Search Results - "BEAN, Yukie"

Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer by Winham, Stacey J, Pirie, Ailith, Chen, Yian Ann, Larson, Melissa C, Fogarty, Zachary C, Earp, Madalene A, Anton-Culver, Hoda, Bandera, Elisa V, Cramer, Daniel, Doherty, Jennifer A, Goodman, Marc T, Gronwald, Jacek, Karlan, Beth Y, Kjaer, Susanne K, Levine, Douglas A, Menon, Usha, Ness, Roberta B, Pearce, Celeste L, Pejovic, Tanja, Rossing, Mary Anne, Wentzensen, Nicolas, Bean, Yukie T, Bisogna, Maria, Brinton, Louise A, Carney, Michael E, Cunningham, Julie M, Cybulski, Cezary, deFazio, Anna, Dicks, Ed M, Edwards, Robert P, Gayther, Simon A, Gentry-Maharaj, Aleksandra, Gore, Martin, Iversen, Edwin S, Jensen, Allan, Johnatty, Sharon E, Lester, Jenny, Lin, Hui-Yi, Lissowska, Jolanta, Lubinski, Jan, Menkiszak, Janusz, Modugno, Francesmary, Moysich, Kirsten B, Orlow, Irene, Pike, Malcolm C, Ramus, Susan J, Song, Honglin, Terry, Kathryn L, Thompson, Pamela J, Tyrer, Jonathan P, van den Berg, David J, Vierkant, Robert A, Vitonis, Allison F, Walsh, Christine, Wilkens, Lynne R, Wu, Anna H, Yang, Hannah, Ziogas, Argyrios, Berchuck, Andrew, Chenevix-Trench, Georgia, Schildkraut, Joellen M, Permuth-Wey, Jennifer, Phelan, Catherine M, Pharoah, Paul D P, Fridley, Brooke L, Sellers, Thomas A, Goode, Ellen L

“…While numerous susceptibility loci for epithelial ovarian cancer (EOC) have been identified, few associations have been reported with overall survival. In the…”
Get full text

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk by Lin, Hui-Yi, Tyrer, Jonathan P., Lawrenson, Kate, Dennis, Joe, Anton-Culver, Hoda, Bean, Yukie T., Bisogna, Maria, Brinton, Louise A., Brooks-Wilson, Angela, Carty, Karen, Chen, Zhihua, Chen, Y. Ann, Cook, Linda S., Cramer, Daniel W., Cunningham, Julie M., Dansonka-Mieszkowska, Agnieszka, du Bois, Andreas, Despierre, Evelyn, Doherty, Jennifer A., Dörk, Thilo, Easton, Douglas F., Eccles, Diana M., Fasching, Peter A., Fridley, Brooke L., Gao, Yu-Tang, Gentry-Maharaj, Aleksandra, Giles, Graham G., Glasspool, Rosalind, Gronwald, Jacek, Harter, Philipp, Hasmad, Hanis N., Hein, Alexander, Heitz, Florian, Hildebrandt, Michelle A. T., Hogdall, Claus K., Hogdall, Estrid, Iversen, Edwin S., Jakubowska, Anna, Ji, Bu-Tian, Karlan, Beth Y., Jim, Heather, Kiemeney, Lambertus A., Kjaer, Susanne K., Le, Nhu D., Lee, Alice W., Lester, Jenny, Levine, Douglas A., Liang, Dong, Lim, Boon Kiong, Lissowska, Jolanta, Lubinski, Jan, Lundvall, Lene, Matsuo, Keitaro, McGuire, Valerie, Menon, Usha, Milne, Roger L., Modugno, Francesmary, Moysich, Kirsten B., Nevanlinna, Heli, Eilber, Ursula, Olson, Sara H., Orlow, Irene, Orsulic, Sandra, Pearce, Celeste L., Pejovic, Tanja, Permuth-Wey, Jennifer, Pike, Malcolm C., Poole, Elizabeth M., Risch, Harvey A., Rosen, Barry, Rudolph, Anja, Runnebaum, Ingo B., Rzepecka, Iwona K., Salvesen, Helga B., Schwaab, Ira, Shu, Xiao-Ou, Shvetsov, Yurii B., Song, Honglin, Southey, Melissa C., Spiewankiewicz, Beata, Terry, Kathryn L., Thompson, Pamela J., Tangen, Ingvild L., Tworoger, Shelley S., Vergote, Ignace, Wang-Gohrke, Shan, Wicklund, Kristine G., Wu, Anna H., Wu, Xifeng, Woo, Yin-Ling, Yang, Hannah, Zheng, Wei, Ziogas, Argyrios, Kelemen, Linda E., Berchuck, Andrew, Monteiro, Alvaro N. A., Gayther, Simon A., Narod, Steven A., Pharoah, Paul D. P., Sellers, Thomas A.

“…ABSTRACT Epithelial‐mesenchymal transition (EMT) is a process whereby epithelial cells assume mesenchymal characteristics to facilitate cancer metastasis…”
Get full text

Matrix-free 3D culture supports human follicular development from the unilaminar to the antral stage in vitro yielding morphologically normal metaphase II oocytes by Xu, Fuhua, Lawson, Maralee S, Bean, Yukie, Ting, Alison Y, Pejovic, Tanja, De Geest, Koen, Moffitt, Melissa, Mitalipov, Shoukhrat M, Xu, Jing

“…Can group culture with stage-specific anti-Müllerian hormone (AMH) modulation support human follicular development and oocyte maturation in vitro? In the…”
Get full text

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer by Riggan, Marjorie J, Beesley, Jonathan, Soucy, Penny, Aalfs, Cora M, Adams, Marcia, Arnold, Norbert, Arun, Banu K, Bean, Yukie, Bermisheva, Marina, Birrer, Michael J, Blankstein, Kenneth, Bonanni, Bernardo, Bradbury, Angela R, Broberg, Per, Campbell, Ian, Cannioto, Rikki, Cescon, Terence, Chan, Salina B, Chanock, Stephen, Claes, Kathleen B M, Conner, Thomas, Dansonka-Mieszkowska, Agnieszka, Davidson, Rosemarie, Dürst, Matthias, Ellis, Steve, Fasching, Peter A, Ferguson, Sarah, Frost, Debra, Gentry-Maharaj, Aleksandra, Gore, Martin, Gronwald, Jacek, Gruber, Stephen, Håkansson, Niclas, Hauke, Jan, Hildebrandt, Michelle A T, Høgdall, Claus K, Hogervorst, Frans B L, Hulick, Peter J, Imyanitov, Evgeny N, Izatt, Louise, Izquierdo, Angel, Jensen, Allan, Karnezis, Anthony, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lee, Jong Won, Lele, Shashikant B, Leroux, Dominique, Lesueur, Fabienne, Lilyquist, Jenna, Mai, Phuong L, McAlpine, Jessica N, McGuire, Valerie, Mensenkamp, Arjen R, Modugno, Francesmary, Moes-Sosnowska, Joanna, Mulligan, Anna Marie, Musinsky, Jacob, Nedergaard, Lotte, Ness, Roberta B, Nevanlinna, Heli, Niederacher, Dieter, Nussbaum, Robert L, Onland-Moret, N Charlotte, Paul, James, Pelttari, Liisa M, Pezzani, Lidia, Phillips, Kelly-Anne, Poppe, Bruce, Prieur, Fabienne, Prokofyeva, Darya, Rice, Patricia, Rodriguez, Gustavo C, Rookus, Matti A, Senter, Leigha, Shelford, Tameka, Siddiqui, Nadeem, Side, Lucy E, Stadler, Zsofia, Sutphen, Rebecca, Sutter, Christian, Szabo, Csilla I, Terry, Kathryn L, Tihomirova, Laima, Tung, Nadine, Van Heetvelde, Mattias, Varon-Mateeva, Raymonda, Walsh, Christine, Wappenschmidt, Barbara, Webb, Penelope M, Weinberg, Clarice R, Weitzel, Jeffrey N, Yang, Hannah, Goodman, Marc T, Park, Sue K, Risch, Harvey A, Offit, Kenneth, Simard, Jacques, Chenevix-Trench, Georgia, Goode, Ellen L

“…Paul Pharoah and colleagues report the results of a large genome-wide association study of ovarian cancer. They identify new susceptibility loci for different…”
Get full text

Abstract 2577: Pre-cancerous ovarian cells harboring a familial SMARCA4 mutation acquire in vitro phenotypes associated with transformation in SSCOHT by Joshi, Sonali, Campbell, Shawn, Bean, Yukie, Pejovic, Tanja, Krieg, Adam

“…Abstract Introduction: Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) is an extremely rare but deadly ovarian cancer associated with mutations…”
Get full text

Identification of six new susceptibility loci for invasive epithelial ovarian cancer by Lee, Andrew, Pejovic, Tanja, Li, Qiyuan, Hazelett, Dennis, Miron, Alexander, Southey, Melissa, Terry, Mary Beth, Buys, Saundra S, Janavicius, Ramunas, Barrowdale, Daniel, Dennis, Joe, Papi, Laura, Konstantopoulou, Irene, Frost, Debra, Platte, Radka, Ellis, Steve, Sinilnikova, Olga M, Damiola, Francesca, Mazoyer, Sylvie, Stoppa-Lyonnet, Dominique, Piedmonte, Marion, O'Malley, David M, de la Hoya, Miguel, Aittomäki, Kristiina, Rookus, Matti A, Tihomirova, Laima, Hamann, Ute, Imyanitov, Evgeny N, Hogervorst, Frans B L, Diez, Orland, Blanco, Ignacio, Lubinski, Jan, Sukiennicki, Grzegorz, Barkardottir, Rosa B, Plante, Marie, Montagna, Marco, Tognazzo, Silvia, Teixeira, Manuel R, Pankratz, Vernon S, Wang, Xianshu, Vijai, Joseph, Aghajanian, Carol A, Berger, Andreas, Tea, Muy-Kheng, Rennert, Gad, Glendon, Gord, Kruse, Torben A, Thomassen, Mads, Zidan, Jamal, Einbeigi, Zakaria, Nussbaum, Robert L, Lester, Jenny, Lambrechts, Diether, Lambrechts, Sandrina, Dicks, Ed, Rossing, Mary Anne, Eilber, Ursula, Wilkens, Lynne R, Hillemanns, Peter, Antonenkova, Natalia, Leminen, Arto, Modugno, Francesmary, Ness, Roberta B, Matsuo, Keitaro, Hosono, Satoyo, Kjaer, Susanne Kruger, Hogdall, Estrid, Woo, Yin-Ling, Goode, Ellen L, Berchuck, Andrew, Iversen, Edwin S, Cramer, Daniel W, Terry, Kathryn L, Bandera, Elisa V, Orlow, Irene, Tangen, Ingvild L, Aben, Katja K H, Brooks-Wilson, Angela, Cybulski, Cezary, Lundvall, Lene, Baker, Helen, Eccles, Diana, Paul, James, Carty, Karen, McGuire, Valerie, Zheng, Wei, Gao, Yu-Tang, Rosen, Barry, Risch, Harvey A, Narod, Steven A, Monteiro, Alvaro N, Lin, Hui-Yi, Tsai, Ya-Yu, Ziogas, Argyrios, Anton-Culver, Hoda, Gentry-Maharaj, Aleksandra, Menon, Usha, Dansonka-Mieszkowska, Agnieszka, Easton, Douglas F, Chenevix-Trench, Georgia

“…Georgia Chenevix-Trench and colleagues report meta-analyses of genome-wide association studies identifying six loci newly associated with epithelial ovarian…”
Get full text

14 In vitro transformation of ovarian surface epithelium links a mutation in SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 4 to familial small carcinoma of the ovary hypercalcemic type by Krieg, Adam, Joshi, Sonali, Campbell, Shawn, Bean, Yukie T., Pejovic, Tanja

“…Using a unique population of cells derived from a familial carrier of an SCCOHT-associated SMARCA4 mutation (SMARCA4. c.3081+1G>T), we sought to determine if…”
Get full text

ABCA transporter gene expression and poor outcome in epithelial ovarian cancer by Hedditch, Ellen L, Gao, Bo, Russell, Amanda J, Lu, Yi, Emmanuel, Catherine, Beesley, Jonathan, Johnatty, Sharon E, Chen, Xiaoqing, Harnett, Paul, George, Joshy, Williams, Rebekka T, Flemming, Claudia, Lambrechts, Diether, Despierre, Evelyn, Lambrechts, Sandrina, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter, Beckmann, Matthias W, Ekici, Arif B, Hein, Alexander, Matsuo, Keitaro, Hosono, Satoyo, Nakanishi, Toru, Yatabe, Yasushi, Pejovic, Tanja, Bean, Yukie, Heitz, Florian, Harter, Philipp, du Bois, Andreas, Schwaab, Ira, Hogdall, Estrid, Kjaer, Susan K, Jensen, Allan, Hogdall, Claus, Lundvall, Lene, Engelholm, Svend Aage, Brown, Bob, Flanagan, James, Metcalf, Michelle D, Siddiqui, Nadeem, Sellers, Thomas, Fridley, Brooke, Cunningham, Julie, Schildkraut, Joellen, Iversen, Ed, Weber, Rachel P, Berchuck, Andrew, Goode, Ellen, Bowtell, David D, Chenevix-Trench, Georgia, deFazio, Anna, Norris, Murray D, MacGregor, Stuart, Haber, Michelle, Henderson, Michelle J

“…ATP-binding cassette (ABC) transporters play various roles in cancer biology and drug resistance, but their association with outcomes in serous epithelial…”
Get full text

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma by Joshi, Sonali, Campbell, Shawn, Lim, Jeong Y, McWeeney, Shannon, Krieg, Adam, Bean, Yukie, Pejovic, Nadja, Mhawech-Fauceglia, Paulette, Pejovic, Tanja

“…Ovarian cancer is a leading cause of death from gynecological cancers. Late diagnosis and resistance to therapy results in mortality and effective screening is…”
Get full text

Estradiol does not modulate FANCD2 in high risk ovarian surface epithelial cells by Kellar, Melissa, Wright, Jay, Engel, Sharon, Bean, Yukie, Pejovic, Tanja

Get full text

Abstract POSTER-BIOL-1308: Macrophage infiltration in high-grade serous carcinomas of humans and mice by Pejovic, Tanja, Bean, Yukie, Kim, Jaeyeon, Matzuk, Martin M., Coffelt, Seth B.

“…Abstract Over the past 10-15 years, focus on the immune system has reinvigorated cancer research and oncology. Both clinical and experimental evidence…”
Get full text

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer by Lawrenson, Kate, Li, Qiyuan, Kar, Siddhartha, Seo, Ji-Heui, Chen, Yibu, Karst, Alison, Drapkin, Ronny, Aben, Katja K. H., Anton-Culver, Hoda, Antonenkova, Natalia, Baker, Helen, Bean, Yukie, Berchuck, Andrew, Bjorge, Line, Bogdanova, Natalia, Brinton, Louise A., Brooks-Wilson, Angela, Bruinsma, Fiona, Campbell, Ian G., Carty, Karen, Chen, Zhihua, Cybulski, Cezary, Dicks, Ed, Doherty, Jennifer A., du Bois, Andreas, Eccles, Diana, Easton, Douglas T., Edwards, Robert P., Fasching, Peter A., Fridley, Brooke L., Gao, Yu-Tang, Gentry-Maharaj, Aleksandra, Giles, Graham G., Glasspool, Rosalind, Goodman, Marc T., Grownwald, Jacek, Harrington, Patricia, Harter, Philipp, Hasmad, Hanis Nazihah, Hein, Alexander, Hildebrandt, Michelle A. T., Hillemanns, Peter, Hosono, Satoyo, Iversen, Edwin S., Jakubowska, Anna, James, Paul, Ji, Bu-Tian, Karlan, Beth Y., Kruger Kjaer, Susanne, Kelemen, Linda E., Kellar, Melissa, Kelley, Joseph L., Kiemeney, Lambertus A., Lambrechts, Diether, Lele, Shashi, Leminen, Arto, Levine, Douglas A., Liang, Dong, Lubinski, Jan, Lundvall, Lene, Massuger, Leon F. A. G., Matsuo, Keitaro, McLaughlin, John R., Nevanlinna, Heli, McNeish, Ian, Menon, Usha, Modugno, Francesmary, Nedergaard, Lotte, Olson, Sara H., Orlow, Irene, Weber, Rachel Palmieri, Pearce, Celeste L., Permuth-Wey, Jennifer, Poole, Elizabeth M., Risch, Harvey A., Rosen, Barry, Rudolph, Anja, Salvesen, Helga B., Schildkraut, Joellen M., Schwaab, Ira, Shu, Xiao-Ou, Shvetsov, Yurii B., Siddiqui, Nadeem, Song, Honglin, Southey, Melissa C., Teo, Soo-Hwang, Terry, Kathryn L., Thompson, Pamela J., Timorek, Agnieszka, van Altena, Anne M., Van Nieuwenhuysen, Els, Vierkant, Robert A., Whittemore, Alice S., Wicklund, Kristine G., Wilkens, Lynne R., Wu, Xifeng, Yang, Hannah, Zheng, Wei, Monteiro, Alvaro, Gayther, Simon A.

“…Genome-wide association studies have reported 11 regions conferring risk of high-grade serous epithelial ovarian cancer (HGSOC). Expression quantitative trait…”
Get full text

Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci by Coetzee, Simon G, Shen, Howard C, Hazelett, Dennis J, Lawrenson, Kate, Kuchenbaecker, Karoline, Tyrer, Jonathan, Rhie, Suhn K, Levanon, Keren, Karst, Alison, Drapkin, Ronny, Ramus, Susan J, Couch, Fergus J, Offit, Kenneth, Chenevix-Trench, Georgia, Monteiro, Alvaro N A, Antoniou, Antonis, Freedman, Matthew, Coetzee, Gerhard A, Pharoah, Paul D P, Noushmehr, Houtan, Gayther, Simon A

“…Understanding the regulatory landscape of the human genome is a central question in complex trait genetics. Most single-nucleotide polymorphisms (SNPs)…”
Get full text

ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas by Johnatty, Sharon E, Beesley, Jonathan, Gao, Bo, Chen, Xiaoqing, Lu, Yi, Law, Matthew H, Henderson, Michelle J, Russell, Amanda J, Hedditch, Ellen L, Emmanuel, Catherine, Fereday, Sian, Webb, Penelope M, Goode, Ellen L, Vierkant, Robert A, Fridley, Brooke L, Cunningham, Julie M, Fasching, Peter A, Beckmann, Matthias W, Ekici, Arif B, Hogdall, Estrid, Kjaer, Susanne K, Jensen, Allan, Hogdall, Claus, Brown, Robert, Paul, Jim, Lambrechts, Sandrina, Despierre, Evelyn, Vergote, Ignace, Lester, Jenny, Karlan, Beth Y, Heitz, Florian, du Bois, Andreas, Harter, Philipp, Schwaab, Ira, Bean, Yukie, Pejovic, Tanja, Levine, Douglas A, Goodman, Marc T, Camey, Michael E, Thompson, Pamela J, Lurie, Galina, Shildkraut, Joellen, Berchuck, Andrew, Terry, Kathryn L, Cramer, Daniel W, Norris, Murray D, Haber, Michelle, MacGregor, Stuart, deFazio, Anna, Chenevix-Trench, Georgia

“…Abstract Objective ABCB1 encodes the multi-drug efflux pump P-glycoprotein (P-gp) and has been implicated in multi-drug resistance. We comprehensively…”
Get full text

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk by Kar, Siddhartha P, Tyrer, Jonathan P, Li, Qiyuan, Lawrenson, Kate, Aben, Katja K H, Anton-Culver, Hoda, Antonenkova, Natalia, Chenevix-Trench, Georgia, Baker, Helen, Bandera, Elisa V, Bean, Yukie T, Beckmann, Matthias W, Berchuck, Andrew, Bisogna, Maria, Bjørge, Line, Bogdanova, Natalia, Brinton, Louise, Brooks-Wilson, Angela, Butzow, Ralf, Campbell, Ian, Carty, Karen, Chang-Claude, Jenny, Chen, Yian Ann, Chen, Zhihua, Cook, Linda S, Cramer, Daniel, Cunningham, Julie M, Cybulski, Cezary, Dansonka-Mieszkowska, Agnieszka, Dennis, Joe, Dicks, Ed, Doherty, Jennifer A, Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Eccles, Diana, Easton, Douglas F, Edwards, Robert P, Ekici, Arif B, Fasching, Peter A, Fridley, Brooke L, Gao, Yu-Tang, Gentry-Maharaj, Aleksandra, Giles, Graham G, Glasspool, Rosalind, Goode, Ellen L, Goodman, Marc T, Grownwald, Jacek, Harrington, Patricia, Harter, Philipp, Hein, Alexander, Heitz, Florian, Hildebrandt, Michelle A T, Hillemanns, Peter, Hogdall, Estrid, Hogdall, Claus K, Hosono, Satoyo, Iversen, Edwin S, Jakubowska, Anna, Paul, James, Jensen, Allan, Ji, Bu-Tian, Karlan, Beth Y, Kjaer, Susanne K, Kelemen, Linda E, Kellar, Melissa, Kelley, Joseph, Kiemeney, Lambertus A, Krakstad, Camilla, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Le, Nhu D, Lee, Alice W, Lele, Shashi, Leminen, Arto, Lester, Jenny, Levine, Douglas A, Liang, Dong, Lissowska, Jolanta, Lu, Karen, Lubinski, Jan, Lundvall, Lene, Massuger, Leon, Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R, McNeish, Iain A, Menon, Usha, Modugno, Francesmary, Moysich, Kirsten B, Narod, Steven A, Nedergaard, Lotte, Ness, Roberta B, Nevanlinna, Heli, Odunsi, Kunle, Olson, Sara H, Orlow, Irene, Orsulic, Sandra, Weber, Rachel Palmieri

“…Genome-wide association studies (GWAS) have so far reported 12 loci associated with serous epithelial ovarian cancer (EOC) risk. We hypothesized that some of…”
Get full text

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility by Earp, Madalene, Tyrer, Jonathan P, Winham, Stacey J, Lin, Hui-Yi, Chornokur, Ganna, Dennis, Joe, Aben, Katja K H, Anton-Culver, Hoda, Antonenkova, Natalia, Bandera, Elisa V, Bean, Yukie T, Beckmann, Matthias W, Bjorge, Line, Bogdanova, Natalia, Brinton, Louise A, Brooks-Wilson, Angela, Bruinsma, Fiona, Bunker, Clareann H, Butzow, Ralf, Campbell, Ian G, Carty, Karen, Chang-Claude, Jenny, Cook, Linda S, Cramer, Daniel W, Cunningham, Julie M, Cybulski, Cezary, Dansonka-Mieszkowska, Agnieszka, Despierre, Evelyn, Doherty, Jennifer A, Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Easton, Douglas F, Eccles, Diana M, Edwards, Robert P, Ekici, Arif B, Fasching, Peter A, Fridley, Brooke L, Gentry-Maharaj, Aleksandra, Giles, Graham G, Glasspool, Rosalind, Goodman, Marc T, Gronwald, Jacek, Harter, Philipp, Hein, Alexander, Heitz, Florian, Hildebrandt, Michelle A T, Hillemanns, Peter, Hogdall, Claus K, Høgdall, Estrid, Hosono, Satoyo, Iversen, Edwin S, Jakubowska, Anna, Jensen, Allan, Ji, Bu-Tian, Jung, Audrey Y, Karlan, Beth Y, Kellar, Melissa, Kiemeney, Lambertus A, Kiong Lim, Boon, Kjaer, Susanne K, Krakstad, Camilla, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Le, Nhu D, Lele, Shashi, Lester, Jenny, Levine, Douglas A, Li, Zheng, Liang, Dong, Lissowska, Jolanta, Lu, Karen, Lubinski, Jan, Lundvall, Lene, Massuger, Leon F A G, Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R, McNeish, Iain, Menon, Usha, Milne, Roger L, Modugno, Francesmary, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Odunsi, Kunle, Olson, Sara H, Orlow, Irene, Orsulic, Sandra, Paul, James, Pejovic, Tanja, Pelttari, Liisa M, Permuth, Jenny B, Pike, Malcolm C, Poole, Elizabeth M, Rosen, Barry, Rossing, Mary Anne, Rothstein, Joseph H, Runnebaum, Ingo B

“…Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer mortality in American women. Normal ovarian physiology is intricately connected to small…”
Get full text

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk by Chornokur, Ganna, Lin, Hui-Yi, Tyrer, Jonathan P, Lawrenson, Kate, Dennis, Joe, Amankwah, Ernest K, Qu, Xiaotao, Tsai, Ya-Yu, Jim, Heather S L, Chen, Zhihua, Chen, Ann Y, Permuth-Wey, Jennifer, Aben, Katja K H, Anton-Culver, Hoda, Antonenkova, Natalia, Bruinsma, Fiona, Bandera, Elisa V, Bean, Yukie T, Beckmann, Matthias W, Bisogna, Maria, Bjorge, Line, Bogdanova, Natalia, Brinton, Louise A, Brooks-Wilson, Angela, Bunker, Clareann H, Butzow, Ralf, Campbell, Ian G, Carty, Karen, Chang-Claude, Jenny, Cook, Linda S, Cramer, Daniel W, Cunningham, Julie M, Cybulski, Cezary, Dansonka-Mieszkowska, Agnieszka, du Bois, Andreas, Despierre, Evelyn, Dicks, Ed, Doherty, Jennifer A, Dörk, Thilo, Dürst, Matthias, Easton, Douglas F, Eccles, Diana M, Edwards, Robert P, Ekici, Arif B, Fasching, Peter A, Fridley, Brooke L, Gao, Yu-Tang, Gentry-Maharaj, Aleksandra, Giles, Graham G, Glasspool, Rosalind, Goodman, Marc T, Gronwald, Jacek, Harrington, Patricia, Harter, Philipp, Hein, Alexander, Heitz, Florian, Hildebrandt, Michelle A T, Hillemanns, Peter, Hogdall, Claus K, Hogdall, Estrid, Hosono, Satoyo, Jakubowska, Anna, Jensen, Allan, Ji, Bu-Tian, Karlan, Beth Y, Kelemen, Linda E, Kellar, Mellissa, Kiemeney, Lambertus A, Krakstad, Camilla, Kjaer, Susanne K, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Le, Nhu D, Lee, Alice W, Lele, Shashi, Leminen, Arto, Lester, Jenny, Levine, Douglas A, Liang, Dong, Lim, Boon Kiong, Lissowska, Jolanta, Lu, Karen, Lubinski, Jan, Lundvall, Lene, Massuger, Leon F A G, Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R, McNeish, Iain, Menon, Usha, Milne, Roger L, Modugno, Francesmary, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Eilber, Ursula, Odunsi, Kunle, Olson, Sara H, Orlow, Irene

“…Defective cellular transport processes can lead to aberrant accumulation of trace elements, iron, small molecules and hormones in the cell, which in turn may…”
Get full text

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology by Kelemen, Linda E, Earp, Madalene, Fridley, Brooke L, Chenevix-Trench, Georgia, Fasching, Peter A, Beckmann, Matthias W, Ekici, Arif B, Hein, Alexander, Lambrechts, Diether, Lambrechts, Sandrina, Van Nieuwenhuysen, Els, Vergote, Ignace, Rossing, Mary Anne, Doherty, Jennifer A, Chang-Claude, Jenny, Behrens, Sabine, Moysich, Kirsten B, Cannioto, Rikki, Lele, Shashikant, Odunsi, Kunle, Goodman, Marc T, Shvetsov, Yurii B, Thompson, Pamela J, Wilkens, Lynne R, Dörk, Thilo, Antonenkova, Natalia, Bogdanova, Natalia, Hillemanns, Peter, Runnebaum, Ingo B, du Bois, Andreas, Harter, Philipp, Heitz, Florian, Schwaab, Ira, Butzow, Ralf, Pelttari, Liisa M, Nevanlinna, Heli, Modugno, Francesmary, Edwards, Robert P, Kelley, Joseph L, Ness, Roberta B, Karlan, Beth Y, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Kjaer, Susanne K, Jensen, Allan, Cunningham, Julie M, Vierkant, Robert A, Giles, Graham G, Bruinsma, Fiona, Southey, Melissa C, Hildebrandt, Michelle A T, Liang, Dong, Lu, Karen, Wu, Xifeng, Sellers, Thomas A, Levine, Douglas A, Schildkraut, Joellen M, Iversen, Edwin S, Terry, Kathryn L, Cramer, Daniel W, Tworoger, Shelley S, Poole, Elizabeth M, Bandera, Elisa V, Olson, Sara H, Orlow, Irene, Vestrheim Thomsen, Liv Cecilie, Bjorge, Line, Krakstad, Camilla, Tangen, Ingvild L, Kiemeney, Lambertus A, Aben, Katja K H, Massuger, Leon F A G, van Altena, Anne M, Pejovic, Tanja, Bean, Yukie, Kellar, Melissa, Cook, Linda S, Le, Nhu D, Brooks-Wilson, Angela, Gronwald, Jacek, Cybulski, Cezary, Jakubowska, Anna, Lubiński, Jan, Wentzensen, Nicolas, Brinton, Louise A, Lissowska, Jolanta, Hogdall, Estrid, Engelholm, Svend Aage, Hogdall, Claus, Lundvall, Lene, Nedergaard, Lotte, Pharoah, Paul D P, Dicks, Ed, Song, Honglin, Tyrer, Jonathan P, McNeish, Iain, Siddiqui, Nadeem, Carty, Karen, Glasspool, Rosalind

“…Thymidylate synthase (TYMS) is a crucial enzyme for DNA synthesis. TYMS expression is regulated by its antisense mRNA, ENOSF1. Disrupted regulation may promote…”
Get full text

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer by French, Juliet D, Johnatty, Sharon E, Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J, Russell, Amanda J, Kar, Siddhartha, Chen, Xiaoqing, Hillman, Kristine M, Kaufmann, Susanne, Sivakumaran, Haran, O'Reilly, Martin, Wang, Chen, Korbie, Darren J, Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandrina, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A, Beckmann, Matthias W, Ekici, Arif B, Hein, Alexander, Matsuo, Keitaro, Hosono, Satoyo, Pisterer, Jacobus, Hillemanns, Peter, Nakanishi, Toru, Yatabe, Yasushi, Goodman, Marc T, Lurie, Galina, Matsuno, Rayna K, Thompson, Pamela J, Pejovic, Tanja, Bean, Yukie, Heitz, Florian, Harter, Philipp, du Bois, Andreas, Schwaab, Ira, Hogdall, Estrid, Kjaer, Susanne K, Jensen, Allan, Hogdall, Claus, Lundvall, Lene, Engelholm, Svend Aage, Brown, Bob, Flanagan, James M, Metcalf, Michelle D, Siddiqui, Nadeem, Sellers, Thomas, Fridley, Brooke, Cunningham, Julie, Schildkraut, Joellen M, Iversen, Ed, Weber, Rachel Palmieri, Brennan, Donal, Berchuck, Andrew, Pharoah, Paul, Harnett, Paul, Norris, Murray D, Haber, Michelle, Goode, Ellen L, Lee, Jason S, Khanna, Kum Kum, Meyer, Kerstin B, Chenevix-Trench, Georgia, deFazio, Anna, Edwards, Stacey L, MacGregor, Stuart

“…Women with epithelial ovarian cancer (EOC) are usually treated with platinum/taxane therapy after cytoreductive surgery but there is considerable…”
Get full text

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer by van der Baan, Frederieke H, Johnatty, Sharon E, Antonenkova, Natalia N, Apicella, Carmel, Baglietto, Laura, Balleine, Rosemary, Barrowdale, Daniel, Benitez, Javier, Berger, Raanan, Beuselinck, Benoit, Bisogna, Maria, Bojesen, Stig E, Brunet, Joan, Brüning, Thomas, Bunker, Clareann H, Caligo, Maria A, Cybulski, Cezary, de la Hoya, Miguel, Devilee, Peter, Diez, Orland, du Bois, Andreas, Duran, Mercedes, Easton, Douglas F, Eccles, Diana, Fasching, Peter A, Fletcher, Olivia, Friebel, Tara, Gayther, Simon A, Gentry-Maharaj, Aleksandra, Gerdes, Anne-Marie, Greene, Mark H, Grip, Mervi, Gschwantler Kaulich, Daphne, Haeberle, Lothar, Haiman, Christopher A, Hansen, Thomas V.O, Harter, Philipp, Hartikainen, Jaana M, Healey, Sue, Henderson, Brian E, Imyanitov, Evgeny N, Jensen, Allan, Karlan, Beth Y, Kjaer, Susanne K, Knight, Julia A, Knol-Bout, Jacoba P, Kosma, Veli-Matti, Lambrechts, Sandrina, Larson, Melissa C, Lasa, Adriana, Le, Nhu D, Leminen, Arto, Lester, Jenny, Li, Jingmei, Lindblom, Annika, Lissowska, Jolanta, Lu, Karen H, Lundvall, Lene, Mannermaa, Arto, McNeish, Iain, Modugno, Francesmary, Muranen, Taru A, Narod, Steven A, Nevanlinna, Heli, Pedersen, Inge Sokilde, Pike, Malcolm C, Plisiecka-Halasa, Joanna, Rebbeck, Timothy R, Reed, Malcolm W.R, Rodriguez, Gustavo C, Romero, Atocha, Rossing, Mary Anne, Rothstein, Joseph H, Rudolph, Anja, Salani, Ritu, Sawyer, Elinor J, Schmidt, Marjanka K, Schneeweiss, Andreas, Schoemaker, Minouk J, Schrauder, Michael G, Shrubsole, Martha, Sieh, Weiva, Sinilnikova, Olga M, Smeets, Dominiek, Tangen, Ingvild L, Terry, Kathryn L, Terry, Mary Beth, Thompson, Pamela J, Truong, Thérèse, Tyrer, Jonathan P, Vachon, Celine M, Van 't Veer, Laura J, van Altena, Anne M, Vitonis, Allison F, von Wachenfeldt, Anna, Walsh, Christine, Weitzel, Jeffrey N, Weltens, Caroline, Wentzensen, Nicolas, Rookus, Matti A

“…Abstract Objective Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3′ UTR microRNA binding site,…”
Get full text