Search Results - "BEINERT, H"

Iron-sulfur proteins: ancient structures, still full of surprises by Beinert, H

“…This article is a survey of the properties and functions of Fe-S proteins under the following headings: sulfur and iron; iron-sulfur clusters; evolution of…”
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The Reaction of Fluorocitrate with Aconitase and the Crystal Structure of the Enzyme-Inhibitor Complex by Lauble, H., Kennedy, M. C., Emptage, M. H., Beinert, H., Stout, C. D.

“…It has been known for many years that fluoroacetate and fluorocitrate when metabolized are highly toxic, and that at least one effect of fluorocitrate is to…”
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Association of a Polynuclear Iron-Sulfur Center with a Mutant FNR Protein Enhances DNA Binding by Khoroshilova, Natalia, Beinert, Helmut, Kiley, Patricia J.

“…In the facultative anaerobe Escherichia coli, the transcription factor FNR (fumarate nitrate reduction) regulates gene expression in response to oxygen…”
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Purification and Characterization of Cytosolic Aconitase from Beef Liver and its Relationship to the Iron-Responsive Element Binding Protein by Kennedy, Mary Claire, Mende-Mueller, Liane, Blondin, George A., Beinert, Helmut

“…In recent reports attention has been drawn to the extensive amino acid homology between pig heart, yeast, and Escherichia coli aconitases (EC 4.2.1.3) and the…”
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Cellular Regulation of the Iron-Responsive Element Binding Protein: Disassembly of the Cubane Iron-Sulfur Cluster Results in High-Affinity RNA Binding by Haile, David J., Rouault, Tracey A., Harford, Joe B., Kennedy, Mary Claire, Blondin, George A., Beinert, Helmut, Klausner, Richard D.

“…The translation of ferritin mRNA and degradation of transferrin receptor mRNA are regulated by the interaction of an RNA-binding protein, the iron-responsive…”
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Crystal structures of aconitase with isocitrate and nitroisocitrate bound by Lauble, H, Kennedy, M. C, Beinert, H, Stout, C. D

“…The crystal structures of mitochondrial aconitase with isocitrate and nitroisocitrate bound have been solved and refined to R factors of 0.179 and 0.161,…”
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The role of iron in the activation-inactivation of aconitase by Kennedy, M C, Emptage, M H, Dreyer, J L, Beinert, H

“…Methods are described for the convenient preparation of aconitase from beef heart mitochondria in its inactive [3Fe-4S] form and largely in its active [4Fe-4S]…”
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Looking at enzymes in action in the 1950s by Beinert, Helmut

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The role of Fe–S proteins in sensing and regulation in bacteria by Kiley, Patricia J, Beinert, Helmut

“…Fe–S clusters are key to the sensing and transcription functions of three transcription factors, FNR, IscR and SoxR. All three proteins were discovered in…”
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The state of cluster SH and S2- of aconitase during cluster interconversions and removal. A convenient preparation of apoenzyme by Kennedy, M C, Beinert, H

“…During the interconversion of the various cluster types observed in aconitase ([4Fe-4S]1+,2+, [3Fe-4S]0,1+, cubane, or linear types) and production of…”
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Copper in biological systems. A report from the 7th Manziana conference, held at Santa Severa, September 11–15, 1995 by Beinert, Helmut

“…In this fifty-seven page report, the author attempts to give the essence of the twenty-four lectures and of an about equal number of posters, including…”
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Evidence for the formation of a linear [3Fe-4S] cluster in partially unfolded aconitase by Kennedy, M C, Kent, T A, Emptage, M, Merkle, H, Beinert, H, Münck, E

“…Beef heart aconitase, as isolated under aerobic conditions, is inactive and contains a [3Fe-4S]1+ cluster. On incubation at pH greater than 9.5 (or treatment…”
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Iron-sulphur clusters: agents of electron transfer and storage, and direct participants in enzymic reactions. Tenth Keilin memorial lecture by Beinert, H

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Mutational analysis of active site residues in pig heart aconitase by ZHENG, L, KENNEDY, M. C, BEINERT, H, ZALKIN, H

“…A cDNA encoding mature porcine heart aconitase was over-expressed in Escherichia coli under the control of a phage T7 promoter. Recombinant aconitase purified…”
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Overexpression of iron-responsive element-binding protein and its analytical characterization as the RNA-binding form, devoid of an iron-sulfur cluster by Basilion, J P, Kennedy, M C, Beinert, H, Massinople, C M, Klausner, R D, Rouault, T A

“…The iron-responsive element-binding protein (IRE-BP) has been defined and identified as an RNA-binding protein found in iron-deprived eukaryotic cells. IRE-BP…”
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Iron-Sulfur Clusters: Nature's Modular, Multipurpose Structures by Beinert, Helmut, Holm, Richard H., Munck, Eckard

“…Iron-sulfur proteins are found in all life forms. Most frequently, they contain Fe$_2$S$_2$, Fe$_3$S$_4$, and Fe$_4$S$_4$ clusters. These modular clusters…”
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Mössbauer Study of the Inactive Fe3S4 and Fe3Se4 and the Active Fe4Se4 Forms of Beef Heart Aconitase by Surerus, Kristene K., Kennedy, Mary Claire, Beinert, Helmut, Münck, Eckard

“…Active beef heart aconitase contains an ironsulfur cluster with an [Fe4S4]2+ core. This cluster can be converted into Fe3S4 with concomitant loss of enzymatic…”
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A new iron-sulfur flavoprotein of the respiratory chain. A component of the fatty acid beta oxidation pathway by Ruzicka, F J, Beinert, H

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Fatty acid oxidation in soluble systems of mammalian origin: the beginnings by Beinert, H

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IscR, An Fe-S Cluster-Containing Transcription Factor, Represses Expression of Escherichia coli Genes Encoding Fe-S Cluster Assembly Proteins by Schwartz, Christopher J., Giel, Jennifer L., Patschkowski, Thomas, Luther, Christopher, Ruzicka, Frank J., Beinert, Helmut, Kiley, Patricia J.

“…IscR (iron-sulfur cluster regulator) is encoded by an ORF located immediately upstream of genes coding for the Escherichia coli Fe-S cluster assembly proteins,…”
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