Search Results - "BEECHEY, C. V"

Imprinted expression of the murine Angelman syndrome gene, Ube3a , in hippocampal and Purkinje neurons by Albrecht, Urs, Sutcliffe, James S, Cattanach, Bruce M, Beechey, Colin V, Armstrong, Dawna, Eichele, Gregor, Beaudet, Arthur L

“…Angelman syndrome (AS) is a human genetic disorder characterized by mental retardation, seizures, inappropriate laughter, abnormal galt, tremor and ataxia…”
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Embryological and molecular investigations of parental imprinting on mouse chromosome 7 by Ferguson-Smith, A. C, Cattanach, B. M, Barton, S. C, Beechey, C. V, Surani, M. A

“…Mouse embryos with duplications of whole maternal (parthenogenetic and gynogenetic) or paternal (androgenetic) genomes show reciprocal phenotypes and do not…”
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Interactions between imprinting effects: summary and review by Cattanach, B M, Beechey, C V, Peters, J

“…Mice with uniparental disomies (uniparental duplications) for defined regions of certain chromosomes, or certain disomies, show a range of developmental…”
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A candidate model for Angelman syndrome in the mouse by Cattanach, B M, Barr, J A, Beechey, C V, Martin, J, Noebels, J, Jones, J

“…Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are well-recognized examples of imprinting in humans. They occur most commonly with paternal and…”
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Identification of Imprinted Loci by Methylation-Sensitive Representational Difference Analysis: Application to Mouse Distal Chromosome 2 by Kelsey, Gavin, Bodle, Dorothy, Miller, Howard J., Beechey, Colin V., Coombes, Candice, Peters, Josephine, Williamson, Christine M.

“…Imprinted genes are distinguished by different patterns of methylation on their parental alleles, a property by which imprinted loci could be identified…”
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Imprinting control within the compact Gnas locus by Peters, J, Holmes, R, Monk, D, Beechey, C V, Moore, G E, Williamson, C M

“…Mouse distal chromosome 2 was one of the earliest described imprinting regions. Maternal and paternal inheritance of the region is associated with opposite…”
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A reassessment of imprinting regions and phenotypes on mouse chromosome 6: Nap1l5 locates within the currently defined sub-proximal imprinting region by Beechey, C V

“…Previous studies (Beechey, 2000) have shown that mouse proximal chromosome (Chr) 6 has two imprinting regions. An early embryonic lethality is associated with…”
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Autosomal and X-chromosome imprinting by CATTANACH, B. M, BEECHEY, C. V

“…Mouse genetic studies using Robertsonian and reciprocal translations have shown that certain autosomal regions of loci are subject to a parental germ line…”
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Association of a redefined proximal mouse chromosome 11 imprinting region and U2afbp-rs/U2af1-rs1 expression by Cattanach, B M, Shibata, H, Hayashizaki, Y, Townsend, K M, Ball, S, Beechey, C V

“…Mice with maternal and paternal disomy for chromosome 11 (Chr 11) show growth retarded and overgrowth phenotypes, respectively, which can be attributed to…”
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Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark by Arnaud, Philippe, Monk, David, Hitchins, Megan, Gordon, Emma, Dean, Wendy, Beechey, Colin V., Peters, Jo, Craigen, William, Preece, Michael, Stanier, Philip, Moore, Gudrun E., Kelsey, Gavin

“…Grb10/GRB10 encodes a cytoplasmic adapter protein which modulates coupling of a number of cell surface receptor tyrosine kinases with specific signalling…”
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Localisation of the imprinted gene neuronatin, Nnat, confirms and refines the location of a second imprinting region on mouse chromosome 2 by Williamson, C M, Beechey, C V, Ball, S T, Dutton, E R, Cattanach, B M, Tease, C, Ishino, F, Peters, J

“…Nine regions on six mouse autosomes are subject to imprinting and uniparental inheritance of any one of these regions results in mice with phenotypic…”
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A Cluster of Oppositely Imprinted Transcripts at the Gnas Locus in the Distal Imprinting Region of Mouse Chromosome 2 by Peters, Jo, Wroe, Stephanie F., Wells, Christine A., Miller, Howard J., Bodle, Dorothy, Beechey, Colin V., Williamson, Christine M., Kelsey, Gavin

“…Imprinted genes tend to occur in clusters. We have identified a cluster in distal mouse chromosome (Chr) 2, known from early genetic studies to contain both…”
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The Mouse Murr1 Gene Is Imprinted in the Adult Brain, Presumably Due to Transcriptional Interference by the Antisense-Oriented U2af1-rs1 Gene by Wang, Youdong, Joh, Keiichiro, Masuko, Sadahiko, Yatsuki, Hitomi, Soejima, Hidenobu, Nabetani, Akira, Beechey, Colin V., Okinami, Satoshi, Mukai, Tsunehiro

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Peg1/Mest locates distal to the currently defined imprinting region on mouse proximal chromosome 6 and identifies a new imprinting region affecting growth by Beechey, C V

“…Mice with maternal duplication for proximal chromosome 6 (Chr 6) die in utero before 11.5 dpc, an effect that can be attributed to genomic imprinting. Previous…”
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An Imprinted Transcript, Antisense to Nesp, Adds Complexity to the Cluster of Imprinted Genes at the Mouse Gnas Locus by Wroe, Stephanie F., Kelsey, Gavin, Skinner, Judith A., Bodle, Dorothy, Ball, Simon T., Beechey, Colin V., Peters, Josephine, Williamson, Christine M.

“…The Gnas locus in distal mouse chromosome (Chr) 2 is emerging as a complex genomic region. It contains three imprinted genes in the order Nesp-Gnasxl-Gnas…”
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Appendix: imprinted genes and regions in mouse and human by Beechey, C V

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The mouse Zac1 locus: basis for imprinting and comparison with human ZAC by Smith, Rachel J, Arnaud, Philippe, Konfortova, Galia, Dean, Wendy L, Beechey, Colin V, Kelsey, Gavin

“…We identified a maternally methylated CpG island at the mouse Zac1 locus on chromosome (Chr.) 10 in a screen for imprinted genes. The homologous human gene ZAC…”
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Imprinted genes: identification by chromosome rearrangements and post-genomic strategies by Oakey, Rebecca J., Beechey, Colin V.

“…Imprinted genes are differentially expressed from the maternally and paternally inherited alleles. Accordingly, inheritance of both copies of an imprinted…”
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T(In1;5)44H, a complex mouse chromosomal rearrangement with a phenotypic effect by Evans, E P, Beechey, C V, Burtenshaw, M D, Searle, A G

“…A complex murine chromosomal rearrangement, T(In1;5)44H, was recovered after 5 Gy + 5 Gy (given 24 h apart) spermatogonial X-irradiation. T44H is a paracentric…”
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Male pachytene pairing in single and double translocation heterozygotes and spermatogenic impairment in the mouse by DE BOER, P, SEARLE, A. G, VAN DER HOEVEN, F. A, DE ROOIJ, D. G, BEECHEY, C. V

“…In order to clarify the relationship between meiotic pairing and progress of spermatogenesis, an analysis of male meiotic pairing was carried out in four…”
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