Search Results - "BETZ, CHRISTIAN"

Dupilumab (Dupixent®) tends to be an effective therapy for uncontrolled severe chronic rhinosinusitis with nasal polyps: real data of a single-centered, retrospective single-arm longitudinal study from a university hospital in Germany by Jansen, Florian, Becker, Benjamin, Eden, Jördis K., Breda, Philippe C., Hot, Amra, Oqueka, Tim, Betz, Christian S., Hoffmann, Anna S.

“…Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease, which is usually type 2-mediated in the western hemisphere,…”
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Next-generation sequencing identifies unexpected genotype-phenotype correlations in patients with retinitis pigmentosa by Birtel, Johannes, Gliem, Martin, Mangold, Elisabeth, Müller, Philipp L, Holz, Frank G, Neuhaus, Christine, Lenzner, Steffen, Zahnleiter, Diana, Betz, Christian, Eisenberger, Tobias, Bolz, Hanno J, Charbel Issa, Peter

“…Retinitis pigmentosa (RP) is an inherited degenerative disease causing severe retinal dystrophy and visual impairment mainly with onset in infancy or…”
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A noninvasive procedure for early-stage discrimination of malignant and precancerous vocal fold lesions based on laryngeal dynamics analysis by Unger, Jakob, Lohscheller, Jörg, Reiter, Maximilian, Eder, Katharina, Betz, Christian S, Schuster, Maria

“…About two thirds of laryngeal cancers originate at the vocal cords. Early-stage detection of malignant vocal fold alterations, including a discrimination of…”
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Endoscopic endonasal repair of complete bilateral choanal atresia in neonates by Ledderose, Georg J., Havel, Miriam, Ledderose, Carola, Betz, Christian S.

“…Reported success rates of endoscopic choanal atresia (CA) surgery vary substantially due to a high heterogeneity in and between study groups. Comprehensive…”
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Special tumor entities in the head and neck region: nasopharyngeal, salivary gland, and thyroid cancer by Zech, Henrike B, Betz, Christian S

“…At the meetings of the American Society of Clinical Oncology (ASCO) and the European Society for Medical Oncology (ESMO) in 2022, studies were presented which…”
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How much digitization do ENT curricula need? : Opportunities and limits from the perspective of students and teachers by Schmitz, Lisa, Betz, Christian S, Böttcher, Arne, Häußler, Sophia M, Praetorius, Mark

“…Digitalization has long been an integral part of students' everyday lives and increasingly also of their medical training. It seems to be an unwritten law that…”
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Lipidome Analysis of Oropharyngeal Tumor Tissues Using Nanosecond Infrared Laser (NIRL) Tissue Sampling and Subsequent Mass Spectrometry by Stadlhofer, Rupert, Moritz, Manuela, Fuh, Marceline M, Heeren, Jörg, Zech, Henrike, Clauditz, Till S, Schlüter, Hartmut, Betz, Christian S, Eggert, Dennis, Böttcher, Arne, Hahn, Jan

“…Ultrashort pulse infrared lasers can simultaneously sample and homogenize biological tissue using desorption by impulsive vibrational excitation (DIVE). With…”
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Special tumor entities in the head and neck region : Nasopharyngeal carcinoma, salivary gland, and thyroid cancer by Zech, Henrike B, Betz, Christian S

“…In recent years the number of studies on special tumor entities in the head and neck region has increased. During the 2021 meetings of the American Society of…”
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Reduced olfactory bulb volume accompanies olfactory dysfunction after mild SARS-CoV-2 infection by Petersen, Marvin, Becker, Benjamin, Schell, Maximilian, Mayer, Carola, Naegele, Felix L., Petersen, Elina, Twerenbold, Raphael, Thomalla, Götz, Cheng, Bastian, Betz, Christian, Hoffmann, Anna S.

“…Despite its high prevalence, the determinants of smelling impairment in COVID-19 remain not fully understood. In this work, we aimed to examine the association…”
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The “fascia taco” for nasal septum perforation closure—A retrospective Cohort study on success rates and patient reported outcomes by Bier, Johannes, Klingner, Alexandra, Stadlhofer, Rupert, Betz, Christian S., Böttcher, Arne

“…Objective Nasal septum perforation (NSP) is a common condition affecting ~1.2% of the general population and is still considered challenging to treat…”
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Decision-making in the treatment of chronic rhinosinusitis with nasal polyps in the era of biologics by Hoffmann, Anna S, Betz, Christian S, Böscke, Robert, Weber, Rainer K

“…Chronic rhinosinusitis is one of the most common chronic diseases in the population. Chronic rhinosinusitis with nasal polyps (CRSwNP) in adults is…”
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Phase III study of nivolumab alone or combined with ipilimumab as immunotherapy versus standard of care in resectable head and neck squamous cell carcinoma by Zech, Henrike B, Moeckelmann, Nikolaus, Boettcher, Arne, Muenscher, Adrian, Binder, Mascha, Vettorazzi, Eik, Bokemeyer, Carsten, Schafhausen, Philippe, Betz, Christian S, Busch, Chia-Jung

“…Locally advanced head and neck squamous cell carcinoma (LA-HNSCC) often requires postoperative chemoradiation with high risk of toxicity. Disease-free survival…”
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Tissue microarray analyses of the essential DNA repair factors ATM, DNA-PKcs and Ku80 in head and neck squamous cell carcinoma by Zech, Henrike Barbara, von Bargen, Clara, Oetting, Agnes, Möckelmann, Nikolaus, Möller-Koop, Christina, Witt, Melanie, Struve, Nina, Petersen, Cordula, Betz, Christian, Rothkamm, Kai, Münscher, Adrian, Clauditz, Till Sebastian, Rieckmann, Thorsten

“…Head and neck squamous cell carcinoma (HNSCC) negative for Human Papillomavirus (HPV) has remained a difficult to treat entity, whereas tumors positive for HPV…”
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Light Up the Tissue and Brighten Your Patients’ Odds by Witjes, Max J. H., Betz, Christian S., van Dam, Go M.

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Intraoperative assessment of laryngeal pathologies with optical coherence tomography integrated into a surgical microscope by Englhard, Anna S., Betz, Tom, Volgger, Veronika, Lankenau, Eva, Ledderose, Georg J., Stepp, Herbert, Homann, Christian, Betz, Christian S.

“…Objective Endoscopic examination followed by tissue biopsy is the gold standard in the evaluation of lesions of the upper aerodigestive tract. However, it can…”
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A deep intronic CLRN1 (USH3A) founder mutation generates an aberrant exon and underlies severe Usher syndrome on the Arabian Peninsula by Khan, Arif O., Becirovic, Elvir, Betz, Christian, Neuhaus, Christine, Altmüller, Janine, Maria Riedmayr, Lisa, Motameny, Susanne, Nürnberg, Gudrun, Nürnberg, Peter, Bolz, Hanno J.

“…Deafblindness is mostly due to Usher syndrome caused by recessive mutations in the known genes. Mutation-negative patients therefore either have distinct…”
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Evaluation of optical coherence tomography to discriminate lesions of the upper aerodigestive tract by Volgger, Veronika, Stepp, Herbert, Ihrler, Stephan, Kraft, Marcel, Leunig, Andreas, Patel, Parag M., Susarla, Malavika, Jackson, Kathleen, Betz, Christian S.

“…Background This study evaluated the capability of optical coherence tomography (OCT) to differentiate premalignant and early malignant lesions of the upper…”
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Rational surgical neck management in total laryngectomy for advanced stage laryngeal squamous cell carcinomas by Böttcher, Arne, Betz, Christian S., Bartels, Stefan, Schoennagel, Bjoern, Münscher, Adrian, Bußmann, Lara, Busch, Chia-Jung, Knopke, Steffen, Bibiza, Eric, Möckelmann, Nikolaus

“…Purpose Controversies exist in regard to surgical neck management in total laryngectomies (TL). International guidelines do not sufficiently discriminate neck…”
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Value of fluorescence endoscopy for the early diagnosis of laryngeal cancer and its precursor lesions by Kraft, Marcel, Betz, Christian Stephan, Leunig, Andreas, Arens, Christoph

“…Background Fluorescence endoscopy is used for the early detection and delineation of laryngeal cancer and its precursor lesions. No systematic review of these…”
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A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells by Köcher, Sabrina, Zech, Henrike Barbara, Krug, Leonie, Gatzemeier, Fruzsina, Christiansen, Sabrina, Meyer, Felix, Rietow, Ruth, Struve, Nina, Mansour, Wael Yassin, Kriegs, Malte, Petersen, Cordula, Betz, Christian, Rothkamm, Kai, Rieckmann, Thorsten

“…Patients with human papillomavirus-positive squamous cell carcinoma of the head and neck (HPV+ HNSCC) have a favorable prognosis compared to those with…”
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