Search Results - "BECKMAN, B"
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Systematic improvement of amplicon marker gene methods for increased accuracy in microbiome studies
Published in Nature biotechnology (01-09-2016)“…Sources of error and bias in PCR amplification of microbial samples for 16S rRNA gene sequencing are systematically evaluated, and best-practice…”
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A rapid, cost-effective tailed amplicon method for sequencing SARS-CoV-2
Published in BMC genomics (04-12-2020)“…The global COVID-19 pandemic has led to an urgent need for scalable methods for clinical diagnostics and viral tracking. Next generation sequencing…”
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Evaluating the Information Content of Shallow Shotgun Metagenomics
Published in mSystems (01-11-2018)“…Although microbial communities are associated with human, environmental, plant, and animal health, there exists no cost-effective method for precisely…”
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4
Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals
Published in Genome research (01-01-2014)“…Understanding the consequences of regulatory variation in the human genome remains a major challenge, with important implications for understanding gene…”
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5
Dissecting and tuning primer editing by proofreading polymerases
Published in Nucleic acids research (07-09-2021)“…Abstract Proofreading polymerases have 3′ to 5′ exonuclease activity that allows the excision and correction of mis-incorporated bases during DNA replication…”
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The impact of a program in mindful communication on primary care physicians
Published in Academic medicine (01-06-2012)“…In addition to structural transformations, deeper changes are needed to enhance physicians' sense of meaning and satisfaction with their work and their ability…”
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Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-08-2021)“…Abstract Background Age and disease prevalence are the 2 biggest risk factors for Coronavirus disease 2019 (COVID-19) symptom severity and death. We therefore…”
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Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
Published in Nature communications (06-06-2019)“…Genetic factors underlying leukocyte telomere length (LTL) may provide insights into telomere homeostasis, with direct links to disease susceptibility. Genetic…”
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Measuring sequencer size bias using REcount: a novel method for highly accurate Illumina sequencing-based quantification
Published in Genome Biology (29-04-2019)“…Quantification of DNA sequence tags from engineered constructs such as plasmids, transposons, or other transgenes underlies many functional genomics…”
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10
The Free Radical Theory of Aging Matures
Published in Physiological reviews (01-04-1998)“…KENNETH B. BECKMAN AND BRUCE N. AMES Department of Molecular and Cell Biology, University of California, Berkeley, California Beckman, Kenneth B., and Bruce…”
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AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
Published in Oncogene (08-11-2012)“…Reactivation of the androgen receptor (AR) during androgen depletion therapy (ADT) underlies castration-resistant prostate cancer (CRPCa). Alternative splicing…”
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12
Evidence for depressed growth of juvenile Pacific salmon (Oncorhynchus) in Johnstone and Queen Charlotte Straits, British Columbia
Published in Fisheries oceanography (01-03-2018)“…Juvenile salmon traveling northwestward to the Pacific Ocean from the Strait of Georgia migrate through and take residence in both Johnstone and Queen…”
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13
Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore
Published in British journal of nutrition (14-02-2013)“…Vitamin D is known for maintaining Ca homeostasis and bone structure, and may also decrease susceptibility to chronic and infectious diseases. However, data on…”
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Leukocyte telomere length in relation to risk of lung adenocarcinoma incidence: Findings from the Singapore Chinese Health Study
Published in International journal of cancer (01-06-2018)“…Telomeres are crucial in the maintenance of chromosome integrity and genomic stability. Critically short telomeres can trigger programed cell death while cells…”
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Physicians' perceptions of autonomy support during transition to value-based reimbursement: A multi-center psychometric evaluation of six-item and three-item measures
Published in PloS one (01-04-2020)“…Successive health system reforms have steadily eroded physician autonomy. Escalating accountability demands placed on physicians concurrent with diminishing…”
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Previtellogenic Oocyte Growth in Salmon: Relationships among Body Growth, Plasma Insulin-Like Growth Factor-1, Estradiol-17beta, Follicle-Stimulating Hormone and Expression of Ovarian Genes for Insulin-Like Growth Factors, Steroidogenic-Acute Regulatory Protein and Receptors for Gonadotropins, Growth Hormone, and Somatolactin
Published in Biology of reproduction (01-07-2006)“…Body growth during critical periods is known to be an important factor in determining the age of maturity and fecundity in fish. However, the endocrine…”
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Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort
Published in PloS one (02-10-2019)“…The mitochondrial genome encodes for thirty-seven proteins, among them thirteen are essential for the oxidative phosphorylation (OXPHOS) system. Inherited…”
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Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort
Published in PloS one (04-09-2015)“…The mitochondrial genome encodes for the synthesis of 13 proteins that are essential for the oxidative phosphorylation (OXPHOS) system. Inherited variation in…”
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Soliciting the Patient's Agenda: Have We Improved?
Published in JAMA : the journal of the American Medical Association (20-01-1999)“…CONTEXT Previous research indicates physicians frequently choose a patient problem to explore before determining the patient's full spectrum of concerns…”
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Persistent microbial dysbiosis in preterm premature rupture of membranes from onset until delivery
Published in PeerJ (San Francisco, CA) (26-11-2015)“…Background. Preterm Premature Rupture of Membranes (PPROM) is a major leading cause of preterm births. While the cause for PPROM remains unidentified, it is…”
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