Search Results - "BEN ABDELALI, Raouf"

Toward a NOTCH1/FBXW7/RAS/PTEN–Based Oncogenetic Risk Classification of Adult T-Cell Acute Lymphoblastic Leukemia: A Group for Research in Adult Acute Lymphoblastic Leukemia Study by TRINQUAND, Amélie, TANGUY-SCHMIDT, Aline, LHERITIER, Véronique, BOND, Jonathan, HUGUET, Françoise, BUZYN, Agnès, LEGUAY, Thibaud, CAHN, Jean-Yves, THOMAS, Xavier, CHALANDON, Yves, DELANNOY, André, BONMATI, Caroline, BEN ABDELALI, Raouf, MAURY, Sebastien, NADEL, Bertrand, MACINTYRE, Elizabeth, IFRAH, Norbert, DOMBRET, Hervé, ASNAFI, Vahid, LAMBERT, Jérôme, BELDJORD, Kheira, LENGLINE, Etienne, DE GUNZBURG, Noémie, PAYET-BORNET, Dominique, LHERMITTE, Ludovic, MOSSAFA, Hossein

“…The Group for Research in Adult Acute Lymphoblastic Leukemia (GRAALL) recently reported a significantly better outcome in T-cell acute lymphoblastic leukemia…”
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A randomized phase II trial of azacitidine +/- epoetin-β in lower-risk myelodysplastic syndromes resistant to erythropoietic stimulating agents by Thépot, Sylvain, Ben Abdelali, Raouf, Chevret, Sylvie, Renneville, Aline, Beyne-Rauzy, Odile, Prébet, Thomas, Park, Sophie, Stamatoullas, Aspasia, Guerci-Bresler, Agnes, Cheze, Stéphane, Tertian, Gérard, Choufi, Bachra, Legros, Laurence, Bastié, Jean Noel, Delaunay, Jacques, Chaury, Marie Pierre, Sanhes, Laurence, Wattel, Eric, Dreyfus, Francois, Vey, Norbert, Chermat, Fatiha, Preudhomme, Claude, Fenaux, Pierre, Gardin, Claude

“…The efficacy of azacitidine in patients with anemia and with lower-risk myelodysplastic syndromes, if relapsing after or resistant to erythropoietic…”
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Technical Validation of a Reverse-Transcription Quantitative Polymerase Chain Reaction In Vitro Diagnostic Test for the Determination of MiR-31-3p Expression Levels in Formalin-Fixed Paraffin-Embedded Metastatic Colorectal Cancer Tumor Specimens by Ramon, Lucas, David, Catherine, Fontaine, Karine, Lallet, Elodie, Marcaillou, Charles, Martin-Lannerée, Séverine, Decaulne, Virginie, Vazart, Céline, Gélibert, Anne-Héloise, Abdelali, Raouf Ben, Costa, Jean-Marc, Rousseau, Francis, Thiébaut, Raphaële, Yost, Larry, Gaston-Mathé, Yann

“…MiR-31-3p expression has been shown to be a predictive biomarker for response to anti-epithelial growth factor receptor therapy in patients with RAS wild-type…”
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Impact of additional genetic alterations on the outcome of patients with NPM1-mutated cytogenetically normal acute myeloid leukemia by Peterlin, Pierre, Renneville, Aline, Ben Abdelali, Raouf, Nibourel, Olivier, Thomas, Xavier, Pautas, Cécile, de Botton, Stéphane, Raffoux, Emmanuel, Cayuela, Jean-Michel, Boissel, Nicolas, Terré, Christine, Celli-Lebras, Karine, Castaigne, Sylvie, Preudhomme, Claude, Gardin, Claude, Dombret, Hervé

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ALL-associated JAK1 mutations confer hypersensitivity to the antiproliferative effect of type I interferon by Hornakova, Tekla, Chiaretti, Sabina, Lemaire, Muriel M., Foà, Robin, Ben Abdelali, Raouf, Asnafi, Vahid, Tartaglia, Marco, Renauld, Jean-Christophe, Knoops, Laurent

“…Activating mutations in JAK1 have been reported in acute lymphoblastic leukemias (ALLs). In this study, we found a type I interferon (IFN) transcriptional…”
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Cartridge-based automated BCR-ABL1 mRNA quantification: solving the issues of standardization, at what cost? by CAYUELA, Jean-Michel, MACINTYRE, Elizabeth, SEROR, Valerie, DARLINGTON, Meryl, ABDELALI, Raouf Ben, FUND, Xavier, VILLARESE, Patrick, TULLIEZ, Michel, RAFFOUX, Emmanuel, SIGAUX, François, REA, Delphine

“…Molecular monitoring of chronic myeloid leukemia patients treated with tyrosine kinase inhibitors is essential for therapeutic stratification. Inter-laboratory…”
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Epidemiology, clinical picture and long‐term outcomes of FIP1L1‐PDGFRA‐positive myeloid neoplasm with eosinophilia: Data from 151 patients by Rohmer, Julien, Couteau‐Chardon, Amélie, Trichereau, Julie, Panel, Kewin, Gesquiere, Cyrielle, Ben Abdelali, Raouf, Bidet, Audrey, Bladé, Jean‐Sébastien, Cayuela, Jean‐Michel, Cony‐Makhoul, Pascale, Cottin, Vincent, Delabesse, Eric, Ebbo, Mikaël, Fain, Olivier, Flandrin, Pascale, Galicier, Lionel, Godon, Catherine, Grardel, Nathalie, Guffroy, Aurélien, Hamidou, Mohamed, Hunault, Mathilde, Lengline, Etienne, Lhomme, Faustine, Lhermitte, Ludovic, Machelart, Irène, Mauvieux, Laurent, Mohr, Catherine, Mozicconacci, Marie‐Joelle, Naguib, Dina, Nicolini, Franck E., Rey, Jerome, Rousselot, Philippe, Tavitian, Suzanne, Terriou, Louis, Lefèvre, Guillaume, Preudhomme, Claude, Kahn, Jean‐Emmanuel, Groh, Matthieu

“…FIP1L1‐PDGFRA‐positive myeloid neoplasm with eosinophilia (F/P+ MN‐eo) is a rare disease: robust epidemiological data are lacking and reported issues are…”
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Clinical Impact of NOTCH1 and/or FBXW7 Mutations, FLASH Deletion, and TCR Status in Pediatric T-Cell Lymphoblastic Lymphoma by CALLENS, Celine, BALEYDIER, Frederic, BARUCHEL, André, SCHMITT, Claudine, ASNAFI, Vahid, BERTRAND, Yves, MACINTYRE, Elizabeth, LENGLINE, Etienne, BEN ABDELALI, Raouf, PETIT, Arnaud, VILLARESE, Patrick, CIESLAK, Agata, MINARD-COLIN, Veronique, RULLIER, Anne, MOREAU, Anne

“…Pediatric T-cell lymphoblastic lymphomas (T-LBL) are commonly treated on T-cell acute lymphoblastic leukemia (T-ALL) -derived protocols. Therapeutic…”
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SET-NUP214 is a recurrent γδ lineage-specific fusion transcript associated with corticosteroid/chemotherapy resistance in adult T-ALL by Ben Abdelali, Raouf, Roggy, Anne, Leguay, Thibaut, Cieslak, Agata, Renneville, Aline, Touzart, Aurore, Banos, Anne, Randriamalala, Edouard, Caillot, Denis, Lioure, Bruno, Devidas, Alain, Mossafa, Hossein, Preudhomme, Claude, Ifrah, Norbert, Dombret, Hervé, Macintyre, Elizabeth, Asnafi, Vahid

“…The SET-NUP214 (TAF1/CAN) fusion gene is a rare genetic event in T-cell acute lymphoblastic leukemia (T-ALL). Eleven (6%) of 196 T-ALL patients enrolled in the…”
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Genomic analysis of primary and secondary myelofibrosis redefines the prognostic impact of ASXL1 mutations: a FIM study by Luque Paz, Damien, Riou, Jérémie, Verger, Emmanuelle, Cassinat, Bruno, Chauveau, Aurélie, Ianotto, Jean-Christophe, Dupriez, Brigitte, Boyer, Françoise, Renard, Maxime, Mansier, Olivier, Murati, Anne, Rey, Jérôme, Etienne, Gabriel, Mansat-De Mas, Véronique, Tavitian, Suzanne, Nibourel, Olivier, Girault, Stéphane, Le Bris, Yannick, Girodon, François, Ranta, Dana, Chomel, Jean-Claude, Cony-Makhoul, Pascale, Sujobert, Pierre, Robles, Margot, Ben Abdelali, Raouf, Kosmider, Olivier, Cottin, Laurane, Roy, Lydia, Sloma, Ivan, Vacheret, Fabienne, Wemeau, Mathieu, Mossuz, Pascal, Slama, Borhane, Cussac, Vincent, Denis, Guillaume, Walter-Petrich, Anouk, Burroni, Barbara, Jézéquel, Nathalie, Giraudier, Stéphane, Lippert, Eric, Socié, Gérard, Kiladjian, Jean-Jacques, Ugo, Valérie

“…We aimed to study the prognostic impact of the mutational landscape in primary and secondary myelofibrosis. The study included 479 patients with myelofibrosis…”
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Granulomonocytic progenitors are key target cells of azacytidine in higher risk myelodysplastic syndromes and acute myeloid leukemia by Ali, Ashfaq, Penneroux, Justine, Dal Bello, Reinaldo, Massé, Aline, Quentin, Samuel, Unnikrishnan, Ashwin, Hernandez, Lucie, Raffoux, Emmanuel, Ben Abdelali, Raouf, Renneville, Aline, Preudhomme, Claude, Pimanda, John, Dombret, Hervé, Soulier, Jean, Fenaux, Pierre, Clappier, Emmanuelle, Adès, Lionel, Puissant, Alexandre, Itzykson, Raphael

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Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial by Renneville, Aline, Abdelali, Raouf Ben, Chevret, Sylvie, Nibourel, Olivier, Cheok, Meyling, Pautas, Cécile, Duléry, Rémy, Boyer, Thomas, Cayuela, Jean-Michel, Hayette, Sandrine, Raffoux, Emmanuel, Farhat, Hassan, Boissel, Nicolas, Terre, Christine, Dombret, Hervé, Castaigne, Sylvie, Preudhomme, Claude

“…We recently showed that the addition of fractionated doses of gemtuzumab ozogamicin (GO) to standard chemotherapy improves clinical outcome of acute myeloid…”
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Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/FBXW7 mutations, but not of low ERG/BAALC expression: a GRAALL study by Ben Abdelali, Raouf, Asnafi, Vahid, Leguay, Thibaut, Boissel, Nicolas, Buzyn, Agnès, Chevallier, Patrice, Thomas, Xavier, Lepretre, Stephane, Huguet, Françoise, Vey, Norbert, Escoffre-Barbe, Martine, Tavernier, Emmanuelle, Reman, Oumedaly, Fegueux, Nathalie, Turlure, Pascal, Rousselot, Philippe, Cahn, Jean-Yves, Lheritier, Veronique, Chalandon, Yves, Béné, Marie-Christine, Macintyre, Elizabeth, Dombret, Hervé, Ifrah, Norbert

“…Despite recent progress in the understanding of acute lymphoblastic leukemia (T-ALL) oncogenesis, few markers are sufficiently frequent in large subgroups to…”
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The prognosis of CALM-AF10-positive adult T-cell acute lymphoblastic leukemias depends on the stage of maturation arrest by Ben Abdelali, Raouf, Asnafi, Vahid, Petit, Arnaud, Micol, Jean-Baptiste, Callens, Céline, Villarese, Patrick, Delabesse, Eric, Reman, Oumedaly, Lepretre, Stephane, Cahn, Jean-Yves, Guillerm, Gaelle, Berthon, Céline, Gardin, Claude, Corront, Bernadette, Leguay, Thibaut, Béné, Marie-Christine, Ifrah, Norbert, Leverger, Guy, Dombret, Hervé, Macintyre, Elizabeth

“…CALM-AF10 (also known as PICALM-MLLT10) is the commonest fusion protein in T-cell acute lymphoblastic leukemia, but its prognostic impact remains unclear…”
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Extensive molecular mapping of TCRα/δ- and TCRβ-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL by Le Noir, Sandrine, Ben Abdelali, Raouf, Lelorch, Marc, Bergeron, Julie, Sungalee, Stephanie, Payet-Bornet, Dominique, Villarèse, Patrick, Petit, Arnaud, Callens, Céline, Lhermitte, Ludovic, Baranger, Laurence, Radford-Weiss, Isabelle, Grégoire, Marie-José, Dombret, Hervé, Ifrah, Norbert, Spicuglia, Salvatore, Romana, Serge, Soulier, Jean, Nadel, Bertrand, Macintyre, Elizabeth, Asnafi, Vahid

“…Chromosomal translocations involving the TCR loci represent one of the most recurrent oncogenic hallmarks of T-cell acute lymphoblastic leukemia (T-ALL) and…”
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C/EBPA methylation is common in T-ALL but not in M0 AML by Terriou, Louis, Ben Abdelali, Raouf, Roumier, Christophe, Lhermitte, Ludovic, de Vos, John, Cornillet, Pascale, Nibourel, Olivier, Beldjord, Kheira, Dombret, Hervé, Leverger, Guy, Asnafi, Vahid, Preudhomme, Claude, Macintyre, Elizabeth

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Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia by Sebert, Marie, Gachet, Stéphanie, Leblanc, Thierry, Rousseau, Alix, Bluteau, Olivier, Kim, Rathana, Ben Abdelali, Raouf, Sicre de Fontbrune, Flore, Maillard, Loïc, Fedronie, Carèle, Murigneux, Valentine, Bellenger, Léa, Naouar, Naira, Quentin, Samuel, Hernandez, Lucie, Vasquez, Nadia, Da Costa, Mélanie, Prata, Pedro H., Larcher, Lise, de Tersant, Marie, Duchmann, Matthieu, Raimbault, Anna, Trimoreau, Franck, Fenneteau, Odile, Cuccuini, Wendy, Gachard, Nathalie, Auger, Nathalie, Tueur, Giulia, Blanluet, Maud, Gazin, Claude, Souyri, Michèle, Langa Vives, Francina, Mendez-Bermudez, Aaron, Lapillonne, Hélène, Lengline, Etienne, Raffoux, Emmanuel, Fenaux, Pierre, Adès, Lionel, Forcade, Edouard, Jubert, Charlotte, Domenech, Carine, Strullu, Marion, Bruno, Bénédicte, Buchbinder, Nimrod, Thomas, Caroline, Petit, Arnaud, Leverger, Guy, Michel, Gérard, Cavazzana, Marina, Gluckman, Eliane, Bertrand, Yves, Boissel, Nicolas, Baruchel, André, Dalle, Jean-Hugues, Clappier, Emmanuelle, Gilson, Eric, Deriano, Ludovic, Chevret, Sylvie, Sigaux, François, Socié, Gérard, Stoppa-Lyonnet, Dominique, de Thé, Hugues, Antoniewski, Christophe, Bluteau, Dominique, Peffault de Latour, Régis, Soulier, Jean

“…Fanconi anemia (FA) patients experience chromosome instability, yielding hematopoietic stem/progenitor cell (HSPC) exhaustion and predisposition to…”
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Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia by Malinge, Sebastien, Ben-Abdelali, Raouf, Settegrana, Catherine, Radford-Weiss, Isabelle, Debre, Marianne, Beldjord, Kheira, Macintyre, Elizabeth A., Villeval, Jean-Luc, Vainchenker, William, Berger, Roland, Bernard, Olivier A., Delabesse, Eric, Penard-Lacronique, Virginie

“…Activation of tyrosine kinase genes is a frequent event in human hematologic malignancies. Because gene activation could be associated with gene dysregulation,…”
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Value of EVI1 Gene Expression Level in Adult Acute Lymphoblastic Leukemia (ALL): A Study from the Group for Research on Adult ALL (GRAALL) by Abbal, Claire, Ben Abdelali, Raouf, Lafage, Marina, Huguet, Françoise, Leguay, Thibaut, Spertini, Olivier, Boissel, Nicolas, Gardin, Claude, Graux, Carlos, Cayuela, Jean-Michel, Boulland, Marie-Laure, Grardel, Nathalie, Bouvier, Anne, Duchosal, Michel, Lhéritier, Véronique, Chalandon, Yves, Asnafi, Vahid, Ifrah, Norbert, Dombret, Hervé

“…Background:EVI1 gene overexpression is found in approximately 10% of acute myeloid leukemia (AML) patients, with a higher frequency seen in AML carrying…”
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Heterogeneity Of Patients With Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) and Nucleophosmin-1 (NPM1) Gene Mutation: An Acute Leukemia French Association (ALFA) Study by Peterlin, Pierre, Renneville, Aline, Ben Abdelali, Raouf, Nibourel, Olivier, Thomas, Xavier, Pautas, Cécile, de Botton, Stéphane, Gardin, Claude, Raffoux, Emmanuel, Cayuela, Jean-Michel, Boissel, Nicolas, Terré, Christine, Celli-Lebras, Karine, Castaigne, Sylvie, Preudhomme, Claude, Dombret, Hervé

“…▪ CN-AML with NPM1 mutation accounts for 25% of AML cases and is individualized as a provisional entity in the WHO classification. In this large AML subset,…”
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