Search Results - "BAUMANN, MICHAEL H."

Misuse of Novel Synthetic Opioids: A Deadly New Trend by Prekupec, Matthew P., Mansky, Peter A., Baumann, Michael H.

“…Novel synthetic opioids (NSOs) include various analogs of fentanyl and newly emerging non-fentanyl compounds. Together with illicitly manufactured fentanyl…”
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Awash in a sea of 'bath salts': implications for biomedical research and public health by Baumann, Michael H.

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Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3,4-methylenedioxypyrovalerone (MDPV) by Marusich, Julie A., Antonazzo, Kateland R., Wiley, Jenny L., Blough, Bruce E., Partilla, John S., Baumann, Michael H.

“…There has been a dramatic rise in the abuse of synthetic cathinones known as “bath salts,” including 3,4-methylenedioxypyrovalerone (MDPV), an analog linked to…”
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The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue by BAUMANN, Michael H, AYESTAS, Mario A, PARTILIA, John S, SINK, Jacqueline R, SHULGIN, Alexander T, DALEY, Paul F, BRANDT, Simon D, ROTHMAN, Richard B, RUOHO, Arnold E, COZZI, Nicholas V

“…The nonmedical use of 'designer' cathinone analogs, such as 4-methylmethcathinone (mephedrone) and 3,4-methylenedioxymethcathinone (methylone), is increasing…”
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Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive 'Bath Salts' Products by BAUMANN, Michael H, PARTILLA, John S, BRANDT, Simon D, TELLA, Srihari R, COZZI, Nicholas V, SCHINDLER, Charles W, LEHNER, Kurt R, THORNDIKE, Eric B, HOFFMAN, Alexander F, HOLY, Marion, ROTHMAN, Richard B, GOLDBERG, Steven R, LUPICA, Carl R, SITTE, Harald H

“…The abuse of psychoactive 'bath salts' containing cathinones such as 3,4-methylenedioxypyrovalerone (MDPV) is a growing public health concern, yet little is…”
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Repeated Exposure to the “Spice” Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats by Elmore, Joshua S., Baumann, Michael H.

“…Naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) is a synthetic compound found in psychoactive “spice” products that activates cannabinoid receptors…”
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Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity by Espiritu, Michael J, Taylor, Jonathan K, Sugai, Christopher K, Thapa, Parashar, Loening, Nikolaus M, Gusman, Emma, Baoanan, Zenaida G, Baumann, Michael H, Bingham, Jon-Paul

“…χ-Conotoxins are known for their ability to selectively inhibit norepinephrine transporters, an ability that makes them potential leads for treating various…”
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Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil by Zolkowska, Dorota, Jain, Raka, Rothman, Richard B, Partilla, John S, Roth, Bryan L, Setola, Vincent, Prisinzano, Thomas E, Baumann, Michael H

“…Modafinil is prescribed for numerous medical conditions, but the drug's mechanism of action is unclear. Here, we examined the interaction of modafinil with…”
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Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents by Tuv, Silja Skogstad, Bergh, Marianne Skov-Skov, Andersen, Jannike Mørch, Steinsland, Synne, Vindenes, Vigdis, Baumann, Michael H, Huestis, Marilyn A, Bogen, Inger Lise

“…Methiopropamine is a novel psychoactive substance (NPS) that is associated with several cases of clinical toxicity, yet little information is available…”
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In vivo effects of amphetamine analogs reveal evidence for serotonergic inhibition of mesolimbic dopamine transmission in the rat by Baumann, Michael H, Clark, Robert D, Woolverton, William L, Wee, Sunmee, Blough, Bruce E, Rothman, Richard B

“…Evidence suggests that elevations in extracellular serotonin (5-HT) in the brain can diminish stimulant effects of dopamine (DA). To assess this proposal, we…”
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Balance between Dopamine and Serotonin Release Modulates Behavioral Effects of Amphetamine-Type Drugs by ROTHMAN, RICHARD B., BAUMANN, MICHAEL H.

“…:  The abuse of illicit stimulants is a worldwide crisis, yet few medicines are available for treating stimulant addiction. We have advocated the idea of…”
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Ventilator-associated events: the new definition by Raoof, Suhail, Baumann, Michael H

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U-47700 and Its Analogs: Non-Fentanyl Synthetic Opioids Impacting the Recreational Drug Market by Baumann, Michael H, Tocco, Graziella, Papsun, Donna M, Mohr, Amanda L, Fogarty, Melissa F, Krotulski, Alex J

“…The recreational use of opioid drugs is a global threat to public health and safety. In particular, an epidemic of opioid overdose fatalities is being driven…”
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Automated Computer Software Assessment of 5‑Hydroxytryptamine 2A Receptor-Mediated Head Twitch Responses from Video Recordings of Mice by Glatfelter, Grant C., Chojnacki, Michael R., McGriff, Shelby A., Wang, Tianpeng, Baumann, Michael H.

“…Psychedelics are a class of drugs that produce unique subjective effects via agonist actions at the 5-hydroxytryptamine 2A receptor (5-HT2A). The…”
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Corrigendum: Cell-Based Radiotracer Binding and Uptake Inhibition Assays: A Comparison of In Vitro Methods to Assess the Potency of Drugs That Target Monoamine Transporters by Ilic, Marija, Maier, Julian, Holy, Marion, Jaentsch, Kathrin, Liechti, Matthias E, Lubec, Gert, Baumann, Michael H, Sitte, Harald H, Luethi, Dino

“…[This corrects the article DOI: 10.3389/fphar.2020.00673.]…”
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Cell-Based Radiotracer Binding and Uptake Inhibition Assays: A Comparison of In Vitro Methods to Assess the Potency of Drugs That Target Monoamine Transporters by Ilic, Marija, Holy, Marion, Jaentsch, Kathrin, Liechti, Matthias E, Lubec, Gert, Baumann, Michael H, Sitte, Harald H, Luethi, Dino

“…High-affinity monoamine transporters are targets for prescribed medications and stimulant drugs of abuse. Therefore, assessing monoamine transporter activity…”
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An n-3 Fatty Acid Deficiency Impairs Rat Spatial Learning in the Barnes Maze by Fedorova, Irina, Hussein, Nahed, Baumann, Michael H, Di Martino, Carmine, Salem, Norman

“…In this study, the authors demonstrate that rats with n-3 fatty acid deficiency display spatial learning deficits in the Barnes circular maze. Dams were…”
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Interaction of amphetamines and related compounds at the vesicular monoamine transporter by Partilla, John S, Dempsey, Allison G, Nagpal, Ameet S, Blough, Bruce E, Baumann, Michael H, Rothman, Richard B

“…Amphetamine-type agents interact with the vesicular monoamine transporter type 2 (VMAT(2)), promoting the release of intravesicular neurotransmitter and an…”
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Cadherin 13: human cis -regulation and selectively-altered addiction phenotypes and cerebral cortical dopamine in knockout mice by Drgonova, Jana, Walther, Donna, Hartstein, G Luke, Bukhari, Mohammad O, Baumann, Michael H, Katz, Jonathan, Hall, Frank Scott, Arnold, Elizabeth R, Flax, Shaun, Riley, Anthony, Rivero-Martin, Olga, Lesch, Klaus-Peter, Troncoso, Juan, Ranscht, Barbara, Uhl, George R

“…The cadherin 13 (CDH13) gene encodes a cell adhesion molecule likely to influence development and connections of brain circuits that modulate addiction,…”
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Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat by BAUMANN, Michael H, ZOLKOWSKA, Dorota, KIM, Insook, SCHEIDWEILER, Karl B, ROTHMAN, Richard B, HUESTIS, Marilyn A

“…Based on animal data, there is speculation that (±)-3,4-methylenedioxymethamphetamine (MDMA) is neurotoxic to humans. Extrapolation of MDMA findings from…”
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