Search Results - "BELLOSILLO, Beatriz"

Effect of Mutation Order on Myeloproliferative Neoplasms by Ortmann, Christina A, Kent, David G, Nangalia, Jyoti, Silber, Yvonne, Wedge, David C, Grinfeld, Jacob, Baxter, E. Joanna, Massie, Charles E, Papaemmanuil, Elli, Menon, Suraj, Godfrey, Anna L, Dimitropoulou, Danai, Guglielmelli, Paola, Bellosillo, Beatriz, Besses, Carles, Döhner, Konstanze, Harrison, Claire N, Vassiliou, George S, Vannucchi, Alessandro, Campbell, Peter J, Green, Anthony R

“…About 10% of myeloproliferative neoplasms carry mutations in both TET2 and JAK2 . Clinical presentation, risk of thrombosis, and rates of tumor progression are…”
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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients by Siravegna, Giulia, Mussolin, Benedetta, Buscarino, Michela, Corti, Giorgio, Cassingena, Andrea, Crisafulli, Giovanni, Ponzetti, Agostino, Cremolini, Chiara, Amatu, Alessio, Lauricella, Calogero, Lamba, Simona, Hobor, Sebastijan, Avallone, Antonio, Valtorta, Emanuele, Rospo, Giuseppe, Medico, Enzo, Motta, Valentina, Antoniotti, Carlotta, Tatangelo, Fabiana, Bellosillo, Beatriz, Veronese, Silvio, Budillon, Alfredo, Montagut, Clara, Racca, Patrizia, Marsoni, Silvia, Falcone, Alfredo, Corcoran, Ryan B, Di Nicolantonio, Federica, Loupakis, Fotios, Siena, Salvatore, Sartore-Bianchi, Andrea, Bardelli, Alberto

“…By monitoring ctDNA, the authors reveal the dynamic adaption of clonal populations in colorectal cancer patients treated with anti-EGFR therapy, suggesting…”
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p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis by Solé, Laura, Lobo-Jarne, Teresa, Álvarez-Villanueva, Daniel, Alonso-Marañón, Josune, Guillén, Yolanda, Guix, Marta, Sangrador, Irene, Rozalén, Catalina, Vert, Anna, Barbachano, Antonio, Lop, Joan, Salido, Marta, Bellosillo, Beatriz, García-Romero, Raquel, Garrido, Marta, González, Jessica, Martínez-Iniesta, María, López-Arribillaga, Erika, Salazar, Ramón, Montagut, Clara, Torres, Ferrán, Iglesias, Mar, Celià-Terrassa, Toni, Muñoz, Alberto, Villanueva, Alberto, Bigas, Anna, Espinosa, Lluís

“…Current therapy against colorectal cancer (CRC) is based on DNA-damaging agents that remain ineffective in a proportion of patients. Whether and how…”
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Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer by Arena, Sabrina, Bellosillo, Beatriz, Siravegna, Giulia, Martínez, Alejandro, Cañadas, Israel, Lazzari, Luca, Ferruz, Noelia, Russo, Mariangela, Misale, Sandra, González, Iria, Iglesias, Mar, Gavilan, Elena, Corti, Giorgio, Hobor, Sebastijan, Crisafulli, Giovanni, Salido, Marta, Sánchez, Juan, Dalmases, Alba, Bellmunt, Joaquim, De Fabritiis, Gianni, Rovira, Ana, Di Nicolantonio, Federica, Albanell, Joan, Bardelli, Alberto, Montagut, Clara

“…Patients with colorectal cancer who respond to the anti-EGFR antibody cetuximab often develop resistance within several months of initiating therapy. To design…”
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Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer by Montagut, Clara, Dalmases, Alba, Bellosillo, Beatriz, Crespo, Marta, Pairet, Silvia, Iglesias, Mar, Salido, Marta, Gallen, Manuel, Marsters, Scot, Tsai, Siao Ping, Minoche, André, Seshagiri, Somasekar, Serrano, Sergi, Himmelbauer, Heinz, Bellmunt, Joaquim, Rovira, Ana, Settleman, Jeff, Bosch, Francesc, Albanell, Joan

“…By modeling acquired resistance to the EGFR antibody cetuximab in metastatic colorectal cancer, the authors identify a new mutation in the ectodomain of the…”
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Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer by Van Emburgh, Beth O., Arena, Sabrina, Siravegna, Giulia, Lazzari, Luca, Crisafulli, Giovanni, Corti, Giorgio, Mussolin, Benedetta, Baldi, Federica, Buscarino, Michela, Bartolini, Alice, Valtorta, Emanuele, Vidal, Joana, Bellosillo, Beatriz, Germano, Giovanni, Pietrantonio, Filippo, Ponzetti, Agostino, Albanell, Joan, Siena, Salvatore, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica, Montagut, Clara, Bardelli, Alberto

“…Blockade of the epidermal growth factor receptor (EGFR) with the monoclonal antibodies cetuximab or panitumumab is effective in a subset of colorectal cancers…”
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High mortality rate in COVID-19 patients with myeloproliferative neoplasms after abrupt withdrawal of ruxolitinib by Barbui, Tiziano, Vannucchi, Alessandro Maria, Alvarez-Larran, Alberto, Iurlo, Alessandra, Masciulli, Arianna, Carobbio, Alessandra, Ghirardi, Arianna, Ferrari, Alberto, Rossi, Giuseppe, Elli, Elena, Andrade-Campos, Marcio Miguel, Kabat, Mercedes Gasior, Kiladjian, Jean-Jaques, Palandri, Francesca, Benevolo, Giulia, Garcia-Gutierrez, Valentin, Fox, Maria Laura, Foncillas, Maria Angeles, Morcillo, Carmen Montoya, Rumi, Elisa, Osorio, Santiago, Papadopoulos, Petros, Bonifacio, Massimiliano, Cervantes, Keina Susana Quiroz, Serrano, Miguel Sagues, Carreno-Tarragona, Gonzalo, Sobas, Marta Anna, Lunghi, Francesca, Patriarca, Andrea, Elorza, Begona Navas, Angona, Anna, Mazo, Elena Magro, Koschmieder, Steffen, Ruggeri, Marco, Cuevas, Beatriz, Hernandez-Boluda, Juan Carlos, Abadia, Emma Lopez, Cirici, Blanca Xicoy, Guglielmelli, Paola, Garrote, Marta, Cattaneo, Daniele, Daffini, Rosa, Cavalca, Fabrizio, Bellosillo, Beatriz, Benajiba, Lina, Curto-Garcia, Natalia, Bellini, Marta, Betti, Silvia, De Stefano, Valerio, Harrison, Claire, Rambaldi, Alessandro

“…We report the clinical presentation and risk factors for survival in 175 patients with myeloproliferative neoplasms (MPN) and COVID-19, diagnosed between…”
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B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen by Puga, Irene, Cols, Montserrat, Barra, Carolina M, He, Bing, Cassis, Linda, Gentile, Maurizio, Comerma, Laura, Chorny, Alejo, Shan, Meimei, Xu, Weifeng, Magri, Giuliana, Knowles, Daniel M, Tam, Wayne, Chiu, April, Bussel, James B, Serrano, Sergi, Lorente, José Antonio, Bellosillo, Beatriz, Lloreta, Josep, Juanpere, Nuria, Alameda, Francesc, Baró, Teresa, de Heredia, Cristina Díaz, Torán, Núria, Català, Albert, Torrebadell, Montserrat, Fortuny, Claudia, Cusí, Victoria, Carreras, Carmen, Diaz, George A, Blander, J Magarian, Farber, Claire-Michèle, Silvestri, Guido, Cunningham-Rundles, Charlotte, Calvillo, Michaela, Dufour, Carlo, Notarangelo, Lucia Dora, Lougaris, Vassilios, Plebani, Alessandro, Casanova, Jean-Laurent, Ganal, Stephanie C, Diefenbach, Andreas, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Mahlaoui, Nizar, Donadieu, Jean, Chen, Kang, Cerutti, Andrea

“…Follicular T cells provide help to B cells to elicit antibody responses. Cerutti and colleagues show that neutrophils provide help to marginal-zone B cells…”
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Are Cutibacterium acnes present at the end of primary shoulder prosthetic surgeries responsible for infection? Prospective study by Torrens, Carlos, Bellosillo, Beatriz, Gibert, Joan, Alier, Albert, Santana, Fernando, Prim, Nuria, Corvec, Stéphane

“…The purpose of this study was to investigate if the C. acnes present at the end of a primary shoulder arthroplasty could be responsible for shoulder…”
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The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer by Sánchez-Martín, Francisco J, Bellosillo, Beatriz, Gelabert-Baldrich, Mariona, Dalmases, Alba, Cañadas, Israel, Vidal, Joana, Martinez, Alejandro, Argilés, Guillem, Siravegna, Giulia, Arena, Sabrina, Koefoed, Klaus, Visa, Laura, Arpí, Oriol, Horak, Ivan David, Iglesias, Mar, Stroh, Christopher, Kragh, Michael, Rovira, Ana, Albanell, Joan, Tabernero, Josep, Bardelli, Alberto, Montagut, Clara

“…Approved anti-EGFR antibodies cetuximab and panitumumab provide significant clinical benefit in patients with metastatic colorectal cancer (MCRC). However,…”
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Assessment and prognostic value of the European LeukemiaNet criteria for clinicohematologic response, resistance, and intolerance to hydroxyurea in polycythemia vera by Alvarez-Larrán, Alberto, Pereira, Arturo, Cervantes, Francisco, Arellano-Rodrigo, Eduardo, Hernández-Boluda, Juan-Carlos, Ferrer-Marín, Francisca, Angona, Anna, Gómez, Montse, Muiña, Begoña, Guillén, Helga, Teruel, Anabel, Bellosillo, Beatriz, Burgaleta, Carmen, Vicente, Vicente, Besses, Carles

“…Criteria of response and definition of resistance and intolerance to hydroxyurea (HU) in polycythemia vera (PV) were proposed by the European LeukemiaNet…”
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Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients by Siravegna, Giulia, Mussolin, Benedetta, Buscarino, Michela, Corti, Giorgio, Cassingena, Andrea, Crisafulli, Giovanni, Ponzetti, Agostino, Cremolini, Chiara, Amatu, Alessio, Lauricella, Calogero, Lamba, Simona, Hobor, Sebastijan, Avallone, Antonio, Valtorta, Emanuele, Rospo, Giuseppe, Medico, Enzo, Motta, Valentina, Antoniotti, Carlotta, Tatangelo, Fabiana, Bellosillo, Beatriz, Veronese, Silvio, Budillon, Alfredo, Montagut, Clara, Racca, Patrizia, Marsoni, Silvia, Falcone, Alfredo, Corcoran, Ryan B, Di Nicolantonio, Federica, Loupakis, Fotios, Siena, Salvatore, Sartore-Bianchi, Andrea, Bardelli, Alberto

“…Nat. Med.; doi:10.1038/nm.3870; corrected online 26 June 2015 In the version of this article initially published online, Alberto Bardelli's e-mail address was…”
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S3231 Multimodal Blood-Based Colorectal Cancer (CRC) Screening Test Performance in a Cohort of Individuals Presenting for Colonoscopy by Lowe, Elisha, Balboa, Joan Carles, Bellosillo, Beatriz, Axelrod, Haley D., Young-Greenwald, William W., Montagut, Clara, Bessa, Xavier

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Among classic myeloproliferative neoplasms, essential thrombocythemia is associated with the greatest risk of venous thromboembolism during COVID-19 by Barbui, Tiziano, De Stefano, Valerio, Alvarez-Larran, Alberto, Iurlo, Alessandra, Masciulli, Arianna, Carobbio, Alessandra, Ghirardi, Arianna, Ferrari, Alberto, Cancelli, Valeria, Elli, Elena Maria, Andrade-Campos, Marcio Miguel, Kabat, Mercedes Gasior, Kiladjian, Jean-Jaques, Palandri, Francesca, Benevolo, Giulia, Garcia-Gutierrez, Valentin, Fox, Maria Laura, Foncillas, Maria Angeles, Morcillo, Carmen Montoya, Rumi, Elisa, Osorio, Santiago, Papadopoulos, Petros, Bonifacio, Massimiliano, Cervantes, Keina Susana Quiroz, Serrano, Miguel Sagues, Carreno-Tarragona, Gonzalo, Sobas, Marta Anna, Lunghi, Francesca, Patriarca, Andrea, Elorza, Begoña Navas, Angona, Anna, Mazo, Elena Magro, Koschmieder, Steffen, Carli, Giuseppe, Cuevas, Beatriz, Hernandez-Boluda, Juan Carlos, Abadia, Emma Lopez, Cirici, Blanca Xicoy, Guglielmelli, Paola, Garrote, Marta, Cattaneo, Daniele, Daffini, Rosa, Cavalca, Fabrizio, Bellosillo, Beatriz, Benajiba, Lina, Curto-Garcia, Natalia, Bellini, Marta, Betti, Silvia, Harrison, Claire, Rambaldi, Alessandro, Vannucchi, Alessandro Maria

“…In a multicenter European retrospective study including 162 patients with COVID-19 occurring in essential thrombocythemia (ET, n  = 48), polycythemia vera (PV,…”
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Usefulness of p16INK4a staining for managing histological high-grade squamous intraepithelial cervical lesions by Miralpeix, Ester, Genovés, Jordi, Maria Solé-Sedeño, Josep, Mancebo, Gemma, Lloveras, Belen, Bellosillo, Beatriz, Alameda, Francesc, Carreras, Ramon

“…p16 INK4a (p16) tumor-suppressor protein is a biomarker of human papillomavirus (HPV) oncogenic activity that has revealed a high rate of positivity in…”
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Observation versus antiplatelet therapy as primary prophylaxis for thrombosis in low-risk essential thrombocythemia by Alvarez-Larrán, Alberto, Cervantes, Francisco, Pereira, Arturo, Arellano-Rodrigo, Eduardo, Pérez-Andreu, Virginia, Hernández-Boluda, Juan-Carlos, Ayats, Ramón, Salvador, Carlos, Muntañola, Ana, Bellosillo, Beatriz, Vicente, Vicente, Hernández-Nieto, Luis, Burgaleta, Carmen, Xicoy, Blanca, Besses, Carlos

“…The effectiveness of antiplatelet therapy as primary prophylaxis for thrombosis in low-risk essential thrombocythemia (ET) is not proven. In this study, the…”
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MultiCOVID: a multi modal deep learning approach for COVID-19 diagnosis by Hardy-Werbin, Max, Maiques, José Maria, Busto, Marcos, Cirera, Isabel, Aguirre, Alfons, Garcia-Gisbert, Nieves, Zuccarino, Flavio, Carbullanca, Santiago, Del Carpio, Luis Alexander, Ramal, Didac, Gayete, Ángel, Martínez-Roldan, Jordi, Marquez-Colome, Albert, Bellosillo, Beatriz, Gibert, Joan

“…The rapid spread of the severe acute respiratory syndrome coronavirus 2 led to a global overextension of healthcare. Both Chest X-rays (CXR) and blood test…”
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Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea by Alvarez-Larrán, Alberto, Díaz-González, Alvaro, Such, Esperanza, Mora, Elvira, Andrade-Campos, Marcio, García-Hernández, Carmen, Gómez-Casares, M. Teresa, García-Gutiérrez, Valentín, Carreño-Tarragona, Gonzalo, Garrote, Marta, Fernández-Ibarrondo, Lierni, Cervera, José, Bellosillo, Beatriz, Cervantes, Francisco, Hernández-Boluda, Juan Carlos

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Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia by Alvarez‐Larrán, Alberto, Senín, Alicia, Fernández‐Rodríguez, Concepción, Pereira, Arturo, Arellano‐Rodrigo, Eduardo, Gómez, Montse, Ferrer‐Marin, Francisca, Martínez‐López, Joaquín, Camacho, Laura, Colomer, Dolors, Angona, Anna, Navarro, Blanca, Cervantes, Francisco, Besses, Carlos, Bellosillo, Beatriz, Hernández‐Boluda, Juan Carlos

“…Summary The influence of driver mutations on leukaemic transformation was analysed in 1747 patients with polycythaemia vera or essential thrombocythaemia. With…”
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Characterization of genetic variants in the EGLN1/PHD2 gene identified in a European collection of patients with erythrocytosis by Delamare, Marine, Le Roy, Amandine, Pacault, Mathilde, Schmitt, Loïc, Garrec, Céline, Maaziz, Nada, Myllykoski, Matti, Rimbert, Antoine, Karaghiannis, Valéna, Aral, Bernard, Catherwood, Mark, Airaud, Fabrice, Mansour-Hendili, Lamisse, Hoogewijs, David, Peroni, Edoardo, Idriss, Salam, Lesieur, Valentine, Caillaud, Amandine, Si-Tayeb, Karim, Chariau, Caroline, Gaignerie, Anne, Rab, Minke, Haferlach, Torsten, Meggendorfer, Manja, Bézieau, Stéphane, Benetti, Andrea, Casadevall, Nicole, Hirsch, Pierre, Rose, Christian, Wemeau, Mathieu, Galacteros, Frédéric, Cassinat, Bruno, Bellosillo, Beatriz, Bento, Celeste, Van Wijk, Richard, Petrides, Petro E, Randi, Maria Luigia, McMullin, Mary Frances, Koivunen, Peppi, Girodon, François, Gardie, Betty

“…Hereditary erythrocytosis (HE) is a rare hematological disorder characterized by an excess of red blood cell production. Here we describe a European…”
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