Search Results - "BEHRENS, Georg"

The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic by Hoffmann, Markus, Krüger, Nadine, Schulz, Sebastian, Cossmann, Anne, Rocha, Cheila, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Moldenhauer, Anna-Sophie, Winkler, Martin S., Lier, Martin, Dopfer-Jablonka, Alexandra, Jäck, Hans-Martin, Behrens, Georg M.N., Pöhlmann, Stefan

“…The rapid spread of the SARS-CoV-2 Omicron variant suggests that the virus might become globally dominant. Further, the high number of mutations in the viral…”
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COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses by Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Dragon, Anna C., Gussarow, Daniel, Vogel, Alexander, Krettek, Ulrike, Gödecke, Nina, Yilmaz, Mustafa, Kraft, Anke R.M., Hoeper, Marius M., Pink, Isabell, Schmidt, Julius J., Li, Yang, Welte, Tobias, Maecker-Kolhoff, Britta, Martens, Jörg, Berger, Marc Moritz, Lobenwein, Corinna, Stankov, Metodi V., Cornberg, Markus, David, Sascha, Behrens, Georg M.N., Witzke, Oliver, Blasczyk, Rainer, Eiz-Vesper, Britta

“…Cellular and humoral immunity to SARS-CoV-2 is critical to control primary infection and correlates with severity of disease. The role of SARS-CoV-2-specific…”
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SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination by Hoffmann, Markus, Hofmann-Winkler, Heike, Krüger, Nadine, Kempf, Amy, Nehlmeier, Inga, Graichen, Luise, Arora, Prerna, Sidarovich, Anzhalika, Moldenhauer, Anna-Sophie, Winkler, Martin S., Schulz, Sebastian, Jäck, Hans-Martin, Stankov, Metodi V., Behrens, Georg M.N., Pöhlmann, Stefan

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants threatens efforts to contain the coronavirus disease 2019 (COVID-19)…”
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Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals by Behrens, Georg M. N., Cossmann, Anne, Stankov, Metodi V., Witte, Torsten, Ernst, Diana, Happle, Christine, Jablonka, Alexandra

“…There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows…”
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Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination by Barros-Martins, Joana, Hammerschmidt, Swantje I., Cossmann, Anne, Odak, Ivan, Stankov, Metodi V., Morillas Ramos, Gema, Dopfer-Jablonka, Alexandra, Heidemann, Annika, Ritter, Christiane, Friedrichsen, Michaela, Schultze-Florey, Christian, Ravens, Inga, Willenzon, Stefanie, Bubke, Anja, Ristenpart, Jasmin, Janssen, Anika, Ssebyatika, George, Bernhardt, Günter, Münch, Jan, Hoffmann, Markus, Pöhlmann, Stefan, Krey, Thomas, Bošnjak, Berislav, Förster, Reinhold, Behrens, Georg M. N.

“…Currently approved viral vector-based and mRNA-based vaccine approaches against coronavirus disease 2019 (COVID-19) consider only homologous prime-boost…”
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Comparable neutralisation evasion of SARS-CoV-2 omicron subvariants BA.1, BA.2, and BA.3 by Arora, Prerna, Zhang, Lu, Rocha, Cheila, Sidarovich, Anzhalika, Kempf, Amy, Schulz, Sebastian, Cossmann, Anne, Manger, Bernhard, Baier, Eva, Tampe, Björn, Moerer, Onnen, Dickel, Steffen, Dopfer-Jablonka, Alexandra, Jäck, Hans-Martin, Behrens, Georg M N, Winkler, Martin S, Pöhlmann, Stefan, Hoffmann, Markus

“…The viral spike (S) protein is the key target of the neutralising antibody response, and the omicron variant harbours more than 35 mutations in the S protein,…”
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Effect of hybrid immunity and bivalent booster vaccination on omicron sublineage neutralisation by Hoffmann, Markus, Behrens, Georg M N, Arora, Prerna, Kempf, Amy, Nehlmeier, Inga, Cossmann, Anne, Manthey, Luis, Dopfer-Jablonka, Alexandra, Pöhlmann, Stefan

“…In particular, the omicron variant (B.1.1.529 lineage and sublineages) is highly mutated and efficiently evades antibodies.1–3 Therefore, bivalent mRNA…”
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Amino acids, post-translational modifications, nitric oxide, and oxidative stress in serum and urine of long COVID and ex COVID human subjects by Mikuteit, Marie, Baskal, Svetlana, Klawitter, Sandra, Dopfer-Jablonka, Alexandra, Behrens, Georg M. N., Müller, Frank, Schröder, Dominik, Klawonn, Frank, Steffens, Sandra, Tsikas, Dimitrios

“…In this study, we investigated the status of amino acids, their post-translational modifications (PTM), major nitric oxide (NO) metabolites and of…”
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Profound neutralization evasion and augmented host cell entry are hallmarks of the fast-spreading SARS-CoV-2 lineage XBB.1.5 by Hoffmann, Markus, Arora, Prerna, Nehlmeier, Inga, Kempf, Amy, Cossmann, Anne, Schulz, Sebastian R., Morillas Ramos, Gema, Manthey, Luis A., Jäck, Hans-Martin, Behrens, Georg M. N., Pöhlmann, Stefan

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SARS-CoV-2 Omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodies by Arora, Prerna, Zhang, Lu, Krüger, Nadine, Rocha, Cheila, Sidarovich, Anzhalika, Schulz, Sebastian, Kempf, Amy, Graichen, Luise, Moldenhauer, Anna-Sophie, Cossmann, Anne, Dopfer-Jablonka, Alexandra, Behrens, Georg M.N., Jäck, Hans-Martin, Pöhlmann, Stefan, Hoffmann, Markus

“…The Omicron variant of SARS-CoV-2 evades antibody-mediated neutralization with unprecedented efficiency. At least three Omicron sublineages have been…”
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Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods by Bošnjak, Berislav, Stein, Saskia Catherina, Willenzon, Stefanie, Cordes, Anne Katrin, Puppe, Wolfram, Bernhardt, Günter, Ravens, Inga, Ritter, Christiane, Schultze-Florey, Christian R., Gödecke, Nina, Martens, Jörg, Kleine-Weber, Hannah, Hoffmann, Markus, Cossmann, Anne, Yilmaz, Mustafa, Pink, Isabelle, Hoeper, Marius M., Behrens, Georg M. N., Pöhlmann, Stefan, Blasczyk, Rainer, Schulz, Thomas F., Förster, Reinhold

“…Neutralizing antibodies targeting the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) block severe acute respiratory syndrome coronavirus 2…”
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Close to Zero, but Not Zero: What Is an Acceptable HIV Transmission Risk Through Breastfeeding? by Behrens, Georg M. N., Aebi-Popp, Karoline, Babiker, Abdel

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Measles, mumps, rubella, and varicella seroprevalence in refugees in Germany in 2015 by Jablonka, Alexandra, Happle, Christine, Grote, Ulrike, Schleenvoigt, Benjamin Thomas, Hampel, Annika, Dopfer, Christian, Hansen, Gesine, Schmidt, Reinhold Ernst, Behrens, Georg M. N.

“…Purpose The current extent of migration poses emerging socio–economic and humanitarian challenges. Little is known on vaccination rates in migrants entering…”
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2022 EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in adults with autoimmune inflammatory rheumatic diseases by Fragoulis, George E, Nikiphorou, Elena, Dey, Mrinalini, Zhao, Sizheng Steven, Courvoisier, Delphine Sophie, Arnaud, Laurent, Atzeni, Fabiola, Behrens, Georg Mn, Bijlsma, Johannes Wj, Böhm, Peter, Constantinou, Costas A, Garcia-Diaz, Silvia, Kapetanovic, Meliha Crnkic, Lauper, Kim, Luís, Mariana, Morel, Jacques, Nagy, György, Polverino, Eva, van Rompay, Jef, Sebastiani, Marco, Strangfeld, Anja, de Thurah, Annette, Galloway, James, Hyrich, Kimme L

“…To develop EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in patients with autoimmune inflammatory rheumatic…”
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Hypophosphatemia in people with HIV: no benefit when switching from tenofovir disoproxil fumarate to tenfovir alafenamide by Sandmann, Lisa, Stoll, Matthias, Behrens, Georg M.N.

“…Treatment with tenofovir disoproxil fumarate (TDF) has been associated with hypophosphatemia mainly because of injury of the renal proximal tubulus. Studies on…”
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Diminishing Immune Responses against Variants of Concern in Dialysis Patients 4 Months after SARS-CoV-2 mRNA Vaccination by Dulovic, Alex, Strengert, Monika, Ramos, Gema Morillas, Becker, Matthias, Griesbaum, Johanna, Junker, Daniel, Lürken, Karsten, Beigel, Andrea, Wrenger, Eike, Lonnemann, Gerhard, Cossmann, Anne, Stankov, Metodi V, Dopfer-Jablonka, Alexandra, Kaiser, Philipp D, Traenkle, Bjoern, Rothbauer, Ulrich, Krause, Gérard, Schneiderhan-Marra, Nicole, Behrens, Georg M N

“…Patients undergoing chronic hemodialysis were among the first to receive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations because of…”
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Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells by Klose, Johannes, Stankov, Metodi V, Kleine, Moritz, Ramackers, Wolf, Panayotova-Dimitrova, Diana, Jäger, Mark D, Klempnauer, Jürgen, Winkler, Michael, Bektas, Hüseyin, Behrens, Georg M N, Vondran, Florian W R

“…Salinomycin raised hope to be effective in anti-cancer therapies due to its capability to overcome apoptosis-resistance in several types of cancer cells…”
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Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination by Hammerschmidt, Swantje I., Bosnjak, Berislav, Bernhardt, Günter, Friedrichsen, Michaela, Ravens, Inga, Dopfer-Jablonka, Alexandra, Hoffmann, Markus, Pöhlmann, Stefan, Behrens, Georg M. N., Förster, Reinhold

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Neutralisation sensitivity of the SARS-CoV-2 XBB.1 lineage by Arora, Prerna, Cossmann, Anne, Schulz, Sebastian R, Ramos, Gema Morillas, Stankov, Metodi V, Jäck, Hans-Martin, Behrens, Georg M N, Pöhlmann, Stefan, Hoffmann, Markus

“…Co-infection with multiple SARS-CoV-2 lineages can result in recombination of the viral genomes and the emergence of novel, recombinant SARS-CoV-2 lineages.1–4…”
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Major revision version 11.0 of the European AIDS Clinical Society Guidelines 2021 by Ryom, Lene, De Miguel, Rosa, Cotter, Aoife Grace, Podlekareva, Daria, Beguelin, Charles, Waalewijn, Hylke, Arribas, Josè R, Mallon, Patrick W. G., Marzolini, Catia, Kirk, Ole, Bamford, Alasdair, Rauch, Andri, Molina, Jean Michel, Kowalska, Justyna Dominika, Guaraldi, Giovanni, Winston, Alan, Boesecke, Christoph, Cinque, Paola, Welch, Steven, Collins, Simon, Behrens, Georg M. N.

“…Background The European AIDS Clinical Society (EACS) Guidelines were revised in 2021 for the 17th time with updates on all aspects of HIV care. Key points of…”
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