Search Results - "BEGHEIN, Nelson"

Thalidomide Radiosensitizes Tumors through Early Changes in the Tumor Microenvironment by ANSIAUX, Réginald, BAUDELET, Christine, JORDAN, Bénédicte F, BEGHEIN, Nelson, SONVEAUX, Pierre, DE WEVER, Julie, MARTINIVE, Philippe, GREGOIRE, Vincent, FERON, Olivier, GALLEZ, Bernard

“…Purpose: The aim of this work was to study changes in the tumor microenvironment early after an antiangiogenic treatment using thalidomide (a promising…”
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Early reoxygenation in tumors after irradiation: determining factors and consequences for radiotherapy regimens using daily multiple fractions by Crokart, Nathalie, Jordan, Bénédicte F, Baudelet, Christine, Ansiaux, Reginald, Sonveaux, Pierre, Grégoire, Vincent, Beghein, Nelson, DeWever, Julie, Bouzin, Caroline, Feron, Olivier, Gallez, Bernard

“…To characterize changes in the tumor microenvironment early after irradiation and determine the factors responsible for early reoxygenation. Fibrosarcoma type…”
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Nitric oxide as a radiosensitizer: Evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption by Jordan, Bénédicte F., Sonveaux, Pierre, Feron, Olivier, Grégoire, Vincent, Beghein, Nelson, Dessy, Chantal, Gallez, Bernard

“…Different nitric oxide (NO)‐mediated treatments (e.g., isosorbide dinitrate, insulin and electrical stimulation of the host tissue) have been investigated for…”
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Glucocorticoids Modulate Tumor Radiation Response through a Decrease in Tumor Oxygen Consumption by Crokart, Nathalie, Jordan, Bénédicte F, Baudelet, Christine, Cron, Gregory O, Hotton, Julie, Radermacher, Kim, Grégoire, Vincent, Beghein, Nelson, Martinive, Philippe, Bouzin, Caroline, Feron, Olivier, Gallez, Bernard

“…Purpose: We hypothesized that glucocorticoids may enhance tumor radiosensitivity by increasing tumor oxygenation ( p O 2 ) through inhibition of mitochondrial…”
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Botulinum toxin potentiates cancer radiotherapy and chemotherapy by ANSIAUX, Réginald, BAUDELET, Christine, GREGOIRE, Vincent, BUC CALDERON, Pedro, FERON, Olivier, GALLEZ, Bernard, CRON, Greg O, SEGERS, Jérome, DESSY, Chantal, MARTINIVE, Philippe, DE WEVER, Julie, VERRAX, Julien, WAUTHIER, Valérie, BEGHEIN, Nelson

“…PURPOSE: Structural and functional abnormalities in the tumor vascular network are considered factors of resistance of solid tumors to cytotoxic treatments. To…”
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Contribution of oxygenation to BOLD contrast in exercising muscle by Jordan, Bénédicte F., Kimpalou, José Zéfu, Beghein, Nelson, Dessy, Chantal, Feron, Olivier, Gallez, Bernard

“…The potential physiological and therapeutic applications of functional MRI (fMRI) in skeletal muscle will depend on our ability to identify factors that may…”
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Development and evaluation of biocompatible inks for the local measurement of oxygen using in vivo EPR by Charlier, Nicolas, Beghein, Nelson, Gallez, Bernard

“…In vivo EPR oximetry is a powerful minimally invasive method that allows the measurement of oxygen in tissues through the use of a paramagnetic probe. In the…”
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Potentiation of radiation‐induced regrowth delay by isosorbide dinitrate in FSaII murine tumors by Jordan, Bénédicte F., Beghein, Nelson, Aubry, Marianne, Grégoire, Vincent, Gallez, Bernard

“…Oxygen deficiency in tumors reduces the efficacy of nonsurgical treatment modalities such as conventional radiotherapy and chemotherapy. Since tumor perfusion…”
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19F NMR in vivo spectroscopy reflects the effectiveness of perfusion-enhancing vascular modifiers for improving gemcitabine chemotherapy by Cron, Greg O., Beghein, Nelson, Ansiaux, Réginald, Martinive, Philippe, Feron, Olivier, Gallez, Bernard

“…Nuclear magnetic resonance spectroscopy of fluorine‐19 (19F NMR) has proven useful for evaluating kinetics of fluorinated chemotherapy drugs in tumors in vivo…”
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In Vivo Detection of Inflammation Using Pegylated Iron Oxide Particles Targeted at E-Selectin: A Multimodal Approach Using MR Imaging and EPR Spectroscopy by Radermacher, Kim A, Beghein, Nelson, Boutry, Sebastien, Laurent, Sophie, Elst, Luce Vander, Muller, Robert N, Jordan, Benedicte F, Gallez, Bernard

“…OBJECTIVES:Ultrasmall particles of iron oxide (USPIO) possess superparamagnetic properties and are used as negative contrast agent in magnetic resonance…”
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Tumor radiosensitization by antiinflammatory drugs : Evidence for a new mechanism involving the oxygen effect by CROKART, Nathalie, RADERMACHER, Kim, JORDAN, Bénédicte F, BAUDELET, Christine, CRON, Gregory O, GREGOIRE, Vincent, BEGHEIN, Nelson, BOUZIN, Caroline, FERON, Olivier, GALLEZ, Bernard

“…We hypothesized that nonsteroidal antiinflammatory drugs (NSAIDs) might enhance tumor radiosensitivity by increasing tumor oxygenation (pO2), via either a…”
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Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study by Verrax, Julien, Delvaux, Marianne, Beghein, Nelson, Taper, Henryk, Gallez, Bernard, Buc Calderon, Pedro

“…Since the higher redox potential of quinone molecules has been correlated with enhanced cellular deleterious effects, we studied the ability of the association…”
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Carbon blacks as EPR sensors for localized measurements of tissue oxygenation by Lan, Minbo, Beghein, Nelson, Charlier, Nicolas, Gallez, Bernard

“…New electron paramagnetic resonance (EPR) oximetry probes were identified in the class of carbon black materials. These compounds exhibit very high oxygen…”
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Changes in tumor oxygenation/perfusion induced by the no donor, isosorbide dinitrate, in comparison with carbogen: monitoring by EPR and MRI by Jordan, B F, Misson, P, Demeure, R, Baudelet, C, Beghein, N, Gallez, B

“…In an effort to improve radiotherapy treatments, methods aimed at increasing the quantity of oxygen delivered to tumors were investigated. The aim of this…”
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Assessment of liver phagocytic activity using EPR spectrometry and imaging by Charlier, Nicolas, Neyrinck, Audrey M, Beghein, Nelson, Delzenne, Nathalie M, Gallez, Bernard

“…Abstract The aim of the present study was to evaluate the usefulness of electron paramagnetic resonance (EPR) spectroscopy and imaging in assessing the…”
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Original contribution: Assessment of liver phagocytic activity using EPR spectrometry and imaging by Charlier, Nicolas, Neyrinck, Audrey M, Beghein, Nelson, Delzenne, Nathalie M, Gallez, Bernard

“…The aim of the present study was to evaluate the usefulness of electron paramagnetic resonance (EPR) spectroscopy and imaging in assessing the phagocytic…”
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Changes in the tumor microenvironment during low-dose-rate permanent seed implantation iodine-125 brachytherapy by Cron, Greg O, Beghein, Nelson, Crokart, Nathalie, Chavée, Emilie, Bernard, Sabine, Vynckier, Stefaan, Scalliet, Pierre, Gallez, Bernard

“…There is a lack of data regarding how the tumor microenvironment (e.g., perfusion and oxygen partial pressure [pO2]) changes in response to low-dose-rate (LDR)…”
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19 F NMR in vivo spectroscopy reflects the effectiveness of perfusion‐enhancing vascular modifiers for improving gemcitabine chemotherapy by Cron, Greg O., Beghein, Nelson, Ansiaux, Réginald, Martinive, Philippe, Feron, Olivier, Gallez, Bernard

“…Abstract Nuclear magnetic resonance spectroscopy of fluorine‐19 ( 19 F NMR) has proven useful for evaluating kinetics of fluorinated chemotherapy drugs in…”
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Preclinical safety and antitumor efficacy of insulin combined with irradiation by Jordan, Bénédicte F., Beghein, Nelson, Crokart, Nathalie, Baudelet, Christine, Grégoire, Vincent, Gallez, Bernard

“…We have previously reported that insulin significantly enhances tumor oxygenation ( pO 2) and increases radiation-induced tumor regrowth delay in experimental…”
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Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses by Jordan, Bénédicte F, Sonveaux, Pierre, Feron, Olivier, Grégoire, Vincent, Beghein, Nelson, Gallez, Bernard

“…Oxygen deficiency in tumors reduces the efficacy of nonsurgical treatment modalities. We tested the hypothesis that electrical stimulation of the sciatic nerve…”
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