Search Results - "BERTOLINI, D. R"

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors by Bertolini, Donald R, Nedwin, Glenn E, Bringman, Timothy S, Smith, Donna D, Mundy, Gregory R

“…When leukocytes are exposed to mitogens or antigens in vitro, they release bone-resorbing activity into the culture supernatants which can be detected by…”
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Cytokine suppressive anti-inflammatory compounds inhibit bone resorption in vitro by Votta, B J, Bertolini, D R

“…Data from several laboratories suggest a role for a variety of cytokines in the process of bone resorption. SK&F 86002…”
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Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells by Garrett, I R, Durie, B G, Nedwin, G E, Gillespie, A, Bringman, T, Sabatini, M, Bertolini, D R, Mundy, G R

“…Myeloma cells destroy bone by producing an osteoclast-stimulating factor that has chemical and biological characteristics similar to the bone-resorbing…”
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Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells by RODAN, S. B, INSOGNA, K. L, VIGNERY, A. M.-C, STEWART, A. F, BROADUS, A. E, DSOUZA, S. M, BERTOLINI, D. R, MUNDY, G. R, RODAN, G. A

“…The culture media of three cell lines, a human prostate carcinoma (PC3), a rat Leydig cell tumor (Rice-500), and a rat carcinosarcoma (WRC-256), that were…”
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Production of 1,25-dihydroxyvitamin D3 by human T cell lymphotrophic virus-I―transformed lymphocytes by FETCHICK, D. A, BERTOLINI, D. R, SARIN, P. S, WEINTRAUB, S. T, MUNDY, G. R, DUNN, J. F

“…The human T cell lymphotrophic virus type I (HTLV-I) has recently been identified in a T cell lymphoma associated with hypercalcemia and increased bone…”
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Biotinylated parathyroid hormone as a probe for the parathyroid hormone receptor. Structure-function analysis and detection of specific binding to cultured bone cells by flow cytometry by NEWMAN, W, BEALL, L. D, LEVINE, M. A, CONE, J. L, RANDHAWA, Z. I, BERTOLINI, D. R

“…The synthetic bovine parathyroid hormone (PTH) analog (Nle8, Nle18, Tyr34) bovine PTH(1-34)amide (bPTH(1-34)amide) was reacted with biotinyl-epsilon…”
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Modulation of TGF-beta type 1 receptor: flow cytometric detection with biotinylated TGF-beta by Newman, W, Beall, L D, Bertolini, D R, Cone, J L

“…Transforming growth factor beta type 1 (TGF-beta 1) was reacted with NHS-biotin to yield a derivative of TGF-beta 1 which was biotinylated on lysine residues…”
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Regulation of murine mononuclear phagocyte inflammatory products by macrophage colony-stimulating factor. Lack of IL-1 and prostaglandin E2 production and generation of a specific IL-1 inhibitor by Strassmann, G, Bertolini, DR, Kerby, SB, Fong, M

“…The influence of macrophage (M)-CSF on the production of inflammatory mediators has been examined in murine peritoneal macrophages. Cultures of macrophages…”
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Bone destruction and hypercalcemia in plasma cell myeloma by Mundy, G R, Bertolini, D R

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Mechanisms of paraneoplastic syndromes of colon-26: involvement of interleukin 6 in hypercalcemia by Strassmann, G, Jacob, C O, Fong, M, Bertolini, D R

“…The precise mechanisms responsible for increased calcium levels in patients with cancer are not fully understood. In a recent study, the participation of…”
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Inhibition of immune reactions in vivo by liposome associated transforming growth factor (TGF) type β1 by STRASSMANN, G., BERTOUNI, D. R., EIDELMAN, O.

“…SUMMARY In view of its potent inhibitory capacity on immune cells in culture, we wished to determine the ability of transforming growth factor (TGF) β1 to…”
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Inhibition of immune reactions in vivo by liposome associated transforming growth factor (TGF) type beta 1 by Strassmann, G, Bertolini, D R, Eidelman, O

“…In view of its potent inhibitory capacity on immune cells in culture, we wished to determine the ability of transforming growth factor (TGF) beta 1 to…”
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Biotinylated parathyroid hormone as a probe for the parathyroid hormone receptor by Newman, W, Beall, L D, Levine, M A, Cone, J L, Randhawa, Z I, Bertolini, D R

“…The synthetic bovine parathyroid hormone (PTH) analog (Nle8, Nle18, Tyr34) bovine PTH(1-34)amide (bPTH(1-34)amide) was reacted with biotinyl-ε aminocaproic…”
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Protease-insensitive sea urchin embryo cell adhesions become protease sensitive in the presence of azide or cytochalasin B by Bertolini, D R, Watanabe, M, Turner, Jr, R S

“…To understand the nature of the cell adhesions that must be modified during sea urchin embryo primary mesenchyme formation, we are studying the adhesive…”
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17β‐Hydroxysteroid Dehydrogenases in Human Bone Cells by Dong, Yu, Qiu, Qing Qing, Debear, Joanna, Lathrop, William F., Bertolini, Donald R., Tamburini, Paul P.

“…Interconversion of estrogens by osteoblasts may play a role in regulating bone mass. As a first step toward exploring this possibility, we investigated the…”
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Characterization of Bone Structure in Leptin Receptor‐Deficient Zucker (fa/fa) Rats by Tamasi, Joseph A, Arey, Brian J, Bertolini, Donald R, Feyen, Jean HM

“…To investigate the role of leptin in bone formation, the skeleton of the obese female leptin receptor‐deficient Zucker rat was examined using pQCT, μCT, and…”
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Changes in the nature of the cell adhesions of the sea urchin embryo by Watanabe, Michiko, Bertolini, Donald R., Kew, David, Turner, Robert S.

“…Reaggregation of cells from 16-cell, 100-cell, 200-cell, hatched-blastula, and gastrula stage sea urchin embryos is essentially equivalent in the absence of…”
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17Beta-hydroxysteroid dehydrogenases in human bone cells by Dong, Y, Qiu, Q Q, Debear, J, Lathrop, W F, Bertolini, D R, Tamburini, P P

“…Interconversion of estrogens by osteoblasts may play a role in regulating bone mass. As a first step toward exploring this possibility, we investigated the…”
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Interleukin 6 production in fetal rat long bone cultures is correlated with PGE2 release and does not correlate with the extent of bone resorption by Bertolini, D R, Votta, B, Hoffman, S, Strassmann, G

“…Reports from several laboratories have suggested that interleukin 6 (IL-6) may play a role in the process of bone resorption. We have extended these studies by…”
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Differential activity of granulocyte-macrophage and macrophage colony stimulating factors on bone resorption in fetal rat long bone organ cultures by Bertolini, D R, Strassmann, G

“…In this study, the ability of recombinant human macrophage (M) and murine granulocyte-macrophage (GM) colony stimulating factor (CSF) to affect both basal and…”
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