Search Results - "BAZMI, Hengameh Z"

In Vitro Selection and Analysis of Human Immunodeficiency Virus Type 1 Resistant to Derivatives of β-2′,3′-Didehydro-2′,3′-Dideoxy-5-Fluorocytidine by HAMMOND, Jennifer L, PARIKH, Urvi M, KOONTZ, Dianna L, SCHLUETER-WIRTZ, Susan, CHU, Chung K, BAZMI, Hengameh Z, SCHINAZI, Raymond F, MELLORS, John W

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Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate by Tramontano, Enzo, Piras, Giovanna, Mellors, John W, Putzolu, Monica, Bazmi, Hengameh Z, Colla, Paolo La

“…Mutations at amino acid residues 161 (Q161L) and 208 (H208Y) of the reverse transcriptase (RT) have been identified in HIV-1 variants which are resistant to…”
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A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150) by Mellors, J W, Im, G J, Tramontano, E, Winkler, S R, Medina, D J, Dutschman, G E, Bazmi, H Z, Piras, G, Gonzalez, C J, Cheng, Y C

“…Tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione (TIBO) derivatives (e.g., R82150) are potent, human immunodeficiency virus-1…”
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