Search Results - "BERTELLI, ROBERTA"
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High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation
Published in Frontiers in immunology (30-04-2019)“…Neutrophils migrate to sites of infection where they phagocytose, degranulate, and/or, in the presence of appropriate stimuli, release decondensed chromatin…”
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A Pilot Study of IL2 in Drug-Resistant Idiopathic Nephrotic Syndrome
Published in PloS one (28-09-2015)“…Tregs infusion reverts proteinuria and reduces renal lesions in most animal models of nephrotic syndrome (i.e. Buffalo/Mna, Adriamycin, Promycin, LPS). IL2…”
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3
Molecular and Cellular Mechanisms for Proteinuria in Minimal Change Disease
Published in Frontiers in medicine (11-06-2018)“…Minimal Change Disease (MCD) is a clinical condition characterized by acute nephrotic syndrome, no evident renal lesions at histology and good response to…”
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4
LPS nephropathy in mice is ameliorated by IL-2 independently of regulatory T cells activity
Published in PloS one (24-10-2014)“…Immunosuppressive regulatory T cells (Tregs) have been hypothesized to exert a protective role in animal models of spontaneous (Buffalo/Mna) and/or drug…”
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Neutrophil Extracellular Traps in Systemic Lupus Erythematosus Stimulate IgG2 Production From B Lymphocytes
Published in Frontiers in medicine (12-04-2021)“…Circulating autoantibodies of IgG2 isotype predominate in Systemic Lupus Erythematosus (SLE) and concur to the development of the renal lesions characteristic…”
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Mesenchymal stem cells protective effect in adriamycin model of nephropathy
Published in Cell transplantation (01-10-2008)“…Mesenchymal stem cells (MSCs) may be of value in regeneration of renal tissue after damage; however, lack of biological knowledge and variability of results in…”
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Neutrophil Extracellular Traps Profiles in Patients with Incident Systemic Lupus Erythematosus and Lupus Nephritis
Published in Journal of rheumatology (01-03-2020)“…Neutrophil extracellular traps (NET) expose modified antigens for autoantibodies in vasculitis. Little is known about levels and removal pathways of NET in…”
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Neutrophil Extracellular Traps protein composition is specific for patients with Lupus nephritis and includes methyl-oxidized αenolase (methionine sulfoxide 93)
Published in Scientific reports (28-05-2019)“…NETs constitute a network of DNA and proteins released by neutrophils in response to infectious and immunologic triggers. NET proteins are recognized as…”
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Adverse events linked with the use of chimeric and humanized anti‐CD20 antibodies in children with idiopathic nephrotic syndrome
Published in British journal of clinical pharmacology (01-06-2018)“…Aims Anti‐CD20 antibodies are increasingly being used to treat idiopathic nephrotic syndrome (INS) in children. While they may allow steroid and calcineurin…”
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10
Heterozygous NPHS1 or NPHS2 mutations in responsive nephrotic syndrome and the multifactorial origin of proteinuria
Published in Kidney international (01-10-2004)Get full text
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Post-translational modified proteins are biomarkers of autoimmune-processes: NETosis and the inflammatory–autoimmunity connection
Published in Clinica chimica acta (01-01-2017)“…Basic research is showing new mechanisms involved in early immune responses and Neutrophil Extracellular Trap (NET) formation (or NETosis) is of key importance…”
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Neutrophil Extracellular Traps (NETs) profiles in patients with incident SLE and lupus nephritis
Published in Journal of rheumatology (15-05-2019)Get full text
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13
Broadening the spectrum of diseases related to podocin mutations
Published in Journal of the American Society of Nephrology (01-05-2003)“…A total of 179 children with sporadic nephrotic syndrome were screened for podocin mutations: 120 with steroid resistance, and 59 with steroid…”
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Recurrence of focal segmental glomerulosclerosis after renal transplantation in patients with mutations of podocin
Published in American journal of kidney diseases (01-06-2003)“…Posttransplant recurrence of focal segmental glomerulosclerosis (FSGS) occurs in a relevant proportion of FSGS patients and represents an important clinical…”
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Prevalence, genetics, and clinical features of patients carrying podocin mutations in steroid-resistant nonfamilial focal segmental glomerulosclerosis
Published in Journal of the American Society of Nephrology (01-12-2001)“…Podocin mutations (NPHS2 gene) are responsible for the autosomal recessive form of steroid-resistant nephrotic syndrome. As a result of a screening for these…”
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Podocin mutations in sporadic focal-segmental glomerulosclerosis occurring in adulthood
Published in Kidney international (01-07-2003)Get full text
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17
Serum glomerular permeability activity in patients with podocin mutations (NPHS2) and steroid-resistant nephrotic syndrome
Published in Journal of the American Society of Nephrology (01-07-2002)“…A plasma factor displaying permeability activity in vitro and possibly determining proteinuria has been hypothesized in idiopathic focal segmental…”
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LPS Nephropathy in Mice Is Ameliorated by IL-2 Independently of Regulatory T Cells Activity: e111285
Published in PloS one (01-10-2014)“…Immunosuppressive regulatory T cells (Tregs) have been hypothesized to exert a protective role in animal models of spontaneous (Buffalo/Mna) and/or drug…”
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19
Cyclosporine in patients with steroid-resistant nephrotic syndrome: an open-label, nonrandomized, retrospective study
Published in Clinical therapeutics (01-09-2004)“…Steroid-resistant nephrotic syndrome (SRNS) with focal segmental glomerulosclerosis has emerged as a leading cause of end-stage renal failure (ESRF) in…”
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20
Heterozygous NPHS1 or NPHS2 mutations in responsive nephrotic syndrome and the multifactorial origin of proteinuria
Published in Kidney international (01-10-2004)Get full text
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