Search Results - "BAUER, Hannelore"
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Tight Junctions of the Blood-Brain Barrier - A Molecular Gatekeeper
Published in CNS & neurological disorders drug targets (01-01-2016)“…A tight regulation of the neuroparenchymal microenvironment is imperative for proper neurological function. The flux of blood-borne ions and solutes is…”
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The Blood-Brain Barrier and Its Intercellular Junctions in Age-Related Brain Disorders
Published in International journal of molecular sciences (03-11-2019)“…With age, our cognitive skills and abilities decline. Maybe starting as an annoyance, this decline can become a major impediment to normal daily life. Recent…”
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Oxidative stress and blood-brain barrier dysfunction under particular consideration of matrix metalloproteinases
Published in Antioxidants & redox signaling (01-09-2011)“…A cell's "redox" (oxidation and reduction) state is determined by the sum of all redox processes yielding reactive oxygen species (ROS), reactive nitrogen…”
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Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases
Published in PloS one (02-06-2011)“…Malignant melanoma represents the third common cause of brain metastasis, having the highest propensity to metastasize to the brain of all primary neoplasms in…”
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Pharmaceutical Targeting of the Brain
Published in Current pharmaceutical design (01-01-2016)“…Besides being indispensable for the protection and nutrition of the central nervous system (CNS), blood-brain barrier (BBB)-forming cerebral endothelial cells…”
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Brain pericyte plasticity as a potential drug target in CNS repair
Published in Drug discovery today (01-05-2013)“…► Brain pericytes represent a pivotal cell type of the neurovascular niche. ► Brain pericytes have mesenchymal and neural stem cells features. ► Brain…”
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Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach
Published in PloS one (21-03-2012)“…Exchange mechanisms across the blood-cerebrospinal fluid (CSF) barrier in the choroid plexuses within the cerebral ventricles control access of molecules to…”
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Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach
Published in PloS one (02-07-2013)“…We provide comprehensive identification of embryonic (E15) and adult rat lateral ventricular choroid plexus transcriptome, with focus on junction-associated…”
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Cellular specificity of the blood-CSF barrier for albumin transfer across the choroid plexus epithelium
Published in PloS one (11-09-2014)“…To maintain the precise internal milieu of the mammalian central nervous system, well-controlled transfer of molecules from periphery into brain is required…”
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Correction: Mechanisms That Determine the Internal Environment of the Developing Brain: A Transcriptomic, Functional and Ultrastructural Approach
Published in PloS one (19-01-2016)Get full text
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The Tight Junction Protein ZO-2 Localizes to the Nucleus and Interacts with the Heterogeneous Nuclear Ribonucleoprotein Scaffold Attachment Factor-B
Published in The Journal of biological chemistry (24-01-2003)“…Zonula occludens proteins (ZOPs), currently comprising ZO-1, ZO-2, and ZO-3, belong to the family of membrane-associated guanylate kinase homologue (MAGUK)…”
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The Tight Junction-specific Protein Occludin Is a Functional Target of the E3 Ubiquitin-protein Ligase Itch
Published in The Journal of biological chemistry (22-03-2002)“…Tight junctions create a highly selective diffusion barrier between epithelial and endothelial cells by preventing the free passage of molecules and ions…”
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"You Shall Not Pass"-tight junctions of the blood brain barrier
Published in Frontiers in neuroscience (03-12-2014)“…The structure and function of the barrier layers restricting the free diffusion of substances between the central nervous system (brain and spinal cord) and…”
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Adipose Stem Cells from Lipedema and Control Adipose Tissue Respond Differently to Adipogenic Stimulation In Vitro
Published in Plastic and reconstructive surgery (1963) (01-09-2019)“…Lipedema is characterized by localized accumulation of fat in the extremities, which is typically unresponsive to dietary regimens or physical activity…”
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Lipedema: The use of cultured adipocytes for identification of diagnostic markers
Published in Plastic and reconstructive surgery (1963) (01-11-2023)“…Lipedema is a progressive disease, diagnosed most often in women, which is characterized by the unproportionate and symmetrical distribution of adipose tissue…”
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Adipose Stem Cells from Lipedema and Control Adipose Tissue Respond Differently to Adipogenic Stimulation In Vitro
Published in Plastic and reconstructive surgery (1963) (01-09-2019)“…BACKGROUND:Lipedema is characterized by localized accumulation of fat in the extremities, which is typically unresponsive to dietary regimes or physical…”
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Lipedema Research-Quo Vadis?
Published in Journal of personalized medicine (31-12-2022)“…When studying the current literature, one might get the impression that lipedema is a "modern" disease, with increasing incidence and augmenting prevalence…”
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Bupivacaine Induces Short-Term Alterations and Impairment in Rat Tendons
Published in The American journal of sports medicine (01-06-2013)“…Background: Toxicity of the local anesthetic bupivacaine (BV) has been a matter of debate across medical fields. Numerous in vitro studies demonstrate…”
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Incorporation of β-Galactosidase-Expressing Endothelial Cells into the Skeletal Muscle Microvascular Bed of Mice
Published in Cell transplantation (01-01-1997)“…Cloned murine endothelial cells (cEC) were used as a carrier system for introducing a foreign gene into the microvascular bed of the hind limb of inbred mice…”
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Role of Rho/ROCK signaling in the interaction of melanoma cells with the blood-brain barrier
Published in Pigment cell and melanoma research (01-01-2014)“…Summary We have investigated the role of the Rho/ROCK signaling pathway in the interaction of metastatic melanoma cells with the brain endothelium. ROCK…”
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