Search Results - "BERTHOLET, Vincent"

Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes by GILLET, Jean-Pierre, EFFERTH, Thomas, STEINBACH, Daniel, HAMELS, Jacques, DE LONGUEVILLE, Francoise, BERTHOLET, Vincent, REMACLE, José

“…Different mechanisms of drug resistance, including ATP-binding cassette (ABC) transporters, are responsible for treatment failure of tumors. We developed a…”
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ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia by STEINBACH, Daniel, GILLET, Jean-Pierre, SAUERBREY, Axel, GRUHN, Bernd, DAWCZYNSKI, Kristin, BERTHOLET, Vincent, DE LONGUEVILLE, Francoise, ZINTL, Felix, REMADE, Jose, EFFERTH, Thomas

“…Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by…”
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Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays by Pascal, Thierry, Debacq-Chainiaux, Florence, Chrétien, Aline, Bastin, Coralie, Dabée, Anne-France, Bertholet, Vincent, Remacle, José, Toussaint, Olivier

“…Human diploid fibroblasts (HDFs) exposed to subcytotoxic stress display many features of senescence. Using differential display RT-PCR, gene expression of HDFs…”
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Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia by Efferth, Thomas, Gillet, Jean-Pierre, Sauerbrey, Axel, Zintl, Felix, Bertholet, Vincent, de Longueville, Françoise, Remacle, Jose, Steinbach, Daniel

“…A major issue in the treatment of T-cell acute lymphoblastic leukemia (T-ALL) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by…”
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Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray by de Longueville, Françoise, Surry, Dominic, Meneses-Lorente, Georgina, Bertholet, Vincent, Talbot, Valérie, Evrard, Stephanie, Chandelier, Nathalie, Pike, Andrew, Worboys, Phil, Rasson, Jean-Paul, Le Bourdellès, Béatrice, Remacle, José

“…DNA microarrays are useful tools to study changes of gene expression in response to a treatment with drugs. Here, we describe the optimization of conditions…”
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Robustness evaluation of weak anion exchange chromatography method for the purity analysis of therapeutic oligonucleotides by Nercessian, Lara, Ozturk, Dilhan, Butré, Claire I., Bertholet, Vincent, Patiny, Sébastien, Mouvet, Damien, Delobel, Arnaud

“…•Method optimization for separation of oligonucleotide impurities in a QC environment.•High-organic mobile phase ensures maximal resolution in weak anion…”
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An Evaluation of a Low-Density DNA Microarray Using Cytochrome P450 Inducers by Meneses-Lorente, Georgina, de Longueville, Françoise, Dos Santos-Mendes, Sofia, Bonnert, Timothy P, Jack, Andrew, Evrard, Stéphanie, Bertholet, Vincent, Pike, Andrew, Scott-Stevens, Paul, Remacle, José, Sohal, Bindi

“…The aim of this study was to validate a low-density DNA microarray “Rat HepatoChip”, which contains 59 genes from a range of potential toxic markers and drug…”
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Microarray Expression Profiling of ABC Transporters in Human Breast Cancer by Gillet, J-P, Schneider, J, Bertholet, V, De Longueville, F, Remacle, J, Efferth, T

“…The ATP-binding cassette (ABC) transporters are highly conserved genes involved in the translocation of molecules through biological membranes. Several of them…”
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The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies by Shi, Leming, Jones, Wendell D, Jensen, Roderick V, Harris, Stephen C, Perkins, Roger G, Goodsaid, Federico M, Guo, Lei, Croner, Lisa J, Boysen, Cecilie, Fang, Hong, Qian, Feng, Amur, Shashi, Bao, Wenjun, Barbacioru, Catalin C, Bertholet, Vincent, Cao, Xiaoxi Megan, Chu, Tzu-Ming, Collins, Patrick J, Fan, Xiao-Hui, Frueh, Felix W, Fuscoe, James C, Guo, Xu, Han, Jing, Herman, Damir, Hong, Huixiao, Kawasaki, Ernest S, Li, Quan-Zhen, Luo, Yuling, Ma, Yunqing, Mei, Nan, Peterson, Ron L, Puri, Raj K, Shippy, Richard, Su, Zhenqiang, Sun, Yongming Andrew, Sun, Hongmei, Thorn, Brett, Turpaz, Yaron, Wang, Charles, Wang, Sue Jane, Warrington, Janet A, Willey, James C, Wu, Jie, Xie, Qian, Zhang, Liang, Zhang, Lu, Zhong, Sheng, Wolfinger, Russell D, Tong, Weida

“…Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of…”
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Evaluation of drug transporters' significance for multidrug resistance in head and neck squamous cell carcinoma by Theile, Dirk, Ketabi-Kiyanvash, Nahal, Herold-Mende, Christel, Dyckhoff, Gerhardt, Efferth, Thomas, Bertholet, Vincent, Haefeli, Walter Emil, Weiss, Johanna

“…Background. Multidrug resistance (MDR) hampers chemotherapy in head and neck squamous cell carcinoma (HNSCC). There is little information about MDR mediating…”
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CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes by Vankoningsloo, Sébastien, Pauw, Aurélia De, Houbion, Andrée, Tejerina, Silvia, Demazy, Catherine, Longueville, Françoise de, Bertholet, Vincent, Renard, Patricia, Remacle, José, Holvoet, Paul, Raes, Martine, Arnould, Thierry

“…Several mitochondrial pathologies are characterized by lipid redistribution and microvesicular cell phenotypes resulting from triglyceride accumulation in…”
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Use of a Low-Density Microarray for Studying Gene Expression Patterns Induced by Hepatotoxicants on Primary Cultures of Rat Hepatocytes by de Longueville, Francoise, Atienzar, Franck A., Marcq, Laurence, Dufrane, Simon, Evrard, Stéphanie, Wouters, Lydia, Leroux, Florence, Bertholet, Vincent, Gerin, Brigitte, Whomsley, Rhys, Arnould, Thierry, Remacle, José, Canning, Mickael

“…In the field of gene expression analysis, DNA microarray technology is having a major impact on many different areas including toxicology. For instance, a…”
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Fuzzy-logic based strategy for validation of multiplex methods: example with qualitative GMO assays by Bellocchi, Gianni, Bertholet, Vincent, Hamels, Sandrine, Moens, W., Remacle, José, Van den Eede, Guy

“…This paper illustrates the advantages that a fuzzy-based aggregation method could bring into the validation of a multiplex method for GMO detection (DualChip ®…”
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Molecular characterization of breast cancer cell lines by a low-density microarray by de Longueville, Francoise, Lacroix, Marc, Barbuto, Anna-Maria, Bertholet, Vincent, Gallo, Dominique, Larsimont, Denis, Marcq, Laurence, Zammatteo, Nathalie, Boffe, Sophie, Leclercq, Guy, Remacle, Jose

“…We designed a low-density microarray carrying 132 DNA capture sequences highly specific for genes known to be differentially expressed among breast tumors and…”
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ABCChips as New Diagnostic Tool to Monitoring Multidrug Resistance in Human Tumor Cells to Chemotherapeutics Agents by Expression Profiling of ATP-Binding Cassette Transporter Genes by Gillet, Jean-Pierre, Efferth, Thomas, Steinbach, Damiel, de Longueville, Françoise, Bertholet, Vincent, Remacle, José, Sayer, Herbert G.

“…A major problem in the treatment of tumors represents the development of resistance to chemotherapy. Many mechanisms are responsible for the failure of…”
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Expression Profiling of ABC-Transporters in Childhood AML Reveals ABCA3 as a Potential Cause of Drug Resistance by Steinbach, Daniel, Gillet, Jean-Pierre, Sauerbrey, Axel, Gruhn, Bernd, Dawczynski, Kristin, de Longueville, Francoise, Bertholet, Vincent, Zintl, Felix, Remacle, Jose, Efferth, Thomas

“…A major issue in the treatment of acute myeloid leukemia (AML) is the development of resistance to chemotherapeutic drugs. While more than 80% of children with…”
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Comparative Clinical and Transcriptomal Profiles of Breast Cancer Between French and South Mediterranean Patients Show Minor but Significative Biological Differences by N. CHALABI, D.J. BERNARD-GALLON, Y.-J. BIGNON, THE BREAST MED CONSORTIUM: F. KWIATKOWSKI, M. AGIER, V. VIDAL, V. LAPLACE-CHABAUD, V. SYLVAIN-VIDAL, V. BERTHOLET, F. DE LONGUEVILLE, M. LACROIX, G. LECLERCQ, J. REMACLE, C. SIBILLE, N. ZAMMATEO, N. BEN JAAFAR, A. SEFIANI, K. OULDIM, A. MÉGARBANÃ, N. JALKH, W. MAHFOUDH, W. TROUDI, A. BEN AMMAR-EL GAÏED, L. CHOUCHANE

“…Background: In Western countries, breast cancer incidence and mortality are higher than in Mediterranean countries. These differences have been ascribed to…”
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