Search Results - "BATRA, S"

Membrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cells by Bafna, S, Kaur, S, Batra, S K

“…Mucins (MUC) are high molecular weight O-linked glycoproteins whose primary functions are to hydrate, protect, and lubricate the epithelial luminal surfaces of…”
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Gut permeability and mucosal inflammation: bad, good or context dependent by Ahmad, R, Sorrell, M F, Batra, S K, Dhawan, P, Singh, A B

“…Inflammatory bowel disease (IBD) is a multifactorial disease. A breach in the mucosal barrier, otherwise known as “leaky gut,” is alleged to promote mucosal…”
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MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells by Ponnusamy, M P, Lakshmanan, I, Jain, M, Das, S, Chakraborty, S, Dey, P, Batra, S K

“…The acquisition of invasiveness in ovarian cancer (OC) is accompanied by the process of epithelial-to-mesenchymal transition (EMT). The MUC4 mucin is…”
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Stem Cells: A Revolution in Therapeutics-Recent Advances in Stem Cell Biology and Their Therapeutic Applications in Regenerative Medicine and Cancer Therapies by Mimeault, M, Hauke, R, Batra, S K

“…Basic and clinical research accomplished during the last few years on embryonic, fetal, amniotic, umbilical cord blood, and adult stem cells has constituted a…”
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Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survival by Joshi, S, Kumar, S, Ponnusamy, M P, Batra, S K

“…Pancreatic cancer (PC) and associated pre-neoplastic lesions have been reported to be hypoxic, primarily due to hypovascular nature of PC. Though the presence…”
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Modification of red mud by acid treatment and its application for CO removal by Sushil, Snigdha, Batra, Vidya S.

“…► Acid treated red mud was more active than as-received red mud for CO oxidation. ► High surface area and presence of hydroxylated iron oxide contributed to…”
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Activation of ATM Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells by Sahu, R P, Batra, S, Srivastava, S K

“…Curcumin has been shown to inhibit the growth of various types of cancer cells; however, at concentrations much above the clinically achievable levels in…”
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Recent Advances on the Molecular Mechanisms Involved in the Drug Resistance of Cancer Cells and Novel Targeting Therapies by Mimeault, M, Hauke, R, Batra, SK

“…This review summarizes the recent knowledge obtained on the molecular mechanisms involved in the intrinsic and acquired resistance of cancer cells to current…”
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Interplay between proteasome function and inflammatory responses in e-cig vapor condensate-challenged lung epithelial cells by Begum, R., Thota, S., Batra, S.

“…Exposure to cigarettes and other nicotine-based products results in persistent inflammation in the lung. In recent years, electronic cigarettes (e-cigs) have…”
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Differences in the path to exit the ribosome across the three domains of life by Dao Duc, Khanh, Batra, Sanjit S, Bhattacharya, Nicholas, Cate, Jamie H D, Song, Yun S

“…Abstract The ribosome exit tunnel is an important structure involved in the regulation of translation and other essential functions such as protein folding. By…”
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Analysis of comorbidities and objective parameters in refractory chronic rhinosinusitis by Batra, Pete S., Tong, Liyue, Citardi, Martin J.

“…Objectives/Hypothesis The objective of this study was to construct the clinical profile of patients with chronic rhinosinusitis (CRS) with/without polyposis…”
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Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation by Souchek, J J, Baine, M J, Lin, C, Rachagani, S, Gupta, S, Kaur, S, Lester, K, Zheng, D, Chen, S, Smith, L, Lazenby, A, Johansson, S L, Jain, M, Batra, S K

“…Background: Despite its promise as a highly useful therapy for pancreatic cancer (PC), the addition of external beam radiation therapy to PC treatment has…”
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Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway by Senapati, S, Rachagani, S, Chaudhary, K, Johansson, S L, Singh, R K, Batra, S K

“…An elevated level of macrophage inhibitory cytokine-1 (MIC-1) is reported in the sera of patients with metastatic prostate cancer compared with that of benign…”
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Impact of long-term zero till wheat on soil physical properties and wheat productivity under rice―wheat cropping system by SINGH, Ajeet, PHOGAT, V. K, DAHIYA, Rita, BATRA, S. D

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Loss of claudin-3 expression induces IL6/gp130/Stat3 signaling to promote colon cancer malignancy by hyperactivating Wnt/β-catenin signaling by Ahmad, R, Kumar, B, Chen, Z, Chen, X, Müller, D, Lele, S M, Washington, M K, Batra, S K, Dhawan, P, Singh, A B

“…The hyperactivated Wnt/β-catenin signaling acts as a switch to induce epithelial to mesenchymal transition and promote colorectal cancer. However, due to its…”
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Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer by Das, S, Rachagani, S, Sheinin, Y, Smith, L M, Gurumurthy, C B, Roy, H K, Batra, S K

“…MUC4, a large transmembrane mucin normally expressed in the small and large intestine, is differentially expressed during inflammatory and malignant conditions…”
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Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin by Bafna, S, Kaur, S, Momi, N, Batra, S K

“…Background: A major obstacle to the successful management of pancreatic cancer is to acquire resistance to the existing chemotherapeutic agents. Resistance to…”
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Interplay of distinct growth factors during epithelial–mesenchymal transition of cancer progenitor cells and molecular targeting as novel cancer therapies by Mimeault, M., Batra, S. K.

“…In this review, we describe the critical functions assumed by the interplay of epidermal growth factor, hedgehog, Wnt/β-catenin, tumor growth factor-β and…”
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MUC16 induced rapid G2 M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells by Lakshmanan, I, Ponnusamy, M P, Das, S, Chakraborty, S, Haridas, D, Mukhopadhyay, P, Lele, S M, Batra, S K

“…MUC16/CA125 is a tumor marker currently used in clinics for the follow-up of patients with ovarian cancer. However, MUC16 expression is not entirely restricted…”
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MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling by Lakshmanan, I, Rachagani, S, Hauke, R, Krishn, S R, Paknikar, S, Seshacharyulu, P, Karmakar, S, Nimmakayala, R K, Kaushik, G, Johansson, S L, Carey, G B, Ponnusamy, M P, Kaur, S, Batra, S K, Ganti, A K

“…MUC5AC is a secretory mucin aberrantly expressed in various cancers. In lung cancer, MUC5AC is overexpressed in both primary and metastatic lesions; however,…”
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