Search Results - "BERKOWITZ, Dan E"

Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41 by Natarajan, Niranjana, Hori, Daijiro, Flavahan, Sheila, Steppan, Jochen, Flavahan, Nicholas A, Berkowitz, Dan E, Pluznick, Jennifer L

“…Short chain fatty acid (SCFA) metabolites are byproducts of gut microbial metabolism that are known to affect host physiology via host G protein-coupled…”
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Hydrogen Sulfide as Endothelium-Derived Hyperpolarizing Factor Sulfhydrates Potassium Channels by Mustafa, Asif K., Sikka, Gautam, Gazi, Sadia K., Steppan, Jochen, Jung, Sung M., Bhunia, Anil K., Barodka, Viachaslau M., Gazi, Farah K., Barrow, Roxanne K., Wang, Rui, Amzel, L. Mario, Berkowitz, Dan E., Snyder, Solomon H.

“…Nitric oxide, the classic endothelium-derived relaxing factor (EDRF), acts through cyclic GMP and calcium without notably affecting membrane potential. A major…”
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miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling by Hori, Daijiro, Dunkerly-Eyring, Brittany, Nomura, Yohei, Biswas, Debjit, Steppan, Jochen, Henao-Mejia, Jorge, Adachi, Hideo, Santhanam, Lakshmi, Berkowitz, Dan E, Steenbergen, Charles, Flavell, Richard A, Das, Samarjit

“…Endothelial dysfunction and arterial stiffening play major roles in cardiovascular diseases. The critical role for the miR-181 family in vascular inflammation…”
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Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats by Carrillo-Sepulveda, Maria Alicia, Spitler, Kathryn, Pandey, Deepesh, Berkowitz, Dan E., Matsumoto, Takayuki

“…Hyperglycemia-induced reactive oxygen species (ROS) production plays a major role in the pathogenesis of diabetic vascular dysfunction. However, the underlying…”
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Decreased Erythrocyte Deformability After Transfusion and the Effects of Erythrocyte Storage Duration by Frank, Steven M., Abazyan, Bagrat, Ono, Masahiro, Hogue, Charles W., Cohen, David B., Berkowitz, Dan E., Ness, Paul M., Barodka, Viachaslau M.

“…Erythrocyte cell membranes undergo morphologic changes during storage, but it is unclear whether these changes are reversible. We assessed erythrocyte cell…”
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Arginase and vascular aging by Santhanam, Lakshmi, Christianson, David W, Nyhan, Daniel, Berkowitz, Dan E

“…Departments of 1 Anesthesiology and Critical Care Medicine and 2 Biomedical Engineering; and Johns Hopkins University School of Medicine, Baltimore, Maryland;…”
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Olfactory, Taste, and Photo Sensory Receptors in Non-sensory Organs: It Just Makes Sense by Dalesio, Nicholas M, Barreto Ortiz, Sebastian F, Pluznick, Jennifer L, Berkowitz, Dan E

“…Sensory receptors that detect and respond to light, taste, and smell primarily belong to the G-protein-coupled receptor (GPCR) superfamily. In addition to…”
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Melanopsin mediates light-dependent relaxation in blood vessels by Sikka, Gautam, Hussmann, G. Patrick, Pandey, Deepesh, Cao, Suyi, Hori, Daijiro, Park, Jong Taek, Steppan, Jochen, Kim, Jae Hyung, Barodka, Viachaslau, Myers, Allen C., Santhanam, Lakshmi, Nyhan, Daniel, Halushka, Marc K., Koehler, Raymond C., Snyder, Solomon H., Shimoda, Larissa A., Berkowitz, Dan E.

“…Melanopsin (opsin4; Opn4), a non-image-forming opsin, has been linked to a number of behavioral responses to light, including circadian photo-entrainment,…”
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Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin by Bruning, Rebecca S, Santhanam, Lakshmi, Stanhewicz, Anna E, Smith, Caroline J, Berkowitz, Dan E, Kenney, W Larry, Holowatz, Lacy A

“…Local skin heating is used to assess microvascular function in clinical populations because NO is required for full expression of the response; however,…”
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OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling by Ryoo, Sungwoo, Bhunia, Anil, Chang, Fumin, Shoukas, Artin, Berkowitz, Dan E, Romer, Lewis H

“…Abstract Aims Arginase II regulates NOS activity by competing for the substrate l -arginine. Oxidized LDL (OxLDL) is a proatherogenic molecule that activates…”
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Upregulation of Inducible Nitric Oxide Synthase Contributes to Attenuated Cutaneous Vasodilation in Essential Hypertensive Humans by Smith, Caroline J, Santhanam, Lakshmi, Bruning, Rebecca S, Stanhewicz, Anna, Berkowitz, Dan E, Holowatz, Lacy A

“…Essential hypertension is a proinflammatory, proconstrictor disease coinciding with endothelial dysfunction and inward vessel remodeling. Using the skin…”
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Deciphering the Role of microRNAs in Large-Artery Stiffness Associated With Aging: Focus on miR-181b by Baraban, Jay M, Tuday, Eric, Berkowitz, Dan E, Das, Sam

“…Large artery stiffness (LAS) is a major, independent risk factor underlying cardiovascular disease that increases with aging. The emergence of microRNA…”
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Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats by Kim, Jae Hyung, Bugaj, Lukasz J, Oh, Young Jun, Bivalacqua, Trinity J, Ryoo, Sungwoo, Soucy, Kevin G, Santhanam, Lakshmi, Webb, Alanah, Camara, Andre, Sikka, Gautam, Nyhan, Daniel, Shoukas, Artin A, Ilies, Monica, Christianson, David W, Champion, Hunter C, Berkowitz, Dan E

“…Department of 1 Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland; ; Department of 2 Biomedical Engineering,…”
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Vascular Stiffness and Increased Pulse Pressure in the Aging Cardiovascular System by Nyhan, Daniel, Berkowitz, Dan E., Barodka, Viachaslau, Steppan, Jochen

“…Aging leads to a multitude of changes in the cardiovascular system, including systolic hypertension, increased central vascular stiffness, and increased pulse…”
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Difference between ejection times measured at two different peripheral locations as a novel marker of vascular stiffness by Obata, Yurie, Ruzankin, Pavel, Berkowitz, Dan E, Steppan, Jochen, Barodka, Viachaslau

“…Pulse wave velocity (PWV) has been recommended as an arterial damage assessment tool and a surrogate of arterial stiffness. However, the current technology…”
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Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice by Jung, Sung Mee, Jandu, Simran, Steppan, Jochen, Belkin, Alexey, An, Steven S, Pak, Alina, Choi, Eric Y, Nyhan, Daniel, Butlin, Mark, Viegas, Kayla, Avolio, Alberto, Berkowitz, Dan E, Santhanam, Lakshmi

“…Nitric oxide (NO) can modulate arterial stiffness by regulating both functional and structural changes in the arterial wall. Tissue transglutaminase (TG2) has…”
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Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress by Bivalacqua, Trinity J, Musicki, Biljana, Hsu, Lewis L, Berkowitz, Dan E, Champion, Hunter C, Burnett, Arthur L

“…Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical…”
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Light-Mediated Inhibition of Colonic Smooth Muscle Constriction and Colonic Motility via Opsin 3 by Dan, William, Park, Ga Hyun, Vemaraju, Shruti, Wu, Amy D, Perez, Kristina, Rao, Meenakshi, Berkowitz, Dan E, Lang, Richard A, Yim, Peter D

“…Opsin photoreceptors outside of the central nervous system have been shown to mediate smooth muscle photorelaxation in several organs. We hypothesized that…”
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Ejection time: influence of hemodynamics and site of measurement in the arterial tree by Obata, Yurie, Mizogami, Maki, Singh, Sarabdeep, Nyhan, Daniel, Berkowitz, Dan E, Steppan, Jochen, Barodka, Viachaslau

“…The left ventricular ejection time is routinely measured from a peripheral arterial waveform. However, the arterial waveform undergoes constant transformation…”
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Editorial: Regulation of Vascular Function by Circulating Blood by Rifkind, Joseph M, Berkowitz, Dan E, Mohanty, Joy G

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