Search Results - "BERRINO, Liberato"

Current pharmacological treatments for COVID‐19: What's next? by Scavone, Cristina, Brusco, Simona, Bertini, Michele, Sportiello, Liberata, Rafaniello, Concetta, Zoccoli, Alice, Berrino, Liberato, Racagni, Giorgio, Rossi, Francesco, Capuano, Annalisa

“…Since December 2019 SARS‐Cov‐2 was found responsible for the disease COVID‐19, which has spread worldwide. No specific therapies/vaccines are yet available for…”
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Chemotherapeutic Drugs and Mitochondrial Dysfunction: Focus on Doxorubicin, Trastuzumab, and Sunitinib by Rosano, Giuseppe, Malara, Natalia, Berrino, L., De Angelis, A., Gorini, Stefania, Ferraro, Elisabetta

“…Many cancer therapies produce toxic side effects whose molecular mechanisms await full elucidation. The most feared and studied side effect of chemotherapeutic…”
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Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity by Urbanek, Konrad, Naviglio, Silvio, Rossi, Francesco, Quaini, F., Illiano, Michela, Prezioso, Lucia, Sapio, Luigi, De Angelis, A., Cappetta, Donato, Berrino, L.

“…The production of reactive species is a core of the redox cycling profile of anthracyclines. However, these molecular characteristics can be viewed as a…”
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Amelioration of diastolic dysfunction by dapagliflozin in a non-diabetic model involves coronary endothelium by Cappetta, Donato, De Angelis, Antonella, Ciuffreda, Loreta Pia, Coppini, Raffaele, Cozzolino, Anna, Miccichè, Agostino, Dell'Aversana, Carmela, D’Amario, Domenico, Cianflone, Eleonora, Scavone, Cristina, Santini, Lorenzo, Palandri, Chiara, Naviglio, Silvio, Crea, Filippo, Rota, Marcello, Altucci, Lucia, Rossi, Francesco, Capuano, Annalisa, Urbanek, Konrad, Berrino, Liberato

“…[Display omitted] The results of trials with sodium-glucose cotransporter 2 (SGLT2) inhibitors raised the possibility that this class of drugs provides…”
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SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy by Cappetta, Donato, Esposito, Grazia, Piegari, Elena, Russo, Rosa, Ciuffreda, Loreta Pia, Rivellino, Alessia, Berrino, Liberato, Rossi, Francesco, De Angelis, Antonella, Urbanek, Konrad

“…Abstract Background Doxorubicin (DOXO) is an effective anti-neoplastic drug but its clinical benefits are hampered by cardiotoxicity. Oxidative stress,…”
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FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development by Chioccarelli, Teresa, Falco, Geppino, Cappetta, Donato, De Angelis, Antonella, Roberto, Luca, Addeo, Martina, Ragusa, Marco, Barbagallo, Davide, Berrino, Liberato, Purrello, Michele, Ambrosino, Concetta, Cobellis, Gilda, Pierantoni, Riccardo, Chianese, Rosanna, Manfrevola, Francesco

“…Circular RNA (circRNA) biogenesis requires a backsplicing reaction, promoted by inverted repeats in cis -flanking sequences and trans factors, such as…”
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Cardioprotective effects of miR-34a silencing in a rat model of doxorubicin toxicity by Piegari, Elena, Cozzolino, Anna, Ciuffreda, Loreta Pia, Cappetta, Donato, De Angelis, Antonella, Urbanek, Konrad, Rossi, Francesco, Berrino, Liberato

“…Cardiotoxicity remains a serious problem in anthracycline-treated oncologic patients. Therapeutic modulation of microRNA expression is emerging as a…”
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Chronic exposure to low dose of bisphenol A impacts on the first round of spermatogenesis via SIRT1 modulation by Chianese, Rosanna, Viggiano, Andrea, Urbanek, Konrad, Cappetta, Donato, Troisi, Jacopo, Scafuro, Marika, Guida, Maurizio, Esposito, Grazia, Ciuffreda, Loreta Pia, Rossi, Francesco, Berrino, Liberato, Fasano, Silvia, Pierantoni, Riccardo, De Angelis, Antonella, Meccariello, Rosaria

“…Spermatogenesis depends on endocrine, autocrine and paracrine communications along the hypothalamus-pituitary-gonad axis. Bisphenol A (BPA), an estrogen-mimic…”
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Angiotensin II and angiotensin 1–7: which is their role in atrial fibrillation? by Mascolo, Annamaria, Urbanek, Konrad, De Angelis, Antonella, Sessa, Maurizio, Scavone, Cristina, Berrino, Liberato, Rosano, Giuseppe Massimo Claudio, Capuano, Annalisa, Rossi, Francesco

“…Atrial fibrillation (AF) is a significant cause of morbidity and mortality as well as a public health burden considering the high costs of AF-related…”
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Neuron-specific enolase serum levels in COVID-19 are related to the severity of lung injury by Cione, Erika, Siniscalchi, Antonio, Gangemi, Pietro, Cosco, Lucio, Colosimo, Manuela, Longhini, Federico, Luciani, Filippo, De Sarro, Giovambattista, Berrino, Liberato, D'Agostino, Bruno, Gallelli, Luca

“…The multifunctional role of neuron-specific enolase (NSE) in lung diseases is well established. As the lungs are greatly affected in COVID-19, we evaluated…”
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Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function by DE ANGELIS, Antonella, PIEGARI, Elena, URBANEK, Konrad, KAJSTURA, Jan, LERI, Annarosa, ROSSI, Francesco, ANVERSA, Piero, CAPPETTA, Donato, MARINO, Laura, FILIPPELLI, Amelia, BERRINO, Liberato, FERREIRA-MARTINS, Joao, HANQIAO ZHENG, HOSODA, Toru, ROTA, Marcello

“…Anthracyclines are the most effective drugs available in the treatment of neoplastic diseases; however, they have profound consequences on the structure and…”
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Quinolones-Induced Musculoskeletal, Neurological, and Psychiatric ADRs: A Pharmacovigilance Study Based on Data From the Italian Spontaneous Reporting System by Scavone, Cristina, Mascolo, Annamaria, Ruggiero, Rosanna, Sportiello, Liberata, Rafaniello, Concetta, Berrino, Liberato, Capuano, Annalisa

“…The use of quinolones has been associated with the development of serious and persistent adverse drug reaction (ADR) mainly affecting muscles, joints and the…”
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Statins Stimulate New Myocyte Formation After Myocardial Infarction by Activating Growth and Differentiation of the Endogenous Cardiac Stem Cells by Cianflone, Eleonora, Cappetta, Donato, Mancuso, Teresa, Sabatino, Jolanda, Marino, Fabiola, Scalise, Mariangela, Albanese, Michele, Salatino, Alessandro, Parrotta, Elvira Immacolata, Cuda, Giovanni, De Angelis, Antonella, Berrino, Liberato, Rossi, Francesco, Nadal-Ginard, Bernardo, Torella, Daniele, Urbanek, Konrad

“…The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) exert pleiotropic effects on cardiac cell biology which are not yet fully…”
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The New Paradigms in Clinical Research: From Early Access Programs to the Novel Therapeutic Approaches for Unmet Medical Needs by Scavone, Cristina, di Mauro, Gabriella, Mascolo, Annamaria, Berrino, Liberato, Rossi, Francesco, Capuano, Annalisa

“…Despite several innovative medicines gaining worldwide approval in recent years, there are still therapeutic areas for which unsatisfied therapeutic needs…”
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The Role of Renin-Angiotensin-Aldosterone System in the Heart and Lung: Focus on COVID-19 by Mascolo, Annamaria, Scavone, Cristina, Rafaniello, Concetta, De Angelis, Antonella, Urbanek, Konrad, di Mauro, Gabriella, Cappetta, Donato, Berrino, Liberato, Rossi, Francesco, Capuano, Annalisa

“…The renin-angiotensin-aldosterone system (RAAS) firstly considered as a cardiovascular circulating hormonal system, it is now accepted as a local tissue system…”
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ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis by Infante, Teresa, Franzese, Monica, Ruocco, Antonio, Schiano, Concetta, Affinito, Ornella, Pane, Katia, Memoli, Domenico, Rizzo, Francesca, Weisz, Alessandro, Bontempo, Paola, Grimaldi, Vincenzo, Berrino, Liberato, Soricelli, Andrea, Mauro, Ciro, Napoli, Claudio

“…Acute coronary syndrome (ACS) is the most severe clinical manifestation of coronary heart disease. We performed an epigenome-wide analysis of circulating CD4 +…”
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The Reporting Frequency of Ketoacidosis Events with Dapagliflozin from the European Spontaneous Reporting System: The DAPA-KETO Study by di Mauro, Gabriella, Mascolo, Annamaria, Gaio, Mario, Rafaniello, Concetta, De Angelis, Antonella, Berrino, Liberato, Paolisso, Giuseppe, Rossi, Francesco, Capuano, Annalisa

“…Dapagliflozin was associated with an increased risk of diabetic ketoacidosis that has led to the European withdrawal of the authorization for the type 1…”
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Renin-Angiotensin System and Coronavirus Disease 2019: A Narrative Review by Mascolo, Annamaria, Scavone, Cristina, Rafaniello, Concetta, Ferrajolo, Carmen, Racagni, Giorgio, Berrino, Liberato, Paolisso, Giuseppe, Rossi, Francesco, Capuano, Annalisa

“…Although clinical manifestations of the 2019 novel coronavirus disease pandemic (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2…”
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Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors, anti-diabetic drugs in heart failure and cognitive impairment: potential mechanisms of the protective effects by Riemma, Maria Antonietta, Mele, Elena, Donniacuo, Maria, Telesca, Marialucia, Bellocchio, Gabriella, Castaldo, Giuseppe, Rossi, Francesco, De Angelis, Antonella, Cappetta, Donato, Urbanek, Konrad, Berrino, Liberato

“…Heart failure and cognitive impairment emerge as public health problems that need to be addressed due to the aging global population. The conditions that often…”
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Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions by Conte, Elena, Mantuano, Paola, Boccanegra, Brigida, Imbrici, Paola, Dinoi, Giorgia, Lenti, Roberta, Cappellari, Ornella, Cappetta, Donato, De Angelis, Antonella, Berrino, Liberato, Gordish-Dressman, Heather, Bianchini, Gianluca, Aramini, Andrea, Allegretti, Marcello, Liantonio, Antonella, De Luca, Annamaria

“…During aging, sarcopenia and decline in physiological processes lead to partial loss of muscle strength, atrophy, and increased fatigability. Muscle changes…”
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