Search Results - "BAXTER, Paul"

Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes by Baxter, Paul S., Hardingham, Giles E.

“…The human brain generally remains structurally and functionally sound for many decades, despite the post-mitotic and non-regenerative nature of neurons. This…”
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Robot education peers in a situated primary school study: Personalisation promotes child learning by Baxter, Paul, Ashurst, Emily, Read, Robin, Kennedy, James, Belpaeme, Tony

“…The benefit of social robots to support child learning in an educational context over an extended period of time is evaluated. Specifically, the effect of…”
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Conception and Evaluation of a Library of Cleavable Mass Tags for Digital Polymers Sequencing by Schutz, Thibault, Sergent, Isaure, Obeid, Georgette, Oswald, Laurence, Al Ouahabi, Abdelaziz, Baxter, Paul N. W., Clément, Jean‐Louis, Gigmes, Didier, Charles, Laurence, Lutz, Jean‐François

“…A library of phosphoramidite monomers containing a main‐chain cleavable alkoxyamine and a side‐chain substituent of variable molar mass (i.e. mass tag) was…”
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Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes by Baxter, Paul S., Dando, Owen, Emelianova, Katie, He, Xin, McKay, Sean, Hardingham, Giles E., Qiu, Jing

“…Microglia, brain-resident macrophages, require instruction from the CNS microenvironment to maintain their identity and morphology and regulate inflammatory…”
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The Effect of Endogenous Cushing Syndrome on All-cause and Cause-specific Mortality by Limumpornpetch, Padiporn, Morgan, Ann W, Tiganescu, Ana, Baxter, Paul D, Nyawira Nyaga, Victoria, Pujades-Rodriguez, Mar, Stewart, Paul M

“…We aimed to perform a systematic review and meta-analysis of all-cause and cause-specific mortality of patients with benign endogenous Cushing syndrome (CS)…”
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Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance by Rode, Baptiste, Shi, Jian, Endesh, Naima, Drinkhill, Mark J., Webster, Peter J., Lotteau, Sabine J., Bailey, Marc A., Yuldasheva, Nadira Y., Ludlow, Melanie J., Cubbon, Richard M., Li, Jing, Futers, T. Simon, Morley, Lara, Gaunt, Hannah J., Marszalek, Katarzyna, Viswambharan, Hema, Cuthbertson, Kevin, Baxter, Paul D., Foster, Richard, Sukumar, Piruthivi, Weightman, Andrew, Calaghan, Sarah C., Wheatcroft, Stephen B., Kearney, Mark T., Beech, David J.

“…Mammalian biology adapts to physical activity but the molecular mechanisms sensing the activity remain enigmatic. Recent studies have revealed how Piezo1…”
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Comparative Survival After Transapical, Direct Aortic, and Subclavian Transcatheter Aortic Valve Implantation (Data from the UK TAVI Registry) by Fröhlich, Georg M., MD, Baxter, Paul D., PhD, Malkin, Christopher J., MD, Scott, D. Julian A., MD, Moat, Neil E., MD, Hildick-Smith, David, MD, Cunningham, David, MD, MacCarthy, Philip A., PhD, Trivedi, Uday, Bsc, de Belder, Mark A., MD, Ludman, Peter F., MD, Blackman, Daniel J., MD

“…Many patients have iliofemoral vessel anatomy unsuitable for conventional transfemoral (TF) transcatheter aortic valve implantation (TAVI). Safe and practical…”
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Dose Dependency of Iatrogenic Glucocorticoid Excess and Adrenal Insufficiency and Mortality: A Cohort Study in England by Mebrahtu, Teumzghi F, Morgan, Ann W, Keeley, Adam, Baxter, Paul D, Stewart, Paul M, Pujades-Rodriguez, Mar

“…Abstract Context Adrenal insufficiency and Cushing syndrome are known adverse events of glucocorticoids. However, no population estimates of dose-related risks…”
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Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system by Baxter, Paul S., Bell, Karen F.S., Hasel, Philip, Kaindl, Angela M., Fricker, Michael, Thomson, Derek, Cregan, Sean P., Gillingwater, Thomas H., Hardingham, Giles E.

“…How the brain’s antioxidant defenses adapt to changing demand is incompletely understood. Here we show that synaptic activity is coupled, via the NMDA receptor…”
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Quenching Dynamics in CdSe Nanoparticles: Surface-Induced Defects upon Dilution by Hartmann, Lucia, Kumar, Abhishek, Welker, Matthias, Fiore, Angela, Julien-Rabant, Carine, Gromova, Marina, Bardet, Michel, Reiss, Peter, Baxter, Paul N.W, Chandezon, Frédéric, Pansu, Robert B

“…We have analyzed the decays of the fluorescence of colloidal CdSe quantum dots (QDs) suspensions during dilution and titration by the ligands. A ligand shell…”
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Latent class regression improves the predictive acuity and clinical utility of survival prognostication amongst chronic heart failure patients by Mbotwa, John L, Kamps, Marc de, Baxter, Paul D, Ellison, George T H, Gilthorpe, Mark S

“…The present study aimed to compare the predictive acuity of latent class regression (LCR) modelling with: standard generalised linear modelling (GLM); and GLMs…”
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Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism by Hasel, Philip, Dando, Owen, Jiwaji, Zoeb, Baxter, Paul, Todd, Alison C., Heron, Samuel, Márkus, Nóra M., McQueen, Jamie, Hampton, David W., Torvell, Megan, Tiwari, Sachin S., McKay, Sean, Eraso-Pichot, Abel, Zorzano, Antonio, Masgrau, Roser, Galea, Elena, Chandran, Siddharthan, Wyllie, David J. A., Simpson, T. Ian, Hardingham, Giles E.

“…The influence that neurons exert on astrocytic function is poorly understood. To investigate this, we first developed a system combining cortical neurons and…”
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Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology by Jiwaji, Zoeb, Tiwari, Sachin S., Avilés-Reyes, Rolando X., Hooley, Monique, Hampton, David, Torvell, Megan, Johnson, Delinda A., McQueen, Jamie, Baxter, Paul, Sabari-Sankar, Kayalvizhi, Qiu, Jing, He, Xin, Fowler, Jill, Febery, James, Gregory, Jenna, Rose, Jamie, Tulloch, Jane, Loan, Jamie, Story, David, McDade, Karina, Smith, Amy M., Greer, Peta, Ball, Matthew, Kind, Peter C., Matthews, Paul M., Smith, Colin, Dando, Owen, Spires-Jones, Tara L., Johnson, Jeffrey A., Chandran, Siddharthan, Hardingham, Giles E.

“…Alzheimer’s disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly understood. TRAP-seq translatome analysis of astrocytes in APP/PS1…”
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Supervised autonomy for online learning in human-robot interaction by Senft, Emmanuel, Baxter, Paul, Kennedy, James, Lemaignan, Séverin, Belpaeme, Tony

“…When a robot is learning it needs to explore its environment and how its environment responds on its actions. When the environment is large and there are a…”
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Synthesis of a Strained Acetylenic Macrocycle Incorporating a para-Oligo[2]cruciform Bridge Bent over Nanoscopic Dimensions: Structural, Electronic, Spectroscopic, and Ion-Sensing Properties by Baxter, Paul N. W., Gisselbrecht, Jean-Paul, Karmazin-Brelot, Lydia, Varnek, Alexandre, Allouche, Lionel

“…An Eglinton–Galbraith diethyne cyclization preferentially yielded a structurally unusual macrocycle, comprising a strained conjugated oligo[2]cruciform wire,…”
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Mixed-species RNA-seq for elucidation of non-cell-autonomous control of gene transcription by Qiu, Jing, Dando, Owen, Baxter, Paul S., Hasel, Philip, Heron, Samuel, Simpson, T. Ian, Hardingham, Giles E.

“…Transcriptomic changes induced in one cell type by another mediate many biological processes in the brain and elsewhere; however, achieving artifact-free…”
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Differential splicing choices made by neurons and astrocytes and their importance when investigating signal-dependent alternative splicing in neural cells by Baxter, Paul S, Dando, Owen, Hardingham, Giles E

“…A variety of proteins can be encoded by a single gene via the differential splicing of exons. In neurons this form of alternative splicing can be controlled by…”
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An Investigation into the Stephens–Castro Synthesis of Dehydrotriaryl[12]annulenes: Factors Influencing the Cyclotrimerization by Baxter, Paul N. W., Al Ouahabi, Abdelaziz, Karmazin, Lydia, Varnek, Alexandre, Strub, Jean‐Marc, Cianferani, Sarah

“…Detailed investigation into the CuX/base/phosphine modified Stephens–Castro syntheses of dehydrotriaryl[12]annulenes 1–3 have shown that cyclization is…”
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CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration by McKibbin, Martin, Ali, Manir, Bansal, Shveta, Baxter, Paul D, West, Kumi, Williams, Grange, Cassidy, Frances, Inglehearn, Chris F

“…To investigate an association between genotype for three single nucleotide polymorphisms strongly associated with the development of age-related macular…”
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Robot-Enhanced Therapy: Development and Validation of Supervised Autonomous Robotic System for Autism Spectrum Disorders Therapy by Cao, Hoang-Long, Esteban, Pablo G., Bartlett, Madeleine, Baxter, Paul, Belpaeme, Tony, Billing, Erik, Cai, Haibin, Coeckelbergh, Mark, Costescu, Cristina, David, Daniel, De Beir, Albert, Hernandez, Daniel, Kennedy, James, Liu, Honghai, Matu, Silviu, Mazel, Alexandre, Pandey, Amit, Richardson, Kathleen, Senft, Emmanuel, Thill, Serge, Van de Perre, Greet, Vanderborght, Bram, Vernon, David, Wakanuma, Kutoma, Yu, Hui, Zhou, Xiaolong, Ziemke, Tom

“…Robot-assisted therapy (RAT) offers potential advantages for improving the social skills of children with autism spectrum disorders (ASDs). This article…”
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