Search Results - "BETUL TEKINER-GULBAS"

Oxidative stress in carcinogenesis: new synthetic compounds with dual effects upon free radicals and cancer by Tekiner-Gulbas, Betul, Westwell, Andrew D, Suzen, Sibel

“…DNA mutation is a very important step in carcinogenesis and elevated levels of oxidative DNA damage have been monitored in a variety of tumors. The discovery…”
Get more information

Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents by Ertan, Tugba, Yildiz, Ilkay, Tekiner-Gulbas, Betul, Bolelli, Kayhan, Temiz-Arpaci, Ozlem, Ozkan, Semiha, Kaynak, Fatma, Yalcin, Ismail, Aki, Esin

“…A new series of 5(or 6)-nitro/amino-2-(substituted phenyl/benzyl)benzoxazole derivatives ( 1a– 1m, 2a– 2l) were synthesized and evaluated for antibacterial and…”
Get full text

Vibrational spectroscopic studies and ab initio calculations of 5-methyl-2-( p-methylaminophenyl)benzoxazole by Ambujakshan, K.R., Madhavan, V.S., Varghese, Hema Tresa, Panicker, C. Yohannan, Temiz-Arpaci, Ozlem, Tekiner-Gulbas, Betul, Yildiz, Ilkay

“…FT-IR spectra of 5-methyl-2-( p-methylaminophenyl)benzoxazole was recorded and analysed. The vibrational frequencies of the compound have been computed using…”
Get full text

Synthesis and Antimicrobial Activity of New 2-[p-Substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles by Yildiz-Oren, Ilkay, Tekiner-Gulbas, Betul, Yalcin, Ismail, Temiz-Arpaci, Ozlem, Akı-Sener, Esin, Altanlar, Nurten

“…A series of 23 new 2‐[p‐substituted‐benzyl]‐5‐[p‐substituted‐phenyl/benzyl‐carbonylamino]benzoxazole derivatives has been synthesized by reacting…”
Get full text

Induction of Apoptosis and Necrosis by Resistance Modifiers Benzazoles and Benzoxazines on Tumour Cell Line Mouse Lymphoma L5718 Mdr+cells by ANDRAS VARGA, ESIN AKI-SENER, ISMAIL YALCIN, OZLEM TEMIZ-ARPACI, BETUL TEKINER-GULBAS, GEORGY CHEREPNEV, JOSEPH MOLNAR

“…Eighteen new fused heterocyclic compounds of benzazoles and benzoxazines were investigated for induction and inhibition of apoptosis on tumor cells (L5718,…”
Get full text

Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization by Suzen, Sibel, Tekiner-Gulbas, Betul, Shirinzadeh, Hanif, Uslu, Duysal, Gurer-Orhan, Hande, Gumustas, Mehmet, Ozkan, Sibel Aysil

“…Melatonin (MLT) is a strong free-radical scavenger, which protects the body from the effects of oxidants. In recent years, MLT have been described resulting in…”
Get more information

Synthesis and in vitro antimicrobial activity of new 2-[ p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles by Tekiner-Gulbas, Betul, Temiz-Arpaci, Ozlem, Yildiz, Ilkay, Altanlar, Nurten

“…Some new 2-(benzyl/ p-chlorobenzyl)-5-[(substituted-thienyl/phenyl/phenylthiomethyl/benzyl)carbonylamino]benzoxazole derivatives have been synthesized by…”
Get full text

Some benzoxazoles and benzimidazoles as DNA topoisomerase I and II inhibitors by Oksuzoglu, Emine, Tekiner-Gulbas, Betul, Alper, Sabiha, Temiz-Arpaci, Ozlem, Ertan, Tugba, Yildiz, Ilkay, Diril, Nuran, Sener-Aki, Esin, Yalcin, Ismail

“…Some novel fused heterocyclic compounds of 2, 5-disubstituted-benzoxazole and benzimidazole derivatives, which were previously synthesized by our group, were…”
Get more information

Benzothiazole derivatives as human DNA topoisomerase IIα inhibitors by Kaplan-Ozen, Cigdem, Tekiner-Gulbas, Betul, Foto, Egemen, Yildiz, Ilkay, Diril, Nuran, Aki, Esin, Yalcin, Ismail

“…Benzothiazole derivatives resembling the structure of DNA purine bases were tested to determine their topoisomerase inhibition activities. Based on DNA…”
Get full text

Vibrational spectroscopic studies and ab initio calculations of 5-methyl-2-( p-fluorophenyl)benzoxazole by Anto, P.L., Panicker, C. Yohannan, Varghese, Hema Tresa, Philip, Daizy, Temiz-Arpaci, Ozlem, Tekiner-Gulbas, Betul, Yildiz, Ilkay

“…FT-Raman and FT-IR spectra of 5-methyl-2-( p-fluorophenyl)benzoxazole were recorded and analysed. The vibrational frequencies of the compound have been…”
Get full text

Benzoxazines as new human topoisomerase I inhibitors and potential poisons by Foto, Egemen, Özen, Çigdem, Zilifdar, Fatma, Tekiner-Gülbaş, Betül, Yıldız, İlkay, Akı-Yalçın, Esin, Diril, Nuran, Yalçın, İsmail

“…Background The numbers of topoisomerase I targeted drugs on the market are very limited although they are used clinically for treatment of solid tumors. Hence,…”
Get full text

A study on the genotoxic activities of some new benzoxazoles by Oksuzoglu, Emine, Temiz-Arpaci, Ozlem, Tekiner-Gulbas, Betul, Eroglu, Hatice, Sen, Gulseren, Alper, Sabiha, Yildiz, Ilkay, Diril, Nuran, Aki-Sener, Esin, Yalcin, Ismail

“…The Bacillus subtilis rec assay has been specially developed to detect DNA-damaging potential in chemicals, with the rationale based on the relative difference…”
Get full text

3D-QSAR analysis on benzazole derivatives as eukaryotic topoisomerase II inhibitors by using comparative molecular field analysis method by Temiz-Arpaci, Ozlem, Tekiner-Gulbas, Betul, Yildiz, Ilkay, Aki-Sener, Esin, Yalcin, Ismail

“…3D-QSAR analysis has been performed on a series of previously synthesized benzoxazole, benzimidazole, and oxazolo(4,5-b)pyridine derivatives, which are…”
Get full text

Synthesis of Novel Pyrazolo[5,1-b][1,3]benzothiazoles: A New Pericyclic Pathway by Hajós, György, Tekiner-Gulbas, Bet殕, Fil, L zl, 軾nes Vask, Gy嗜gyv屍, Egyed, Orsolya, Yal絞n, Ismail, Aki-Sener, Esin, Riedl, Zsuzsanna

Get full text

DFT calculations of some antimicrobial active 3,4-dihydro-1,4-benzoxazin-3-one derivatives by GÜLBAŞ, Betül P., Tekiner, ÖREN, İlkay, Yıldız

“…Bu çalışmada, beş adet antimikrobiyal etkili etil 3,4-dihidro-6-ve/veya 7-sübstitüe-3-okso-2H-1,4-benzoksazin-2-asetat türevleri DFT ile Becke3LYP/6-31G(d,p) ,…”
Get full text

Bazı antibakteriyal etkili 5-sübstitüe karbonilamino- 2-(p-sübstitüebenzil)benzoksazol türevlerinin staphylococcus aureus’a karşı kantitatif yapı-etki ilişkileri analizleri : quantitative structure-ac by GÜLBAŞ, Betül P. Tekiner

Get full text

DFT CALCULATIONS OF SOME ANTIMICROBIAL ACTIVE 3,4-DIHYDRO-l,4-BENZOXAZIN-3-ONE DERIVATIVES : BAZI ANTİMİKROBİYAL ETKİLİ 3,4-DİHİDRO-l,4-BENZOKSAZİN-3-ON TÜREVLERİNİN DFT HESAPLAMALARI by ÖREN, İlkay Yıldız, GÜLBAŞ, Betül P. Tekiner

Get full text