Search Results - "BEER, Frederick"
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Serum Amyloid A is not obligatory for high-fat, high-sucrose, cholesterol-fed diet-induced obesity and its metabolic and inflammatory complications
Published in PloS one (18-04-2022)“…Several studies in the past have reported positive correlations between circulating Serum amyloid A (SAA) levels and obesity. However, based on limited number…”
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Antisense oligonucleotide targeting hepatic Serum Amyloid A limits the progression of angiotensin II-induced abdominal aortic aneurysm formation
Published in Atherosclerosis (01-04-2024)“…Obesity increases the risk for abdominal aortic aneurysms (AAA) in humans and enhances angiotensin II (AngII)-induced AAA formation in C57BL/6 mice. We…”
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Hebrews 5:5–10: A synthesis for the hermeneutical challenge in Pentecostalism on suffering?
Published in In die skriflig : tydskrif van die Gereformeerde Teologiese Vereniging (15-11-2024)“…Pentecostals adopt a distinct hermeneutical approach when reading and interpreting the Bible, emphasising the New Testament more than the Old Testament and,…”
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Serum amyloid A3 is a high density lipoprotein-associated acute-phase protein
Published in Journal of lipid research (01-02-2018)“…Serum amyloid A (SAA) is a family of acute-phase reactants. Plasma levels of human SAA1/SAA2 (mouse SAA1.1/2.1) can increase ≥1,000-fold during an acute-phase…”
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5
Serum amyloid A3 is pro-atherogenic
Published in Atherosclerosis (01-01-2018)“…Serum amyloid A (SAA) predicts cardiovascular events. Overexpression of SAA increases atherosclerosis development; however, deficiency of two of the murine…”
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Serum amyloid A impairs the antiinflammatory properties of HDL
Published in The Journal of clinical investigation (01-01-2016)“…HDL from healthy humans and lean mice inhibits palmitate-induced adipocyte inflammation; however, the effect of the inflammatory state on the functional…”
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Serum Amyloid A Is an Exchangeable Apolipoprotein
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2018)“…OBJECTIVE—SAA (serum amyloid A) is a family of acute-phase reactants that have proinflammatory and proatherogenic activities. SAA is more lipophilic than…”
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Serum amyloid A augments the atherogenic effects of cholesteryl ester transfer protein
Published in Journal of lipid research (01-05-2023)“…Serum amyloid A (SAA) is predictive of CVD in humans and causes atherosclerosis in mice. SAA has many proatherogenic effects in vitro. However, HDL, the major…”
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SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance
Published in The Journal of clinical investigation (01-01-2008)“…Septic shock results from an uncontrolled inflammatory response, mediated primarily by LPS. Cholesterol transport plays an important role in the host response…”
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10
Serum amyloid A is not incorporated into HDL during HDL biogenesis[S]
Published in Journal of lipid research (01-03-2020)“…Liver-derived serum amyloid A (SAA) is present in plasma where it is mainly associated with HDL and from which it is cleared more rapidly than are the other…”
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Deficiency of Acute-Phase Serum Amyloid A Exacerbates Sepsis-Induced Mortality and Lung Injury in Mice
Published in International journal of molecular sciences (15-12-2023)“…Serum amyloid A (SAA) is a family of proteins, the plasma levels of which may increase >1000-fold in acute inflammatory states. We investigated the role of SAA…”
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Adipocyte-Derived Serum Amyloid A Promotes Angiotensin II–Induced Abdominal Aortic Aneurysms in Obese C57BL/6J Mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2022)“…Obesity increases the risk for human abdominal aortic aneurysms (AAAs) and enhances Ang II (angiotensin II)-induced AAA formation in C57BL/6J mice. Obesity is…”
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13
Intestinal epithelial serum amyloid A modulates bacterial growth in vitro and pro-inflammatory responses in mouse experimental colitis
Published in BMC gastroenterology (10-11-2010)“…Serum Amyloid A (SAA) is a major acute phase protein of unknown function. SAA is mostly expressed in the liver, but also in other tissues including the…”
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High-Density Lipoprotein Suppresses the Type I Interferon Response, a Family of Potent Antiviral Immunoregulators, in Macrophages Challenged With Lipopolysaccharide
Published in Circulation (New York, N.Y.) (09-11-2010)“…High-density lipoprotein (HDL) protects the artery wall by removing cholesterol from lipid-laden macrophages. However, recent evidence suggests that HDL might…”
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15
HDL Remodeling During the Acute Phase Response
Published in Arteriosclerosis, thrombosis, and vascular biology (01-02-2009)“…OBJECTIVE—The purpose of this study was to examine the interactive action of serum amyloid A (SAA), group IIA secretory phospholipase A2 (sPLA2-IIA), and…”
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Serum Amyloid A Promotes Inflammation-Associated Damage and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
Published in Cellular and molecular gastroenterology and hepatology (01-01-2021)“…Identifying new approaches to lessen inflammation, as well as the associated malignant consequences, remains crucial to improving the lives and prognosis of…”
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A Murine Model of Obesity With Accelerated Atherosclerosis
Published in Obesity (Silver Spring, Md.) (01-01-2010)“…The epidemic of obesity sweeping developed nations is accompanied by an increase in atherosclerotic cardiovascular diseases. Dyslipidemia, diabetes,…”
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Inflammation and Tumor Progression: The Differential Impact of SAA in Breast Cancer Models
Published in Biology (Basel, Switzerland) (01-09-2024)“…Previous research has shown that the Serum Amyloid A (SAA) protein family is intricately involved in inflammatory signaling and various disease pathologies. We…”
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The ecclesiastical difficulty of Ephesians 4:1–6 in view of the different perspectives on the baptism in the Holy Spirit and the gifts of the Holy Spirit
Published in In die skriflig : tydskrif van die Gereformeerde Teologiese Vereniging (01-01-2020)“…Abstract only…”
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Impact of individual acute phase serum amyloid A isoforms on HDL metabolism in mice[S]
Published in Journal of lipid research (01-06-2016)“…The acute phase (AP) reactant serum amyloid A (SAA), an HDL apolipoprotein, exhibits pro-inflammatory activities, but its physiological function(s) are poorly…”
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