Search Results - "BERTRAM, John S"

Connexins as targets for cancer chemoprevention and chemotherapy by King, Timothy J., Bertram, John S.

“…Cells within a tissue continuously interact to coordinate normal tissue functions and maintain homeostasis. Gap junctional communication (GJC), mediated by the…”
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Cancer prevention by retinoids and carotenoids: Independent action on a common target by Bertram, John S., Vine, Alex L.

“…Virtually all human tumors are deficient in gap junctional communication (GJC) and the restoration of GJC by forced expression of connexins reduces indices of…”
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Phase II Randomized Clinical Trial of Lycopene Supplementation before Radical Prostatectomy by KUCUK, Omer, SARKAR, Fazlul H, CRISSMAN, John D, PONTES, Edson J, WOOD, David P, SAKR, Wael, DJURIC, Zora, POLLAK, Michael N, KHACHIK, Fred, LI, Yi-Wei, BANERJEE, Mousumi, GRIGNON, David, BERTRAM, John S

“…An inverse association has been observed between dietary intake of lycopene and the risk of prostate cancer. We investigated the effects of lycopene…”
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Upregulation of connexin 43 protein expression and increased gap junctional communication by water soluble disodium disuccinate astaxanthin derivatives by Hix, Laura M, Lockwood, Samuel F, Bertram, John S

“…Carotenoids are plant pigments whose consumption is associated with lower cancer rates in humans. Studies in experimental animal and cell systems have…”
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Inhibition of chemically-induced neoplastic transformation by a novel tetrasodium diphosphate astaxanthin derivative by Hix, Laura M., Frey, Dean A., McLaws, Mark D., Østerlie, Marianne, Lockwood, Samuel F., Bertram, John S.

“…Carotenoids have been implicated in numerous epidemiological studies as being protective against cancer at many sites, and their chemopreventive properties…”
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The molecular biology of cancer by Bertram, John S

“…The process by which normal cells become progressively transformed to malignancy is now known to require the sequential acquisition of mutations which arise as…”
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Transcriptional regulation of connexin 43 expression by retinoids and carotenoids: Similarities and differences by Vine, Alex L., Leung, Yee M., Bertram, John S.

“…Gap junctions, connexons, are formed by assembly of trans‐membrane connexin proteins and have multiple functions including the coordination of cell responses…”
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Effects of lycopene supplementation in patients with localized prostate cancer by Kucuk, Omer, Sarkar, Fazlul H, Djuric, Zora, Sakr, Wael, Pollak, Michael N, Khachik, Fred, Banerjee, Mousumi, Bertram, John S, Wood, Jr, David P

“…Epidemiological studies have shown an inverse association between dietary intake of lycopene and prostate cancer risk. We conducted a clinical trial to…”
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Carotenoids and gene regulation by Bertram, John S.

“…Consumption of dietary carotenoids, plant pigments found in green, yellow, and orange fruits and vegetables, has been linked to decreased risk of cancer…”
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Metabolites of dietary carotenoids as potential cancer preventive agents by King, T. J., Khachik, F., Bortkiewicz, Hanna, Fukushima, L. H., Morioka, S., Bertram, John S.

“…Abstract…”
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Induction of connexin 43 by carotenoids: functional consequences by Bertram, John S.

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Bioactive carotenoids: potent antioxidants and regulators of gene expression by Hix, Laura M, Lockwood, Samuel F, Bertram, John S

“…Carotenoids are plant pigments, some of which act as a vital source of vitamin A to all animals, that appear to have additional benefits to primates. They are…”
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Dietary carotenoids inhibit neoplastic transformation and modulate gene expression in mouse and human cells by Bertram, JS, Bortkiewicz, H

“…Many epidemiologic studies have associated the consumption of diets rich in fruit and green and yellow vegetables with a decreased risk of cancer. Of the many…”
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Cancer chemoprevention by connexins by Vine, Alex L, Bertram, John S

“…Gap junctions, or connexons, are formed by connexin proteins and connect most cells in the body to form water-filled channels directly linking the cytoplasm…”
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Upregulation of connexin 43 by retinoids but not by non-provitamin A carotenoids requires RARs by Vine, A.L, Bertram, J.S

“…Expression of connexin 43 (Cx43) is correlated with reduced indexes of neoplasia and is upregulated by cancer-preventive retinoids and carotenoids in…”
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Carotenoids up-regulate connexin43 gene expression independent of their provitamin A or antioxidant properties by LI-XIN ZHANG, COONEY, R. V, BERTRAM, J. S

“…Epidemiological evidence and studies in whole animals and cell culture have indicated that carotenoids have cancer chemopreventive action. In mouse C3H10T1/2…”
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Inducible expression of the gap junction protein connexin43 decreases the neoplastic potential of HT-1080 human fibrosarcoma cells in vitro and in vivo by King, Timothy J., Fukushima, Laurie H., Yasui, Yutaka, Lampe, Paul D., Bertram, John S.

“…Numerous studies have demonstrated a correlation between dysregulation/loss of connexin expression or gap junction intercellular communication (GJIC) function…”
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Diverse carotenoids protect against chemically induced neoplastic transformation by Bertram, J S, Pung, A, Churley, M, Kappock, 4th, T J, Wilkins, L R, Cooney, R V

“…The ability of diverse carotenoid to inhibit methylcholanthrene-induced transformation of 10T1/2 cells has been investigated. When delivered using…”
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Lycopene in the treatment of prostate cancer by Kucuk, Omer, Sarkar, Fazlul H., Sakr, Wael, Khachik, Fred, Djuric, Zora, Banerjee, Mousumi, Pollak, Michael N., Bertram, John S., Wood, David P.

“…Dietary intake of lycopene is associated with reduced risk of prostate cancer (PCa). We conducted a clinical trial in men with prostate cancer to investigate…”
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The chemoprevention of cancer by dietary carotenoids: Studies in mouse and human cells by Bertram, John S.

“…Abstract…”
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