Search Results - "BAULIDA, Josep"
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Epithelial‐to‐mesenchymal transition transcription factors in cancer‐associated fibroblasts
Published in Molecular oncology (01-07-2017)“…Beyond inducing epithelial‐to‐mesenchymal transcription (EMT), transcriptional factors of the Snail, ZEB and Twist families (EMT‐TFs) control global plasticity…”
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Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis
Published in Cancer research (Chicago, Ill.) (01-11-2016)“…Snail1 transcriptional factor is essential for triggering epithelial-to-mesenchymal transition (EMT) and inducing tumor cell invasion. We report here an…”
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Formation of an invasion-permissive matrix requires TGFβ/SNAIL1-regulated alternative splicing of fibronectin
Published in Breast cancer research : BCR (14-11-2023)“…As in most solid cancers, the emergence of cells with oncogenic mutations in the mammary epithelium alters the tissue homeostasis. Some soluble factors, such…”
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Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells
Published in Oncogene (23-09-2004)“…Expression of Snail transcriptional factor is a determinant in the acquisition of a mesenchymal phenotype by epithelial tumor cells. However, the regulation of…”
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The Hypoxia-controlled FBXL14 Ubiquitin Ligase Targets SNAIL1 for Proteasome Degradation
Published in The Journal of biological chemistry (05-02-2010)“…The transcription factor SNAIL1 is a master regulator of epithelial to mesenchymal transition. SNAIL1 is a very unstable protein, and its levels are regulated…”
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Snail1-driven plasticity of epithelial and mesenchymal cells sustains cancer malignancy
Published in Biochimica et biophysica acta (01-08-2015)“…The transcription factor Snail1 induces epithelial-to-mesenchymal transition (EMT) in tumor epithelial cells, a process associated with the emergence of…”
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Correction: Gamma-Secretase-Dependent and -Independent Effects of Presenilin1 on β-Catenin·Tcf-4 Transcriptional Activity
Published in PloS one (2016)“…[This corrects the article DOI: 10.1371/journal.pone.0004080.]…”
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Phosphorylation Regulates the Subcellular Location and Activity of the Snail Transcriptional Repressor
Published in Molecular and Cellular Biology (01-07-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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All ErbB Receptors Other Than the Epidermal Growth Factor Receptor Are Endocytosis Impaired
Published in The Journal of biological chemistry (01-03-1996)“…Four transmembrane tyrosine kinases constitute the ErbB receptor family: the epidermal growth factor (EGF) receptor, ErbB-2, ErbB-3, and ErbB-4. We have…”
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Colon Cancer-associated Fibroblast Establishment and Culture Growth
Published in Bio-protocol (01-04-2016)“…Cancer-associated fibroblasts (CAFs) are one of the major players in tumor-stroma crosstalk. Findings in experimental studies suggest important roles for CAFs…”
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Gamma-secretase-dependent and -independent effects of presenilin1 on beta-catenin.Tcf-4 transcriptional activity
Published in PloS one (2008)“…Presenilin1 (PS1) is a component of the gamma-secretase complex mutated in cases of Familial Alzheimer's disease (FAD). PS1 is synthesized as a 50 kDa peptide…”
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Selective Cleavage of the Heregulin Receptor ErbB-4 by Protein Kinase C Activation
Published in The Journal of biological chemistry (02-08-1996)“…The 180-kDa transmembrane tyrosine kinase ErbB-4 is a receptor for the growth factor heregulin. 125I-Heregulin binding to NIH 3T3 cells overexpressing the…”
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Snail1 controls cooperative cell plasticity during metastasis
Published in Oncoscience (2015)Get full text
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14
The p65 subunit of NF-κB and PARP1 assist Snail1 in activating fibronectin transcription
Published in Journal of cell science (15-12-2011)“…Snail1 is a transcriptional repressor of E-cadherin that triggers epithelial-mesenchymal transition (EMT). Here, we report assisted Snail1 interaction with the…”
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Glutamine-Directed Migration of Cancer-Activated Fibroblasts Facilitates Epithelial Tumor Invasion
Published in Cancer research (Chicago, Ill.) (15-01-2021)“…Tumors are complex tissues composed of transformed epithelial cells as well as cancer-activated fibroblasts (CAF) that facilitate epithelial tumor cell…”
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Cooperation, amplification, and feed-back in epithelial–mesenchymal transition
Published in Biochimica et biophysica acta (01-04-2012)“…The epithelial to mesenchymal transition (EMT) consists of a rapid change of cell phenotype, characterized by the loss of epithelial traits and the acquisition…”
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Increased glucose transport in ras-transformed fibroblasts: a possible role for N-glycosylation of GLUT1
Published in FEBS letters (05-05-1997)“…2-Deoxyglucose uptake was enhanced in ts371 KiMuSV-NRK cells when growing at the permissive temperature to allow the expression of a transforming p21 ras…”
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Snail1-expressing fibroblasts in the tumor microenvironment display mechanical properties that support metastasis
Published in Cancer research (Chicago, Ill.) (15-01-2015)“…Crosstalk between tumor and stromal cells in the tumor microenvironment alter its properties in ways that facilitate the invasive behavior of tumor cells…”
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Formation of an invasion-permissive matrix requires TGF[beta]/SNAIL1-regulated alternative splicing of fibronectin
Published in Breast cancer research : BCR (14-11-2023)“…Background As in most solid cancers, the emergence of cells with oncogenic mutations in the mammary epithelium alters the tissue homeostasis. Some soluble…”
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20
Abrogation of myofibroblast activities in metastasis and fibrosis by methyltransferase inhibition
Published in International journal of cancer (01-12-2019)“…Myofibroblasts are a population of highly contractile fibroblasts that express and require the activity of the transcription factor Snail1. Cancer‐associated…”
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