Search Results - "BEKERS, Otto"

Is a Vitamin K Epoxide Reductase Complex Subunit 1 ( VKORC1 ) Polymorphism a Risk Factor for Nephrolithiasis in Sarcoidosis? by Drent, Marjolein, Wijnen, Petal, Bekers, Otto, Bast, Aalt

“…Sarcoidosis is a systemic inflammatory disorder characterized by granuloma formation in various organs. It has been associated with nephrolithiasis. The…”
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A comparison of machine learning models versus clinical evaluation for mortality prediction in patients with sepsis by van Doorn, William P T M, Stassen, Patricia M, Borggreve, Hella F, Schalkwijk, Maaike J, Stoffers, Judith, Bekers, Otto, Meex, Steven J R

“…Patients with sepsis who present to an emergency department (ED) have highly variable underlying disease severity, and can be categorized from low to high…”
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Trends in mass spectrometry imaging for cardiovascular diseases by Mezger, Stephanie T. P., Mingels, Alma M. A., Bekers, Otto, Cillero-Pastor, Berta, Heeren, Ron M. A.

“…Mass spectrometry imaging (MSI) is a widely established technology; however, in the cardiovascular research field, its use is still emerging. The technique has…”
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Acute Hemodynamic Response and Uremic Toxin Removal in Conventional and Extended Hemodialysis and Hemodiafiltration: A Randomized Crossover Study by Cornelis, Tom, MD, van der Sande, Frank M., MD, PhD, Eloot, Sunny, MD, PhD, Cardinaels, Eline, MSc, Bekers, Otto, MD, PhD, Damoiseaux, Jan, MD, PhD, Leunissen, Karel M., MD, PhD, Kooman, Jeroen P., MD, PhD

“…Background Intensive hemodialysis (HD) may have significant benefits. Recently, the role of extended hemodiafiltration (HDF) has gained interest. The aim of…”
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VKORC1 and CYP2C9 Polymorphisms: A Case Report in a Dutch Family with Pulmonary Fibrosis by Wijnen, Petal, Drent, Marjolein, Bekers, Otto, Verschakelen, Johny, Bast, Aalt

“…Here, we describe a Dutch family with idiopathic pulmonary fibrosis (IPF). We hypothesized that there might be an association between the presence of Vitamin K…”
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Protein Alterations in Cardiac Ischemia/Reperfusion Revealed by Spatial-Omics by Mezger, Stephanie T P, Mingels, Alma M A, Soulié, Matthieu, Peutz-Kootstra, Carine J, Bekers, Otto, Mulder, Paul, Heeren, Ron M A, Cillero-Pastor, Berta

“…Myocardial infarction is the most common cause of death worldwide. An understanding of the alterations in protein pathways is needed in order to develop…”
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Ammonium accumulation in commercially available embryo culture media and protein supplements during storage at 2–8°C and during incubation at 37°C by Kleijkers, Sander H.M., van Montfoort, Aafke P.A., Bekers, Otto, Coonen, Edith, Derhaag, Josien G., Evers, Johannes L.H., Dumoulin, John C.M.

“…Abstract STUDY QUESTION Does ammonium accumulate in commercially available culture media and protein supplements used for in vitro development of human…”
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Biological Variation of Creatinine, Cystatin C, and eGFR over 24 Hours by Hilderink, Judith M, van der Linden, Noreen, Kimenai, Dorien M, Litjens, Elisabeth J R, Klinkenberg, Lieke J J, Aref, Breshna M, Aziz, Fahra, Kooman, Jeroen P, Rennenberg, Roger J M W, Bekers, Otto, Koopmans, Richard P, Meex, Steven J R

“…Estimated glomerular filtration rate (eGFR) is widely used in clinical practice. This study assessed the within-subject biological variation (CV ) of different…”
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Tamsulosin Associated with Interstitial Lung Damage in CYP2D6 Variant Alleles Carriers by Jessurun, Naomi T, Wijnen, Petal A, Bast, Aalt, van Puijenbroek, Eugène P, Bekers, Otto, Drent, Marjolein

“…Drugs are serious but underestimated causative agents of interstitial lung disease (ILD). Both cytotoxic and immune mechanisms may be involved in drug-induced…”
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Metformin and high-sensitivity cardiac troponin I and T trajectories in type 2 diabetes patients: a post-hoc analysis of a randomized controlled trial by Stultiens, Johanna M G, Top, Wiebe M C, Kimenai, Dorien M, Lehert, Philippe, Bekers, Otto, Stehouwer, Coen D A, Kooy, Adriaan, Meex, Steven J R

“…Metformin has favorable effects on cardiovascular outcomes in both newly onset and advanced type 2 diabetes, as previously reported findings from the UK…”
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Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis by de Brouwer, Bart, Drent, Marjolein, van den Ouweland, Jody M W, Wijnen, Petal A, van Moorsel, Coline H M, Bekers, Otto, Grutters, Jan C, White, Eric S, Janssen, Rob

“…Although chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) seem to be opposite entities from a clinical perspective, common…”
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High-Sensitivity Cardiac Troponin Concentrations in Patients with Chest Discomfort: Is It the Heart or the Kidneys As Well? by Cardinaels, Eline P M, Altintas, Sibel, Versteylen, Mathijs O, Joosen, Ivo A, Jellema, Laurens-Jan C, Wildberger, Joachim E, Das, Marco, Crijns, Harry J, Bekers, Otto, van Dieijen-Visser, Marja P, Kietselaer, Bastiaan L, Mingels, Alma M A

“…High-sensitivity cardiac troponins (hs-cTn) are the preferred biomarkers to detect myocardial injury, making them promising risk-stratifying tools for patients…”
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Multi-Site Coronary Vein Sampling Study on Cardiac Troponin T Degradation in Non-ST-Segment-Elevation Myocardial Infarction: Toward a More Specific Cardiac Troponin T Assay by Damen, Sander A J, Vroemen, Wim H M, Brouwer, Marc A, Mezger, Stephanie T P, Suryapranata, Harry, van Royen, Niels, Bekers, Otto, Meex, Steven J R, Wodzig, Will K W H, Verheugt, Freek W A, de Boer, Douwe, Cramer, G Etienne, Mingels, Alma M A

“…Background Cardiac troponin T ( cTnT ) is seen in many other conditions besides myocardial infarction, and recent studies demonstrated distinct forms of cTnT …”
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Cardiac troponin concentrations following exercise and the association with cardiovascular disease and outcomes: rationale and design of the prospective TREAT cohort study by Janssen, Sylvan L J E, Lamers, Sacha K, Vroemen, Wim H M, Denessen, Ellen J S, Berge, Kristian, Bekers, Otto, Hopman, Maria T E, Brink, Monique, Habets, Jesse, Nijveldt, Robin, Van Everdingen, Wouter M, Aengevaeren, Vincent L, Mingels, Alma M A, Eijsvogels, Thijs M H

“…Exercise can produce transient elevations of cardiac troponin (cTn) concentrations, which may resemble the cTn release profile of myocardial infarction…”
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Longitudinal changes in placental biomarkers in women with early versus late placental dysfunction by Hendrix, Manouk L. E., Palm, Kirsten C. M., Van Kuijk, Sander M. J., Bekers, Otto, Spaanderman, Marc E. A., Bons, Judith A. P., Al-Nasiry, Salwan

“…Objective: To evaluate longitudinal changes of angiogenic biomarkers in early- (EO-PD) versus late-onset (LO-PD) placental dysfunction. Methods: Serum PlGF and…”
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Do Apolipoprotein E Genotype and Educational Attainment Predict the Rate of Cognitive Decline in Normal Aging? A 12-Year Follow-Up of the Maastricht Aging Study by Van Gerven, Pascal W. M., Van Boxtel, Martin P. J., Ausems, Eleonora E. B., Bekers, Otto, Jolles, Jelle

“…Objective: We investigated suspected longitudinal interaction effects of apolipoprotein E (APOE) genotype and educational attainment on cognitive decline in…”
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Butyrophilin-like 2 in pulmonary sarcoidosis: a factor for susceptibility and progression? by Wijnen, Petal A, Voorter, Christina E, Nelemans, Patty J, Verschakelen, Johny A, Bekers, Otto, Drent, Marjolein

“…Abstract The aims of this study were to assess the association of BTNL2 G16071 A with the course of pulmonary sarcoidosis and to verify the association with…”
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Clinical Interpretation of Elevated Concentrations of Cardiac Troponin T, but Not Troponin I, in Nursing Home Residents by Cardinaels, Eline P.M., PhD, Daamen, Mariëlle A.M.J., MD, Bekers, Otto, PhD, ten Kate, Joop, PhD, Niens, Marijke, PhD, van Suijlen, Jeroen D.E., PhD, van Dieijen-Visser, Marja P., PhD, Brunner-La Rocca, Hans-Peter, MD, PhD, Schols, Jos M.G.A., MD, PhD, Mingels, Alma M.A., PhD

“…Abstract Objective Cardiac troponins T (cTnT) and I (cTnI) are the preferred biomarkers to detect myocardial damage. The present study explores the value of…”
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Oral bioavailability of ATP after prolonged administration by Coolen, Erik J. C. M., Arts, Ilja C. W., Bekers, Otto, Vervaet, Chris, Bast, Aalt, Dagnelie, Pieter C.

“…Purinergic receptors are important for the regulation of inflammation, muscle contraction, neurotransmission and nociception. Extracellular ATP and its…”
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Relationship between drug-induced interstitial lung diseases and cytochrome P450 polymorphisms by Wijnen, Petal AHM, Bekers, Otto, Drent, Marjolein

“…PURPOSE OF REVIEWInterstitial lung disease and especially drug-induced interstitial lung disease can occur as a cause of drug(s) or drug–drug interactions. In…”
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