Search Results - "BECKER, Michelle M"

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen by Pallesen, Jesper, Wang, Nianshuang, Corbett, Kizzmekia S., Wrapp, Daniel, Kirchdoerfer, Robert N., Turner, Hannah L., Cottrell, Christopher A., Becker, Michelle M., Wang, Lingshu, Shi, Wei, Kong, Wing-Pui, Andres, Erica L., Kettenbach, Arminja N., Denison, Mark R., Chappell, James D., Graham, Barney S., Ward, Andrew B., McLellan, Jason S.

“…Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus that since its emergence in 2012 has caused outbreaks in human…”
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Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus by Huang, I-Chueh, Bailey, Charles C, Weyer, Jessica L, Radoshitzky, Sheli R, Becker, Michelle M, Chiang, Jessica J, Brass, Abraham L, Ahmed, Asim A, Chi, Xiaoli, Dong, Lian, Longobardi, Lindsay E, Boltz, Dutch, Kuhn, Jens H, Elledge, Stephen J, Bavari, Sina, Denison, Mark R, Choe, Hyeryun, Farzan, Michael

“…Interferon-inducible transmembrane proteins 1, 2, and 3 (IFITM1, 2, and 3) are recently identified viral restriction factors that inhibit infection mediated by…”
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Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing by Eckerle, Lance D, Becker, Michelle M, Halpin, Rebecca A, Li, Kelvin, Venter, Eli, Lu, Xiaotao, Scherbakova, Sana, Graham, Rachel L, Baric, Ralph S, Stockwell, Timothy B, Spiro, David J, Denison, Mark R

“…Most RNA viruses lack the mechanisms to recognize and correct mutations that arise during genome replication, resulting in quasispecies diversity that is…”
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Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape by Wang, Lingshu, Shi, Wei, Chappell, James D, Joyce, M Gordon, Zhang, Yi, Kanekiyo, Masaru, Becker, Michelle M, van Doremalen, Neeltje, Fischer, Robert, Wang, Nianshuang, Corbett, Kizzmekia S, Choe, Misook, Mason, Rosemarie D, Van Galen, Joseph G, Zhou, Tongqing, Saunders, Kevin O, Tatti, Kathleen M, Haynes, Lia M, Kwong, Peter D, Modjarrad, Kayvon, Kong, Wing-Pui, McLellan, Jason S, Denison, Mark R, Munster, Vincent J, Mascola, John R, Graham, Barney S

“…Middle East respiratory syndrome coronavirus (MERS-CoV) causes a highly lethal pulmonary infection with ∼35% mortality. The potential for a future pandemic…”
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Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD by Wang, Nianshuang, Rosen, Osnat, Wang, Lingshu, Turner, Hannah L., Stevens, Laura J., Corbett, Kizzmekia S., Bowman, Charles A., Pallesen, Jesper, Shi, Wei, Zhang, Yi, Leung, Kwanyee, Kirchdoerfer, Robert N., Becker, Michelle M., Denison, Mark R., Chappell, James D., Ward, Andrew B., Graham, Barney S., McLellan, Jason S.

“…Middle East respiratory syndrome coronavirus (MERS-CoV) emerged into the human population in 2012 and has caused substantial morbidity and mortality. Potently…”
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Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice by Becker, Michelle M, Graham, Rachel L, Donaldson, Eric F, Rockx, Barry, Sims, Amy C, Sheahan, Timothy, Pickles, Raymond J, Corti, Davide, Johnston, Robert E, Baric, Ralph S, Denison, Mark R

“…Defining prospective pathways by which zoonoses evolve and emerge as human pathogens is critical for anticipating and controlling both natural and deliberate…”
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Coronavirus Replication Does Not Require the Autophagy Gene ATG5 by Zhao, Zijiang, Thackray, Larissa B., Miller, Brian C., Lynn, Teresa M., Becker, Michelle M., Ward, Eric, Mizushima, Noboru, Denison, Mark R., Virgin, IV, Herbert W.

“…Macroautophagy (herein autophagy) is a cellular process, requiring ATG5, by which cells deliver double membrane-bound packets containing cytoplasm or…”
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Nuclear Localization of Cytoplasmic Poly(A)-Binding Protein upon Rotavirus Infection Involves the Interaction of NSP3 with eIF4G and RoXaN by HARB, Maya, BECKER, Michelle M, VITOUR, Damien, BARON, Carolina H, VENDE, Patrice, BROWN, Spencer C, BOLTE, Susanne, AROLD, Stefan T, PONCET, Didier

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Coronaviruses induce entry-independent, continuous macropinocytosis by Freeman, Megan Culler, Peek, Christopher T, Becker, Michelle M, Smith, Everett Clinton, Denison, Mark R

“…Macropinocytosis is exploited by many pathogens for entry into cells. Coronaviruses (CoVs) such as severe acute respiratory syndrome (SARS) CoV and Middle East…”
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Reovirus σNS and μNS Proteins Form Cytoplasmic Inclusion Structures in the Absence of Viral Infection by Becker, Michelle M, Peters, Timothy R, Dermody, Terence S

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A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease by Graham, Rachel L, Becker, Michelle M, Eckerle, Lance D, Bolles, Meagan, Denison, Mark R, Baric, Ralph S

“…Attenuated viruses can be highly effective vaccines. In this issue, Ralph Baric and colleagues report that inactivating mutations in the exonuclease ExoN of a…”
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Evaluation of candidate vaccine approaches for MERS-CoV by Wang, Lingshu, Shi, Wei, Joyce, M. Gordon, Modjarrad, Kayvon, Zhang, Yi, Leung, Kwanyee, Lees, Christopher R., Zhou, Tongqing, Yassine, Hadi M., Kanekiyo, Masaru, Yang, Zhi-yong, Chen, Xuejun, Becker, Michelle M., Freeman, Megan, Vogel, Leatrice, Johnson, Joshua C., Olinger, Gene, Todd, John P., Bagci, Ulas, Solomon, Jeffrey, Mollura, Daniel J., Hensley, Lisa, Jahrling, Peter, Denison, Mark R., Rao, Srinivas S., Subbarao, Kanta, Kwong, Peter D., Mascola, John R., Kong, Wing-Pui, Graham, Barney S.

“…The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) as a cause of severe respiratory disease highlights the need for effective approaches…”
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Fine particulate matters: The impact of air quality standards on cardiovascular mortality by Corrigan, Anne E., Becker, Michelle M., Neas, Lucas M., Cascio, Wayne E., Rappold, Ana G.

“…In 1997 the U.S. Environmental Protection Agency set the first annual National Ambient Air Quality Standard (NAAQS) for fine particulate matter (PM2.5)…”
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RoXaN, a Novel Cellular Protein Containing TPR, LD, and Zinc Finger Motifs, Forms a Ternary Complex with Eukaryotic Initiation Factor 4G and Rotavirus NSP3 by VITOUR, Damien, LINDENBAUM, Pierre, VENDE, Patrice, BECKER, Michelle M, PONCET, Didier

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A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant by Agnihothram, Sudhakar, Yount, Jr, Boyd L, Donaldson, Eric F, Huynh, Jeremy, Menachery, Vineet D, Gralinski, Lisa E, Graham, Rachel L, Becker, Michelle M, Tomar, Sakshi, Scobey, Trevor D, Osswald, Heather L, Whitmore, Alan, Gopal, Robin, Ghosh, Arun K, Mesecar, Andrew, Zambon, Maria, Heise, Mark, Denison, Mark R, Baric, Ralph S

“…Cross-species transmission of zoonotic coronaviruses (CoVs) can result in pandemic disease outbreaks. Middle East respiratory syndrome CoV (MERS-CoV),…”
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Reovirus ςNS Protein Is Required for Nucleation of Viral Assembly Complexes and Formation of Viral Inclusions by Becker, Michelle M., Goral, Mehmet I., Hazelton, Paul R., Baer, Geoffrey S., Rodgers, Steven E., Brown, Earl G., Coombs, Kevin M., Dermody, Terence S.

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Fine particulate matters: The impact of air quality standards on cardiovascular mortality by Corrigan, Anne E., Becker, Michelle M., Neas, Lucas M., Cascio, Wayne E., Rappold, Ana G.

“…Highlights: • PM{sub 2.5} decreased following implementation of annual PM{sub 2.5} standard. • Cardiovascular mortality decreased with a decrease in PM{sub…”
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Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD by Wang, Nianshuang, Rosen, Osnat, Wang, Lingshu, Turner, Hannah L., Stevens, Laura J., Corbett, Kizzmekia S., Bowman, Charles A., Pallesen, Jesper, Shi, Wei, Zhang, Yi, Leung, Kwanyee, Kirchdoerfer, Robert N., Becker, Michelle M., Denison, Mark R., Chappell, James D., Ward, Andrew B., Graham, Barney S., McLellan, Jason S.

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Evaluation of candidate vaccine approaches for MERS-CoV by Wang, Lingshu, Shi, Wwi, Joyce, M. Gordon, Modjarrad, Kayvon, Zhang, Yi, Leung, Kwanyee, Lees, Christopher R., Zhou, Tongqing, Yassine, Hadi M., Kanekiyo, Masaru, Yang, Zhi-Yong, Chen, Xuejun, Becker, Michelle M., Freeman, Megan, Vogel, Leatrice, Johnson, Joshua C., Olinger, Gene, Todd, John P., Bagci, Ulas, Solomon, Jeffrey, Mollura, Daniel J., Hensley, Lisa, Jahrling, Peter, Denison, Mark R., Rao, Srinivas S., Subbarao, Kanta, Kwong, Peter D., Mascola, John R., Kong, Wing-Pui, Graham, Barney S.

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Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing: e1000896 by Eckerle, Lance D, Becker, Michelle M, Halpin, Rebecca A, Li, Kelvin, Venter, Eli, Lu, Xiaotao, Scherbakova, Sana, Graham, Rachel L, Baric, Ralph S, Stockwell, Timothy B, Spiro, David J, Denison, Mark R

“…Most RNA viruses lack the mechanisms to recognize and correct mutations that arise during genome replication, resulting in quasispecies diversity that is…”
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