Search Results - "BELL, D. R."

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease by Deane, R, Bell, R D, Sagare, A, Zlokovic, B V

“…The main receptors for amyloid-beta peptide (Abeta) transport across the blood-brain barrier (BBB) from brain to blood and blood to brain are low-density…”
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Transient geotherms in Archean continental lithosphere: New constraints on thickness and heat production of the subcontinental lithospheric mantle by Michaut, C., Jaupart, C., Bell, D. R.

“…Because of its large thickness and thermal relaxation time, Archean lithosphere cannot be in thermal equilibrium with the instantaneous rate of heat production…”
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Lateral variation in upper mantle viscosity: role of water by Dixon, Jacqueline E, Dixon, T.H, Bell, D.R, Malservisi, R

“…Differences in the viscosity of the earth's upper mantle beneath the western US (~10 super 18-10 super 19 Pa s) and global average values based on glacial…”
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Abundance and Partitioning of OH in a High-pressure Magmatic System: Megacrysts from the Monastery Kimberlite, South Africa by BELL, DAVID R., ROSSMAN, GEORGE R., MOORE, RORY O.

“…Concentrations of OH, and major and trace elements were determined in a suite of mantle-derived megacrysts that represent the crystallization products of a…”
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Hf Isotope Systematics of Kimberlites and their Megacrysts: New Constraints on their Source Regions by NOWELL, G. M., PEARSON, D. G., BELL, D. R., CARLSON, R. W., SMITH, C. B., KEMPTON, P. D., NOBLE, S. R.

“…Kimberlites from Southern Africa, along with their low-Cr megacrysts, have unusual Hf–Nd isotopic characteristics. Group I and Transitional kimberlites define…”
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Garnet Lherzolites from the Kaapvaal Craton (South Africa): Trace Element Evidence for a Metasomatic History by GRÉGOIRE, M., BELL, D. R., LE ROEX, A. P.

“…Kimberlites from the Kaapvaal craton have sampled numerous mantle garnet lherzolites in addition to garnet harzburgites. Trace element characteristics of…”
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Chronic Strongyloides stercoralis infection in former British Far East prisoners of war by Gill, G.V., Welch, E., Bailey, J.W., Bell, D.R., Beeching, N.J.

“…Background: Chronic infections with the nematode worm Strongyloides stercoralis can occur in former WWII Far East prisoners of war (FEPOWs). The condition may…”
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Age, Composition and Thermal Characteristics of South African Off-Craton Mantle Lithosphere: Evidence for a Multi-Stage History by Janney, P. E., Shirey, S. B., Carlson, R. W., Pearson, D. G., Bell, D. R., Le Roex, A. P., Ishikawa, A., Nixon, P. H., Boyd, F. R.

“…A mineral chemistry and whole-rock major element, platinum group element (PGE), and Re–Os isotope dataset is presented for a large suite of mantle xenoliths…”
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Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein. The role of hsp90 by Bell, D R, Poland, A

“…The aryl hydrocarbon receptor (AhR) has been shown to interact with an immunophilin-like molecule known as AhR-interacting protein (AIP) and to enhance AhR…”
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Trace element geochemistry of phlogopite-rich mafic mantle xenoliths: their classification and their relationship to phlogopite-bearing peridotites and kimberlites revisited by Grégoire, M., Bell, D., Le Roex, A.

“…Kimberlite magmas from the Kimberley area of South Africa have sampled two main types of phlogopite-rich mafic xenoliths which represent deep mantle…”
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Silica and volatile-element metasomatism of Archean mantle: a xenolith-scale example from the Kaapvaal Craton by Bell, D. R., Grégoire, M., Grove, T. L., Chatterjee, N., Carlson, R. W., Buseck, P. R.

“…Textural evidence in a composite garnet harzburgite mantle xenolith from Kimberley, South Africa, suggests metasomatism of a severely melt-depleted substrate…”
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‘Front and Back’ Flaps for Multiple Dorsal and Palmar Digital Skin Loss by Senarath-Yapa, K., Bell, D.R.

“…We describe a technique modification of the ‘many tailed’ flaps for multiple digital defects in adjacent digits described in 1980. This is a versatile…”
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Potential role for peroxisome proliferator activated receptor (PPAR) in preventing colon cancer by Jackson, L, Wahli, W, Michalik, L, Watson, S A, Morris, T, Anderton, K, Bell, D R, Smith, J A, Hawkey, C J, Bennett, A J

“…Background: Peroxisome proliferator activated receptors (PPARs) are nuclear hormone receptors involved in genetic control of many cellular processes. PPAR and…”
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Epoetin alpha prevents anaemia and reduces transfusion requirements in patients undergoing primarily platinum-based chemotherapy for small cell lung cancer by THATCHER, N, DE CAMPOS, E. S, SCHATZMANN, E, STOCKER, H, BELL, D. R, STEWARD, W. P, VARGHESE, G, MORANT, R, VANSTEENKISTE, J. F, ROSSO, R, EWERS, S. B, SUNDAL, E

“…Anaemia commonly occurs in cancer patients receiving chemotherapy, often necessitating blood transfusion. This multicentre study was designed to evaluate the…”
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Rheumatoid Arthritis-Associated Necrotizing Scleritis and Peripheral Ulcerative Keratitis Treated Successfully With Infliximab by Atchia, Ismael I, Kidd, C Elizabeth, Bell, R W. D

“…In patients with rheumatoid arthritis (RA), necrotizing scleritis, an ocular manifestation of a systemic vasculitic process, is associated with significant…”
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Apolipoprotein E controls cerebrovascular integrity via cyclophilin A by Bell, Robert D., Winkler, Ethan A., Singh, Itender, Sagare, Abhay P., Deane, Rashid, Wu, Zhenhua, Holtzman, David M., Betsholtz, Christer, Armulik, Annika, Sallstrom, Jan, Berk, Bradford C., Zlokovic, Berislav V.

“…The APOE4-mediated proinflammatory pathway is shown to initiate blood–brain barrier breakdown and resulting neurodegeneration in transgenic mice. Restoring the…”
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Fatal pulmonary toxicity resulting from treatment with gemcitabine by Pavlakis, Nick, Bell, David R., Millward, Michael J., Levi, John A.

“…BACKGROUND Pulmonary toxicity reported with gemcitabine is usually mild and self‐limiting. The authors report a series of three patients who had…”
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Leprosy in Britain: 50 years experience in Liverpool by Gill, A.L., Bell, D.R., Gill, G.V., Wyatt, G.B., Beeching, N.J.

“…Background: Leprosy is a chronic infection that presents with varying dermal and neurological symptoms, and which can lead to extensive disability and…”
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Incorporation of hydroxyl in upper-mantle clinopyroxenes by Smyth, J. R, Bell, D. R, Rossman, G. R

“…Water and hydroxyl play an important part in determining the properties of minerals and melts in the Earth's upper mantle. Some of this hydroxyl is shown to be…”
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Estrogen pretreatment directly potentiates endothelium-dependent vasorelaxation of porcine coronary arteries by Bell, D R, Rensberger, H J, Koritnik, D R, Koshy, A

“…We tested whether vasorelaxation of coronary arteries is altered after overnight (18-22 h) exposure to physiological levels of 17 beta-estradiol. Ring segments…”
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