Search Results - "BAZE, Wallace B"
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Prolonged myelination in human neocortical evolution
Published in Proceedings of the National Academy of Sciences - PNAS (09-10-2012)“…Nerve myelination facilitates saltatory action potential conduction and exhibits spatiotemporal variation during development associated with the acquisition of…”
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2
Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents
Published in Proceedings of the National Academy of Sciences - PNAS (31-03-2020)“…Described here is the development of gadolinium(III) texaphyrin-platinum(IV) conjugates capable of overcoming platinum resistance by 1) localizing to solid…”
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3
Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex resembles humans
Published in Proceedings of the National Academy of Sciences - PNAS (18-06-2013)“…Neocortical development in humans is characterized by an extended period of synaptic proliferation that peaks in mid-childhood, with subsequent pruning through…”
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4
Functional genomic characterization of virulence factors from necrotizing fasciitis-causing strains of Aeromonas hydrophila
Published in Applied and Environmental Microbiology (01-07-2014)“…The genomes of 10 Aeromonas isolates identified and designated Aeromonas hydrophila WI, Riv3, and NF1 to NF4; A. dhakensis SSU; A. jandaei Riv2; and A. caviae…”
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5
A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys
Published in Science translational medicine (09-11-2011)“…Obesity, defined as body mass index greater than 30, is a leading cause of morbidity and mortality and a financial burden worldwide. Despite significant…”
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6
Developmental changes in the spatial organization of neurons in the neocortex of humans and common chimpanzees
Published in Journal of comparative neurology (1911) (15-12-2013)“…ABSTRACT In adult humans the prefrontal cortex possesses wider minicolumns and more neuropil space than other cortical regions. These aspects of prefrontal…”
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7
Antibacterial Role for Natural Killer Cells in Host Defense to Bacillus anthracis
Published in Infection and Immunity (01-01-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Protective Immunity Elicited by Oral Immunization of Mice with Salmonella enterica Serovar Typhimurium Braun Lipoprotein (Lpp) and Acetyltransferase (MsbB) Mutants
Published in Frontiers in cellular and infection microbiology (10-11-2016)“…We evaluated the extent of attenuation and immunogenicity of the Δ and Δ Δ mutants of serovar Typhimurium when delivered to mice by the oral route. These…”
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Braun Lipoprotein (Lpp) Contributes to Virulence of Yersiniae: Potential Role of Lpp in Inducing Bubonic and Pneumonic Plague
Published in Infection and Immunity (01-04-2008)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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10
Teixobactin Provides Protection against Inhalation Anthrax in the Rabbit Model
Published in Pathogens (Basel) (22-09-2020)“…The use of antibiotics is a vital means of treating infections caused by the bacteria Bacillus (B.) anthracis. Importantly, with the potential future use of…”
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Human Monoclonal Antibody AVP-21D9 to Protective Antigen Reduces Dissemination of the Bacillus anthracis Ames Strain from the Lungs in a Rabbit Model
Published in Infection and Immunity (01-07-2007)“…Dutch-belted and New Zealand White rabbits were passively immunized with AVP-21D9, a human monoclonal antibody to protective antigen (PA), at the time of…”
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Unraveling the mechanism of action of a new type III secretion system effector AexU from Aeromonas hydrophila
Published in Microbial pathogenesis (01-09-2010)“…We recently characterized a T3SS effector, AexU, from a diarrheal isolate SSU of Aeromonas hydrophila, which exhibited ADP-ribosyltransferase (ADPRT) activity…”
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13
Safety of chronic intrathecal morphine infusion in a sheep model
Published in Anesthesiology (Philadelphia) (01-07-2003)“…The safety of chronically administered intrathecal morphine has been questioned. Therefore, the authors examined the behavioral and neurologic effects and…”
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14
Hemodynamic effects of anthrax toxins in the rabbit model and the cardiac pathology induced by lethal toxin
Published in Toxins (01-06-2011)“…Anthrax lethal toxin (LeTx) and edema toxin (EdTx) have been shown to alter hemodynamics in the rodent model, while LeTx primarily is reported to induce…”
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15
Dendritic morphology of pyramidal neurons in the chimpanzee neocortex: regional specializations and comparison to humans
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2013)“…The primate cerebral cortex is characterized by regional variation in the structure of pyramidal neurons, with more complex dendritic arbors and greater spine…”
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Experimental Zika Virus Infection of Neotropical Primates
Published in The American journal of tropical medicine and hygiene (01-01-2018)“…The establishment of a sylvatic reservoir of Zika virus (ZIKV) in the Americas is dependent on the susceptibility of primates of sufficient population density,…”
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Preclinical Evaluation of the Short-Term Toxicity of 4-(N)-Docosahexaenoyl 2´, 2´- Difluorodeoxycytidine (DHA-dFdC)
Published in Pharmaceutical research (01-06-2017)“…Purpose This study was designed to test the short-term toxicity of DHA-dFdC in a mouse model and its efficacy in a mouse model of leukemia at or below its…”
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Targeting the interleukin‐11 receptor α in metastatic prostate cancer: A first‐in‐man study
Published in Cancer (15-07-2015)“…BACKGROUND Receptors in tumor blood vessels are attractive targets for ligand‐directed drug discovery and development. The authors have worked systematically…”
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19
Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques
Published in Retrovirology (27-04-2016)“…HIV reservoirs pose major challenges to viral eradication. The main cellular reservoirs include CD4 T cells and macrophages, whereas anatomic reservoirs are…”
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Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy
Published in Brain (London, England : 1878) (01-02-2017)“…Leukoencephalopathies are a group of white matter disorders related to abnormal formation, maintenance, and turnover of myelin in the central nervous system…”
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