Search Results - "BENKLİ, Kadriye"

Anti-lung Cancer and Anti-angiogenic Activities of New Designed Boronated Phenylalanine Metal Complexes by Varol, Mehmet, Koparal, Ayse Tansu, Benkli, Kadriye, Bostancioglu, Rakibe Beklem

“…Drug design and discovery studies still remain of great importance in the search for more convenient chemotherapeutic to avoid the drug resistance, systemic…”
Get more information

Synthesis and antituberculosis activity of new thiazolylhydrazone derivatives by Turan-Zitouni, Gülhan, Özdemir, Ahmet, Asim Kaplancikli, Zafer, Benkli, Kadriye, Chevallet, Pierre, Akalin, Gulsen

“…The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and new antimycobacterial…”
Get full text

Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes by Gündoğdu-Karaburun, Nalan, Benkli, Kadriye, Tunali, Yağmur, Uçucu, Ümit, Demirayak, Şeref

“…In this study, some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketones, aryl (3-methyl-benzofuran-2-yl) ketoximes and aryl…”
Get full text

Apoptotic effects of dipyrido [3,2-a:2′,3′-c] phenazine (dppz) Au(III) complex against diethylnitrosamine/phenobarbital induced experimental hepatocarcinogenesis in rats by Tekin, Neslihan, Ustuner, Mehmet C, Akyuz, Fahrettin, Ozbayer, Cansu S, Aydın, Ozlem, Benkli, Kadriye, Burukoglu, Dilek, Degirmenci, Irfan, Ozden, Hilmi

“…We evaluated the effects of dipyrido [3,2-a:2′,3′-c] phenazine (dppz) Au(III) complex ([Au(dppz)Cl₂]Cl) on apoptosis during chemically induced hepatocellular…”
Get full text

The in vitro assessment of dipyridophenazine complexes in H-ras oncogene transformed rat embryo fibroblast 5RP7 cell line by Kaplan, Ayse, Benkli, Kadriye, Koparal, Ayse Tansu

“…Summary Purpose The aim of this study is to detect apoptotic and cytotoxic/antiproliferative effects of a ligand substance and its metal derivatives. The…”
Get full text

Synthesis of Sorafenib−Ruthenium Complexes, Investigation of Biological Activities and Applications in Drug Delivery Systems as an Anticancer Agent by Zengin Kurt, Belma, Öztürk Civelek, Dilek, Çakmak, Elmas Begüm, Kolcuoğlu, Yakup, Şenol, Halil, Sağlık Özkan, Begüm Nurpelin, Dag, Aydan, Benkli, Kadriye

“…Sorafenib, a multiple kinase inhibitor, is widely used as a first-line treatment for hepatocellular carcinoma. However, there is a need for more effective…”
Get full text

Synthesis of new piperazine‐oxadiazole derivatives and investigation of their anticancer activities by Uslu, Harun, Göktaş, Bünyamin, Osmaniye, Derya, Levent, Serkan, Göktaş, Sare Peçe, Sağlık Özkan, Begüm Nurpelin, Özkay, Yusuf, Benkli, Kadriye

“…•10 novel Piperazine-Oxadiazole hybrid derivatives were synthesized.•A good ADME profile were predicted for all the synthesized compounds.•The compound 4b…”
Get full text

Design, synthesis, in vitro, and in silico studies of 1,2,4-triazole-piperazine hybrid derivatives as potential MAO inhibitors by Uslu, Harun, Osmaniye, Derya, Sağlik, Begüm Nurpelin, Levent, Serkan, Özkay, Yusuf, Benkli, Kadriye, Kaplancikli, Zafer Asım

“…[Display omitted] •10 novel 1,2,4-Triazole-Piperazine hybrid derivatives were synthesized.•A good ADME profile were predicted for all the synthesized…”
Get full text

Development of Some Antiplatelet Salts as Drug Active Ingredients and Investigation Biological Activities by Uslu, Harun, Satilmiş, Basri, Uyumlu, Ayşe Burçin, Sağlik, Begüm Nurpelin, Levent, Serkan, Özkay, Yusuf, Genç, Metin Fikret, Batçioğlu, Kadir, Kamişli, Suat, Benkli, Kadriye

“…In this study, prasugrel and prasugrel salts: prasugrel + trans -1,2-cyclohexanedicarboxylic acid ( 1a ), prasugrel + maleic acid ( 2a ), prasugrel + citric…”
Get full text

Gold(III) compounds-mediated inhibition of lung cancer cell line proliferation: potential apoptotic effects for its chemotherapeutic effects by Bostancoğlu, Rakibe B, Kaya, Murat, Koparal, Ayşe T, Benkli, Kadriye

“…Research on chemotherapeutics for lung cancer is crucial for designing a new therapeutic strategy against malignant lung tumors. Although radiotherapy and…”
Get full text

Design and synthesis of novel organometallic complexes using boronated phenylalanine derivatives as potential anticancer agents by Varol, Mehmet, Benkli, Kadriye, Koparal, Ayşe T., Bostancıoğlu, Rakibe B.

“…Drug design and discovery studies are important because of the prevalence of diseases without available medical cures. New anticancer agents are particularly…”
Get full text

Assessment of in vitro cytotoxic and genotoxic activities of some trimethoprim conjugates by Güzel Bayülken, Devrim, Bostancıoğlu, R. Beklem, Koparal, A. Tansu, Ayaz Tüylü, Berrin, Dağ, Aydan, Benkli, Kadriye

“…Trimethoprim, a commonly used antibacterial agent, is widely applied in the treatment of variety of infections in human. A few studies have demonstrated an…”
Get full text

Gold(III) compounds-mediated inhibition of lung cancer cell proliferation by Bostancioğlu, Rakibe B, Kaya, Murat, Koparal, Ayşe T, Benkli, Kadriye

“…Research on chemotherapeutics for lung cancer is crucial for designing a new therapeutic strategy against malignant lung tumors. Although radiotherapy and…”
Get full text

Erratum to: Antibacterial and antifungal activities of some trimethoprim salts by Tunali, Yağmur, Karaca, Hulya, Benkli, Kadriye

Get full text

Investigation of the pharmacological profiles of dinuclear metal complexes as novel, potent and selective cytotoxic agents against ras -transformed cells by Bostancıoğlu, R. Beklem, Koparal, A. Tansu, Benkli, Kadriye

“…Graphical abstract…”
Get full text

Studies on the cytotoxic, apoptotic and antitumoral effects of Au(III) and Pt(II) complexes of 1, 10-phenanthroline on V79 379A and A549 cell lines by Bostancıoğlu, R Beklem, Işık, Kenan, Genç, Hatice, Benkli, Kadriye, Koparal, Ayşe Tansu

“…In the present study, Au(III) and Pt(II) complexes of 1, 10-phenanthroline (phen) were synthesized and used as the test compounds. The structure elucidation of…”
Get more information

Biological activities of Cu(II) and Hg(II) complexes of a heptadentate Schiff base ligand by ERGENE, EMEL, SİVAS, HÜLYA, BENKLİ, KADRİYE

“…İki metal bileşiği, [Hg(L)]($ClO _4) _2$ve [Cu(L)]($ClO _4) _2$, Hg(II) ve Cu(II) perchlorate tuzlarının varlığında, 2,6-bis(2- aminothiophenoxymethyl)pyridine…”
Get full text

Cytotoxic and genotoxic effects of [Ru(phi) 3] 2+ evaluated by Ames/ Salmonella and MTT methods by Benkli, Kadriye, Tunali, Yağmur, Cantürk, Zerrin, Artagan, Öge, Alanyali, Filiz

“…In this work, we synthesized and evaluated the cytotoxic effect of [Ru(phi) 3] 2+, on rat C6 glioma cell line. Cell viability was determined by assay with…”
Get full text

Antibacterial and antifungal activities of some trimethoprim salts by Tunalı, Yağmur, Karaca, Hülya, İşcan, Gökalp, Demirci, Fatih, Benkli, Kadriye

“…In this study, the antimicrobial activities of Trimethoprim (1), Trimethoprim + Maleic acid (2), Trimethoprim + Oxalic acid dihydrate (3), and Trimethoprim + …”
Get full text

Synthesis and Characterization of New Binaphthyl-Linked Phenanthroline-, Bipyridine-, or Pyridine-Derived Ligands, and the Study of Their Cytotoxic Activity by Beynek, Nesrin, Uluçam, Gühergül, Benkli, Kadriye, Koparal, Ays̨e Tansu

“…In the present work, we describe the synthesis and characterization of five new versatile acyclic or macrocyclic ligands containing binaphthyl‐linked pyridine,…”
Get full text