Search Results - "BEREL, Dror"

miR-409-3p/-5p Promotes Tumorigenesis, Epithelial-to-Mesenchymal Transition, and Bone Metastasis of Human Prostate Cancer by JOSSON, Sajni, GURURAJAN, Murali, LICHTERMAN, Jake, NANDANA, Srinivas, QUANLIN LI, ROGATKO, Andre, BEREL, Dror, POSADAS, Edwin M, FAZLI, Ladan, SAREEN, Dhruv, CHUNG, Leland W. K, PEIZHEN HU, CHEN SHAO, CHU, Ginachia-Yi, ZHAU, Haiyen E, CHUNYAN LIU, KAIQIN LAO, LU, Chia-Lun, LU, Yi-Tsung

“…miR-409-3p/-5p is a miRNA expressed by embryonic stem cells, and its role in cancer biology and metastasis is unknown. Our pilot studies demonstrated elevated…”
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A comparison of Ku0063794, a dual mTORC1 and mTORC2 inhibitor, and temsirolimus in preclinical renal cell carcinoma models by Zhang, Hao, Berel, Dror, Wang, Yanping, Li, Ping, Bhowmick, Neil A, Figlin, Robert A, Kim, Hyung L

“…Rapamycin analogs, temsirolimus and everolimus, are approved for the treatment of advance renal cell carcinoma (RCC). Currently approved agents inhibit…”
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Genetic predictors of medically refractory ulcerative colitis by Haritunians, Talin, Taylor, Kent D., Targan, Stephan R., Dubinsky, Marla, Ippoliti, Andrew, Kwon, Soonil, Guo, Xiuqing, Melmed, Gil Y., Berel, Dror, Mengesha, Emebet, Psaty, Bruce M., Glazer, Nicole L., Vasiliauskas, Eric A., Rotter, Jerome I., Fleshner, Phillip R., McGovern, Dermot P.B.

“…Background: Acute severe ulcerative colitis (UC) remains a significant clinical challenge and the ability to predict, at an early stage, those individuals at…”
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ZEB1 regulates glioma stemness through LIF repression by Edwards, Lincoln A., Li, Aiguo, Berel, Dror, Madany, Mecca, Kim, Nam-Ho, Liu, Minzhi, Hymowitz, Mitch, Uy, Benjamin, Jung, Rachel, Xu, Minlin, Black, Keith L., Rentsendorj, Altan, Fan, Xuemo, Zhang, Wei, Yu, John S.

“…The identification of a stem cell regulatory gene which is aberrantly expressed in glioma and associated with patient survival would increase the understanding…”
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TOX3 is expressed in mammary ER(+) epithelial cells and regulates ER target genes in luminal breast cancer by Seksenyan, Akop, Kadavallore, Asha, Walts, Ann E, de la Torre, Brian, Berel, Dror, Strom, Samuel P, Aliahmad, Parinaz, Funari, Vincent A, Kaye, Jonathan

“…A breast cancer susceptibility locus has been mapped to the gene encoding TOX3. Little is known regarding the expression pattern or biological role of TOX3 in…”
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Expression signatures of metastatic capacity in a genetic mouse model of lung adenocarcinoma by Gibbons, Don L, Lin, Wei, Creighton, Chad J, Zheng, Shuling, Berel, Dror, Yang, Yanan, Raso, Maria Gabriela, Liu, Diane D, Wistuba, Ignacio I, Lozano, Guillermina, Kurie, Jonathan M

“…Non-small cell lung cancer (NSCLC) is the foremost cause of cancer-related death in Western countries, which is due partly to the propensity of NSCLC cells to…”
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ZEB1 Is a Transcription Factor That Is Prognostic and Predictive in Diffuse Gliomas by Edwards, Lincoln A, Kim, Sungjin, Madany, Mecca, Nuno, Miriam, Thomas, Tom, Li, Aiguo, Berel, Dror, Lee, Bong-Sup, Liu, Minzhi, Black, Keith L, Fan, Xuemo, Zhang, Wei, Yu, John S

“…To address the unmet medical need to better prognosticate patients with diffuse gliomas and to predict responses to chemotherapy regimens. ZEB1 alterations…”
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Convergent RANK- and c-Met-mediated signaling components predict survival of patients with prostate cancer: an interracial comparative study by Hu, Peizhen, Chung, Leland W K, Berel, Dror, Frierson, Henry F, Yang, Hua, Liu, Chunyan, Wang, Ruoxiang, Li, Qinlong, Rogatko, Andre, Zhau, Haiyen E

“…We reported (PLoS One 6 (12):e28670, 2011) that the activation of c-Met signaling in RANKL-overexpressing bone metastatic LNCaP cell and xenograft models…”
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Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells by Josson, Sajni, Matsuoka, Yasuhiro, Gururajan, Murali, Nomura, Takeo, Huang, Wen-Chin, Yang, Xiaojian, Lin, Jin-Tai, Bridgman, Roger, Chu, Chia-Yi, Johnstone, Peter A, Zayzafoon, Majd, Hu, Peizhen, Zhau, Haiyen, Berel, Dror, Rogatko, Andre, Chung, Leland W K

“…Bone metastasis is the most lethal form of several cancers. The β2-microglobulin (β2-M)/hemochromatosis (HFE) complex plays an important role in cancer…”
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Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens by Gonsky, Rivkah, Deem, Richard L., Landers, Carol J., Derkowski, Carrie A., Berel, Dror, McGovern, Dermot P.B., Targan, Stephan R.

“…Background: High antibody reactivity toward microbial antigens in Crohn's disease (CD) patients is predictive of a more aggressive disease course. However, few…”
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Genomic Profiling of Prostate Cancers from African American Men by Castro, Patricia, Creighton, Chad J., Ozen, Mustafa, Berel, Dror, Mims, Martha P., Ittmann, Michael

“…African American (AA) men have a higher incidence and significantly higher mortality rates from prostate cancer than white men, but the biological basis for…”
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Colorectal cancer screening and surveillance in Crohn's colitis by Basseri, Robert J., Basseri, Benjamin, Vassilaki, Maria E., Melmed, Gil Y., Ippoliti, Andrew, Vasiliauskas, Eric A., Fleshner, Philip R., Lechago, Juan, Hu, Bing, Berel, Dror, Targan, Stephan R., Papadakis, Konstantinos A.

“…To assess colonoscopic screening and surveillance for detecting neoplasia in patients with long-standing colonic Crohn's disease (CD). Colonoscopy and biopsy…”
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The Impact of Preoperative Serum Anti-TNFα Therapy Levels on Early Postoperative Outcomes in Inflammatory Bowel Disease Surgery by Lau, Cheryl, Dubinsky, Marla, Melmed, Gil, Vasiliauskas, Eric, Berel, Dror, McGovern, Dermot, Ippoliti, Andrew, Shih, David, Targan, Stephan, Fleshner, Phillip

“…OBJECTIVE:Assess the impact of preoperative serum antitumor necrosis factor-α (anti-TNFα) drug levels on 30-day postoperative morbidity in inflammatory bowel…”
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A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian Cancer by CHEON, Dong-Joo, YUNGUANG TONG, KARLAN, Beth Y, ORSULIC, Sandra, SIM, Myung-Shin, DERING, Judy, BEREL, Dror, XIAOJIANG CUI, LESTER, Jenny, BEACH, Jessica A, TIGHIOUART, Mourad, WALTS, Ann E

“…To elucidate molecular pathways contributing to metastatic cancer progression and poor clinical outcome in serous ovarian cancer. Poor survival signatures from…”
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Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease by McGovern, Dermot P.B., Jones, Michelle R., Taylor, Kent D., Marciante, Kristin, Yan, Xiaofei, Dubinsky, Marla, Ippoliti, Andy, Vasiliauskas, Eric, Berel, Dror, Derkowski, Carrie, Dutridge, Deb, Fleshner, Phil, Shih, David Q., Melmed, Gil, Mengesha, Emebet, King, Lily, Pressman, Sheila, Haritunians, Talin, Guo, Xiuqing, Targan, Stephan R., Rotter, Jerome I.

“…Genetic variation in both innate and adaptive immune systems is associated with Crohn's disease (CD) susceptibility, but much of the heritability to CD remains…”
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Biomarker signatures of mitochondrial NDUFS3 in invasive breast carcinoma by Suhane, Sonal, Berel, Dror, Ramanujan, V. Krishnan

“…[Display omitted] ► We monitored mitochondrial NDUFS3 expression in clinical breast cancer specimens. ► NDUFS3 expression is significantly higher in highly…”
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Pure Epithelioid PEComas (So-Called Epithelioid Angiomyolipoma) of the Kidney: A Clinicopathologic Study of 41 Cases: Detailed Assessment of Morphology and Risk Stratification by NESE, Nalan, MARTIGNONI, Guido, PEA, Maurizio, AMIN, Mitual B, HES, Ondrej, SVEC, Alexandr, KIDA, Masatoshi, VANKALAKUNTI, Mahesha, BEREL, Dror, ROGATKO, Andre, GOWN, Allen M, AMIN, Mahul B, FLETCHER, Christopher D, GUPTA, Ruta, PAN, Chin-Chan, KIM, Hyung, RO, Jae Y, HWANG, Il S, SATO, Katsuaki, BONETTI, Franco

“…Epithelioid angiomyolipomas (perivascular epithelioid cell tumors) of the kidney are defined as potentially malignant mesenchymal lesions that are closely…”
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A Prospective, Randomized, Noninferiority Trial of Steroid Dosing After Major Colorectal Surgery by Zaghiyan, Karen, Melmed, Gil Y, Berel, Dror, Ovsepyan, Gayane, Murrell, Zuri, Fleshner, Phillip

“…OBJECTIVE:To evaluate the safety of perioperative low-dose steroids (LDS) versus high-dose steroids (HDS) in steroid-treated patients with inflammatory bowel…”
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ZEB1 loss increases glioma stem cell tumorigenicity and resistance to chemoradiation by Hanna, George K, Madany, Mecca, Tay, Angelique Sao-Mai Sy, Edwards, Lincoln A, Kim, Sungjin, Michael, Justin S, Nuno, Miriam, Thomas, Tom, Li, Aiguo, Berel, Dror, Black, Keith L, Fan, Xuemo, Zhang, Wei, Rudnick, Jeremy D, Wang, Rongfu, Yu, John S

“…Glioblastoma has been known to be resistant to chemotherapy and radiation, whereas the underlying mechanisms of resistance have not been fully elucidated. The…”
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Late onset of necrotizing enterocolitis in the full-term infant is associated with increased mortality: Results from a two-center analysis by Short, Scott S, Papillon, Stephanie, Berel, Dror, Ford, Henri R, Frykman, Philip K, Kawaguchi, Akemi

“…Abstract Purpose The effect of timing of onset of necrotizing enterocolitis (NEC) on outcomes has not been determined for the full-term infant. In this study…”
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