiotensin System by Kong, Juan, Zhu, Xiangdong, Shi, Yongyan, Liu, Tianjing, Chen, Yunzi, Bhan, Ishir, Zhao, Qun, Thadhani, Ravi, Li, Yan Chun

“…Acute lung injury (ALI) is a hallmark of systemic inflammation associated with high mortality. Although the vitamin D receptor (VDR) is highly expressed in the…”
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Ergocalciferol and Cholecalciferol in CKD by Nigwekar, Sagar U., MD, Bhan, Ishir, MD, MPH, Thadhani, Ravi, MD, MPH

“…The development of chronic kidney disease (CKD) is accompanied by a progressive decrease in the ability to produce 1,25-dihydroxyvitamin D. Pharmacological…”
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Vitamin D–binding protein modifies the vitamin D–bone mineral density relationship by Powe, Camille E, Ricciardi, Catherine, Berg, Anders H, Erdenesanaa, Delger, Collerone, Gina, Ankers, Elizabeth, Wenger, Julia, Karumanchi, S Ananth, Thadhani, Ravi, Bhan, Ishir

“…Studies examining the relationship between total circulating 25‐hydroxyvitamin D [25(OH)D] levels and bone mineral density (BMD) have yielded mixed results…”
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Hyponatremia, Mineral Metabolism, and Mortality in Incident Maintenance Hemodialysis Patients: A Cohort Study by Nigwekar, Sagar U., MD, Wenger, Julia, MPH, Thadhani, Ravi, MD, MPH, Bhan, Ishir, MD, MPH

“…Background Hyponatremia is associated with increased mortality in chronic diseases. Recent animal studies also implicate hyponatremia in bone abnormalities…”
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Subclinical Hypothyroidism and Survival: The Effects of Heart Failure and Race by Rhee, Connie M, Curhan, Gary C, Alexander, Erik K, Bhan, Ishir, Brunelli, Steven M

“…Context: Studies examining the association between subclinical hypothyroidism and mortality have yielded conflicting results. Emerging data suggest these…”
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Changes in Kidney Function After Transjugular Intrahepatic Portosystemic Shunts Versus Large-Volume Paracentesis in Cirrhosis: A Matched Cohort Analysis by Allegretti, Andrew S., MD, Ortiz, Guillermo, MD, Cui, Jie, MD, Wenger, Julia, MPH, Bhan, Ishir, MD, MPH, Chung, Raymond T., MD, Thadhani, Ravi I., MD, MPH, Irani, Zubin, MBBS

“…Background Patients with cirrhosis and refractory ascites have physiologic and hormonal dysregulation that contributes to decreased kidney function. Placement…”
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The incidence of hydrocephalus among patients with and without spinal muscular atrophy (SMA): Results from a US electronic health records study by Viscidi, Emma, Wang, Nasha, Juneja, Maneesh, Bhan, Ishir, Prada, Claudia, James, Dayle, Lallier, Stacie, Makepeace, Corinne, Laird, Karen, Eaton, Susan, Dilley, Anne, Hall, Susan

“…The incidence of hydrocephalus in the spinal muscular atrophy (SMA) population relative to the general population is currently unknown. Since the approval of…”
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Breaking Down the Vitamin D–GFR Relationship by Bhan, Ishir, MD, MPH

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Hypothyroidism and Mortality among Dialysis Patients by Rhee, Connie M, Alexander, Erik K, Bhan, Ishir, Brunelli, Steven M

“…Hypothyroidism is highly prevalent among ESRD patients, but its clinical significance and the benefits of thyroid hormone replacement in this context remain…”
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Vitamin D―Binding Protein and Vitamin D Status of Black Americans and White Americans by POWE, Camille E, EVANS, Michele K, POWE, Neil R, THADHANI, Ravi, WENGER, Julia, ZONDERMAN, Alan B, BERG, Anders H, NALLS, Michael, TAMEZ, Hector, DONGSHENG ZHANG, BHAN, Ishir, ANANTH KARUMANCHI, S

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Vascular Calcification and ESRD: A Hard Target by Bhan, Ishir, Thadhani, Ravi

“…End-stage renal disease (ESRD) is associated with both accelerated cardiovascular disease and alterations in vitamin D and mineral metabolism. Calcification of…”
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Development and analytical validation of a novel bioavailable 25-hydroxyvitamin D assay by Berg, Anders H, Tavasoli, Mahtab, Lo, Agnes S, Burnett-Bowie, Sherri-Ann M, Bhan, Ishir, Karumanchi, S Ananth, Kalim, Sahir, Zhang, Dongsheng, Zhao, Sophia, Thadhani, Ravi I

“…Bioavailable 25-hydroxyvitamin D (25OHD) may be a better indicator of vitamin D sufficiency than total 25OHD. This report describes a novel assay for measuring…”
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Low Plasma Level of Cathelicidin Antimicrobial Peptide (hCAP18) Predicts Increased Infectious Disease Mortality in Patients Undergoing Hemodialysis by Gombart, Adrian F., Bhan, Ishir, Borregaard, Niels, Tamez, Hector, Camargo, Carlos A., Koeffler, H. Phillip, Thadhani, Ravi

“…Background. Human cathelicidin antimicrobial protein (hCAP18) is an antimicrobial and immunomodulatory peptide that has pleiotropic effects and is…”
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Therapeutic Effects of Vitamin D Analogs on Cardiac Hypertrophy in Spontaneously Hypertensive Rats by Kong, Juan, Kim, Gene H, Wei, Minjie, Sun, Tao, Li, George, Liu, Shu Q, Li, Xinmin, Bhan, Ishir, Zhao, Qun, Thadhani, Ravi, Li, Yan Chun

“…Vitamin D inhibits renin expression and blocks the compensatory induction of renin associated with the use of renin-angiotensin system inhibitors. Here we test…”
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Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease by Tamez, Hector, MD, MPH, Zoccali, Carmine, MD, Packham, David, MD, Wenger, Julia, MPH, Bhan, Ishir, MD, MPH, Appelbaum, Evan, MD, MM, Sci, Pritchett, Yili, PhD, Chang, Yuchiao, PhD, Agarwal, Rajiv, MD, Wanner, Christoph, MD, Lloyd-Jones, Donald, MD, ScD, Cannata, Jorge, MD, Thompson, B. Taylor, MD, Andress, Dennis, MD, Zhang, Wuyan, PhD, Singh, Bhupinder, MD, Zehnder, Daniel, MD, Pachika, Ajay, MD, Manning, Warren J., MD, Shah, Amil, MD, Solomon, Scott D., MD, Thadhani, Ravi, MD, MPH

“…Background Left atrial enlargement, a sensitive integrator of left ventricular diastolic function, is associated with increased cardiovascular morbidity and…”
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Clinical Measures Identify Vitamin D Deficiency in Dialysis by Bhan, Ishir, Burnett-Bowie, Sherri-Ann M, Ye, Jun, Tonelli, Marcello, Thadhani, Ravi

“…Vitamin D deficiency (defined by serum levels of 25-hydroxyvitamin D) is common in patients with ESRD on hemodialysis, but risk factors are unknown. This study…”
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Nusinersen in Infants Who Initiate Treatment in a Presymptomatic Stage of Spinal Muscular Atrophy (SMA): Interim Efficacy and Safety Results From the Phase 2 NURTURE Study (S25.001) by De Vivo, Darryl C., Topaloglu, Haluk, Swoboda, Kathryn J., Bertini, Enrico, Hwu, Wuh-Liang, Crawford, Thomas O., Foster, Richard, Bhan, Ishir, Fradette, Stephanie, Farwell, Wildon, Reyna, Sandra P.

“…Abstract only…”
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