Search Results - "BECKER, Natalia"

c060 : Extended Inference with Lasso and Elastic-Net Regularized Cox and Generalized Linear Models by Sill, Martin, Hielscher, Thomas, Becker, Natalia, Zucknick, Manuela

“…We have developed the R package c060 with the aim of improving R software func- tionality for high-dimensional risk prediction modeling, e.g., for prognostic…”
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Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data by Becker, Natalia, Toedt, Grischa, Lichter, Peter, Benner, Axel

“…Classification and variable selection play an important role in knowledge discovery in high-dimensional data. Although Support Vector Machine (SVM) algorithms…”
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Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients by ZEPPERNICK, Felix, AHMADI, Rezvan, CAMPOS, Benito, DICTUS, Christine, HELMKE, Burkhard M, BECKER, Natalia, LICHTER, Peter, UNTERBERG, Andreas, RADLWIMMER, Bernhard, HEROLD-MENDE, Christel C

“…Purpose: The CD133 antigen has been identified as a putative stem cell marker in normal and malignant brain tissues. In gliomas, it is used to enrich a…”
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Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway by Goeppert, Benjamin, Konermann, Carolin, Schmidt, Christopher Roman, Bogatyrova, Olga, Geiselhart, Lea, Ernst, Christina, Gu, Lei, Becker, Natalia, Zucknick, Manuela, Mehrabi, Arianeb, Hafezi, Mohammadreza, Klauschen, Frederick, Stenzinger, Albrecht, Warth, Arne, Breuhahn, Kai, Renner, Marcus, Weichert, Wilko, Schirmacher, Peter, Plass, Christoph, Weichenhan, Dieter

“…The molecular mechanisms underlying the genesis of cholangiocarcinomas (CCs) are poorly understood. Epigenetic changes such as aberrant hypermethylation and…”
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BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas by Pfister, Stefan, Janzarik, Wibke G, Remke, Marc, Ernst, Aurélie, Werft, Wiebke, Becker, Natalia, Toedt, Grischa, Wittmann, Andrea, Kratz, Christian, Olbrich, Heike, Ahmadi, Rezvan, Thieme, Barbara, Joos, Stefan, Radlwimmer, Bernhard, Kulozik, Andreas, Pietsch, Torsten, Herold-Mende, Christel, Gnekow, Astrid, Reifenberger, Guido, Korshunov, Andrey, Scheurlen, Wolfram, Omran, Heymut, Lichter, Peter

“…The molecular pathogenesis of pediatric astrocytomas is still poorly understood. To further understand the genetic abnormalities associated with these tumors,…”
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penalizedSVM: a R-package for feature selection SVM classification by Becker, Natalia, Werft, Wiebke, Toedt, Grischa, Lichter, Peter, Benner, Axel

“…Support vector machine (SVMs) classification is a widely used and one of the most powerful classification techniques. However, a major limitation is that SVM…”
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LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem-Like Cells by Nakata, Susumu, Campos, Benito, Bageritz, Josephine, Lorenzo Bermejo, Justo, Becker, Natalia, Engel, Felix, Acker, Till, Momma, Stefan, Herold-Mende, Christel, Lichter, Peter, Radlwimmer, Bernhard, Goidts, Violaine

“…In various types of cancers including glioblastoma, accumulating evidence show the existence of cancer stem‐like cells (CSCs), characterized by stem cell…”
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SNPs in transporter and metabolizing genes as predictive markers for oxaliplatin treatment in colorectal cancer patients by Kap, Elisabeth J., Seibold, Petra, Scherer, Dominique, Habermann, Nina, Balavarca, Yesilda, Jansen, Lina, Zucknick, Manuela, Becker, Natalia, Hoffmeister, Michael, Ulrich, Alexis, Benner, Axel, Ulrich, Cornelia M., Burwinkel, Barbara, Brenner, Hermann, Chang‐Claude, Jenny

“…Oxaliplatin is frequently used as part of a chemotherapeutic regimen with 5‐fluorouracil in the treatment of colorectal cancer (CRC). The cellular availability…”
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Pharmacological Inhibition of Centrosome Clustering by Slingshot-Mediated Cofilin Activation and Actin Cortex Destabilization by Konotop, Gleb, Bausch, Elena, Nagai, Tomoaki, Turchinovich, Andrey, Becker, Natalia, Benner, Axel, Boutros, Michael, Mizuno, Kensaku, Krämer, Alwin, Raab, Marc Steffen

“…Centrosome amplification is a hallmark of virtually all types of cancers, including solid tumors and hematologic malignancies. Cancer cells with extra…”
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Lenalidomide/melphalan/dexamethasone in newly diagnosed patients with immunoglobulin light chain amyloidosis: results of a prospective phase 2 study with long-term follow up by Hegenbart, Ute, Bochtler, Tilmann, Benner, Axel, Becker, Natalia, Kimmich, Christoph, Kristen, Arnt V, Beimler, Jörg, Hund, Ernst, Zorn, Markus, Freiberger, Anja, Gawlik, Marianne, Goldschmidt, Hartmut, Hose, Dirk, Jauch, Anna, Ho, Anthony D, Schönland, Stefan O

“…Chemotherapy in light chain amyloidosis aims to normalize the involved free light chain in serum, which leads to an improvement, or at least stabilization of…”
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Which patients to sample in clinical cohort studies when the number of events is high and measurement of additional markers is constrained by limited resources by Edelmann, Dominic, Ohneberg, Kristin, Becker, Natalia, Benner, Axel, Schumacher, Martin

“…Purpose We consider an existing clinical cohort with events but limited resources for the investigation of a further potentially expensive marker. Biological…”
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Mental health care delivery and quality of service provision in Brazil by Marchionatti, Lauro Estivalete, Rocha, Kátia Bones, Becker, Natalia, Gosmann, Natan Pereira, Salum, Giovanni A.

“…Public mental health system in Brazil is structured through “The Psychosocial Care Network (Rede de Atenção Psicossocial, RAPS)". This coordinated system…”
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Developing a Digital Game to Enhance Social Cognition Skills in Adolescents With ASD in a Multidisciplinary Context by Farinazzo Martins, Valeria, Andriotti, Andre, de Oliveira, Carlos, Pezeiro, Rafael J., Domingues, Claudionor, Verissimo, Leonardo, Becker, Natalia

“…Autism Spectrum Disorder (ASD) is characterized by problems with social interactions and communication, and restricted or repetitive behaviors. Upon reaching…”
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Assessment of cognitive functioning using the Mini Mental State Examination in men with Alcohol and Crack Cocaine Use Disorder by Schuch, Jaqueline B, Becker, Natália, Rabelo-da-Ponte, Francisco Diego, Ornell, Felipe, Freitas, Hellen J M, Rebelatto, Fernando P, Sordi, Anne O, Pechansky, Flavio, von Diemen, Lisia, Kessler, Felix H P

“…The consumption of substances has been associated with cognitive impairment. The Mini Mental State Examination (MMSE) is an easy-to-apply screening used to…”
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Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling by Filarsky, Katharina, Garding, Angela, Becker, Natalia, Wolf, Christine, Zucknick, Manuela, Claus, Rainer, Weichenhan, Dieter, Plass, Christoph, Döhner, Hartmut, Stilgenbauer, Stephan, Lichter, Peter, Mertens, Daniel

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Memory and language impairments are associated with anxiety disorder severity in childhood by Sbicigo, Juliana B, Toazza, Rudineia, Becker, Natália, Ecker, Kimberly, Manfro, Gisele G, Salles, Jerusa F de

“…Introduction Children with anxiety disorders have been suggested to possess deficits in verbal fluency, shifting and attention, with inconsistent results…”
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Molecular signatures classify astrocytic gliomas by IDH1 mutation status by Toedt, Grischa, Barbus, Sebastian, Wolter, Marietta, Felsberg, Jörg, Tews, Björn, Blond, Frederic, Sabel, Michael C., Hofmann, Stefanie, Becker, Natalia, Hartmann, Christian, Ohgaki, Hiroko, von Deimling, Andreas, Wiestler, Otmar D., Hahn, Meinhard, Lichter, Peter, Reifenberger, Guido, Radlwimmer, Bernhard

“…To identify novel glioma‐associated pathomechanisms and molecular markers, we performed an array‐based comparative genomic hybridization analysis of 131…”
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Intragroup differences and similarities in performance on rapid automatized naming tasks in children with ADHD symptoms, children with reading disabilities, and controls by Koltermann, Gabriella, Becker, Natália, Wauke, Ana Paula Toome, de Oliveira, Cristiano Pereira, Gomides, Mariuche Rodrigues de Almeida, Paiva, Giulia Moreira, Haase, Vitor Geraldi, de Salles, Jerusa Fumagalli

“…Introduction Rapid automatized naming (RAN) is the ability to name, as fast as possible, symbols such as letters, digits and figures. The present study aimed…”
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Multiplex bead-based measurement of humoral immune responses against tumor-associated antigens in stage II melanoma patients of the EORTC18961 trial by Michels, Judith, Becker, Natalia, Suciu, Stefan, Kaiser, Iris, Benner, Axel, Kosaloglu-Yalcin, Zeynep, Agoussi, Sandrine, Halama, Niels, Pawlita, Michael, Waterboer, Tim, Eichmüller, Stefan B., Jäger, Dirk, Eggermont, Alexander M. M., Zörnig, Inka

“…Purpose: Determine the prognostic and predictive significance of tumor associated antigen (TAA)-specific serum antibodies in melanoma patients of a large…”
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Attention, memory, visuoconstructive, and executive task performance in adolescents with anxiety disorders: a case-control community study by Jarros, Rafaela Behs, Salum, Giovanni Abrahão, Silva, Cristiano Tschiedel Belem da, Toazza, Rudineia, Becker, Natália, Agranonik, Marilyn, Salles, Jerusa Fumagalli de, Manfro, Gisele Gus

“…The aim of the present study was to assess children and adolescents with mild and severe anxiety disorders for their performance in attention, verbal episodic…”
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