Search Results - "BERNSTEIN, Charles N"

The Brain-Gut Axis and Stress in Inflammatory Bowel Disease by Bernstein, Charles N.

“…The brain-gut axis serves as a circuit that incorporates the human experience, the state of mind, the gut microbiome, and the immune response that ultimately…”
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Brain-Gut Interactions in Inflammatory Bowel Disease by Bonaz, Bruno L, Bernstein, Charles N

“…Psycho-neuro-endocrine-immune modulation through the brain-gut axis likely has a key role in the pathogenesis of inflammatory bowel disease (IBD). The…”
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The Gut Microbiota in Immune-Mediated Inflammatory Diseases by Forbes, Jessica D, Van Domselaar, Gary, Bernstein, Charles N

“…The collection of microbes and their genes that exist within and on the human body, collectively known as the microbiome has emerged as a principal factor in…”
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The Epidemiology of Colectomy in Ulcerative Colitis: Results From a Population-Based Cohort by TARGOWNIK, Laura E, SINGH, Harminder, NUGENT, Zoann, BERNSTEIN, Charles N

“…Previous studies have reported colectomy rates of over 50% in ulcerative colitis (UC), although changes in management may have influenced the rates of…”
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Association between the use of antibiotics in the first year of life and pediatric inflammatory bowel disease by Shaw, Souradet Y, Blanchard, James F, Bernstein, Charles N

“…The development of commensal flora in infants has been shown to be sensitive to antibiotic use. Altered intestinal flora is thought to contribute to the…”
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Persistently High Rate of Venous Thromboembolic Disease in Inflammatory Bowel Disease: A Population-Based Study by Bernstein, Charles N., Nugent, Zoann, Singh, Harminder

“…Venous thromboembolism (VTE) is known to be increased in inflammatory bowel disease (IBD). We aimed to determine whether rates of VTE in IBD have reduced over…”
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AGA Clinical Practice Update on Management of Inflammatory Bowel Disease in Elderly Patients: Expert Review by Ananthakrishnan, Ashwin N., Nguyen, Geoffrey C., Bernstein, Charles N.

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Past and Future Burden of Inflammatory Bowel Diseases Based on Modeling of Population-Based Data by Coward, Stephanie, Clement, Fiona, Benchimol, Eric I., Bernstein, Charles N., Avina-Zubieta, J. Antonio, Bitton, Alain, Carroll, Mathew W., Hazlewood, Glen, Jacobson, Kevan, Jelinski, Susan, Deardon, Rob, Jones, Jennifer L., Kuenzig, M. Ellen, Leddin, Desmond, McBrien, Kerry A., Murthy, Sanjay K., Nguyen, Geoffrey C., Otley, Anthony R., Panaccione, Remo, Rezaie, Ali, Rosenfeld, Greg, Peña-Sánchez, Juan Nicolás, Singh, Harminder, Targownik, Laura E., Kaplan, Gilaad G.

“…Inflammatory bowel diseases (IBDs) exist worldwide, with high prevalence in North America. IBD is complex and costly, and its increasing prevalence places a…”
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Social Determinants of Outcomes in Inflammatory Bowel Disease by Bernstein, Charles N., Walld, Randy, Marrie, Ruth Ann

“…In a population-based inflammatory bowel disease (IBD) cohort, we aimed to determine whether having lower socioeconomic status (LSS) impacted on outcomes. We…”
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Depression and anxiety in inflammatory bowel disease: A review of comorbidity and management by Graff, Lesley A., Walker, John R., Bernstein, Charles N.

“…While there has been a great deal of speculation over the years on the importance of emotional factors in inflammatory bowel disease (IBD), it is only in the…”
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A comparative study of the gut microbiota in immune-mediated inflammatory diseases-does a common dysbiosis exist? by Forbes, Jessica D, Chen, Chih-Yu, Knox, Natalie C, Marrie, Ruth-Ann, El-Gabalawy, Hani, de Kievit, Teresa, Alfa, Michelle, Bernstein, Charles N, Van Domselaar, Gary

“…Immune-mediated inflammatory disease (IMID) represents a substantial health concern. It is widely recognized that IMID patients are at a higher risk for…”
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Infectious and malignant complications of TNF inhibitor therapy in IBD by Targownik, Laura E, Bernstein, Charles N

“…Tumor necrosis factor (TNF) inhibitors are being increasingly utilized in the management of inflammatory bowel disease (IBD). Although the benefits associated…”
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Geographical variability and environmental risk factors in inflammatory bowel disease by Ng, Siew C, Bernstein, Charles N, Vatn, Morten H, Lakatos, Peter Laszlo, Loftus, Jr, Edward V, Tysk, Curt, O'Morain, Colm, Moum, Bjorn, Colombel, Jean-Frédéric

“…The changing epidemiology of inflammatory bowel disease (IBD) across time and geography suggests that environmental factors play a major role in modifying…”
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Rate and Predictors of Early Missed Colorectal Cancers After Colonoscopy in Manitoba: A Population-Based Study by Singh, Harminder, Nugent, Zoann, Demers, Alain A, Bernstein, Charles N

“…Many of the colorectal cancers (CRCs) diagnosed within 3 years after a colonoscopy are likely because of lesions missed on the initial colonoscopy. In this…”
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Higher Incidence of Clostridium difficile Infection Among Individuals With Inflammatory Bowel Disease by Singh, Harminder, MD MPH, Nugent, Zoann, PhD, Yu, B Nancy, PhD, Lix, Lisa M., PhD, Targownik, Laura E., MD, MSHS, Bernstein, Charles N., MD

“…Abstract Background & Aims Studies of Clostridium difficile infections (CDIs) among individuals with inflammatory bowel disease (IBD) have used data from…”
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Increased Burden of Psychiatric Disorders in Inflammatory Bowel Disease by Bernstein, Charles N, Hitchon, Carol A, Walld, Randy, Bolton, James M, Sareen, Jitender, Walker, John R, Graff, Lesley A, Patten, Scott B, Singer, Alexander, Lix, Lisa M, El-Gabalawy, Renée, Katz, Alan, Fisk, John D, Marrie, Ruth Ann

“…Abstract Background Psychiatric comorbidity in inflammatory bowel disease (IBD) is well known; however, data from a truly representative sample are sparse. We…”
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Association Between the Use of Antibiotics and New Diagnoses of Crohn's Disease and Ulcerative Colitis by SHAW, Souradet Y, BLANCHARD, James F, BERNSTEIN, Charles N

“…The objective of this study was to determine if the use of antibiotics 2-5 years before diagnosis was associated with the development of inflammatory bowel…”
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Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population-Based Provincial Health Administrative Databases by Benchimol, Eric I, Bernstein, Charles N, Bitton, Alain, Carroll, Matthew W, Singh, Harminder, Otley, Anthony R, Vutcovici, Maria, El-Matary, Wael, Nguyen, Geoffrey C, Griffiths, Anne M, Mack, David R, Jacobson, Kevan, Mojaverian, Nassim, Tanyingoh, Divine, Cui, Yunsong, Nugent, Zoann J, Coulombe, Janie, Targownik, Laura E, Jones, Jennifer L, Leddin, Desmond, Murthy, Sanjay K, Kaplan, Gilaad G

“…The incidence of pediatric-onset inflammatory bowel disease (IBD) is increasing worldwide. We used population-based health administrative data to determine…”
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Microbiome Survey of the Inflamed and Noninflamed Gut at Different Compartments Within the Gastrointestinal Tract of Inflammatory Bowel Disease Patients by Forbes, Jessica D, Van Domselaar, Gary, Bernstein, Charles N

“…We aimed to contrast the mucosal microbiota in Crohn's disease (CD) and ulcerative colitis (UC). We assessed the concept of localized dysbiosis by comparing…”
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Clinical Practice Guidelines for the Medical Management of Nonhospitalized Ulcerative Colitis: The Toronto Consensus by Bressler, Brian, Marshall, John K, Bernstein, Charles N, Bitton, Alain, Jones, Jennifer, Leontiadis, Grigorios I, Panaccione, Remo, Steinhart, A. Hillary, Tse, Francis, Feagan, Brian

“…Background & Aims The medical management of ulcerative colitis (UC) has improved through the development of new therapies and novel approaches that optimize…”
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