Search Results - "BERNIER, S. G"

An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis by Lazarus, D. D., Doyle, E. G., Bernier, S. G., Rogers, A. B., Labenski, M. T., Wakefield, J. D., Karp, R. M., Clark, E. J., Lorusso, J., Hoyt, J. G., Thompson, C. D., Hannig, G., Westlin, W. F.

“… Objective: To elucidate the role of methionine aminopeptidase type-2 (MetAP-2) in the clinical pathology of rheumatoid arthritis, arthritis was induced in…”
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Prostanoid receptors: ontogeny and implications in vascular physiology by Wright, D H, Abran, D, Bhattacharya, M, Hou, X, Bernier, S G, Bouayad, A, Fouron, J C, Vazquez-Tello, A, Beauchamp, M H, Clyman, R I, Peri, K, Varma, D R, Chemtob, S

“…Prostanoids exert significant effects on circulatory beds. They play a role in the response of the vasculature to adjustments in perfusion pressure and oxygen…”
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Bradykinin-regulated Interactions of the Mitogen-activated Protein Kinase Pathway with the Endothelial Nitric-oxide Synthase by Bernier, Sylvie G., Haldar, Saptarsi, Michel, Thomas

“…Activation of the bradykinin B2 receptor in endothelial cells initiates a complex array of cellular responses mediated by diverse signaling pathways, including…”
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A specific binding site recognizing a fragment of angiotensin II in bovine adrenal cortex membranes by Bernier, S G, Fournier, A, Guillemette, G

“…We have characterized a specific binding site for angiotensin IV in bovine adrenal cortex membranes. Pseudo-equilibrium studies at 37 degrees C for 2 h have…”
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Modulation of Pro-inflammatory Gene Expression by Nuclear Lysophosphatidic Acid Receptor Type-1 by Gobeil, Fernand, Bernier, Sylvie G., Vazquez-Tello, Alejandro, Brault, Sonia, Beauchamp, Martin H., Quiniou, Christiane, Marrache, Anne Marilise, Checchin, Daniella, Sennlaub, Florian, Hou, Xin, Nader, Mony, Bkaily, Ghassan, Ribeiro-da-Silva, Alfredo, Goetzl, Edward J., Chemtob, Sylvain

“…Lysophosphatidic acid (LPA) is a bioactive molecule involved in inflammation, immunity, wound healing, and neoplasia. Its pleiotropic actions arise presumably…”
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Characterization of a binding site for angiotensin IV on bovine aortic endothelial cells by Bernier, Sylvie G., Servant, Guy, Boudreau, Manon, Fournier, Alain, Guillemette, Gaétan

“…We have characterized a specific binding site for angiotensin IV on bovine aortic endothelial cell membranes. Pseudo-equilibrium studies at 37°C for 2 h have…”
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Proinflammatory Gene Induction by Platelet-Activating Factor Mediated Via Its Cognate Nuclear Receptor by Marrache, A. Marilise, Gobeil, Fernand, Jr, Bernier, Sylvie G, Stankova, Jana, Rola-Pleszczynski, Marek, Choufani, Sanaa, Bkaily, Ghassan, Bourdeau, Annie, Sirois, Martin G, Vazquez-Tello, Alejandro, Fan, Li, Joyal, Jean-Sebastien, Filep, Janos G, Varma, Daya R, Ribeiro-da-Silva, Alfredo, Chemtob, Sylvain

“…It has been postulated that intracellular binding sites for platelet-activating factor (PAF) contribute to proinflammatory responses to PAF. Isolated nuclei…”
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Characterization of AT4 Receptor from Bovine Aortic Endothelium with Photosensitive Analogues of Angiotensin IV by Bernier, Sylvie G, Bellemare, Julie M. L, Escher, Emanuel, Guillemette, Gaétan

“…Newly developed photosensitive analogues of AngIV were used to characterize the AT4 receptor of bovine aortic endothelial cells. The photoactivatable AngIV…”
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Permeability of endothelial monolayers to albumin is increased by bradykinin and inhibited by prostaglandins by Farmer, P J, Bernier, S G, Lepage, A, Guillemette, G, Regoli, D, Sirois, P

“…Using monolayers of bovine aortic endothelial cells (BAEC) in modified Boyden chambers, we examined the role of prostaglandins (PGs) in the bradykinin…”
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N- and C-terminal structure-activity study of angiotensin II on the angiotensin AT2 receptor by BOULEY, R, PERODIN, J, PLANTE, H, RIHAKOVA, L, BERNIER, S. G, MALETINSKA, L, GUILLEMETTE, G, ESCHER, E

“…The predominant angiotensin II receptor expressed in the human myometrium is the angiotensin AT2 receptor. This preparation was used for a structure-activity…”
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Monitoring of phospholipase A2 activation in cultured cells using tritiated arachidonic acid by Briand, S I, Bernier, S G, Guillemette, G

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Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells by Igarashi, J, Bernier, S G, Michel, T

“…Sphingosine 1-phosphate (S1P) is a platelet-derived sphingolipid that elicits numerous biological responses in endothelial cells mediated by a family of G…”
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Desensitization of AT1 Receptor-Mediated Cellular Responses Requires Long Term Receptor Down-Regulation in Bovine Adrenal Glomerulosa Cells by Richard, Darren E., Laporte, Stéphane A., Bernier, Sylvie G., Leduc, Richard, Guillemette, Gaétan

“…Abstract Angiotensin II (Ang II) regulates aldosterone production in bovine adrenal glomerulosa cells by interacting with the AT1 receptor. This receptor is…”
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Study on the functionality and molecular properties of the AT4 receptor by Briand, S. I., Bellemare, J. M. L., Bernier, S. G., Guillemette, G.

“…Whereas the role of angiotensin II (Ang II) has been clarified in numerous tissues and cell types, the physiological relevance of its C-terminal (3-8)…”
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Adenosine induces cyclic-AMP formation and inhibits endothelin-1 production/secretion in guinea-pig tracheal epithelial cells through A(2B) adenosine receptors by Pelletier, S, Dubé, J, Villeneuve, A, Gobeil, Jr, F, Bernier, S G, Battistini, B, Guillemette, G, Sirois, P

“…1. The adenosine receptor subtype mediating adenosine 3' : 5'-cyclic monophosphate (cyclic AMP) formation and the effect of its activation on endothelin-1…”
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Methionine aminopeptidases type I and type II are essential to control cell proliferation by Bernier, Sylvie G., Taghizadeh, Nazbeh, Thompson, Charles D., Westlin, William F., Hannig, Gerhard

“…The dependence of cell growth on methionine aminopeptidase (MetAP) function in bacteria and yeast is firmly established. Here we report experimental evidence…”
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A Methionine Aminopeptidase-2 Inhibitor, PPI-2458, for the Treatment of Rheumatoid Arthritis by Bernier, Sylvie G., Lazarus, Douglas D., Clark, Edward, Doyle, Beth, Labenski, Matthew T., Thompson, Charles D., Westlin, William F., Hannig, Gerhard, Erikson, R. L.

“…The hallmark of rheumatoid arthritis (RA) is the progressive destruction of articular joints, characterized by invasive synovial hyperplasia and pathological…”
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Regulation of eNOS Expression in Brain Endothelial Cells by Perinuclear EP3 Receptors by Gobeil, Fernand, Dumont, Isabelle, Marrache, Anne Marilise, Vazquez-Tello, Alejandro, Bernier, Sylvie G, Abran, Daniel, Hou, Xin, Beauchamp, Martin H, Quiniou, Christiane, Bouayad, Asmaa, Choufani, Sanaa, Bhattacharya, Mousumi, Molotchnikoff, Stephane, Ribeiro-da-Silva, Alfredo, Varma, Daya R, Bkaily, Ghassan, Chemtob, Sylvain

“…We reported upregulation of endothelial nitric oxide synthase (eNOS) by PGE2 in tissues and presence of perinuclear PGE2 receptors (EP). We presently studied…”
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Calcium-calmodulin plays a major role in bradykinin-induced arachidonic acid release by bovine aortic endothelial cells by Briand, Sandie I., Bernier, Sylvie G., Guillemette, Gaétan

“…We provided evidence that calcium‐calmodulin plays a major role in bradykinin‐induced arachidonic acid release by bovine aortic endothelial cells. In cells…”
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2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite by Hou, X, Roberts, 2nd, L J, Taber, D F, Morrow, J D, Kanai, K, Gobeil, Jr, F, Beauchamp, M H, Bernier, S G, Lepage, G, Varma, D R, Chemtob, S

“…15-F(2t)-isoprostane (15-F(2t)-IsoP), also termed 8-isoprostaglandin F(2alpha), is one of a series of prostanoids formed by free radical-mediated peroxidation…”
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