Search Results - "BELL, W"

Clinical actionability of molecular targets in endometrial cancer by Urick, Mary Ellen, Bell, Daphne W.

“…Endometrial cancer accounts for ~76,000 deaths among women each year worldwide. Disease mortality and the increasing number of new diagnoses make endometrial…”
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Molecular Genetics of Endometrial Carcinoma by Bell, Daphne W, Ellenson, Lora Hedrick

“…Endometrial cancer is the most commonly diagnosed gynecologic malignancy in the United States. Endometrioid endometrial carcinomas constitute approximately 85%…”
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DockRMSD: an open-source tool for atom mapping and RMSD calculation of symmetric molecules through graph isomorphism by Bell, Eric W., Zhang, Yang

“…Comparison of ligand poses generated by protein–ligand docking programs has often been carried out with the assumption of direct atomic correspondence between…”
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Extreme Conditions in the Bering Sea (2017–2018): Record‐Breaking Low Sea‐Ice Extent by Stabeno, Phyllis J., Bell, Shaun W.

“…The lowest winter‐maximum areal sea‐ice coverage on record (1980–2019) in the Bering Sea occurred in the winter of 2017/2018. Sea ice arrived late due to warm…”
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Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV‑1 by Zhang, Chengxin, Zheng, Wei, Huang, Xiaoqiang, Bell, Eric W, Zhou, Xiaogen, Zhang, Yang

“…As the infection of 2019-nCoV coronavirus is quickly developing into a global pneumonia epidemic, the careful analysis of its transmission and cellular…”
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Predicting effective microRNA target sites in mammalian mRNAs by Agarwal, Vikram, Bell, George W, Nam, Jin-Wu, Bartel, David P

“…MicroRNA targets are often recognized through pairing between the miRNA seed region and complementary sites within target mRNAs, but not all of these canonical…”
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HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers by Mendillo, Marc L., Santagata, Sandro, Koeva, Martina, Bell, George W., Hu, Rong, Tamimi, Rulla M., Fraenkel, Ernest, Ince, Tan A., Whitesell, Luke, Lindquist, Susan

“…Heat-Shock Factor 1 (HSF1), master regulator of the heat-shock response, facilitates malignant transformation, cancer cell survival, and proliferation in model…”
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Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks by Li, Yang, Zhang, Chengxin, Bell, Eric W, Zheng, Wei, Zhou, Xiaogen, Yu, Dong-Jun, Zhang, Yang

“…The topology of protein folds can be specified by the inter-residue contact-maps and accurate contact-map prediction can help ab initio structure folding. We…”
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Folding non-homologous proteins by coupling deep-learning contact maps with I-TASSER assembly simulations by Zheng, Wei, Zhang, Chengxin, Li, Yang, Pearce, Robin, Bell, Eric W., Zhang, Yang

“…Structure prediction for proteins lacking homologous templates in the Protein Data Bank (PDB) remains a significant unsolved problem. We developed a protocol,…”
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Specific Protein Detection Using Designed DNA Carriers and Nanopores by Bell, Nicholas A. W, Keyser, Ulrich F

“…Nanopores are a versatile technique for the detection and characterization of single molecules in solution. An ongoing challenge in the field is to find…”
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Histamine Limits by Country: A Survey and Review by DeBEER, John, Bell, Jon W, Nolte, Fred, Arcieri, Julian, Correa, Gerson

“…Histamine is a biogenic amine and a food safety hazard, and it is the only biogenic amine regulated by statute or hazard analysis and critical control point…”
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Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs by Baek, Daehyun, Bartel, David P, Garcia, David M, Shin, Chanseok, Bell, George W, Grimson, Andrew

“…A single miRNA can target hundreds of distinct transcripts, but some miRNAs such as C. elegans lsy-6 have very low target proficiency. The reasons behind this…”
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Protein structure prediction using deep learning distance and hydrogen‐bonding restraints in CASP14 by Zheng, Wei, Li, Yang, Zhang, Chengxin, Zhou, Xiaogen, Pearce, Robin, Bell, Eric W., Huang, Xiaoqiang, Zhang, Yang

“…In this article, we report 3D structure prediction results by two of our best server groups (“Zhang‐Server” and “QUARK”) in CASP14. These two servers were…”
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Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging by Mihaylova, Maria M., Cheng, Chia-Wei, Cao, Amanda Q., Tripathi, Surya, Mana, Miyeko D., Bauer-Rowe, Khristian E., Abu-Remaileh, Monther, Clavain, Laura, Erdemir, Aysegul, Lewis, Caroline A., Freinkman, Elizaveta, Dickey, Audrey S., La Spada, Albert R., Huang, Yanmei, Bell, George W., Deshpande, Vikram, Carmeliet, Peter, Katajisto, Pekka, Sabatini, David M., Yilmaz, Ömer H.

“…Diet has a profound effect on tissue regeneration in diverse organisms, and low caloric states such as intermittent fasting have beneficial effects on…”
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The emerging genomic landscape of endometrial cancer by Le Gallo, Matthieu, Bell, Daphne W

“…Endometrial cancer is responsible for approximately 74 000 deaths annually among women worldwide. It is a heterogeneous disease comprising multiple histologic…”
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Accounting for correlated error in the assimilation of high‐resolution sounder data by Weston, P. P., Bell, W., Eyre, J. R.

“…Until January 2013, data from the high‐resolution sounder IASI were assimilated with a diagonal observation‐error covariance matrix within the Met Office…”
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Quantifying Nanomolar Protein Concentrations Using Designed DNA Carriers and Solid-State Nanopores by Kong, Jinglin, Bell, Nicholas A. W, Keyser, Ulrich F

“…Designed “DNA carriers” have been proposed as a new method for nanopore based specific protein detection. In this system, target protein molecules bind to a…”
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Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors by Soldner, Frank, Hockemeyer, Dirk, Beard, Caroline, Gao, Qing, Bell, George W., Cook, Elizabeth G., Hargus, Gunnar, Blak, Alexandra, Cooper, Oliver, Mitalipova, Maisam, Isacson, Ole, Jaenisch, Rudolf

“…Induced pluripotent stem cells (iPSCs) derived from somatic cells of patients represent a powerful tool for biomedical research and may provide a source for…”
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Epidermal growth factor receptor mutations in lung cancer by Haber, Daniel A, Sharma, Sreenath V, Bell, Daphne W, Settleman, Jeffrey

“…The development and clinical application of inhibitors that target the epidermal growth factor receptor (EGFR) provide important insights for new lung cancer…”
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Assimilation of satellite data in numerical weather prediction. Part II: Recent years by Eyre, J. R., Bell, W., Cotton, J., English, S. J., Forsythe, M., Healy, S. B., Pavelin, E. G.

“…Developments in the assimilation of satellite data in numerical weather prediction (NWP), from the first experiments in the late 1960s to the present day, are…”
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