Search Results - "BERNHARDT, Gunter"

Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis by Avouac, Jérôme, Elhai, Muriel, Tomcik, Michal, Ruiz, Barbara, Friese, Manuel, Piedavent, Melanie, Colonna, Marco, Bernhardt, Gunter, Kahan, André, Chiocchia, Gilles, Distler, Jörg H W, Allanore, Yannick

“…To investigate the contribution of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of dermal fibrosis on gene inactivation and…”
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Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination by Barros-Martins, Joana, Hammerschmidt, Swantje I., Cossmann, Anne, Odak, Ivan, Stankov, Metodi V., Morillas Ramos, Gema, Dopfer-Jablonka, Alexandra, Heidemann, Annika, Ritter, Christiane, Friedrichsen, Michaela, Schultze-Florey, Christian, Ravens, Inga, Willenzon, Stefanie, Bubke, Anja, Ristenpart, Jasmin, Janssen, Anika, Ssebyatika, George, Bernhardt, Günter, Münch, Jan, Hoffmann, Markus, Pöhlmann, Stefan, Krey, Thomas, Bošnjak, Berislav, Förster, Reinhold, Behrens, Georg M. N.

“…Currently approved viral vector-based and mRNA-based vaccine approaches against coronavirus disease 2019 (COVID-19) consider only homologous prime-boost…”
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Coming of Age: CD96 Emerges as Modulator of Immune Responses by Georgiev, Hristo, Ravens, Inga, Papadogianni, Georgia, Bernhardt, Günter

“…CD96 represents a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD96 is expressed mainly by cells of hematopoietic origin, in…”
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TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy by Yamada, Toshiki, Tatematsu, Megumi, Takasuga, Shunsuke, Fuchimukai, Akane, Yamagata, Kenki, Seki, Shinsuke, Kuba, Keiji, Yoshida, Hideyuki, Taniuchi, Ichiro, Bernhardt, Günter, Shibuya, Kazuko, Shibuya, Akira, Yamada, Takechiyo, Ebihara, Takashi

“…While group-2 innate lymphoid cells (ILC2s) are highly proliferative in allergic inflammation, the removal of overactivated ILC2s in allergic diseases has not…”
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puzzle of intestinal lamina propria dendritic cells and macrophages by Pabst, Oliver, Bernhardt, Günter

“…A specialized network of immune cells is positioned directly in the mucosa of the intestinal tract. In this Viewpoint, we discuss the nature and function of DC…”
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Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets by Georgiev, Hristo, Ravens, Inga, Benarafa, Charaf, Förster, Reinhold, Bernhardt, Günter

“…Invariant natural killer T (iNKT) cells comprise a subpopulation of innate lymphocytes developing in thymus. A new model proposes subdividing murine iNKT cells…”
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Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells by Worbs, Tim, Bode, Ulrike, Yan, Sheng, Hoffmann, Matthias W, Hintzen, Gabriele, Bernhardt, Günter, Förster, Reinhold, Pabst, Oliver

“…Oral tolerance induction is a key feature of intestinal immunity, generating systemic nonresponsiveness to ingested antigens. In this study, we report that…”
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Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods by Bošnjak, Berislav, Stein, Saskia Catherina, Willenzon, Stefanie, Cordes, Anne Katrin, Puppe, Wolfram, Bernhardt, Günter, Ravens, Inga, Ritter, Christiane, Schultze-Florey, Christian R., Gödecke, Nina, Martens, Jörg, Kleine-Weber, Hannah, Hoffmann, Markus, Cossmann, Anne, Yilmaz, Mustafa, Pink, Isabelle, Hoeper, Marius M., Behrens, Georg M. N., Pöhlmann, Stefan, Blasczyk, Rainer, Schulz, Thomas F., Förster, Reinhold

“…Neutralizing antibodies targeting the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) block severe acute respiratory syndrome coronavirus 2…”
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Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination by Hammerschmidt, Swantje I., Thurm, Christoph, Bošnjak, Berislav, Bernhardt, Günter, Reinhold, Annegret, Willenzon, Stefanie, Ritter, Christiane, Reinhold, Dirk, Schraven, Burkhart, Förster, Reinhold

“…Sera of vaccines were assessed by surrogate virus neutralization tests for their capacity to neutralize the SARS‐CoV‐2 Delta variant. Homologous prime‐boost…”
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CD155/CD226‐interaction impacts on the generation of innate CD8+ thymocytes by regulating iNKT‐cell differentiation by Georgiev, Hristo, Ravens, Inga, Shibuya, Akira, Förster, Reinhold, Bernhardt, Günter

“…The cell surface receptor CD155 influences a variety of immune processes by binding to its ligands CD226, CD96, or TIGIT. Here, we report that the interaction…”
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Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy by Blake, Stephen J, Stannard, Kimberley, Liu, Jing, Allen, Stacey, Yong, Michelle C R, Mittal, Deepak, Aguilera, Amelia Roman, Miles, John J, Lutzky, Viviana P, de Andrade, Lucas Ferrari, Martinet, Ludovic, Colonna, Marco, Takeda, Kazuyoshi, Kühnel, Florian, Gurlevik, Engin, Bernhardt, Günter, Teng, Michele W L, Smyth, Mark J

“…CD96 has recently been shown as a negative regulator of mouse natural killer (NK)-cell activity, with Cd96(-/-)mice displaying hyperresponsive NK cells upon…”
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Healthy-like CD4 + Regulatory and CD4 + Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion by Schneider, Jessica, Kuhlmann, Leonie, Xiao, Yankai, Raha, Solaiman, Bernhardt, Günter, Stadler, Michael, Thol, Felicitas, Heuser, Michael, Eder, Matthias, Ganser, Arnold, Ravens, Sarina, Förster, Reinhold, Prinz, Immo, Koenecke, Christian, Schultze-Florey, Christian R

“…Donor lymphocyte infusion (DLI) can (re-)induce durable remission in relapsing patients after allogeneic hematopoietic stem-cell transplantation (alloHSCT)…”
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TACTILE becomes tangible: CD96 discloses its inhibitory peculiarities: the receptor CD96 inhibits cytokine production by natural killer cells in mice and antagonizes activation mediated by the receptor CD226 by Bernhardt, Gunter

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Sphingosine-1-Phosphate Mediates Migration of Mature Dendritic Cells by Czeloth, Niklas, Bernhardt, Gunter, Hofmann, Fred, Genth, Harald, Forster, Reinhold

“…Sphingosine-1-phosphate (S1P) represents a potent modulator of diverse cellular activities, including lymphocyte trafficking and maintenance of lymphocyte…”
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Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination by Hammerschmidt, Swantje I., Bosnjak, Berislav, Bernhardt, Günter, Friedrichsen, Michaela, Ravens, Inga, Dopfer-Jablonka, Alexandra, Hoffmann, Markus, Pöhlmann, Stefan, Behrens, Georg M. N., Förster, Reinhold

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Development and functional specialization of CD103⁺ dendritic cells by del Rio, Maria-Luisa, Bernhardt, Günter, Rodriguez-Barbosa, Jose-Ignacio, Förster, Reinhold

“…CD103 (αE) integrin expression distinguishes a population of dendritic cells (DCs) that can be found in many if not all lymphoid and non-lymphoid organs…”
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BNT162b2-boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19 by Behrens, Georg M. N., Barros-Martins, Joana, Cossmann, Anne, Ramos, Gema Morillas, Stankov, Metodi V., Odak, Ivan, Dopfer-Jablonka, Alexandra, Hetzel, Laura, Köhler, Miriam, Patzer, Gwendolyn, Binz, Christoph, Ritter, Christiane, Friedrichsen, Michaela, Schultze-Florey, Christian, Ravens, Inga, Willenzon, Stefanie, Bubke, Anja, Ristenpart, Jasmin, Janssen, Anika, Ssebyatika, George, Krähling, Verena, Bernhardt, Günter, Hoffmann, Markus, Pöhlmann, Stefan, Krey, Thomas, Bošnjak, Berislav, Hammerschmidt, Swantje I., Förster, Reinhold

“…Heterologous prime/boost vaccination with a vector-based approach (ChAdOx-1nCov-19, ChAd) followed by an mRNA vaccine (e.g. BNT162b2, BNT) has been reported to…”
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Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus by Papadogianni, Georgia, Ravens, Inga, Dittrich-Breiholz, Oliver, Bernhardt, Günter, Georgiev, Hristo

“…Invariant natural killer T (iNKT) cells represent a subclass of T cells possessing a restricted repertoire of T cell receptors enabling them to recognize lipid…”
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Longitudinal Tracking of Immune Responses in COVID-19 Convalescents Reveals Absence of Neutralization Activity Against Omicron and Staggered Impairment to Other SARS-CoV-2 Variants of Concern by Odak, Ivan, Schultze-Florey, Christian R, Hammerschmidt, Swantje I, Ritter, Christiane, Willenzon, Stefanie, Friedrichsen, Michaela, Ravens, Inga, Sikora, Ruth, Bayir, Lâle M, Gutierrez Jauregui, Rodrigo, Bernhardt, Günter, Stankov, Metodi V, Cossmann, Anne, Hansen, Guido, Krey, Thomas, Cornberg, Markus, Koenecke, Christian, Behrens, Georg M N, Bošnjak, Berislav, Förster, Reinhold

“…Evaluating long-term protection against SARS-CoV-2 variants of concern in convalescing individuals is of high clinical relevance. In this prospective study of…”
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Expression of CD226 is associated to but not required for NK cell education by Wagner, Arnika K., Kadri, Nadir, Snäll, Johanna, Brodin, Petter, Gilfillan, Susan, Colonna, Marco, Bernhardt, Günter, Höglund, Petter, Kärre, Klas, Chambers, Benedict J.

“…DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an activating receptor expressed on subsets of natural killer (NK) and T cells, interacts with its…”
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