Search Results - "BEARDEN, Carrie E"

Progressive Reduction in Cortical Thickness as Psychosis Develops: A Multisite Longitudinal Neuroimaging Study of Youth at Elevated Clinical Risk by Cannon, Tyrone D, Chung, Yoonho, He, George, Sun, Daqiang, Jacobson, Aron, van Erp, Theo G.M, McEwen, Sarah, Addington, Jean, Bearden, Carrie E, Cadenhead, Kristin, Cornblatt, Barbara, Mathalon, Daniel H, McGlashan, Thomas, Perkins, Diana, Jeffries, Clark, Seidman, Larry J, Tsuang, Ming, Walker, Elaine, Woods, Scott W, Heinssen, Robert

“…Abstract Background Individuals at clinical high risk (CHR) who progress to fully psychotic symptoms have been observed to show a steeper rate of cortical gray…”
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Towards a psychosis risk blood diagnostic for persons experiencing high-risk symptoms: preliminary results from the NAPLS project by Perkins, Diana O, Jeffries, Clark D, Addington, Jean, Bearden, Carrie E, Cadenhead, Kristin S, Cannon, Tyrone D, Cornblatt, Barbara A, Mathalon, Daniel H, McGlashan, Thomas H, Seidman, Larry J, Tsuang, Ming T, Walker, Elaine F, Woods, Scott W, Heinssen, Robert

“…A barrier to preventative treatments for psychosis is the absence of accurate identification of persons at highest risk. A blood test that could substantially…”
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Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome by Schneider, Maude, Debbané, Martin, Bassett, Anne S., Chow, Eva W.C., Fung, Wai Lun Alan, van den Bree, Marianne B.M., Owen, Michael, Murphy, Kieran C., Niarchou, Maria, Kates, Wendy R., Antshel, Kevin M., Fremont, Wanda, McDonald-McGinn, Donna M., Gur, Raquel E., Zackai, Elaine H., Vorstman, Jacob, Duijff, Sasja N., Klaassen, Petra W.J., Swillen, Ann, Gothelf, Doron, Green, Tamar, Weizman, Abraham, Van Amelsvoort, Therese, Evers, Laurens, Boot, Erik, Shashi, Vandana, Hooper, Stephen R., Bearden, Carrie E., Jalbrzikowski, Maria, Armando, Marco, Vicari, Stefano, Murphy, Declan G., Ousley, Opal, Campbell, Linda E., Simon, Tony J., Eliez, Stephan

“…ObjectiveChromosome 22q11.2 deletion syndrome is a neurogenetic disorder associated with high rates of schizophrenia and other psychiatric conditions. The…”
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Neuronal defects in a human cellular model of 22q11.2 deletion syndrome by Khan, Themasap A., Revah, Omer, Gordon, Aaron, Yoon, Se-Jin, Krawisz, Anna K., Goold, Carleton, Sun, Yishan, Kim, Chul Hoon, Tian, Yuan, Li, Min-Yin, Schaepe, Julia M., Ikeda, Kazuya, Amin, Neal D., Sakai, Noriaki, Yazawa, Masayuki, Kushan, Leila, Nishino, Seiji, Porteus, Matthew H., Rapoport, Judith L., Bernstein, Jonathan A., O’Hara, Ruth, Bearden, Carrie E., Hallmayer, Joachim F., Huguenard, John R., Geschwind, Daniel H., Dolmetsch, Ricardo E., Paşca, Sergiu P.

“…22q11.2 deletion syndrome (22q11DS) is a highly penetrant and common genetic cause of neuropsychiatric disease. Here we generated induced pluripotent stem…”
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A Review of Default Mode Network Connectivity and Its Association With Social Cognition in Adolescents With Autism Spectrum Disorder and Early-Onset Psychosis by Nair, Aarti, Jolliffe, Morgan, Lograsso, Yong Seuk S., Bearden, Carrie E.

“…Recent studies have demonstrated substantial phenotypic overlap, notably social impairment, between autism spectrum disorder (ASD) and schizophrenia. However,…”
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Polygenic Risk Score Contribution to Psychosis Prediction in a Target Population of Persons at Clinical High Risk by Perkins, Diana O, Olde Loohuis, Loes, Barbee, Jenna, Ford, John, Jeffries, Clark D, Addington, Jean, Bearden, Carrie E, Cadenhead, Kristin S, Cannon, Tyrone D, Cornblatt, Barbara A, Mathalon, Daniel H, McGlashan, Thomas H, Seidman, Larry J, Tsuang, Ming, Walker, Elaine F, Woods, Scott W

“…Objective:The 2-year risk of psychosis in persons who meet research criteria for a high-risk syndrome is about 15%−25%; improvements in risk prediction…”
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Association of Thalamic Dysconnectivity and Conversion to Psychosis in Youth and Young Adults at Elevated Clinical Risk by Anticevic, Alan, Haut, Kristen, Murray, John D, Repovs, Grega, Yang, Genevieve J, Diehl, Caroline, McEwen, Sarah C, Bearden, Carrie E, Addington, Jean, Goodyear, Bradley, Cadenhead, Kristin S, Mirzakhanian, Heline, Cornblatt, Barbara A, Olvet, Doreen, Mathalon, Daniel H, McGlashan, Thomas H, Perkins, Diana O, Belger, Aysenil, Seidman, Larry J, Tsuang, Ming T, van Erp, Theo G M, Walker, Elaine F, Hamann, Stephan, Woods, Scott W, Qiu, Maolin, Cannon, Tyrone D

“…Severe neuropsychiatric conditions, such as schizophrenia, affect distributed neural computations. One candidate system profoundly altered in chronic…”
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Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization by Cao, Hengyi, Chén, Oliver Y., Chung, Yoonho, Forsyth, Jennifer K., McEwen, Sarah C., Gee, Dylan G., Bearden, Carrie E., Addington, Jean, Goodyear, Bradley, Cadenhead, Kristin S., Mirzakhanian, Heline, Cornblatt, Barbara A., Carrión, Ricardo E., Mathalon, Daniel H., McGlashan, Thomas H., Perkins, Diana O., Belger, Aysenil, Seidman, Larry J., Thermenos, Heidi, Tsuang, Ming T., van Erp, Theo G. M., Walker, Elaine F., Hamann, Stephan, Anticevic, Alan, Woods, Scott W., Cannon, Tyrone D.

“…Understanding the fundamental alterations in brain functioning that lead to psychotic disorders remains a major challenge in clinical neuroscience. In…”
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A framework for the investigation of rare genetic disorders in neuropsychiatry by Sanders, Stephan J., Sahin, Mustafa, Hostyk, Joseph, Thurm, Audrey, Jacquemont, Sebastien, Avillach, Paul, Douard, Elise, Martin, Christa L., Modi, Meera E., Moreno-De-Luca, Andres, Raznahan, Armin, Anticevic, Alan, Dolmetsch, Ricardo, Feng, Guoping, Geschwind, Daniel H., Glahn, David C., Goldstein, David B., Ledbetter, David H., Mulle, Jennifer G., Pasca, Sergiu P., Samaco, Rodney, Sebat, Jonathan, Pariser, Anne, Lehner, Thomas, Gur, Raquel E., Bearden, Carrie E.

“…De novo and inherited rare genetic disorders (RGDs) are a major cause of human morbidity, frequently involving neuropsychiatric symptoms. Recent advances in…”
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Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant–Mediated Risk for Neuropsychiatric Disorders by Forsyth, Jennifer K, Nachun, Daniel, Gandal, Michael J, Geschwind, Daniel H, Anderson, Ariana E, Coppola, Giovanni, Bearden, Carrie E

“…AbstractBackground22q11.2 copy number variants are among the most highly penetrant genetic risk variants for developmental neuropsychiatric disorders such as…”
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Reciprocal Copy Number Variations at 22q11.2 Produce Distinct and Convergent Neurobehavioral Impairments Relevant for Schizophrenia and Autism Spectrum Disorder by Lin, Amy, Vajdi, Ariana, Kushan-Wells, Leila, Helleman, Gerhard, Hansen, Laura Pacheco, Jonas, Rachel K., Jalbrzikowski, Maria, Kingsbury, Lyle, Raznahan, Armin, Bearden, Carrie E.

“…22q11.2 deletions and duplications are copy number variations (CNVs) that predispose to developmental neuropsychiatric disorders. Both CNVs are associated with…”
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Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth by Hernandez, Leanna M, Kim, Minsoo, Zhang, Pan, Bethlehem, Richard A I, Hoftman, Gil, Loughnan, Robert, Smith, Diana, Bookheimer, Susan Y, Fan, Chun Chieh, Bearden, Carrie E, Thompson, Wesley K, Gandal, Michael J

“…Increased expression of the complement component 4A (C4A) gene is associated with a greater lifetime risk of schizophrenia. In the brain, C4A is involved in…”
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White Matter Integrity and Prediction of Social and Role Functioning in Subjects at Ultra-High Risk for Psychosis by Karlsgodt, Katherine H, Niendam, Tara A, Bearden, Carrie E, Cannon, Tyrone D

“…Background White matter microstructural disruptions have been observed in patients with schizophrenia. However, whether changes exist prior to disease onset or…”
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Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings by Cheon, Eun‐Jin, Bearden, Carrie E., Sun, Daqiang, Ching, Christopher R. K., Andreassen, Ole A., Schmaal, Lianne, Veltman, Dick J., Thomopoulos, Sophia I., Kochunov, Peter, Jahanshad, Neda, Thompson, Paul M., Turner, Jessica A., van Erp, Theo G.M.

“…This review compares the main brain abnormalities in schizophrenia (SZ), bipolar disorder (BD), major depressive disorder (MDD), and 22q11.2 Deletion Syndrome…”
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Social Cognition in Schizophrenia, Part 1: Performance Across Phase of Illness by GREEN, Michael F, BEARDEN, Carrie E, SUBOTNIK, Kenneth L, SUGAR, Catherine A, VENTURA, Joseph, YEE, Cindy M, NUECHTERLEIN, Keith H, CANNON, Tyrone D, FISKE, Alan P, HELLEMANN, Gerhard S, HORAN, William P, KEE, Kimmy, KERN, Robert S, LEE, Junghee, SERGI, Mark J

“…Social cognitive impairments are consistently reported in schizophrenia and are associated with functional outcome. We currently know very little about whether…”
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Multisite reliability of MR-based functional connectivity by Noble, Stephanie, Scheinost, Dustin, Finn, Emily S., Shen, Xilin, Papademetris, Xenophon, McEwen, Sarah C., Bearden, Carrie E., Addington, Jean, Goodyear, Bradley, Cadenhead, Kristin S., Mirzakhanian, Heline, Cornblatt, Barbara A., Olvet, Doreen M., Mathalon, Daniel H., McGlashan, Thomas H., Perkins, Diana O., Belger, Aysenil, Seidman, Larry J., Thermenos, Heidi, Tsuang, Ming T., van Erp, Theo G.M., Walker, Elaine F., Hamann, Stephan, Woods, Scott W., Cannon, Tyrone D., Constable, R. Todd

“…Recent years have witnessed an increasing number of multisite MRI functional connectivity (fcMRI) studies. While multisite studies provide an efficient way to…”
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Rare Genome-Wide Copy Number Variation and Expression of Schizophrenia in 22q11.2 Deletion Syndrome by Bassett, Anne S, Lowther, Chelsea, Merico, Daniele, Costain, Gregory, Chow, Eva W. C, van Amelsvoort, Therese, McDonald-McGinn, Donna, Gur, Raquel E, Swillen, Ann, Van den Bree, Marianne, Murphy, Clodagh, Murphy, Kieran, Gothelf, Doron, Bearden, Carrie E, Eliez, Stephan, Kates, Wendy, Philip, Nicole, Sashi, Vandana, Campbell, Linda, Vorstman, Jacob, Cubells, Joseph, Repetto, Gabriela M, Simon, Tony, Boot, Erik, Heung, Tracy, Evers, Rens, Vingerhoets, Claudia, van Duin, Esther, Zackai, Elaine, Vergaelen, Elfi, Devriendt, Koen, Vermeesch, Joris R, Owen, Michael, Michaelovosky, Elena, Kushan, Leila, Schneider, Maude, Fremont, Wanda, Busa, Tiffany, Hooper, Stephen, McCabe, Kathryn, Duijff, Sasja, Isaev, Karin, Pellecchia, Giovanna, Wei, John, Gazzellone, Matthew J, Scherer, Stephen W, Emanuel, Beverly S, Guo, Tingwei, Morrow, Bernice E, Marshall, Christian R

“…Objective:Chromosome 22q11.2 deletion syndrome (22q11.2DS) is associated with a more than 20-fold increased risk for developing schizophrenia. The aim of this…”
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Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study by Villalón-Reina, Julio E., Martínez, Kenia, Qu, Xiaoping, Ching, Christopher R. K., Nir, Talia M., Kothapalli, Deydeep, Corbin, Conor, Sun, Daqiang, Lin, Amy, Forsyth, Jennifer K., Kushan, Leila, Vajdi, Ariana, Jalbrzikowski, Maria, Hansen, Laura, Jonas, Rachel K., van Amelsvoort, Therese, Bakker, Geor, Kates, Wendy R., Antshel, Kevin M., Fremont, Wanda, Campbell, Linda E., McCabe, Kathryn L., Daly, Eileen, Gudbrandsen, Maria, Murphy, Clodagh M., Murphy, Declan, Craig, Michael, Emanuel, Beverly, McDonald-McGinn, Donna M., Vorstman, Jacob A.S., Fiksinski, Ania M., Koops, Sanne, Ruparel, Kosha, Roalf, David, Gur, Raquel E., Eric Schmitt, J., Simon, Tony J., Goodrich-Hunsaker, Naomi J., Durdle, Courtney A., Doherty, Joanne L., Cunningham, Adam C., van den Bree, Marianne, Linden, David E. J., Owen, Michael, Moss, Hayley, Kelly, Sinead, Donohoe, Gary, Murphy, Kieran C., Arango, Celso, Jahanshad, Neda, Thompson, Paul M., Bearden, Carrie E.

“…22q11.2 deletion syndrome (22q11DS)—a neurodevelopmental condition caused by a hemizygous deletion on chromosome 22—is associated with an elevated risk of…”
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Accelerated cortical thinning precedes and predicts conversion to psychosis: The NAPLS3 longitudinal study of youth at clinical high-risk by Collins, Meghan A., Ji, Jie Lisa, Chung, Yoonho, Lympus, Cole A., Afriyie-Agyemang, Yvette, Addington, Jean M., Goodyear, Bradley G., Bearden, Carrie E., Cadenhead, Kristin S., Mirzakhanian, Heline, Tsuang, Ming T., Cornblatt, Barbara A., Carrión, Ricardo E., Keshavan, Matcheri, Stone, Wiliam S., Mathalon, Daniel H., Perkins, Diana O., Walker, Elaine F., Woods, Scott W., Powers, Albert R., Anticevic, Alan, Cannon, Tyrone D.

“…Progressive grey matter loss has been demonstrated among clinical high-risk (CHR) individuals who convert to psychosis, but it is unknown whether these changes…”
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Association Between P300 Responses to Auditory Oddball Stimuli and Clinical Outcomes in the Psychosis Risk Syndrome by Hamilton, Holly K, Roach, Brian J, Bachman, Peter M, Belger, Aysenil, Carrion, Ricardo E, Duncan, Erica, Johannesen, Jason K, Light, Gregory A, Niznikiewicz, Margaret A, Addington, Jean, Bearden, Carrie E, Cadenhead, Kristin S, Cornblatt, Barbara A, McGlashan, Thomas H, Perkins, Diana O, Seidman, Larry J, Tsuang, Ming T, Walker, Elaine F, Woods, Scott W, Cannon, Tyrone D, Mathalon, Daniel H

“…In most patients, a prodromal period precedes the onset of schizophrenia. Although clinical criteria for identifying the psychosis risk syndrome (PRS) show…”
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