Search Results - "BAUMGOLD, J"

A Malignant Melanoma Imaging Agent: Synthesis, Characterization, In Vitro Binding and Biodistribution of Iodine-125-(2-Piperidinylaminoethyl)4-Iodobenzamide by John, C.S, Bowen, W.D, Saga, T, Kinuya, S, Vilner, B.J, Baumgold, J, Paik, C.H, Reba, R.C, Neumann, R.D, Varma, V.M, McAfee, J.G

“…In order to develop improved radiopharmaceuticals for imaging malignant melanoma, we have synthesized and characterized 125I-and 131I-labeled…”
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An agonist that is selective for adenylate cyclase-coupled muscarinic receptors by Baumgold, J, Drobnick, A

“…Compound BM5 [N-methyl-N(1-methyl-4-pyrrolidino-2-butynyl) acetamide] has previously been described as an agonist at postsynaptic muscarinic receptors and as…”
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Relationship between desensitization and sequestration of muscarinic cholinergic receptors in two neuronal cell lines by Baumgold, J, Cooperman, B B, White, T M

“…Agonist-induced sequestration and desensitization of muscarinic receptors was studied in two cell lines that each express differentially-coupled receptors. The…”
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Membrane-associated cytoskeletal proteins in squid giant axons by Baumgold, J, Ierakawa, S, Iwasa, K, Gainer, H

“…Cytoskeletal proteins (e.g., tubulin, actin, and neurofilament proteins) in the squid giant axon are separable into KF-soluble and -insoluble forms. The…”
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Muscarinic receptor subtype selectivity of novel heterocyclic QNB analogues by Baumgold, J, Cohen, V I, Paek, R, Reba, R C

“…In an effort at synthesizing centrally-active subtype-selective antimuscarinic agents, we derivatized QNB (quinuclidinyl benzilate), a potent muscarinic…”
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Appearance of [3H]saxitoxin binding sites in developing rat brain by Baumgold, J, Zimmerman, I, Bambrick, L

“…The binding of [3H]saxitoxin to a crude membrane fraction from rat brains of various ages was determined. We found that at two days before birth, the maximum…”
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Loss of pirenzepine regional selectivity following solubilization and partial purification of the putative M1 and M2 muscarinic receptor subtypes by Baumgold, J, Merril, C, Gershon, E S

“…Pirenzepine inhibition of [3H]N-methylscopolamine ([3H]NMS) binding was studied in membranous, digitonin-solubilized, and partially purified muscarinic…”
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Development of sodium channels during differentiation of chick skeletal muscle in culture. I. Binding studies by Baumgold, J, Parent, JB, Spector, I

“…[125I]Scorpion toxin and [3H]saxitoxin, two neurotoxins that bind specifically to different sites on sodium channels, were used to monitor the development of…”
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Tetrodotoxin affects submembranous cytoskeletal proteins in perfused squid giant axons by Baumgold, J, Gallant, P, Terakawa, S, Pant, H

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Muscarinic receptor-mediated stimulation of adenylyl cyclase by Baumgold, J

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Functionalized congener approach for the design of novel muscarinic agents. Synthesis and pharmacological evaluation of N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl] amides by Bradbury, Barton J, Baumgold, Jesse, Jacobson, Kenneth A

“…A functionalized congener approach was used to design ligands for muscarinic cholinergic receptors (mAChRs). A series of omega-functionalized alkyl amides of…”
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EXPERIENCE OF FREEDOM TO CHOOSE IN MENTAL HEALTH, NEUROSIS AND PSYCHOSIS by BAUMGOLD, J, TEMERLIN, M K, RAGLAND, R

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Differences in the functional responses of two cell lines each expressing Pi-hydroylsis-coupled muscarinic receptors by BAUMGOLD, J, PAEK, R

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Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding by Baumgold, J, Nikodijevic, O, Jacobson, K A

“…The penetration of the adenosine antagonists 8-cyclopentyl-1,3-dimethylxanthine (CPT), 8-cyclopentyl-1,3-dipropylxanthine (CPX), 8-(p-sulfophenyltheophylline…”
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Changes in the ratio of two separate toxin binding sites on the sodium channel protein during rat brain development by Baumgold, J

“…The development of two separate toxin binding sites from sodium channels of rat brain was studied. Whereas [3H]saxitoxin binding developed gradually, reaching…”
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Effects of verapamil on the binding characteristics of muscarinic receptor subtypes by Baumgold, J

“…The calcium channel antagonist verapamil inhibited [3H]N-methyl scopolamine ([3H]NMS ) binding to muscarinic receptors from both rat brain cortex, an area rich…”
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Pharmacological differences between muscarinic receptors coupled to phosphoinositide turnover and those coupled to adenylate cyclase inhibition by Baumgold, J, White, T

“…Pharmacological differences between muscarinic cholinergic receptors coupled to phosphoinositide turnover and those coupled to adenylate cyclase were studied…”
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Muscarinic receptors in brain from four strains of inbred mice by BAUMGOLD, J

“…The density of brain muscarinic receptors from four strains of inbred mice was determined. C57BL/6J mice had a significantly higher density of muscarinic…”
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Muscarinic receptor-mediated inhibition of mitogenesis via a protein kinase C-independent mechanism in M1-transfected A9 L cells by Baumgold, J, Dyer, K

“…Previous studies have shown that activation of various PI-coupled receptors stimulates DNA synthesis in some cells, and inhibits DNA synthesis in others. In…”
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Structure-activity relationships of imperialine derivatives and their anticholinergic activity by Atta-ur-Rahman, Choudhary, M I, Farooq, A, Anjum, S, Baumgold, J, Sener, B

“…In order to check the structure-activity relationship and prepare more potent derivatives of imperialine with anticholinergic activity, imperialinol (2), 3…”
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