Search Results - "BENOIT, Stephen C"

Insulin, leptin, and food reward: update 2008 by Figlewicz, Dianne P, Benoit, Stephen C

“…The hormones insulin and leptin have been demonstrated to act in the central nervous system (CNS) as regulators of energy homeostasis at medial hypothalamic…”
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Gonadal Hormones Determine Sensitivity to Central Leptin and Insulin by CLEGG, Deborah J, BROWN, Lynda M, WOODS, Stephen C, BENOIT, Stephen C

“…Gonadal Hormones Determine Sensitivity to Central Leptin and Insulin Deborah J. Clegg , Lynda M. Brown , Stephen C. Woods and Stephen C. Benoit Department of…”
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Leptin Regulates Energy Balance and Motivation Through Action at Distinct Neural Circuits by Davis, Jon F, Choi, Derrick L, Schurdak, Jennifer D, Fitzgerald, Maureen F, Clegg, Deborah J, Lipton, Jack W, Figlewicz, Dianne P, Benoit, Stephen C

“…Background Overconsumption of calorically dense foods contributes substantially to the current obesity epidemic. The adiposity hormone leptin has been…”
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Consumption of a high-fat diet induces central insulin resistance independent of adiposity by Clegg, Deborah J, Gotoh, Koro, Kemp, Christopher, Wortman, Matthew D, Benoit, Stephen C, Brown, Lynda M, D'Alessio, David, Tso, Patrick, Seeley, Randy J, Woods, Stephen C

“…Abstract Plasma insulin enters the CNS where it interacts with insulin receptors in areas that are related to energy homeostasis and elicits a decrease of food…”
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The central melanocortin system directly controls peripheral lipid metabolism by Nogueiras, Ruben, Wiedmer, Petra, Perez-Tilve, Diego, Veyrat-Durebex, Christelle, Keogh, Julia M, Sutton, Gregory M, Pfluger, Paul T, Castaneda, Tamara R, Neschen, Susanne, Hofmann, Susanna M, Howles, Philip N, Morgan, Donald A, Benoit, Stephen C, Szanto, Ildiko, Schrott, Brigitte, Schürmann, Annette, Joost, Hans-Georg, Hammond, Craig, Hui, David Y, Woods, Stephen C, Rahmouni, Kamal, Butler, Andrew A, Farooqi, I Sadaf, O'Rahilly, Stephen, Rohner-Jeanrenaud, Françoise, Tschöp, Matthias H

“…Disruptions of the melanocortin signaling system have been linked to obesity. We investigated a possible role of the central nervous melanocortin system…”
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Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation by Davidson, Terry L., Chan, Kinho, Jarrard, Leonard E., Kanoski, Scott E., Clegg, Deborah J., Benoit, Stephen C.

“…The effects of selective ibotenate lesions of the complete hippocampus (CHip), the hippocampal ventral pole (VP), or the medial prefrontal cortex (mPFC) in…”
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Ghrelin controls hippocampal spine synapse density and memory performance by Horvath, Tamas L, Diano, Sabrina, Farr, Susan A, Benoit, Stephen C, McNay, Ewan C, da Silva, Ivaldo, Horvath, Balazs, Gaskin, F Spencer, Nonaka, Naoko, Jaeger, Laura B, Banks, William A, Morley, John E, Pinto, Shirly, Sherwin, Robert S, Xu, Lin, Yamada, Kelvin A, Sleeman, Mark W, Tschöp, Matthias H

“…The gut hormone and neuropeptide ghrelin affects energy balance and growth hormone release through hypothalamic action that involves synaptic plasticity in the…”
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Estradiol-Dependent Decrease in the Orexigenic Potency of Ghrelin in Female Rats by CLEGG, Deborah J, BROWN, Lynda M, ZIGMAN, Jeffrey M, KEMP, Christopher J, STRADER, April D, BENOIT, Stephen C, WOODS, Stephen C, MANGIARACINA, Michela, GEARY, Nori

“…Estradiol-Dependent Decrease in the Orexigenic Potency of Ghrelin in Female Rats Deborah J. Clegg 1 , Lynda M. Brown 2 , Jeffrey M. Zigman 3 , Christopher J…”
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Learned and cognitive controls of food intake by Benoit, Stephen C, Davis, Jon F, Davidson, T.L

“…Abstract While much has been elucidated about the hypothalamic controls of energy balance, the epidemic of obesity continues to escalate. Recent work has…”
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Insulin Sensitivity and β-Cell Function Improve after Gastric Bypass in Severely Obese Adolescents by Inge, Thomas H., MD, PhD, Prigeon, Ronald L., MD, Elder, Deborah A., MD, Jenkins, Todd M., PhD, Cohen, Robert M., MD, Xanthakos, Stavra A., MD, MS, Benoit, Stephen C., PhD, Dolan, Lawrence M., MD, Daniels, Stephen R., MD, PhD, D'Alessio, David A., MD

“…Objective To test the hypothesis that insulin secretion and insulin sensitivity would be improved in adolescents after Roux-en-Y gastric bypass (RYGB). Study…”
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Voluntary Exercise Improves High-Fat Diet-Induced Leptin Resistance Independent of Adiposity by Carhuatanta, Kimberly A. Krawczewski, Demuro, Giovanna, Tschöp, Matthias H, Pfluger, Paul T, Benoit, Stephen C, Obici, Silvana

“…The efficacy of exercise as primary prevention of obesity is the subject of intense investigation. Here, we show that voluntary exercise in a mouse strain…”
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A potential role for the hippocampus in energy intake and body weight regulation by Davidson, Terry L, Kanoski, Scott E, Schier, Lindsey A, Clegg, Deborah J, Benoit, Stephen C

“…Recent research and theory point to the possibility that hippocampal-dependent learning and memory mechanisms translate neurohormonal signals of energy balance…”
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Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure by Pfluger, Paul T, Kirchner, Henriette, Günnel, Susanne, Schrott, Brigitte, Perez-Tilve, Diego, Fu, Sheng, Benoit, Stephen C, Horvath, Tamas, Joost, Hans-Georg, Wortley, Katherine E, Sleeman, Mark W, Tschöp, Matthias H

“…Administration of chemically synthesized ghrelin (Ghr) peptide has been shown to increase food intake and body adiposity in most species. However, the…”
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Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice by Brown, Lynda M., Clegg, Deborah J., Benoit, Stephen C., Woods, Stephen C.

“…As the incidence of obesity continues to increase, adequate animal models acquire increased importance for the investigation of energy homeostatic mechanisms…”
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Adiponectin Changes in Relation to the Macronutrient Composition of a Weight-Loss Diet by Summer, Suzanne S., Brehm, Bonnie J., Benoit, Stephen C., D'Alessio, David A.

“…Adiponectin is an adipose‐derived protein with beneficial metabolic effects. Low adiponectin is associated with obesity and related diseases. Significant…”
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Enhanced responsiveness to selective serotonin reuptake inhibitors during lactation by Jury, Nicholas J, McCormick, Betsy A, Horseman, Nelson D, Benoit, Stephen C, Gregerson, Karen A

“…The physiology of mood regulation in the postpartum is poorly understood despite the fact that postpartum depression (PPD) is a common pathology. Serotonergic…”
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Melanocortin signaling in the CNS directly regulates circulating cholesterol by Perez-Tilve, Diego, Hofmann, Susanna M, Basford, Joshua, Nogueiras, Ruben, Pfluger, Paul T, Patterson, James T, Grant, Erin, Wilson-Perez, Hilary E, Granholm, Norman A, Arnold, Myrtha, Trevaskis, James L, Butler, Andrew A, Davidson, William S, Woods, Stephen C, Benoit, Stephen C, Sleeman, Mark W, DiMarchi, Richard D, Hui, David Y, Tschöp, Matthias H

“…This study finds that inhibition of the hypothalamic melanocortin receptors increases the level of high-density lipoprotein HDL-C, a form of cholesterol,…”
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Differential Sensitivity to Central Leptin and Insulin in Male and Female Rats by CLEGG, Deborah J, RIEDY, Christine A, SMITH, Kathleen A, BENOIT, Stephen C, WOODS, Stephen C

“…Differential Sensitivity to Central Leptin and Insulin in Male and Female Rats Deborah J. Clegg 1 , Christine A. Riedy 2 , Kathleen A. Blake Smith 1 , Stephen…”
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The Catabolic Action of Insulin in the Brain Is Mediated by Melanocortins by Benoit, Stephen C, Air, Ellen L, Coolen, Lique M, Strauss, Richelle, Jackman, Alana, Clegg, Deborah J, Seeley, Randy J, Woods, Stephen C

“…Like leptin, the pancreatic hormone insulin is an important adiposity signal to the brain. We report that the hypothalamic melanocortin system is an important…”
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Implication of the melanocortin-3 receptor in the regulation of food intake by Irani, Boman G., Xiang, Zhimin, Yarandi, Hossein N., Holder, Jerry R., Moore, Marcus C., Bauzo, Rayna M., Proneth, Bettina, Shaw, Amanda M., Millard, William J., Chambers, James B., Benoit, Stephen C., Clegg, Deborah J., Haskell-Luevano, Carrie

“…The melanocortin system is well recognized to be involved in the regulation of food intake, body weight, and energy homeostasis. To probe the role of the MC 3…”
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