Search Results - "BENICHOU, Gilles"

Allorecognition by T Lymphocytes and Allograft Rejection by Marino, Jose, Paster, Joshua, Benichou, Gilles

“…Recognition of donor antigens by recipient T cells in secondary lymphoid organs initiates the adaptive inflammatory immune response leading to the rejection of…”
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Intercellular transfer of MHC molecules in T cell alloimmunity and allotransplantation by Benichou, Gilles, Lancia, Hyshem H

“…After transplantation of allogeneic tissues and organs, recognition by recipient T cells of donor MHC molecules initiates the pro-inflammatory adaptive immune…”
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Tolerance of a Vascularized Composite Allograft Achieved in MHC Class-I-mismatch Swine via Mixed Chimerism by Lellouch, Alexandre G, Andrews, Alec R, Saviane, Gaelle, Ng, Zhi Yang, Schol, Ilse M, Goutard, Marion, Gama, Amon-Ra, Rosales, Ivy A, Colvin, Robert B, Lantieri, Laurent A, Randolph, Mark A, Benichou, Gilles, Cetrulo, Jr, Curtis L

“…Vascularized composite allografts (VCAs) allow reconstruction of devastating injuries and amputations, yet require lifelong immunosuppression that is…”
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Early Acceptance of Renal Allografts in Mice Is Dependent on Foxp3+ Cells by Miyajima, Masahiro, Chase, Catharine M, Alessandrini, Alessandro, Farkash, Evan A, Della Pelle, Patricia, Benichou, Gilles, Graham, Jay A, Madsen, Joren C, Russell, Paul S, Colvin, Robert B

“…Mouse renal allografts have a remarkable ability to promote acceptance across full major histocompatibility complex incompatibilities in certain strain…”
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Natural killer cells in rejection and tolerance of solid organ allografts by Benichou, Gilles, Yamada, Yohei, Aoyama, Akihiro, Madsen, Joren C

“…A series of recent studies defy conventional wisdom by showing that natural killer (NK) cells exert a powerful and long-lasting influence on the immune…”
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Differential Roles of Direct and Indirect Allorecognition Pathways in the Rejection of Skin and Corneal Transplants by BOISGERAULT, Florence, YING LIU, ANOSOVA, Nathalie, DANA, Reza, BENICHOU, Gilles

“…It is generally accepted that all transplants are not rejected in the same fashion. However, the extrinsic and intrinsic factors that control the recognition…”
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TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells by Cherbonneau, François, Li, Guoping, Gokulnath, Priyanka, Sahu, Parul, Prunevieille, Aurore, Kitchen, Robert, Benichou, Gilles, Larghero, Jérôme, Domian, Ibrahim, Das, Saumya

“…Dynamic profiling of changes in gene expression in response to stressors in specific microenvironments without requiring cellular destruction remains…”
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Relevance of the Direct Pathway of Sensitization in Corneal Transplantation Is Dictated by the Graft Bed Microenvironment by Huq, Syed, Liu, Ying, Benichou, Gilles, Dana, M. Reza

“…Corneal grafts were until recently considered entirely devoid of resident APCs, giving rise to the tenet that alloantigen recognition is mediated exclusively…”
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High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry by Lechene, Claude, Hillion, Francois, McMahon, Greg, Benson, Douglas, Kleinfeld, Alan M, Kampf, J Patrick, Distel, Daniel, Luyten, Yvette, Bonventre, Joseph, Hentschel, Dirk, Park, Kwon Moo, Ito, Susumu, Schwartz, Martin, Benichou, Gilles, Slodzian, Georges

“…Secondary-ion mass spectrometry (SIMS) is an important tool for investigating isotopic composition in the chemical and materials sciences, but its use in…”
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Intracellular MHC Class II Controls Regulatory Tolerance to Allogeneic Transplants by LeGuern, Christian, Akiyama, Yoshinobu, Germana, Sharon, Tanaka, Katsunori, Fernandez, Luis, Iwamoto, Yoshiko, Houser, Stuart, Benichou, Gilles

“…MHC class II (MHCII) genes have been implicated in the regulation of T lymphocyte responses. However, the mechanism of MHCII-driven regulation remains unknown…”
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Bidirectional alloreactivity: A proposed microchimerism-based solution to the NIMA paradox by Burlingham, William J., Benichou, Gilles

“…The NIMA paradox is the observation that in transplants of allogeneic kidneys or hematopoietic stem cells, siblings benefit from re-exposure to non-inherited…”
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A Mixed-chimerism Protocol Utilizing Thymoglobulin and Belatacept Did Not Induce Lung Allograft Tolerance, Despite Previous Success in Renal Allotransplantation by Sommer, Wiebke, O, Jane M., Pruner, Kurt B., Dehnadi, Abbas, Ha Huh, Kyu, Robinson, Kortney A., Hanekamp, Isabel, Rosales, Ivy, Bean, Alison S., Paster, Josh, Oura, Tetsu, Neal Smith, Rex, Colvin, Robert, Benichou, Gilles, Kawai, Tatsuo, Madsen, Joren C., Allan, James S.

“…In kidney transplantation, long-term allograft acceptance in cynomolgus macaques was achieved using a mixed-chimerism protocol based on the clinically…”
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Abstract 51: Tolerance Induction Protocol For VCA Across Full Mismatch Barriers In MHC-Defined Miniature Swine by Andrews, Alec R., Tratnig-Frankl, Philipp, Taveau, Corentin B., Jonczyk, Michael M., Lantieri, Laurent A., Randolph, Mark A., Lellouch, Alexandre G., Benichou, Gilles, Cetrulo, Curtis L.

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Abstract 68: Tolerance Induction of Vascularized Composite Allografts Across a Class I Barrier in Swine by Lellouch, Alexandre G., Saviane, Gaelle, Burlage, Laura C., Schol, Ilse M., Lantieri, Laurent A., Randolph, Mark A., Benichou, Gilles, Cetrulo, Curtis L.

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Effects of an agonist interleukin-2/Fc fusion protein, a mutant antagonist interleukin-15/Fc fusion protein, and sirolimus on cardiac allograft survival in non-human primates by Millington, Timothy, MD, Koulmanda, Maria, PhD, Ng, Choo, MD, Boskovic, Svjetlan, MD, Nadazdin, Ognjenka M., MD, Benichou, Gilles, PhD, Zheng, Xin Xiao, MD, Strom, Terry B., MD, Madsen, Joren C., MD, PhD

“…Background To tilt the immunologic balance toward tolerance and away from rejection, non-human primate recipients of cardiac allografts were treated with…”
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Tolerance to Noninherited Maternal MHC Antigens in Mice by Andrassy, Joachim, Kusaka, Satoshi, Jankowska-Gan, Ewa, Torrealba, Jose R, Haynes, Lynn D, Marthaler, Brodie R, Tam, Robert C, Illigens, Ben M.-W, Anosova, Natalie, Benichou, Gilles, Burlingham, William J

“…The phenomenon of tolerance to noninherited maternal Ags (NIMA) is poorly understood. To analyze the NIMA effect C57BL/6 (H-2(b/b)) males were mated with…”
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Renal allograft tolerance can be achieved in non-human primates via delayed mixed-hematopoietic chimerism and alefacept treatment by Lee, Soyoung, MD, Yamada, Yohei, MD, Tonsho, Makoto, MD, Boskovic, Svjetlan, MD, Smith, Rex Neal, MD, Colvin, Robert B., MD, Madsen, Joren C., MD, PhD, FACS, Cosimi, A. Benedict, MD, FACS, Benichou, Gilles, MD, Kawai, Tatsuo, MD, FACS

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Lung allograft tolerance in non-human primates following delayed donor bone marrow transplantation by Lee, Soyoung, MD, FRCSG, Aoyama, Akihiro, MD, Tonsho, Makoto, MD, Boskovic, Svjetlan, MD, Smith, Rex Neal, MD, Cosimi, A. Benedict, MD, FACS, Madsen, Joren C., MD, PhD, FACS, Benichou, Gilles, MD, Kawai, Tatsuo, MD, FACS, Allan, James S., MD, FACS

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Autoimmune Sensitization to Cardiac Myosin Leads to Acute Rejection of Cardiac Allografts in Miniature Swine by VEILLETTE, Gregory R, SAHARA, Hisashi, BENICHOU, Gilles, MADSEN, Joren C, MELTZER, Andrew J, WEISS, Mathew J, IWAMOTO, Yoshiko, KIM, Karen M, ROSENGARD, Bruce R, ALLAN, James S, HOUSER, Stuart L, SACHS, David H

“…Recent studies in mice and patients suggest that posttransplantation induction of autoimmune responses to tissue-specific antigens contributes to the rejection…”
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Anti-IL-6R antibodies prevent acute rejection of allogeneic lung transplants in monkeys by Lee, Soyoung, MD, Aoyama, Akihiro, MD, Tonsho, Makoto, MD, Boskovic, Svjetlan, MD, Yamada, Yohei, MD, Cosimi, A. Benedict, MD, Madsen, Joren C., MD, PhD, Benichou, Gilles, MD, Kawai, Tatsuo, MD, Allan, James S., MD, FACS

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