Search Results - "BATTISTINI, Angela"
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HIV-1 latency: an update of molecular mechanisms and therapeutic strategies
Published in Viruses (14-04-2014)“…The major obstacle towards HIV-1 eradication is the life-long persistence of the virus in reservoirs of latently infected cells. In these cells the proviral…”
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IκB kinase-ε-mediated phosphorylation triggers IRF-1 degradation in breast cancer cells
Published in Neoplasia (New York, N.Y.) (01-10-2020)“…Interferon Regulatory Factors (IRFs) are key regulators of immunity, cell survival and apoptosis. IRF transcriptional activity and subcellular localization are…”
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3
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia
Published in The Journal of experimental medicine (14-04-2008)“…Aberrant signal transduction contributes substantially to leukemogenesis. The Janus kinase 1 (JAK1) gene encodes a cytoplasmic tyrosine kinase that…”
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4
HIV-1 Tat Recruits HDM2 E3 Ligase To Target IRF-1 for Ubiquitination and Proteasomal Degradation
Published in mBio (18-10-2016)“…In addition to its ability to regulate HIV-1 promoter activation, the viral transactivator Tat also functions as a determinant of pathogenesis and disease…”
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IκB Kinase ε Targets Interferon Regulatory Factor 1 in Activated T Lymphocytes
Published in Molecular and Cellular Biology (01-03-2014)“…Classifications Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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IRF-8 Controls Melanoma Progression by Regulating the Cross Talk between Cancer and Immune Cells within the Tumor Microenvironment
Published in Neoplasia (New York, N.Y.) (01-12-2012)“…The transcription factor interferon regulatory factor-8 (IRF-8) is crucial for myeloid cell development and immune response and also acts as a tumor suppressor…”
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Reactogenicity of BNT162b2 mRNA COVID-19 Vaccine in a Young Working Age Population: A Survey among Medical School Residents, within a Mass Vaccination Campaign, in a Regional Reference Teaching Hospital in Italy
Published in Vaccines (Basel) (03-11-2021)“…Vaccinations are a key prevention measure in fighting the COVID-19 pandemic. The BNT162b2 mRNA vaccine (BioNTech/Pfizer), the first to receive authorization,…”
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IRF-1 Is Required for Full NF-κB Transcriptional Activity at the Human Immunodeficiency Virus Type 1 Long Terminal Repeat Enhancer
Published in Journal of Virology (01-04-2008)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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9
Repression of Interferon Regulatory Factor 1 by Hepatitis C Virus Core Protein Results in Inhibition of Antiviral and Immunomodulatory Genes
Published in Journal of Virology (01-01-2007)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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10
An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones
Published in BMC genomics (04-10-2011)“…Infections with hepatitis C virus (HCV) progress to chronic phase in 80% of patients. To date, the effect produced by HCV on the expression of microRNAs (miRs)…”
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Human Papillomavirus Type 16 E5 Protein Induces Expression of Beta Interferon through Interferon Regulatory Factor 1 in Human Keratinocytes
Published in Journal of Virology (01-05-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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12
Adherence to international and national recommendations for the prevention of surgical site infections in Italy: Results from an observational prospective study in elective surgery
Published in American journal of infection control (01-12-2012)“…Background An observational prospective study of the perioperative procedures for prevention of surgical site infections (SSIs) was carried out in a tertiary…”
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13
HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators
Published in Oncogene (15-02-2001)“…Human herpes virus 8 (HHV-8) has developed unique mechanisms for altering cellular proliferative and apoptotic control pathways by incorporating viral homologs…”
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14
Interferon-γ receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death
Published in Journal of leukocyte biology (01-12-2001)“…Theheterodimeric interferon (IFN)‐γ receptor (IFN‐γR) is formed of two chains. Here we show that the binding chain (IFN‐γR1) was highly expressed on the…”
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15
Role of Acetylases and Deacetylase Inhibitors in IRF-1-Mediated HIV-1 Long Terminal Repeat Transcription
Published in Annals of the New York Academy of Sciences (01-12-2004)“…: There is strong evidence that both transcriptional activation and silencing are mediated through the recruitment of enzymes that control reversible protein…”
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IFN-γ and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation
Published in International immunology (01-07-2000)“…NO is a labile radical involved in several immunological, antimicrobial and inflammatory processes. In macrophages, NO formation is catalyzed by the…”
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Interferon regulatory factor-2 drives megakaryocytic differentiation
Published in Biochemical journal (15-01-2004)“…IRFs [IFN (interferon) regulatory factors] constitute a family of transcription factors involved in IFN signalling and in the development and differentiation…”
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Interferon regulatory factors in hematopoietic cell differentiation and immune regulation
Published in Journal of interferon & cytokine research (01-12-2009)“…Members of the interferon regulatory factor (IRF) family are transcription factors implicated in the regulation of a variety of biological processes…”
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Interleukin-12 Induces Expression of Interferon Regulatory Factor-1 via Signal Transducer and Activator of Transcription-4 in Human T Helper Type 1 Cells
Published in The Journal of biological chemistry (05-03-1999)“…IRF-1-deficient mice show a striking defect in the development of T helper 1 (Th1) cells. In the present report, we investigate the expression of IRF-1 during…”
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The activity of the CCAAT-box binding factor NF-Y is modulated through the regulated expression of its a subunit during monocyte to macrophage differentiation : Regulation of tissue-specific genes through a ubiquitous transcription factor
Published in Blood (15-01-1999)“…In this study, we analyzed the regulation of NF-Y expression during human monocyte to macrophage maturation. NF-Y is a ubiquitous and evolutionarily conserved…”
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