Search Results - "BERTRAND, Luc"

Metformin: From Mechanisms of Action to Therapies by Foretz, Marc, Guigas, Bruno, Bertrand, Luc, Pollak, Michael, Viollet, Benoit

“…Metformin is currently the first-line drug treatment for type 2 diabetes. Besides its glucose-lowering effect, there is interest in actions of the drug of…”
Get full text

AMP-activated protein kinase: A remarkable contributor to preserve a healthy heart against ROS injury by Marino, Alice, Hausenloy, Derek J., Andreadou, Ioanna, Horman, Sandrine, Bertrand, Luc, Beauloye, Christophe

“…Heart failure is one of the leading causes of death and disability worldwide. Left ventricle remodeling, fibrosis, and ischemia/reperfusion injury all…”
Get full text

AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation by Daskalopoulos, Evangelos P, Dufeys, Cécile, Bertrand, Luc, Beauloye, Christophe, Horman, Sandrine

“…Abstract Fibrosis is a general term encompassing a plethora of pathologies that span all systems and is marked by increased deposition of collagen. Injury of…”
Get full text

Effect of hyperglycaemia and diabetes on acute myocardial ischaemia–reperfusion injury and cardioprotection by ischaemic conditioning protocols by Penna, Claudia, Andreadou, Ioanna, Aragno, Manuela, Beauloye, Christophe, Bertrand, Luc, Lazou, Antigone, Falcão‐Pires, Ines, Bell, Robert, Zuurbier, Coert J., Pagliaro, Pasquale, Hausenloy, Derek J.

“…Diabetic patients are at increased risk of developing coronary artery disease and experience worse clinical outcomes following acute myocardial infarction…”
Get full text

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation by Gélinas, Roselle, Mailleux, Florence, Dontaine, Justine, Bultot, Laurent, Demeulder, Bénédicte, Ginion, Audrey, Daskalopoulos, Evangelos P., Esfahani, Hrag, Dubois-Deruy, Emilie, Lauzier, Benjamin, Gauthier, Chantal, Olson, Aaron K., Bouchard, Bertrand, Des Rosiers, Christine, Viollet, Benoit, Sakamoto, Kei, Balligand, Jean-Luc, Vanoverschelde, Jean-Louis, Beauloye, Christophe, Horman, Sandrine, Bertrand, Luc

“…AMP-activated protein kinase (AMPK) has been shown to inhibit cardiac hypertrophy. Here, we show that submaximal AMPK activation blocks cardiomyocyte…”
Get full text

SUDS, LID, BMPs, WSUD and more - The evolution and application of terminology surrounding urban drainage by Fletcher, Tim D., Shuster, William, Hunt, William F., Ashley, Richard, Butler, David, Arthur, Scott, Trowsdale, Sam, Barraud, Sylvie, Semadeni-Davies, Annette, Bertrand-Krajewski, Jean-Luc, Mikkelsen, Peter Steen, Rivard, Gilles, Uhl, Mathias, Dagenais, Danielle, Viklander, Maria

“…The management of urban stormwater has become increasingly complex over recent decades. Consequently, terminology describing the principles and practices of…”
Get full text

Cardiac metabolism as a driver and therapeutic target of myocardial infarction by Zuurbier, Coert J., Bertrand, Luc, Beauloye, Christoph R., Andreadou, Ioanna, Ruiz‐Meana, Marisol, Jespersen, Nichlas R., Kula‐Alwar, Duvaraka, Prag, Hiran A., Eric Botker, Hans, Dambrova, Maija, Montessuit, Christophe, Kaambre, Tuuli, Liepinsh, Edgars, Brookes, Paul S., Krieg, Thomas

“…Reducing infarct size during a cardiac ischaemic‐reperfusion episode is still of paramount importance, because the extension of myocardial necrosis is an…”
Get full text

Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK by Angin, Yeliz, Beauloye, Christophe, Horman, Sandrine, Bertrand, Luc

“…This chapter summarizes AMPK function in the regulation of substrate and energy metabolism with the main emphasis on carbohydrate and lipid metabolism, protein…”
Get more information

Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function by Zacchigna, Serena, Paldino, Alessia, Falcão-Pires, Inês, Daskalopoulos, Evangelos P, Dal Ferro, Matteo, Vodret, Simone, Lesizza, Pierluigi, Cannatà, Antonio, Miranda-Silva, Daniela, Lourenço, André P, Pinamonti, Bruno, Sinagra, Gianfranco, Weinberger, Florian, Eschenhagen, Thomas, Carrier, Lucie, Kehat, Izhak, Tocchetti, Carlo G, Russo, Michele, Ghigo, Alessandra, Cimino, James, Hirsch, Emilio, Dawson, Dana, Ciccarelli, Michele, Oliveti, Marco, Linke, Wolfgang A, Cuijpers, Ilona, Heymans, Stephane, Hamdani, Nazha, de Boer, Martine, Duncker, Dirk J, Kuster, Diederik, van der Velden, Jolanda, Beauloye, Christophe, Bertrand, Luc, Mayr, Manuel, Giacca, Mauro, Leuschner, Florian, Backs, Johannes, Thum, Thomas

“…Abstract Echocardiography is a reliable and reproducible method to assess non-invasively cardiac function in clinical and experimental research. Significant…”
Get full text

End-user perspective of low-cost sensors for urban stormwater monitoring: a review by Zhu, Qingchuan, Cherqui, Frédéric, Bertrand-Krajewski, Jean-Luc

“…The large-scale deployment of low-cost monitoring systems has the potential to revolutionize the field of urban hydrology monitoring, bringing improved urban…”
Get full text

Targeting the HIV-infected brain to improve ischemic stroke outcome by Bertrand, Luc, Méroth, Fannie, Tournebize, Marie, Leda, Ana Rachel, Sun, Enze, Toborek, Michal

“…HIV-associated cerebrovascular events remain highly prevalent even in the current era of antiretroviral therapy (ART). We hypothesize that low-level HIV…”
Get full text

Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues by Maes, Arne, Pestiaux, Camille, Marino, Alice, Balcaen, Tim, Leyssens, Lisa, Vangrunderbeeck, Sarah, Pyka, Grzegorz, De Borggraeve, Wim M., Bertrand, Luc, Beauloye, Christophe, Horman, Sandrine, Wevers, Martine, Kerckhofs, Greet

“…Biological tissues comprise a spatially complex structure, composition and organization at the microscale, named the microstructure. Given the close…”
Get full text

Selective Disruption of the Blood–Brain Barrier by Zika Virus by Leda, Ana Rachel, Bertrand, Luc, Andras, Ibolya Edit, El-Hage, Nazira, Nair, Madhavan, Toborek, Michal

“…The blood–brain barrier (BBB) selectively regulates the cellular exchange of macromolecules between the circulation and the central nervous system (CNS). Here,…”
Get full text

Solving the Blood-Brain Barrier Challenge for the Effective Treatment of HIV Replication in the Central Nervous System by Bertrand, Luc, Nair, Madhavan, Toborek, Michal

“…Recent decades mark a great progress in the treatment of HIV infection. What was once a deadly disease is now a chronic infection. However, HIV-infected…”
Get more information

Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs: novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart by Tocchetti, Carlo Gabriele, Ameri, Pietro, de Boer, Rudolf A, D’Alessandra, Yuri, Russo, Michele, Sorriento, Daniela, Ciccarelli, Michele, Kiss, Bernadett, Bertrand, Luc, Dawson, Dana, Falcao-Pires, Ines, Giacca, Mauro, Hamdani, Nazha, Linke, Wolfgang A, Mayr, Manuel, van der Velden, Jolanda, Zacchigna, Serena, Ghigo, Alessandra, Hirsch, Emilio, Lyon, Alexander R, Görbe, Anikó, Ferdinandy, Péter, Madonna, Rosalinda, Heymans, Stephane, Thum, Thomas

“…Abstract In western countries, cardiovascular (CV) disease and cancer are the leading causes of death in the ageing population. Recent epidemiological data…”
Get full text

Diabetic Cardiomyopathy and Ischemic Heart Disease: Prevention and Therapy by Exercise and Conditioning by Crisafulli, Antonio, Pagliaro, Pasquale, Roberto, Silvana, Cugusi, Lucia, Mercuro, Giuseppe, Lazou, Antigone, Beauloye, Christophe, Bertrand, Luc, Hausenloy, Derek J, Aragno, Manuela, Penna, Claudia

“…Metabolic syndrome, diabetes, and ischemic heart disease are among the leading causes of death and disability in Western countries. Diabetic cardiomyopathy is…”
Get full text

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders by Viollet, Benoit, Foretz, Marc, Guigas, Bruno, Horman, Sandrine, Dentin, Renaud, Bertrand, Luc, Hue, Louis, Andreelli, Fabrizio

“…It is now becoming evident that the liver has an important role in the control of whole body metabolism of energy nutrients. In this review, we focus on recent…”
Get full text

New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans by Ferté, Laura, Marino, Alice, Battault, Sylvain, Bultot, Laurent, Van Steenbergen, Anne, Bol, Anne, Cumps, Julien, Ginion, Audrey, Koepsell, Hermann, Dumoutier, Laure, Hue, Louis, Horman, Sandrine, Bertrand, Luc, Beauloye, Christophe

“…Although sodium glucose cotransporter 1 (SGLT1) has been identified as one of the major SGLT isoforms expressed in the heart, its exact role remains elusive…”
Get more information

Sex Differences of the Diabetic Heart by Fourny, Natacha, Beauloye, Christophe, Bernard, Monique, Horman, Sandrine, Desrois, Martine, Bertrand, Luc

“…Type 2 diabetes is a chronic disease associated with micro- and macro-vascular complications, including myocardial ischemia, and also with a specific and…”
Get full text

Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals by Rodriguez, Julie, Neyrinck, Audrey M, Van Kerckhoven, Maxime, Gianfrancesco, Marco A, Renguet, Edith, Bertrand, Luc, Cani, Patrice D, Lanthier, Nicolas, Cnop, Miriam, Paquot, Nicolas, Thissen, Jean-Paul, Bindels, Laure B, Delzenne, Nathalie M

“…Dietary interventions targeting the gut microbiota have been proposed as innovative strategies to improve obesity-associated metabolic disorders. Increasing…”
Get full text