Search Results - "BERNHARDT, Starr X"

Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate by HAMBLETT, Kevin J, SENTER, Peter D, MEYER, Damon L, FRANCISCO, Joseph A, CHACE, Dana F, SUN, Michael M. C, LENOX, Joel, CERVENY, Charles G, KISSLER, Kim M, BERNHARDT, Starr X, KOPCHA, Anastasia K, ZABINSKI, Roger F

“…Purpose: An antibody-drug conjugate consisting of monomethyl auristatin E (MMAE) conjugated to the anti-CD30 monoclonal antibody (mAb) cAC10, with eight drug…”
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Development and Properties of β-Glucuronide Linkers for Monoclonal Antibody−Drug Conjugates by Jeffrey, Scott C, Andreyka, Jamie B, Bernhardt, Starr X, Kissler, Kim M, Kline, Toni, Lenox, Joel S, Moser, Ruth F, Nguyen, Minh T, Okeley, Nicole M, Stone, Ivan J, Zhang, Xinqun, Senter, Peter D

“…A β-glucuronide-based linker for attaching cytotoxic agents to monoclonal antibodies (mAbs) was designed and evaluated. We employed the cytotoxic auristatin…”
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