Search Results - "BERKING, Carola"

Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion by Simon, David, Tascilar, Koray, Krönke, Gerhard, Kleyer, Arnd, Zaiss, Mario M., Heppt, Franz, Meder, Christine, Atreya, Raja, Klenske, Entcho, Dietrich, Peter, Abdullah, Abdullah, Kliem, Thorsten, Corte, Giulia, Morf, Harriet, Leppkes, Moritz, Kremer, Andreas E., Ramming, Andreas, Pachowsky, Milena, Schuch, Florian, Ronneberger, Monika, Kleinert, Stefan, Maier, Clara, Hueber, Axel J., Manger, Karin, Manger, Bernhard, Berking, Carola, Tenbusch, Matthias, Überla, Klaus, Sticherling, Michael, Neurath, Markus F., Schett, Georg

“…Immune-mediated inflammatory diseases (IMIDs) of the joints, gut and skin are treated with inhibitors of inflammatory cytokines. These cytokines are involved…”
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Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial by Leiter, Ulrike, Dr, Stadler, Rudolf, MD, Mauch, Cornelia, Prof, Hohenberger, Werner, Prof, Brockmeyer, Norbert, Prof, Berking, Carola, Prof, Sunderkötter, Cord, Prof, Kaatz, Martin, MD, Schulte, Klaus-Werner, MD, Lehmann, Percy, MD, Vogt, Thomas, Prof, Ulrich, Jens, MD, Herbst, Rudolf, MD, Gehring, Wolfgang, MD, Simon, Jan-Christoph, Prof, Keim, Ulrike, PhD, Martus, Peter, Prof, Garbe, Claus, Prof

“…Summary Background Complete lymph node dissection is recommended in patients with positive sentinel lymph node biopsy results. To date, the effect of complete…”
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Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task by Brinker, Titus J., Hekler, Achim, Enk, Alexander H., Klode, Joachim, Hauschild, Axel, Berking, Carola, Schilling, Bastian, Haferkamp, Sebastian, Schadendorf, Dirk, Holland-Letz, Tim, von Kalle, Christof, Sirokay, Judith, Albrecht, Magarete, Chorti, Eleftheria, Dith, Anna, Drusio, Christina, Giese, Nina, Griewank, Klaus, Hallasch, Sandra, Hanhart, Zdenka, Herz, Saskia, Hohaus, Katja, Jansen, Philipp, Jockenhöfer, Finja, Kanaki, Theodora, Leonhard, Katja, Matei, Liliana, Olischewski, Alexandra, Placke, Jan-Malte, Raub, Simon, Salva, Katrin, Sody, Elsa, Steingrube, Nadine, Ugurel, Selma, Zaremba, Anne, Gebhardt, Christoffer, Booken, Nina, Buder-Bakhaya, Kristina, Bokor-Billmann, Therezia, Enk, Alexander, Hänßle, Holger, Salzmann, Martin, Schank, Timo, Bohne, Ann-Sophie, Egberts, Friederike, Ewald, Benjamin, Falkvoll, Sandra, Gerdes, Sascha, Harde, Viola, Hauschild, Axel, Jost, Marion, Kosova, Katja, Messinger, Laetitia, Metzner, Malte, Scheller, Natalie, Schwarz, Thomas, Stölzl, Dora, Thielking, Federieke, Tomaschewski, Elena, Wehkamp, Ulrike, Wiedow, Oliver, Bender-Säbelkampf, Sophia, Horbrügger, Marc, Karoglan, Ante, Kraas, Luise, Geraud, Cyrill, Koch, Philipp, Linke, Miriam, Maurier, Nolwenn, Müller, Verena, Thomas, Benjamin, Utikal, Jochen Sven, Alamri, Ali Saeed M., Baczako, Andrea, Berking, Carola, Betke, Matthias, Haas, Carolin, Hartmann, Daniela, Kilian, Katharina, Krammer, Sebastian, Lapczynski, Natalie Lidia, Nasifoglu, Suzan, Ruini, Cristel, Wolff, Hans, Achatz, Birgit, Bergbreiter, Astrid, Drexler, Konstantin, Halupczok, Anna, Hegemann, Marie, Dinauer, Verena, Maagk, Maria, Mickler, Marion, Philipp, Biance, Wittmann, Constanze, Gesierich, Anja, Glutsch, Valerie, Kahlert, Katrin, Kerstan, Andreas, Schilling, Bastian, Schrüfer, Philipp

“…Recent studies have successfully demonstrated the use of deep-learning algorithms for dermatologist-level classification of suspicious lesions by the use of…”
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Superior skin cancer classification by the combination of human and artificial intelligence by Hekler, Achim, Enk, Alexander H., Hauschild, Axel, Weichenthal, Michael, Maron, Roman C., Berking, Carola, Haferkamp, Sebastian, Klode, Joachim, Schadendorf, Dirk, Schilling, Bastian, Holland-Letz, Tim, Izar, Benjamin, von Kalle, Christof, Fröhling, Stefan, Brinker, Titus J., Schmitt, Laurenz, Peitsch, Wiebke K., Hoffmann, Friederike, Becker, Jürgen C., Drusio, Christina, Jansen, Philipp, Klode, Joachim, Lodde, Georg, Sammet, Stefanie, Schadendorf, Dirk, Sondermann, Wiebke, Ugurel, Selma, Zader, Jeannine, Enk, Alexander, Salzmann, Martin, Schäkel, Knut, Winkler, Julia, Wölbing, Priscilla, Asper, Hiba, Bohne, Ann-Sophie, Brown, Victoria, Burba, Bianca, Deffaa, Sophia, Dietrich, Cecilia, Dietrich, Matthias, Drerup, Katharina Antonia, Egberts, Friederike, Erkens, Anna-Sophie, Greven, Salim, Harde, Viola, Kaeding, Merit, Kosova, Katharina, Maagk, Maria, Messinger, Anna Laetitia, Metzner, Malte, Motamedi, Rogina, Rosenthal, Ann-Christine, Seidl, Ulrich, Stemmermann, Jana, Torz, Kaspar, Velez, Juliana Giraldo, Haiduk, Jennifer, Alter, Mareike, Bär, Claudia, Bergenthal, Paul, Gerlach, Anne, Holtorf, Christian, Karoglan, Ante, Kindermann, Sophie, Kraas, Luise, Felcht, Moritz, Gaiser, Maria R., Klemke, Claus-Detlev, Kurzen, Hjalmar, Leibing, Thomas, Müller, Verena, Reinhard, Raphael R., Winter, Franziska, Berking, Carola, Eicher, Laurie, Hartmann, Daniela, Heppt, Markus, Kilian, Katharina, Krammer, Sebastian, Lill, Diana, Niesert, Anne-Charlotte, Oppel, Eva, Sattler, Elke, Senner, Sonja, Wallmichrath, Jens, Wolff, Hans, Gesierich, Anja, Giner, Tina, Glutsch, Valerie, Kerstan, Andreas, Presser, Dagmar, Schrüfer, Philipp, Schummer, Patrick, Stolze, Ina, Weber, Judith, Drexler, Konstantin, Haferkamp, Sebastian, Mickler, Marion, Stauner, Camila Toledo, Thiem, Alexander

“…In recent studies, convolutional neural networks (CNNs) outperformed dermatologists in distinguishing dermoscopic images of melanoma and nevi. In these…”
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Inflammatory markers in autoimmunity induced by checkpoint inhibitors by Husain, Beate, Kirchberger, Michael Constantin, Erdmann, Michael, Schüpferling, Sabine, Abolhassani, Amir-Reza, Fröhlich, Waltraud, Berking, Carola, Heinzerling, Lucie

“…Purpose Immune checkpoint inhibitors (ICI) are highly effective in several cancer entities, but also invoke a variety of immune-related adverse events (irAE)…”
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Spontaneous regression rates of actinic keratosis: a systematic review and pooled analysis of randomized controlled trials by Steeb, Theresa, Petzold, Anne, Hornung, Annkathrin, Wessely, Anja, Berking, Carola, Heppt, Markus V.

“…Actinic keratosis (AK) are precancerous lesions of the skin which may progress to invasive squamous cell carcinoma. However, single lesions may also persist or…”
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General practitioners' perspectives on statutory skin cancer screening-A questionnaire-based cross-sectional survey in Germany by Reinhardt, Lydia, Strasser, Cristin, Steeb, Theresa, Petzold, Anne, Heppt, Markus V, Wessely, Anja, Berking, Carola, Meier, Friedegund

“…In Germany, skin cancer screening (SCS) is available free of charge every two years to all those with statutory health insurance over the age of 35. General…”
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How to MEK the best of uveal melanoma: A systematic review on the efficacy and safety of MEK inhibitors in metastatic or unresectable uveal melanoma by Steeb, Theresa, Wessely, Anja, Ruzicka, Thomas, Heppt, Markus V., Berking, Carola

“…BRAF and MEK inhibitors have demonstrated significant survival benefits for patients with cutaneous melanoma. However, their use for uveal melanoma (UM) is…”
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How Neural Crest Transcription Factors Contribute to Melanoma Heterogeneity, Cellular Plasticity, and Treatment Resistance by Wessely, Anja, Steeb, Theresa, Berking, Carola, Heppt, Markus Vincent

“…Cutaneous melanoma represents one of the deadliest types of skin cancer. The prognosis strongly depends on the disease stage, thus early detection is crucial…”
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The Role of Immune Checkpoint Blockade in Uveal Melanoma by Wessely, Anja, Steeb, Theresa, Erdmann, Michael, Heinzerling, Lucie, Vera, Julio, Schlaak, Max, Berking, Carola, Heppt, Markus Vincent

“…Uveal melanoma (UM) represents the most common intraocular malignancy in adults and accounts for about 5% of all melanomas. Primary disease can be effectively…”
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Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer by Lodygin, Dmitri, Tarasov, Valery, Epanchintsev, Alexey, Berking, Carola, Knyazeva, Tatjana, Körner, Henrike, Knyazev, Piotr, Diebold, Joachim, Hermeking, Heiko

“…Recently, we and others identified the microRNA miR-34a as a target of the tumor suppressor gene product p53. Ectopic miR-34a induces a G1 cell cycle arrest,…”
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Comparing artificial intelligence algorithms to 157 German dermatologists: the melanoma classification benchmark by Brinker, Titus J., Hekler, Achim, Hauschild, Axel, Berking, Carola, Schilling, Bastian, Enk, Alexander H., Haferkamp, Sebastian, Karoglan, Ante, von Kalle, Christof, Weichenthal, Michael, Sattler, Elke, Schadendorf, Dirk, Gaiser, Maria R., Klode, Joachim, Utikal, Jochen S.

“…Several recent publications have demonstrated the use of convolutional neural networks to classify images of melanoma at par with board-certified…”
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Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care by Heppt, Markus V, Siepmann, Timo, Engel, Jutta, Schubert-Fritschle, Gabriele, Eckel, Renate, Mirlach, Laura, Kirchner, Thomas, Jung, Andreas, Gesierich, Anja, Ruzicka, Thomas, Flaig, Michael J, Berking, Carola

“…Hotspot mutations of the oncogenes BRAF and NRAS are the most common genetic alterations in cutaneous melanoma. Specific inhibitors of BRAF and MEK have shown…”
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Immune Checkpoint Blockade in Advanced Cutaneous Squamous Cell Carcinoma: What Do We Currently Know in 2020? by Wessely, Anja, Steeb, Theresa, Leiter, Ulrike, Garbe, Claus, Berking, Carola, Heppt, Markus Vincent

“…Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer that predominantly arises in chronically sun-damaged skin. Immunosuppression,…”
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The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma by Van Allen, Eliezer M, Wagle, Nikhil, Sucker, Antje, Treacy, Daniel J, Johannessen, Cory M, Goetz, Eva M, Place, Chelsea S, Taylor-Weiner, Amaro, Whittaker, Steven, Kryukov, Gregory V, Hodis, Eran, Rosenberg, Mara, McKenna, Aaron, Cibulskis, Kristian, Farlow, Deborah, Zimmer, Lisa, Hillen, Uwe, Gutzmer, Ralf, Goldinger, Simone M, Ugurel, Selma, Gogas, Helen J, Egberts, Friederike, Berking, Carola, Trefzer, Uwe, Loquai, Carmen, Weide, Benjamin, Hassel, Jessica C, Gabriel, Stacey B, Carter, Scott L, Getz, Gad, Garraway, Levi A, Schadendorf, Dirk

“…Most patients with BRAF(V600)-mutant metastatic melanoma develop resistance to selective RAF kinase inhibitors. The spectrum of clinical genetic resistance…”
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MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study by Ascierto, Paolo A, MD, Schadendorf, Dirk, Prof, Berking, Carola, Prof, Agarwala, Sanjiv S, Prof, van Herpen, Carla ML, MD, Queirolo, Paola, MD, Blank, Christian U, MD, Hauschild, Axel, Prof, Beck, J Thaddeus, MD, St-Pierre, Annie, PhD, Niazi, Faiz, MPharm, Wandel, Simon, PhD, Peters, Malte, MD, Zubel, Angela, MD, Dummer, Reinhard, Prof

“…Summary Background Patients with melanoma harbouring Val600 BRAF mutations benefit from treatment with BRAF inhibitors. However, no targeted treatments exist…”
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Case Report: The many faces of bullous pemphigoid by Rechtien, Laura, Sollfrank, Lukas, Foerster, Yannick, Berking, Carola, Sticherling, Michael

“…The pemphigoid group comprises a number of bullous skin diseases with autoantibodies against different constituents of the basement membrane zone that result…”
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Laser-assisted photodynamic therapy for actinic keratosis: A systematic review and meta-analysis by Steeb, Theresa, Schlager, Justin Gabriel, Kohl, Christoph, Ruzicka, Thomas, Heppt, Markus V., Berking, Carola

“…Photodynamic therapy (PDT) is an effective intervention for actinic keratosis and field cancerization. Ablative fractional lasers may facilitate the delivery…”
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The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network by Voskens, Caroline J, Goldinger, Simone M, Loquai, Carmen, Robert, Caroline, Kaehler, Katharina C, Berking, Carola, Bergmann, Tanja, Bockmeyer, Clemens L, Eigentler, Thomas, Fluck, Michael, Garbe, Claus, Gutzmer, Ralf, Grabbe, Stephan, Hauschild, Axel, Hein, Rüdiger, Hundorfean, Gheorghe, Justich, Armin, Keller, Ullrich, Klein, Christina, Mateus, Christine, Mohr, Peter, Paetzold, Sylvie, Satzger, Imke, Schadendorf, Dirk, Schlaeppi, Marc, Schuler, Gerold, Schuler-Thurner, Beatrice, Trefzer, Uwe, Ulrich, Jens, Vaubel, Julia, von Moos, Roger, Weder, Patrik, Wilhelm, Tabea, Göppner, Daniela, Dummer, Reinhard, Heinzerling, Lucie M

“…Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces adverse…”
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Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells by Besch, Robert, Poeck, Hendrik, Hohenauer, Tobias, Senft, Daniela, Häcker, Georg, Berking, Carola, Hornung, Veit, Endres, Stefan, Ruzicka, Thomas, Rothenfusser, Simon, Hartmann, Gunther

“…The retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated antigen 5 (MDA-5) helicases sense viral RNA in infected cells and initiate…”
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