Search Results - "BEHRENS, Michaela"
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Identification of domains in Plasmodium falciparum proteins of unknown function using DALI search on AlphaFold predictions
Published in Scientific reports (08-05-2024)“…Plasmodium falciparum , the causative agent of malaria, poses a significant global health challenge, yet much of its biology remains elusive. A third of the…”
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Journal Article -
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The Kelch13 compartment contains highly divergent vesicle trafficking proteins in malaria parasites
Published in PLoS pathogens (01-12-2023)“…Single amino acid changes in the parasite protein Kelch13 (K13) result in reduced susceptibility of P. falciparum parasites to artemisinin and its derivatives…”
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Journal Article -
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The infected hematometra in a rudimentary noncommunicating horn misdiagnosed as pelvic mass: A case report
Published in International journal of surgery case reports (01-01-2020)“…•The rudimentary noncommunicating horn with a functional endometrial cavity is should be treated promptly to prevent obstetric and gynecologic…”
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Journal Article -
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The newly discovered role of endocytosis in artemisinin resistance
Published in Medicinal research reviews (01-11-2021)“…Artemisinin and its derivatives (ART) are the cornerstone of malaria treatment as part of artemisinin combination therapy (ACT). However, reduced…”
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Journal Article -
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Accelerated elimination of ultraviolet-induced DNA damage through apoptosis in CDC25A-deficient skin
Published in Carcinogenesis (New York) (01-09-2012)“…Cell division cycle 25A (CDC25A) is a dual-specificity phosphatase that removes inhibitory phosphates from cyclin-dependent kinases, allowing cell-cycle…”
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Journal Article -
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A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime – MVA85A boost in healthy UK adults
Published in Vaccine (22-01-2020)“…This phase I trial evaluated the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime-MVA85A boost, previously…”
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Journal Article -
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Role of Rabenosyn-5 and Rab5b in host cell cytosol uptake reveals conservation of endosomal transport in malaria parasites
Published in PLoS biology (31-05-2024)“…Vesicular trafficking, including secretion and endocytosis, plays fundamental roles in the unique biology of Plasmodium falciparum blood-stage parasites…”
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Journal Article -
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Gene-by-gene screen of the unknown proteins encoded on Plasmodium falciparum chromosome 3
Published in Cell systems (18-01-2023)“…Taxon-specific proteins are key determinants defining the biology of all organisms and represent prime drug targets in pathogens. However, lacking…”
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Journal Article -
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How the Protein Antibiotic Pyocin S5 Kills Pseudomonas Aeruginosa
Published 01-01-2019“…Antimicrobial resistance is a deadly threat that is on the rise globally. Failure of small molecule antibiotic drug discovery programs and an increasing…”
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Dissertation -
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The infected hematometra in a rudimentary noncommunicating horn misdiagnosed as pelvic mass: A case report
Published in International journal of surgery case reports (01-01-2020)“…INTRODUCTIONThe rudimentary noncommunicating horn with a functional endometrial cavity is rare and often challenging to diagnose because of the variety in…”
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